Vážený zákazníci, rádi bychom Vás pozvali na odborný seminář &amp; webinář Trendy mikrobiologického testování listerií v potravinářství.Tato odborná událost je určena zejména manažerům kvality, vedoucím laboratoří a výroby, stejně jako dalším odborníkům působícím v oblasti potravinářské mikrobiologie.<ul><li>Datum konání: 21. 4. 2026 od 9:00 do 13:00</li><li>Místo konání: prostory Spaces Parkview (Pujmanové 1753/10a, 140 00 Praha 4-Nusle) &amp; online</li><li>Forma účasti:&nbsp;<ul><li>osobní (doporučeno zejména pro manažery kvality a vedoucí laboratoří či výroby)</li><li>online (s možností následného přehrání záznamu)</li></ul></li></ul><h4>Témata semináře:</h4><ul><li>Prediktivní mikrobiologické modely v praxi – Ing. Naděžda Kulišťáková Cahlíková, Ph.D. (Eurofins)</li><li>Alternativní metody v mikrobiologii potravin – Patrik Dočkal (Thermo Fisher Scientific)</li><li>Přístup Státní veterinární správy k nové legislativě pro vyšetřování Listeria monocytogenes – Mgr. Michaela Zlámalová (Státní veterinární správa)</li><li>Praktické zkušenosti s testováním listerie ve výrobě – RNDr. Hana Bulawová (Státní veterinární ústav Jihlava)</li><li>Diskuse u kulatého stolu – Mgr. Lenka Bartošová, Ph.D. (Státní zemědělská a potravinářská inspekce), RNDr. Hana Bulawová (Státní veterinární ústav Jihlava) a Mgr. Michaela Zlámalová (Státní veterinární správa), moderuje Ing. Jan Pivoňka Ph.D. (Česká technologická platforma pro potraviny)&nbsp;</li></ul><h3>Registrace</h3><blockquote><ul><li><a target="_blank" rel="noopener noreferrer" href="https://forms.office.com/pages/responsepage.aspx?id=LXJ9toqqd0ehaevremo7Z5bzVXlU-MlGpAGBEqyh7fBUMlRQTlEzWUZHUENJTkUyTFVaS09QT0o3Qy4u&amp;route=shorturl">Registrace je otevřena</a> – kapacita je již z poloviny zaplněna, proto doporučujeme rezervovat si místo co nejdříve. Pokud jste se již registrovali, považujte výzvu k registraci za bezpředmětnou. (registrace možná do pondělí 13. 4. 2026 nebo do vyčerpání kapacity)</li><li>Pro připojení online je možná do 20. 4. 2026 a není omezená - odkaz <a target="_blank" rel="noopener noreferrer" href="https://forms.office.com/pages/responsepage.aspx?id=LXJ9toqqd0ehaevremo7Z5bzVXlU-MlGpAGBEqyh7fBUMlRQTlEzWUZHUENJTkUyTFVaS09QT0o3Qy4u&amp;route=shorturl">ZDE</a></li><li>Účast na online webináři je bezplatná.</li><li>Přístup k záznamům přednášek a materiálů bude zajištěn všem účastníkům.</li></ul></blockquote><h3>Program</h3><h5>8:30 Káva na uvítanou, drobné občerstvení a registrace</h5><h5>9:00 Úvod</h5><ul><li>Jaroslav Pól (Thermo Fisher Scientific)</li></ul><h5>9:10 Prediktivní mikrobiologické modely</h5><ul><li>Ing. Naděžda Kulišťáková Cahlíková, Ph.D. (Eurofins)<ul><li>působí jako vedoucí oddělení auditů a expert na bezpečnost potravin ve společnosti Eurofins. Dlouhodobě se věnuje HACCP, GFSI standardům a auditům v potravinářství a podílí se také na odborném vzdělávání v oboru.</li></ul></li></ul><h5>9:40 Molekulární vs. kultivační metody v mikrobiologii potravin</h5><ul><li>Patrik Dočkal (Thermo Fisher Scientific)<ul><li>působí ve společnosti Thermo Fisher Diagnostics CZ a má více než 8 let zkušeností v oblasti mikrobiologie a molekulární diagnostiky. Zaměřuje se na klasickou mikrobiologickou diagnostiku a využití PCR metod v potravinářství.</li></ul></li></ul><h5>10:10 Přístup Státní veterinární správy k nové legislativě pro vyšetřování Listeria monocytogenes</h5><ul><li>Mgr. Michaela Zlámalová (Státní veterinární správa)<ul><li>pracuje jako odborný rada v oblasti bezpečnosti potravin a mikrobiologických rizik. Specializuje se na aplikaci mikrobiologických kritérií dle legislativy EU, včetně problematiky Listeria monocytogenes.</li></ul></li></ul><h5>10:40 Přestávka na kávu a občerstvení</h5><h5>11:10 Praktické zkušenosti s testováním listerie ve výrobě</h5><ul><li>RNDr. Hana Bulawová (Státní veterinární ústav Jihlava)<ul><li>působí ve Státním veterinárním ústavu v Jihlavě v oblasti hygieny potravin. Má více než 30 let praxe a je vedoucí národní referenční laboratoře pro Listeria monocytogenes. Ve své odborné činnosti se dlouhodobě věnuje mikrobiologii potravin a laboratorní diagnostice.</li></ul></li></ul><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Fisher_Scientific_Prednasejici_seminar_Trendy_mikrobiologickeho_testovani_listerii_v_potravinarstvi_2026_Nadezda_Kulistakova_Cahlikova_Michaela_Zlamalova_Hana_Bulawova_Lenka_Bartosova_Jan_Pivonka_Patrik_Dockal_24262bff53.jpg" alt="Thermo Fisher Scientific: Přednášející seminář Trendy mikrobiologického testování listerií v potravinářství 2026: Naděžda Kulišťáková Cahlíková, Michaela Zlámalová, Hana Bulawová, Lenka Bartošová, Jan Pivoňka, Patrik Dočkal" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Fisher_Scientific_Prednasejici_seminar_Trendy_mikrobiologickeho_testovani_listerii_v_potravinarstvi_2026_Nadezda_Kulistakova_Cahlikova_Michaela_Zlamalova_Hana_Bulawova_Lenka_Bartosova_Jan_Pivonka_Patrik_Dockal_24262bff53.jpg 245w," sizes="100vw" width="1356" height="271"><h5>11:40 Diskuse u kulatého stolu</h5><ul><li>moderuje Ing. Jan Pivoňka Ph.D. (Česká technologická platforma pro potraviny)<ul><li>působí v akademické sféře na VŠCHT Praha, kde se zaměřuje na oblast kvality a bezpečnosti potravin. Má dlouholeté zkušenosti s řízením laboratoří a vedením odborných týmů. Dále působí v rámci České technologické platformy pro potraviny a jako ředitel Potravinářské komory pro kvalitu, vědu a inovace.</li></ul></li><li>Mgr. Lenka Bartošová, Ph.D. (Státní zemědělská a potravinářská inspekce)<ul><li>pracuje na ústředním inspektorátu Státní zemědělské a potravinářské inspekce v oddělení laboratoří, kde se zaměřuje na mikrobiologii potravin a související laboratorní problematiku. Podílí se na odborné činnosti v oblasti kontroly bezpečnosti potravin a laboratorního hodnocení.</li></ul></li><li>RNDr. Hana Bulawová (Státní veterinární ústav Jihlava) a Mgr. Michaela Zlámalová (Státní veterinární správa),&nbsp;</li></ul><h5>12:40 Závěr</h5><ul><li>Jaroslav Pól (Thermo Fisher Scientific)</li></ul><h5>12:50 Malé občerstvení</h5>&nbsp;Těšíme se na setkání s Vámi!S pozdravem,Váš mikrobiologický tým Thermo Fisher Diagnostics CZ<blockquote><h5>Informace ohledně semináře:&nbsp;</h5><ul><li>Jméno: Lenka Kohoutová</li><li>E-mail: <a href="mailto:lenka.kohoutova@thermofisher.com">lenka.kohoutova@thermofisher.com</a></li><li>Tel.: +420 778 746 065</li></ul></blockquote>

