Vážení zákazníci,přichází JARNÍ AKCE 2026, během které můžete využít zvýhodněné ceny na široký sortiment spotřebního materiálu pro vaši laboratoř.<h4>Nabízíme vše, co potřebujete pro každodenní provoz i náročné analýzy:</h4><ul><li>kolony pro HPLC, UHPLC, BioLC</li><li>kolony pro GC a IC</li><li>spotřební materiál pro přípravu vzorků</li><li>drobné laboratorní vybavení</li></ul>Kvalitní spotřební materiál je základem spolehlivých výsledků. Využijte proto tuto příležitost a doplňte své zásoby za výhodnějších podmínek.<blockquote>Akce je platná na území ČR od 1. 4. do 31. 5. 2026.Kontaktujte nás jednoduše na e-mailu: chromatografie@pragolab.cz.</blockquote><h4>−30 % HPLC kolony</h4><ul><li><a target="_blank" rel="noopener noreferrer" href="https://lcms.cz/products/423">Hypersil GOLD</a> — <a target="_blank" rel="noopener noreferrer" href="https://lcms.cz/products?category=48&amp;manufacturerItems=3&amp;search=accucore">Accucore</a> — <a target="_blank" rel="noopener noreferrer" href="https://lcms.cz/library?mainauthorItems=3&amp;search=Syncronis">Syncronis</a> — <a target="_blank" rel="noopener noreferrer" href="https://lcms.cz/library?mainauthorItems=3&amp;search=Hypercarb">Hypercarb</a></li></ul><h4>−20 % BioLC kolony a kolony pro speciální aplikace</h4><ul><li><a target="_blank" rel="noopener noreferrer" href="https://lcms.cz/library?mainauthorItems=3&amp;search=MabPac">MabPac</a> — <a target="_blank" rel="noopener noreferrer" href="https://lcms.cz/library?mainauthorItems=3&amp;search=ProPac">ProPac</a> — <a target="_blank" rel="noopener noreferrer" href="https://lcms.cz/library?mainauthorItems=3&amp;search=PepMap">PepMap</a> — <a target="_blank" rel="noopener noreferrer" href="https://lcms.cz/library?mainauthorItems=3&amp;search=EasySpray">EasySpray</a> — <a target="_blank" rel="noopener noreferrer" href="https://lcms.cz/library?mainauthorItems=3&amp;search=Acclaim">Acclaim</a></li></ul><h4>−20 % GC kolony</h4><ul><li><a target="_blank" rel="noopener noreferrer" href="https://gcms.cz/products?category=7&amp;distributorItems=42&amp;search=TraceGOLD">TraceGOLD</a> — <a target="_blank" rel="noopener noreferrer" href="https://gcms.cz/products?category=7&amp;distributorItems=42&amp;search=Trace">Trace GC</a> — <a target="_blank" rel="noopener noreferrer" href="https://gcms.cz/products?category=7&amp;distributorItems=42&amp;search=TracePLOT">Trace PLOT</a></li></ul><h4>−25 % IC kolony a spotřební materiál</h4><ul><li><a target="_blank" rel="noopener noreferrer" href="https://lcms.cz/library?instrumentationItems=28-34&amp;mainauthorItems=3&amp;search=columns">Kolony</a> — <a target="_blank" rel="noopener noreferrer" href="https://lcms.cz/library?instrumentationItems=28&amp;mainauthorItems=3&amp;search=EGC">EGC</a> — supresory — vialky</li></ul><h4>−25 % <a target="_blank" rel="noopener noreferrer" href="https://gcms.cz/labrulez-bucket-strapi-h3hsga3/Pragolab_vialka_f386946736/Pragolab_vialka_.pdf">Vialky Pragolab</a></h4><ul><li>Vialky — septa — kity</li></ul><h3>Přehled nejnovější literatury z oblasti spotřebního matriálu od Thermo Scientific v knihovně <a target="_blank" rel="noopener noreferrer" href="https://lcms.cz/library?from=2025&amp;instrumentationItems=20&amp;manufacturerItems=2&amp;to=2026">LabRulezLCMS</a></h3><ul><li>Instrument and LC column migration for the purification and analysis of synthetic oligonucleotides (Aplikace | 2025)</li><li>Evolution of Ion-Exchange columns for biologics characterization (Prezentace | 2025)</li><li>Advancing Low flow LC/MS for single cell proteomics with variable flow and 50 cm microfabricated pillar array columns (Prezentace | 2025)</li><li>Wide-ranging polynucleotide separation capabilities using Reversed Phase particles with variable pore geometry (Postery | 2025)</li><li>Evaluation of batch-to-batch consistency of reversed phase HPLC columns for long-term method validation (Postery | 2025)</li><li>Efficient tandem capillary flow LC-MS with short μPAC columns and a single ionization source (Postery | 2025)</li><li>At the intersection between chromatographic performance, ESI efficiency and instrument productivity: nano to capillary flow LC/MS on long μPAC Columns (Postery | 2025)</li><li>Achieving consistent SEC performance through the use of 3 μm, 550 Å monodisperse media in novel bioinert column hardware (Postery | 2025)</li><li>Improved accuracy and identification in label-free quantitative proteomics with the OptiSpray Ion Source and separation cartridge with integrated replaceable emitters (Postery | 2025)</li><li>Accucore columns Resolve all your impurities without feeling the pressure (Ostatní | 2025)</li><li>SureSTART Vial Quick Select Guide (Ostatní | 2025)</li><li>Sensitive cationic lipids impurities analysis with quantitation by charged aerosol detection and simultaneous mass confirmation by MS (Aplikace | 2025)</li><li>Thermo Scientific Viper TQ UHPLC Fittings (Brožury a specifikace | 2025)</li><li>HPLC vials and well plates - Every drop counts (Brožury a specifikace | 2025)</li></ul><h3>Vybrané nejnovější <a target="_blank" rel="noopener noreferrer" href="https://lcms.cz/webinars?companyId=42">webináře</a> Thermo Scientific z oblasti spotřebního materiálu</h3><h5>1. Mastering Single Cell Proteomics: Daily Excellence with μPAC Neo Plus Trap-and-Elute Workflow</h5><ul><li><a target="_blank" rel="noopener noreferrer" href="https://lcms.cz/webinar/5789">ZÁZNAM</a> | Proběhlo Út, 27.1.2026</li></ul>Zjistěte, jak dosáhnout robustní, vysoce citlivé proteomiky jednotlivých buněk pomocí systému μPAC Neo Plus trap-and-elute LC-MS se systémy Vanquish Neo a Orbitrap.<h5>2. Monodisperse inert HPLC columns for large molecule analysis in biopharma</h5><ul><li><a target="_blank" rel="noopener noreferrer" href="https://lcms.cz/webinar/5729">ZÁZNAM</a> | Proběhlo Út, 9.12.2025</li></ul>Připojte se k nám na zajímavém webináři o pokročilých chromatografických metodách pro analýzu velkých biomolekul.<h5>3. Reduce analyte loss in LC workflows: The role of vial and surface chemistry</h5><ul><li><a target="_blank" rel="noopener noreferrer" href="https://lcms.cz/webinar/5675">ZÁZNAM</a> | Proběhlo Po, 17.11.2025</li></ul>Objevte strategie pro zvýšení výtěžnosti vzorků proteinů a peptidů. Zjistěte, jak materiály vialek a nespecifická vazba ovlivňují výsledky LC, a získejte tipy pro zlepšení reprodukovatelnosti testů.