Pozvánka na odborný seminář Trendy mikrobiologického testování listerií v potravinářství 2026

Naše každoroční speciální akce na spotřební materiál* značky Agilent je opět tu! HAPPY WEEK proběhne od pondělí 13. 4. 2026 od 7:00 do pátku 17. 4. 2026 do 16:00.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Altium_Hppy_week_2026_0e2c89bc49.jpg" alt="Altium International: Happy Week 2026" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Altium_Hppy_week_2026_0e2c89bc49.jpg 245w," sizes="100vw" width="940" height="475"><blockquote>📅 Omezená platnost: Cenové nabídky na produkty Agilent platné během tohoto týdne mají omezenou platnost uvedenou přímo v jejich hlavičce.💻 Jak získat slevu:&nbsp;Objednávky posílejte na e-mailovou adresu objednavky.cz@altium.net, nezapomeňte na promo kód HPAT0426.</blockquote>Jste registrovaní v našem e‑shopu? Pak po zadání promo kódu HPAT0426 v košíku získáte výjimečnou slevu. Promo kód bude aktivní po celou dobu trvání akce – od 13. 4. do 17. 4. do 16:00.* Upozornění: Sleva se nevztahuje na roční objednávky, ekonomická balení vialek, víček a stříkačkových filtrů, reagencie pro molekulární biologii, produkt Prozyme, servisní díly a kolony na zakázku. Slevu nelze kombinovat s jinými akcemi a slevami (např. s poinstalační slevou).