Pragolab JARNÍ SLEVY 2026

<h4>Využijte jedinečné příležitosti a vyzkoušejte si vybrané GC / LC kolony a další spotřební materiál ZDARMA!</h4><blockquote><ul><li>promo kód: 2555</li><li>nabídka platná do: 7. 8. 2026</li></ul></blockquote><h5>Na co se akce vztahuje:</h5><ul><li>kompletní portfolio GC kolon – včetně nejnovějších <a target="_blank" rel="noopener noreferrer" href="https://gcms.cz/labrulez-bucket-strapi-h3hsga3/br_5q_gc_column_campaign_5994_7596en_agilent_baca38e505.pdf">5Q GCMS</a></li><li>většinu HPLC kolon - včetně nejnovějších ultra-inertních kolon <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/labrulez-bucket-strapi-h3hsga3/br_altura_hplc_columns_ultra_inert_technology_5994_8687en_agilent_517a6c36a7.pdf">Altura</a></li><li>vybraný spotřební materiál pro přípravu vzorků - včetně nejnovějších <a target="_blank" rel="noopener noreferrer" href="https://lcms.cz/article/5711">SPE kolonek PFAS WAX</a> s duální fází</li><li>a některé produkty Crosslab a OneNote – včetně <a target="_blank" rel="noopener noreferrer" href="https://lcms.cz/labrulez-bucket-strapi-h3hsga3/flyer_quick_connect_fittings_infinitylab_5991_5164_EN_agilent_0d67eecd72/flyer-quick-connect-fittings-infinitylab-5991-5164EN_agilent.pdf">Quick Connect Agilent InfinityLab Quick Connect Fittings</a> a <a target="_blank" rel="noopener noreferrer" href="https://lcms.cz/labrulez-bucket-strapi-h3hsga3/fl_infinitylab_quickturn_5994_7793en_agilent_819d965d19.pdf">Quick Turn fitinků</a> Agilent InfinityLab Quick Turn Fittings.</li></ul><blockquote><a target="_blank" rel="noopener noreferrer" href="https://www.hpst.cz/sites/default/files/download/2025-12/2555EligibleProductsList_25Sep25-komprimovan%C3%BD.pdf">Kompletní nabídka produktů v akci "Try and Buy"</a></blockquote>Lhůta 50 dnů na vyzkoušení bez platby předem. V případě nespokojenosti vrácení produktu zpět

Altium Akce Try and Buy na GC, HPLC kolony a jiný spotřební materiál

Tradiční postupy purifikace proteinů se v mnoha laboratořích stále opírají o ultracentrifugaci a dlouhé inkubační kroky. Tyto přístupy často zahrnují vícekrokové protokoly, prodloužené doby analýzy a použití specializovaného vybavení. V důsledku toho mohou být pracovní postupy složité, časově náročné a náchylné k variabilitě výsledků.Purifikace proteinů pomocí magnetických kuliček nabízí rychlejší, jednodušší a efektivnější alternativu, protože umožňuje selektivní zachycení a rychlou magnetickou separaci.<h3>Omezení konvenčních metod purifikace proteinů</h3>Ve standardních laboratorních postupech purifikace proteinů obvykle zahrnuje:<ul><li>Více pracovních kroků</li><li>Centrifugaci a ekvilibraci kolony</li><li>Závislost na specializovaném vybavení</li><li>Dlouhé doby zpracování</li></ul>Tyto faktory přinášejí několik výzev:<ul><li>Zvýšená složitost pracovních postupů</li><li>Variabilita mezi jednotlivými cykly, což snižuje reprodukovatelnost</li><li>Riziko ztráty vzorku při manipulaci, zejména u malých objemů vzorků nebo omezených množství cílových látek</li><li>Omezená kapacita kvůli manuální manipulaci</li></ul><h3>Princip purifikace pomocí magnetických kuliček</h3>Magnetické kuličky umožňují selektivní zachycení proteinů díky funkcionalizaci povrchu.Každá kulička je potažena streptavidinem, na který se váže biotinylovaný ligand. Tento ligand lze vybrat na základě cílového analytu a může zahrnovat:<ul><li>Protilátky</li><li>Aptamery</li><li>Fragmenty antigenu</li></ul>Tento krok poskytuje kuličkám specificitu potřebnou pro vazbu cílového analytu.<h3>Materiály a klíčové komponenty</h3><h4>Magnetické kuličky</h4><ul><li>Povrch potažený streptavidinem</li><li>Funkcionalizace biotinylovanými ligandy</li></ul><h4>Ligandy</h4><ul><li>Voleny dle cílového analytu</li><li>Navázané na kuličky před purifikací</li></ul><h3>Postup krok za krokem</h3><h4>1. Aktivace kuliček</h4>Navázání biotinylovaného ligandu na kuličky.<h4>2. Promývání</h4>Odstranění nečistot po funkcionalizaci.<h4>3. Inkubace se vzorkem</h4>Navázání cílového analytu na ligand.<h4>4. Magnetická separace</h4>Umístění vzorku na magnet:<ul><li>Magnetické kuličky (s navázaným analytem) se přitáhnou ke stěně nádoby</li><li>Kapalná fáze se oddělí</li></ul><h4>5. Promývání</h4>Promytí kuliček, zatímco zůstávají imobilizovány magnetickým polem, pro odstranění:<ul><li>Slabých interakcí</li><li>Nespecifických vazeb</li></ul><h4>6. Eluce</h4>Uvolnění analytu pomocí elučního roztoku.<h3>Následné aplikace</h3>Po eluci je purifikovaný vzorek připraven k další analýze, včetně:<ul><li>LC-MS</li><li>Western blot</li><li>ELISA</li><li>Testování aktivity</li></ul><h3>Výhody pracovních postupů založených na magnetických kuličkách</h3>Purifikace založená na magnetických kuličkách nabízí několik klíčových výhod:<h4>Rychlost a jednoduchost</h4><ul><li>Není nutná centrifugace</li><li>Není potřeba složité vybavení</li></ul><h4>Zlepšená reprodukovatelnost</h4><ul><li>Konzistentní magnetická separace</li><li>Snížená variabilita mezi jednotlivými cykly</li></ul><h4>Snížená ztráta vzorku</h4><ul><li>Méně kroků při manipulaci</li><li>Vhodné pro malé objemy vzorků nebo omezená množství cílových látek</li></ul><h4>Škálovatelnost a kapacita</h4><ul><li>Možnost automatizace</li><li>Podporuje formáty mikrodestiček:<ul><li>96-jamkové destičky</li><li>384-jamkové destičky</li></ul></li></ul><h3>Vlastnosti magnetických kuliček Biozen™</h3>Magnetické kuličky Biozen™ od společnosti Phenomenex zahrnují několik konstrukčních vlastností:<ul><li>Hydrofilní kopolymerový povrch<ul><li>Snižuje nespecifické hydrofobní interakce</li></ul></li><li>Biotinylovaný BSA spacer<ul><li>Působí jako spojovací článek ke streptavidinu</li><li>Pomáhá orientovat záchytné ligandy</li></ul></li><li>Monodisperzní ligandy<ul><li>Optimalizovaná vazebná kapacita</li></ul></li></ul>Tyto vlastnosti přispívají k:<ul><li>Snížení nespecifické vazby</li><li>Lepší reprodukovatelnosti</li><li>Čistším eluátům</li></ul><h3>Kdy použít magnetické kuličky</h3>Čištění pomocí magnetických kuliček je zvláště vhodné, když:<ul><li>Objemy vzorků jsou malé</li><li>Je vyžadována rychlá doba zpracování</li><li>Je omezené vybavení</li><li>Jsou potřebné pracovní postupy s vysokou propustností</li></ul><h3>Závěr</h3>Purifikace proteinů pomocí magnetických kuliček zjednodušuje tradiční pracovní postupy tím, že eliminuje odstřeďování a snižuje složitost. Díky selektivnímu zachycování a účinné magnetické separaci umožňuje rychlejší zpracování, lepší reprodukovatelnost a kompatibilitu s automatizovanými systémy s vysokou propustností.