Altium Happy Week - 35% sleva na produkty spotřebního materiálu Agilent

Analytické laboratoře dnes očekávají od svých dodavatelů/partnerů komplexní řešení, které zahrnuje nejen samotnou přístrojovou techniku, ale také odpovídající aplikační podporu. V oblasti kapalinové chromatografie jsme dlouhodobě schopni nabídnout široké spektrum instrumentace a odborného know-how, přesto zde až doposud chyběl jeden důležitý dílek celé skládačky – iontová chromatografie.Abychom našim zákazníkům mohli tyto požadavky pokrýt skutečně v plném rozsahu, rozšířili jsme portfolio Altium o <a target="_blank" rel="noopener noreferrer" href="https://lcms.cz/products?category=38&amp;distributorItems=37">iontovou chromatografii značky SHINE</a>. Tímto krokem reagujeme nejen na potřeby rutinních laboratoří, ale i na náročné aplikace, které vyžadují vysokou technickou úroveň, flexibilitu a spolehlivost.Iontová chromatografie nachází nejčastěji uplatnění v laboratořích, které se zabývají kvalitou vod — pitných, povrchových i odpadních. Je preferovanou metodou pro stanovení aniontů a kationtů díky nízkým detekčním limitům, vysoké přesnosti a reprodukovatelnosti, což je klíčové pro splnění legislativních norem i pro efektivní řízení procesů úpravy vod. Metoda se však osvědčuje i v jiných oblastech, například při kontrole surovin a výrobních procesů v chemickém průmyslu, ve farmaceutickém a potravinářském sektoru nebo při environmentálním monitoringu. Pro všechny tyto aplikační potřeby máme se značkou SHINE připravené komplexní řešení v podobě rozmanitého portfolia iontových chromatografů, které pokrývá jak rutinní analytické úlohy, tak pokročilejší technické požadavky moderních laboratoří.Portfolio iontové chromatografie SHINE je ve skutečnosti velmi široké a zahrnuje řadu konfigurací a přístrojových variant. Pro účely tohoto článku jsme však vybrali konkrétní systémy, o kterých jsme přesvědčeni, že právě tyto přístroje mají největší potenciál najít své uplatnění v běžné laboratorní praxi a dokážou nejlépe odpovědět na reálné požadavky analytických laboratoří.<a target="_blank" rel="noopener noreferrer" href="https://lcms.cz/products/2259">CIC-D120+</a> je základní model z řady SHINE iontových chromatografů. Jde o stabilní a spolehlivý systém, který je určený pro běžné iontové analýzy. Přístroj je vybaven kvalitním autosamplerem a neustále sleduje své klíčové části celé sestavy, aby výsledky byly co nejvíce opakovatelné a provoz co nejméně náchylný k neočekávaným výpadkům. Díky jednoduchému provozu a nižší náročnosti na údržbu je CIC-D120+ vhodnou volbou pro laboratoře hledající spolehlivý chromatograf pro každodenní použití.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Altium_Obr_1_Iontovy_chromatograf_SHINE_CIC_D120_41e498cebb.jpg" alt="Altium International: Obr. 1 Iontový chromatograf SHINE CIC-D120+" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Altium_Obr_1_Iontovy_chromatograf_SHINE_CIC_D120_41e498cebb.jpg 245w," sizes="100vw" width="1600" height="900"><a target="_blank" rel="noopener noreferrer" href="https://lcms.cz/products/2258">CIC-D160+</a> je technologicky pokročilejší model z řady SHINE, který je vybaven generátorem eluentu přímo v přístroji. Díky tomu si systém sám připravuje potřebnou mobilní fázi, což odstraňuje ruční manipulaci s reagenciemi a snižuje riziko chyb při přípravě analýzy. Tento koncept ocení zejména pracoviště, kde se často mění analytické metody nebo kde je kladen důraz na dlouhodobou stabilitu výsledků.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Altium_International_Obr_2_Iontovy_chromatograf_SHINE_CIC_D160_s_generatorem_eluentu_3caa1c3826.jpg" alt="Altium International: Obr. 2 Iontový chromatograf SHINE CIC-D160+ s generátorem eluentu." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Altium_International_Obr_2_Iontovy_chromatograf_SHINE_CIC_D160_s_generatorem_eluentu_3caa1c3826.jpg 174w," sizes="100vw" width="1233" height="1105"><a target="_blank" rel="noopener noreferrer" href="https://lcms.cz/products/2256">CIC-D300+</a> představuje pokročilý duální iontový chromatograf, který je navržen pro současnou a plně nezávislou analýzu aniontů a kationtů. Každý kanál pracuje autonomně, bez vzájemného ovlivnění, což umožňuje paralelní provoz dvou metod a výrazně zvyšuje analytickou kapacitu laboratoře. Tento přístup je přínosný zejména v provozech s vysokým počtem vzorků nebo tam, kde je požadována flexibilita při kombinaci různých typů analýz. Systém je vybaven integrovaným generátorem eluentu, který zajišťuje stabilní a reprodukovatelnou přípravu mobilní fáze bez nutnosti manuální manipulace s reagenciemi. V kombinaci s elektrolytickou supresí přispívá toto řešení k nízkému šumu základní linie a vysoké citlivosti detekce, což je důležité zejména při stanovení stopových koncentrací iontů.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Altium_International_Obr_3_Dualni_iontovy_chromatograf_SHINE_CIC_D300_8edd2a84b6.jpg" alt="Altium International: Obr. 3 Duální iontový chromatograf SHINE CIC-D300+" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Altium_International_Obr_3_Dualni_iontovy_chromatograf_SHINE_CIC_D300_8edd2a84b6.jpg 245w," sizes="100vw" width="2000" height="1127"> <a target="_blank" rel="noopener noreferrer" href="https://lcms.cz/products/2255">CIC-D3200</a> je automatizovaný spalovací IC systém, který je navržen pro stanovení celkového obsahu halogenů, zejména celkového organicky vázaného fluoru (AOF). Právě tento parametr získává v souvislosti s regulací PFAS látek stále větší význam, protože poskytuje celkový přehled o fluorované zátěži vzorku bez ohledu na konkrétní chemickou strukturu jednotlivých sloučenin. Systém kombinuje řízené vysokoteplotní spalování s následnou iontovou chromatografií a umožňuje plně automatizovaný a reprodukovatelný postup i pro náročné pevné matrice.Díky programovatelné spalovací peci s vícestupňovým ohřevem, automatickému dávkování vzorků a možnosti přímého propojení s IC systémy SHINE představuje CIC-D3200 efektivní řešení pro laboratoře, které se zabývají PFAS screeningem,AOF analýzami a environmentálním monitoringem v souladu s aktuálními i připravovanými legislativními požadavky.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Altium_Obr_4_Automatizovany_spalovaci_IC_system_SHINE_CIC_D3200_8fefd16a74.jpg" alt="Altium International: Obr. 4 Automatizovaný spalovací IC systém SHINE CIC-D3200." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Altium_Obr_4_Automatizovany_spalovaci_IC_system_SHINE_CIC_D3200_8fefd16a74.jpg 245w," sizes="100vw" width="1600" height="630"> Kromě samotných přístrojů nabízí SHINE také vlastní portfolio iontově-chromatografických kolon a supresorů, které jsou navrženy tak, aby byly kompatibilní i s dalšími zavedenými IC systémy na trhu. Laboratořím to dává větší flexibilitu při volbě spotřebního materiálu a zároveň usnadňuje případný přechod z jiných platforem. Právě zde hrají důležitou roli také aplikační listy SHINE, které slouží jako praktická metodická opora při nastavování separací, volbě vhodné kolony nebo optimalizaci podmínek na novém systému.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Altium_Obr_5_Kolony_a_supresory_SHINE_407a9fa4ce.jpg" alt="Altium International: Obr. 5 Kolony a supresory SHINE." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Altium_Obr_5_Kolony_a_supresory_SHINE_407a9fa4ce.jpg 245w," sizes="100vw" width="1043" height="471"><a target="_blank" rel="noopener noreferrer" href="https://lcms.cz/products?category=48&amp;distributorItems=37&amp;search=SHINE">Kolony a supresory SHINE</a> přitom představují ekonomicky velmi zajímavou alternativu ke spotřebnímu materiálu tradičních výrobců, aniž by bylo nutné slevovat z požadavků na separační výkon, stabilitu nebo reprodukovatelnost měření. Pro řadu laboratoří tak mohou být nejen technickým, ale i provozně efektivním řešením.Rozšířením našeho portfolia o iontovou chromatografii SHINE tak reagujeme na současné potřeby analytických laboratoří, které stále častěji hledají partnera schopného nabídnout ucelené řešení zahrnující přístrojovou techniku, spotřební materiál i aplikační podporu.Naším cílem je stát se pro Vás právě takovým partnerem – tedy firmou, která propojuje odpovídající technologii s odborným zázemím a praktickými zkušenostmi z laboratorní praxe.<blockquote><h5>Pro další informace kontaktujte:&nbsp;</h5><ul><li>Jan Kovář - Produktový specialista (HPLC, LC/MSD)</li><li>Tel.: 607 081 917</li><li>E-mail: jan.kovar@altium.net&nbsp;</li></ul></blockquote>

Nová kapitola iontové chromatografie SHINE v portfoliu Altium

Potraviny

Článek

Produkt

Video

Nejbližší akce

Unikátní společnost, která se věnuje vědě a pomáhá našim zákazníkům zvyšovat produktivitu a získavat výsledky rychleji. Prostřednictvím našich předních značek - Thermo Scientific, Applied Biosystems, Invitrogen, Fisher Scientific a Unity Lab Services. 

Thermo Fisher Scientific

Je autorizovaným distributorem společnosti Agilent Technologies pro Českou republiku v oblastech chromatografie (GC, HPLC, UHPLC, kapilární elektroforéza) a hmotnostní spektrometrie (GC/MS, LC/MS, CE/MS), disolučních aparátů, molekulární (UV-Vis, UV-Vis-NIR, fluorescence, FTIR analyzátory a mikroskopy) a atomové spektroskopie (ICP-OES, ICP-MS, AAS), a v neposlední řadě také v oblasti molekulární biologie a genomiky (analýza nukleových kyselin a proteinů, microarray skenery a skla, PCR & RT-PCR, qPCR, řešení pro NGS, reagencie pro mutagenezi a klonování, sondy FISH a další).

Altium International

Pittcon

Phenomenex

SelectScience

SCIEX

Evosep Biosystems

Waters Corporation

Supramolecular structures formed from bioactive and responsive polymers can be used as smart carrier systems for enzymes or drugs. Given the inherent heterogeneity of these complex nanostructures, their characterization is a significant challenge.
In this exclusive webinar, join experts Dr. Susanne Boye and Dr. Robert Mildner, to learn more about asymmetric-flow field-flow fractionation (AF4), a versatile, state-of-the-art separation technique for simplifying sample matrices, enabling subsequent microstructural analysis. Coupled AF4 with multiple online detectors (multi-angle light scattering, dynamic light scattering, differential refractometer, UV/Vis and differential viscometer) provides rich data for multidimensional characterization and correlation.
The MD-AF4 analytical platform supports in-depth physical and chemical understanding of natural and synthetic macromolecules, their self-assemblies and bioconjugates. Dr. Boye and Dr. Mildner will discuss MD-AF4 and its applications to polymer-protein hybrids, exosome-polymer-hybrids, stimuli-responsive polymeric vesicles and single chain nanoparticles.
Key learning objectives
<ul>
<li>Learn more about the background and instrumentation for separation and analysis by MD-AF4
</li>
<li>Find out how MD-AF4 determines physical and chemical parameters of natural and synthetic macromolecules
</li>
<li>Discover how MD-AF4 is used to analyze self-assemblies and bioconjugates
</li>
</ul>
Who should attend?
<ul>
<li>Chemists and nanoengineers requiring in-depth characterization of complex polymeric and nanoparticle systems
</li>
<li>Drug-development scientists exploring analytical instrumentation for nano-drug delivery vehicles
</li>
</ul>
<blockquote>
Presenter: Susanne Boye, PhD (Center for Macromolecular Structure Analysis)
</blockquote>
<blockquote>
Dr. Susanne Boye is the leader of the Field-flow Fractionation team of the Polymer Separation Group, the leader of the Thermal Analysis Lab and deputy head of the Center for Macromolecular Structure Analysis of the Leibniz Institute of Polymer Research Dresden (IPF), Germany. She graduated in biochemical engineering and obtained a PhD in the polymer separation field at the Technical University Dresden and IPF. Dr. Boye is particularly interested in the conformation analysis of biomacromolecules and the physico-chemical characterization of polymer-protein conjugates, complex synthetic and natural (bio-) nanostructures and molecular interactions, with more than 60 publications in these fields.
</blockquote>
<blockquote>
Presenter: Robert Mildner, PhD (Waters | Wyatt Technology)
</blockquote>
<blockquote>
Dr. Robert Mildner is an Application Scientist at Wyatt Technology in Europe, where he is responsible for performing research projects and feasibility studies utilizing Wyatt´s unique instrumentation. His work includes testing of novel applications as well as the implementation of established methods for users of Wyatt instruments. He focuses on field-flow fractionation (FFF) and size-exclusion chromatography (SEC) coupled to multi-angle light scattering (MALS). Robert obtained his PhD from the University of Technology Braunschweig, Germany, in the field of macromolecular chemistry.
</blockquote>
<blockquote>
Presenter. Carrie Haslam (SelectScience)
</blockquote>
<blockquote>
Dr. Carrie Haslam is an Associate Editor at SelectScience, playing a key role in content production and specializing in Materials Science, Alzheimer’s disease and Clinical Diagnostics. Carrie completed a Ph.D. from The University of Plymouth, where she developed graphene-based biosensors for the early diagnosis of Alzheimer’s disease.
</blockquote>

Waters Corporation: Unraveling the complexity: Advanced analysis of polymeric nanostructures

Unraveling the complexity: Advanced analysis of polymeric nanostructures

Learn more about asymmetric-flow field-flow fractionation (AF4).

Advanced analysis of polymeric nanostructures

The identification and quantification of compounds in biological samples are commonly performed using a technique called reversed phase-HPLC- hyphenated to mass spectrometric detection (RP-HPLC-MS).
However, when authentic standards are not available, quantification becomes difficult due to the analyte-specific response of the detector, as the relative signal intensities in electrospray ionization-MS are dependent on ionization efficiency.
The choice of an appropriate standard is further limited by various parameters such as the chemical and physical properties of the analyte or the retention behavior.
Additionally, in lipid research, the analytes often lack chromophoric groups, which means that UV/vis detection is not feasible, or additional derivatization procedures become inevitable.
To overcome these challenges, a complementary quantification strategy called charged aerosol detection (CAD) is employed. CAD offers a consistent and uniform response for nearly all non-volatile substances, whilst ensuring both mass sensitivity and robustness.
In this webinar, quantification strategies without authentic standards based on HPLC-CAD will be showcased for determination of several lipid classes in complex sample matrices. Examples of these lipid classes include biosurfactants like rhamnolipids and liamocins, as well as membrane lipids such as phospholipids.
Learning points:
<ul>
<li>What makes charged aerosol detection so powerful
</li>
<li>What benefits it offers
</li>
<li>What applications are ideal for charged aerosol detection?
</li>
</ul>
Who should attend:
<ul>
<li>Laboratory managers
</li>
<li>Technology leaders
</li>
<li>Principal scientists
</li>
<li>Laboratory analyst
</li>
</ul>
<blockquote>
Presenter: Prof. Dr. Heiko Hayen (Professor, Institute of Inorganic and Analytical Chemistry, University of Münster)
</blockquote>
<blockquote>
Heiko Hayen is professor for Analytical Chemistry at the University of Münster since 2014. He studied Food Chemistry and obtained his PhD in Analytical Chemistry at the University of Twente (Enschede, The Netherlands) in 2003.
</blockquote>
<blockquote>
After a postdoctoral research stay at the Institute for Marine Biosciences (National Research Council of Canada, Halifax, Nova Scotia, Canada), he moved to the Department of Bioanalytics, Leibniz-Institut für Analytische Wissenschaften – ISAS – e.V., Dortmund.
</blockquote>
<blockquote>
From 2010 to 2014 he held a professorship in Food Chemistry at the Faculty of Mathematics and Natural Sciences, University of Wuppertal.
</blockquote>
<blockquote>
His current research interests include the development of hyphenated mass spectrometric methods for the investigation of metabolites and lipids, like phospholipids and glycolipids, using HPLC-MS, SFC-MS and capillary IC-MS.
</blockquote>
<blockquote>
Presenter: Chris Tuczemskyi (Moderator, Product Marketing Manager, Thermo Fisher Scientific)
</blockquote>
<blockquote>
Chris Tuczemskyi is a chromatography specialist at Thermo Fisher Scientific, based in Cambridge, UK. After spending a number of years building up his experience with chromatography instruments in a water testing laboratory, he joined Thermo Fisher Scientific in 2014 as a chromatography service engineer for Unity Lab Services. Here he developed his passion for supporting customers using HPLC and in 2018 moved into the application specialist team. More recently, in 2022 he made the move to Product Marketing to help ensure we meet and exceed our customers expectation. In 2009, Chris graduated from the University of Essex in Biochemistry (Bsc Hons).
</blockquote>

Thermo Scientific: Absolute quantification of lipids in complex mixtures by HPLC without authentic standards

Absolute quantification of lipids in complex mixtures by HPLC without authentic standards

Quantification strategies without authentic standards based on HPLC-CAD will be showcased for determination of several lipid classes in complex sample matrices.

Absolute quantification of lipids

Immunopeptidomics is an emerging field that combines proteomics and immunology to study the complex repertoire of peptides presented by major histocompatibility complex (MHC) molecules on the cell surface.
These MHC-bound peptides, known as immunopeptidomes, play crucial roles in immune recognition and activation, influencing various physiological and pathological processes such as immune surveillance, infectious diseases, autoimmunity, and cancer.
Join our webinar to explore recent advancements, challenges, and applications in immunopeptidomics. Discover how Evosep One accelerates discoveries, and support the understanding of immune responses and diseases.
<blockquote>
Presenter: Anthony Purcell (Professor, Purcell Lab, Monsah University)
</blockquote>
<blockquote>
Presenter: Nicolai Bache (Head of Applications at Evosep)
</blockquote>

Advancing Immunopeptidomics

Recent advancements, challenges, and applications in immunopeptidomics.

<h5>Solving Problems that Matter: Risk Mitigation in the Pharma QC Laboratory</h5>
Expert Insights 3-Part Webinar Series: Risk Assessment, Control Strategies, and Intuitive Innovation to Improve Data Quality, Data Integrity and Lab Productivity. 
Pharma QC labs are facing increasing pressure on the cost of quality while maintaining compliance and assuring patient safety. From the harmonization of USP &lt;621&gt; to Empower™ workflows supporting data integrity to improving method transfer outcomes, you will learn from subject matter experts how to reduce errors and mitigate risk for reproducible data and enhanced productivity. 
Who should attend
<ul>
<li>Pharma QC Lab directors, managers and senior scientists with a drive to reduce errors, improve lab productivity and enhance data quality &amp; integrity.</li>
</ul>
<h3>PART 3 l Creating Efficiency in Your Routine Workflow with Simple Automation Steps in Empower</h3>
<ul>
<li>Wednesday, August 30th, 11:30-12:30 ET</li>
</ul>
According to the PIC/S guidance, complex or open-ended processes that lead to subjective interpretation can result in an increase in data failures. One way to reduce this risk is with a simplified, well-defined process. Empower software enables you with tools to create structure in your chromatographic processes and workflow.
In this presentation we will define a chromatographic workflow with Empower software to support data integrity goals - starting with method development, method validation, and routine usage to data acquisition, data processing, reporting results, and using control charts to track and trend data. This presentation will also introduce new features coming to Empower 3.8.0 such as safeguards to prevent common errors, enhanced column tracking &amp; history and more detailed audit trails.
<blockquote>
Presenter: Neil Lander (Principal Product Manager - Informatics Group, Waters Corporation)
</blockquote>
<blockquote>
Neil has worked for Waters Corporation since 1994 and has held a variety of positions including Technical Support Specialist, Technical Trainer, Manager Customer Education and currently, Principal Marketing Manager in Waters in the Informatics group. Neil provides internal support for Empower CDS software and is focused on developing laboratory software solutions that help organizations achieve their scientific and operational objectives. Prior to joining Waters Corporation, he was an analytical chemist where he gained experience in both the cosmetics and specialty chemical industries.
</blockquote>

Waters Corporation: Creating Efficiency in Your Routine Workflow with Simple Automation Steps in Empower

Creating Efficiency in Your Routine Workflow with Simple Automation Steps in Empower

Chromatographic workflow with Empower software to support data integrity goals.

Creating Efficiency in Your Routine Workflow

Immunopeptidomics is a field that combines proteomics and immunology to study the complex repertoire of peptides presented by major histocompatibility complex (MHC) molecules on the cell surface.
These MHC-bound peptides, known as immunopeptidomes, play crucial roles in immune recognition and activation, influencing various physiological and pathological processes such as immune surveillance, infectious diseases, autoimmunity, and cancer.
Join our webinar to explore recent advancements, challenges, and applications in immunopeptidomics. Discover how EvosepOne accelerates discoveries, and support the understanding of immune responses and diseases.
<h4>IMMUNOPEPTIDOMICS ON THE EVOSEP ONE – NEW LEVELS OF SAMPLE THROUGHPUT AND PRODUCTIVITY</h4>
Immunopeptidomics is the study of peptide antigens that are bound to and presented on the cell surface by molecules encoded by the Major Histocompatibility, a highly polymorphic region of the genome that encode molecules involved in immune responses. These peptides are derived from both intracellular and extracellular degradation of the parental proteins, generating a highly complex repertoire of peptide ligands, including peptides derived from pathogens, tissue specific and cancer specific antigens when relevant. In humans, human leukocyte antigen (HLA) class I and class II molecules are of particular interest for immunopeptidomic analysis. These molecules are encoded by several loci and constitute thousands different alleles that vary between individuals. Thus, immunopeptidomes are highly individualized and almost impossible to accurately predict. This predicates the empirical measurement of the complexity and diversity of immunopeptidomes using mass spectrometry. Due to the relatively small amounts of material available for analysis the use of nanoflow LC-MS for immunopeptidome analysis is critical. Here I explore the implementation of the high throughput EvoSEP one platform couples to a Bruker timsTOF Pro 2 for robust analysis of immunopeptidomes across a variety of tissues and cell lines. Using the Whisper 20SPD method data quality and depth is maintained whilst sample carryover is negligible allowing more productive use of instrument time; I highlight significant improvements in throughput with over 1500 immunopeptidomes characterised in just 3 months.
<blockquote>
Presenter: Anthony Purcell (Professor, Purcel Lab, Monsah University)
</blockquote>
<blockquote>
Presenter: Nicolai Bache (Head of Applications at Evosep)
</blockquote>
<h4>MAPPS: High throughput immunopeptidomics for the assessment of the immunogenic potential of protein biotherapeutics</h4>
Biologics, mostly monoclonal antibodies and recombinant proteins, are a class of drugs used to treat some particularly difficult conditions. These proteins, when recognized as non-self by the immune system, can elicit unwanted immunogenicity. One of the first steps in this cascade is the presentation of fragments of this protein by MHC complexes on antigen presenting cells, which might ultimately lead to generation of anti-drug antibodies (ADAs). These ADAs can lower the therapeutic efficiency and can lead to severe immunogenic effects. To bring safe biotherapeutics to the market it is critical to thoroughly assess the immunogenic profile of a biotherapeutic. MAPPS (MHC associated peptides proteomics) assays are the method of choice to define all potential immunogenic regions of a protein. ImmuneSpec, an advanced immunopeptidomics platform, offers MAPPS as a service. Here we show how the combination of high-throughput MHC peptide purification, fast LC using EvoSep, and high sensitive MS addresses these needs.
<blockquote>
Presenter: Kurt Boonen (Assistant Professor, Deparment of biomedical sciences, University of Antwerp)
</blockquote>
<blockquote>
Presenter: Nicolai Bache (Head of Applications at Evosep)
</blockquote>

Evosep: ADVANCING IMMUNOPEPTIDOMICS: LEVERAGING EVOSEP ONE FOR HIGH-THROUGHPUT ANALYSIS AND DISCOVERY

ADVANCING IMMUNOPEPTIDOMICS: LEVERAGING EVOSEP ONE FOR HIGH-THROUGHPUT ANALYSIS AND DISCOVERY

Immunopeptidomics: HIGH-THROUGHPUT ANALYSIS AND DISCOVERY

<h3>A New Era of Intuitive Simplicity</h3>
In March 2023 at Pittcon, Waters launched the Alliance iS HPLC System, designed specifically to help QC labs address their biggest challenges around error reduction, workflow efficiency, and compliance.
In this webinar, Debbie Francis, Principal Consulting Product Marketing Manager, QA/QC at Waters, will present some highlights from the product launch at this year’s Pittcon, and demonstrate a new, free tool that will help you to calculate approximately how much time and money the Alliance iS HPLC System could save your lab.
Agenda:
<ul>
<li>Overview of the new product from Fraser McLeod, Vice President of QA/QC at Waters, recorded live at Pittcon 2023
</li>
<li>Fireside chat with Fraser and Dr. Tina S. Morris, Executive Director of the American Association of Pharmaceutical Scientists (AAPS), recorded live at Pittcon 2023
</li>
<li>Demo of the ROI Calculator, a new tool that helps you see just how much time and money the Alliance iS HPLC System can save your lab.
</li>
</ul>
<blockquote>
Presenter: Debbie Francis (Principal Consulting Product Marketing Manager, Waters Corporation)
</blockquote>
<blockquote>
Debbie has worked for Waters since 2018 and has held multiple product marketing positions for Mass Spectrometry systems and is currently Principal Consulting Product Marketing Manager in QA/QC, focusing on next generation systems, where she has been leading the commercialization of the new era of simplicity in HPLC. Debbie began her career as a scientist in clinical laboratories, before moving into marketing, and prior to joining Waters held various regional and global marketing roles within the life science industry.
</blockquote>

Waters Corporation: Introducing the Alliance iS HPLC System

Introducing the Alliance iS HPLC System

How much time and money the Alliance iS HPLC System could save your lab.

In this session, explore the operation and latest developments of automated SPME for VOCs and SVOCs by headspace, direct immersion, and derivatization techniques.
Furthermore, discover how SPME has key applications for food, water, environmental and forensic samples for use in laboratories for GC-MS and LC-MS and direct MS analysis.
<blockquote>
Presenter: Hans-Joachim Huebschmann (Consultant, VP Sample Preparation, CTC Analytics)
</blockquote>

SelectScience: Solid phase microextraction – How does it work for my samples?

Solid phase microextraction – How does it work for my samples?

Explore the operation and latest developments of automated SPME for VOCs and SVOCs.

Solid phase microextraction–How does it work for my samples?

Key Learning Points:
<ul>
<li>Learn different sample preparation techniques, including solid support liquid extraction, Quechers and SPE
</li>
<li>How to develop a SPE method based on sample matrix and compound properties
</li>
<li>The challenge and workflow in the food Industry
</li>
</ul>
Who Should Attend:
<ul>
<li>Any beginner or intermediate scientists looking to learn more about sample preparation</li>
</ul>
<blockquote>
Presenter: Grace Guo (Senior Technical Specialist, Phenomenex)
</blockquote>
<blockquote>
Grace graduated from the Johns Hopkins University with a Master’s degree in Material Science and Engineering in 2014. In her graduate study, she developed a low-voltage organic phototransistor with an organic small molecule. After her graduation she moved from the east coast to west coast because she loves the all year long sunshine in South California.
</blockquote>
<blockquote>
She spent 3 years in a start-up company as Device Scientist doing single walled carbon nanotube separation and making thin film transistor with them. Most of her experience with Flash system are gained from there. In 2017, she joined Phenomenex as a Technical Specialist supporting globally, especially the Asia-Pacific area. Bilingual in Chinese and English makes it easy for her to communicate with customers in both US and China.
</blockquote>
<blockquote>
At Phenomenex she has more opportunity to have hands-on experience in HPLC, GC and SPE. Discussing the crazy troubleshooting cases with other technical members improves her chromatographic skills every day!
</blockquote>

Phenomenex: Sample Prep for Crude Extraction Removal & SPE Method and Development

Sample Prep for Crude Extraction Removal & SPE Method and Development

Learn different sample preparation techniques, including solid support liquid extraction, Quechers and SPE.

Sample Prep for Crude Extraction Removal & SPE Method

Were you unable to attend your local pharma day? If so not to worry!
We are delighted to host our popular pharma seminar day online. Following a series of events across Europe we are now bringing the talks to you virtually this September.
<h3>Overview</h3>
The analytical challenges within pharma are constantly changing and evolving. In many laboratories the requirements to deliver fast, accurate and robust results is always present and often the workload is growing too. The webinar will focus on analytical challenges and workflows in pharma analysis to help pharma labs succeed in these challenges.
On the day, you will be able to:
<ul>
<li>Hear about Waters’ latest innovation bringing ultimate simplicity to routine HPLC separations
</li>
<li>Learn about the benefits and tools for risk assessment and mitigation in your QC lab
</li>
<li>Understand the latest in AQbD requirements and how to apply them in your lab
</li>
<li>See the latest trace impurity quantification workflows, including nitrosamines analysis
</li>
</ul>
<h3>Agenda</h3>
<h5>Risk Assessment and Mitigation for Analytical Procedures</h5>
<ul>
<li>Andrea Gheduzzi (Principal Pharma Market Development Manager-EMEA, Waters)</li>
</ul>
<h5>Introducing a New Era on Intuitive Simplicity for Routine HPLC Alliance iS and System monitoring</h5>
<ul>
<li>Arjan Timmerman (Principal Pharma Market Development Manager – EMEA, Waters)</li>
</ul>
<h5>Nitrosamines and Beyond. Technologies for Optimizing Performance and Minimizing Risk in Trace Impurity Quantification</h5>
<ul>
<li>Antonia Wierzbicki (Principal Pharma Market Development Manager- EMEA, Waters)</li>
</ul>
<h5>Live Q&amp;A session</h5>
<blockquote>
Presenter: Andrea Gheduzzi (Southern Europe Pharma Market Dev. Manager, Waters Corporation
</blockquote>
<blockquote>
Andrea has spent more than 30 years in the chromatography field. Across his career he had various roles, service engineer, chromatography lab position, and technical application support manager. He has mainly been dealing with pharma accounts, also supporting LC method development activities using DoE/QbD approaches. In his role as Pharma Business Development Manager at Waters he has further expanded his expertise in AQbD and related applications.
</blockquote>
<blockquote>
Presenter: Arjan Timmerman (Pharma Market Development Manager EMEA, Waters Corporation)
</blockquote>
<blockquote>
Arjan is an experienced business development manager with a demonstrated history of working in regulated pharmaceutical industry. He holds a BSc in analytical chemistry and is skilled in life sciences, method development &amp; validation, laboratory informatics, compliance and data integrity.
</blockquote>
Within Waters Europe, he is a business development manager in core markets focusing on compliance and regulatory challenges (e.g. data integrity for laboratories), impurity analyses and recently on extractables &amp; leachables.
<blockquote>
Presenter: Antonia Wierzbicki (Pharma Market Devlopment Manager EMEA, Waters Corporation)
</blockquote>
<blockquote>
Antonia Wierzbicki is a marketing manager at Waters working in EMEA. Antonia has BSc in Pharmaceutical Science and a MSc in Cancer Pharmacology. Following several years working as an analytical chemist in drug development roles within both academic labs and contract research organizations, Antonia has more recently spent time working with analytical chemists to provide solutions using cutting edge technologies to meet their needs and requirements, with a specific interest in ultra-sensitive quantitation of small molecules. Antonia is based in Cambridge UK and keen to connect with like-minded scientists in the field.
</blockquote>

Waters Corporation: Waters Virtual Pharma Day - Analytical Challenges and Workflows in Pharma Analysis

Waters Virtual Pharma Day - Analytical Challenges and Workflows in Pharma Analysis

We are delighted to host our popular pharma seminar day online. Following a series of events across Europe we are now bringing the talks to you virtually.

Analytical Challenges and Workflows in Pharma Analysis

Recent changes to EU recommendations and regulation of per- and polyfluoroalkyl substances (PFAS) compounds in food have resulted in a renewed focus on this area within food manufacturers and testing agencies.
A reliable and sensitive analytical method, appropriate and validated for routine use, is imperative for ensuring consumer safety, not only by meeting current enforced legislation, but also by addressing recommendations for very low limits of quantitation (LOQs) in different foodstuffs.
Nestlé recently developed and validated an LC-MS/MS method for analyzing 57 PFAS compounds at the ng/kg level using the SCIEX 7500 system in various matrices. In this extraordinary webinar, Nestlé scientists will present the findings and results of their analysis.
Please register to learn about:
<ul>
<li>The analytical challenges of achieving LOQs at the ng/kg level in food matrices</li>
<li>The development of a robust LC-MS/MS method</li>
<li>The challenges of the method for routine use</li>
</ul>
Speaker:
<blockquote>
Presenter: Xanthippe Theurillat (Nestlé Research Center, Switzerland)
</blockquote>
<blockquote>
Xanthippe Theurillat is an Analytical Chemist. In 2012, she joined the Official Food Control Laboratory in Lausanne, Switzerland, as a Scientific Expert in the contaminants section. In 2015, she joined Nestlé Research in Lausanne, Switzerland, as an Analytical Scientist in the Analytical Science Department. Here, she specializes in the field of food contaminants, with a specific focus on pesticides, polyphenols, process contaminants (including understanding them at the mechanistic level) and PFAS.
</blockquote>

SCIEX: Development and validation of a sensitive, routine LC-MS/MS method for PFAS in food samples using the SCIEX 7500 system

Development and validation of a sensitive, routine LC-MS/MS method for PFAS in food samples using the SCIEX 7500 system

Nestlé recently developed and validated an LC-MS/MS method for analyzing 57 PFAS compounds at the ng/kg level using the SCIEX 7500 system in various matrices.