Purifikace proteinů pomocí magnetických kuliček: Rychlejší a efektivnější pracovní postup

Akademie

Video

Článek

Produkt

Je autorizovaným distributorem společnosti Agilent Technologies pro Českou republiku v oblastech chromatografie (GC, HPLC, UHPLC, kapilární elektroforéza) a hmotnostní spektrometrie (GC/MS, LC/MS, CE/MS), disolučních aparátů, molekulární (UV-Vis, UV-Vis-NIR, fluorescence, FTIR analyzátory a mikroskopy) a atomové spektroskopie (ICP-OES, ICP-MS, AAS), a v neposlední řadě také v oblasti molekulární biologie a genomiky (analýza nukleových kyselin a proteinů, microarray skenery a skla, PCR & RT-PCR, qPCR, řešení pro NGS, reagencie pro mutagenezi a klonování, sondy FISH a další).

Altium International

Společnost Phenomenex je celosvětovým technologickým lídrem, který se zabývá vývojem nových řešení v oblasti analytické chemie, jež řeší požadavky analytiků na separace a purifikace v průmyslových, vládních a akademických laboratořích.

Phenomenex

Jsme jedním z lídrů na českém a slovenském trhu v oblasti laboratorních zařízení a svým zákazníkům přinášíme špičkové přístroje z oboru analytické chemie a fyzikálních měření více než 25 let.

Pragolab

The Analytical Scientist

Agilent Technologies

Wiley

Shimadzu Corporation

SCIEX

Waters Corporation

Size exclusion chromatography (SEC) is a noninteractive technique that separates solutes according to their molecular size in non-denaturing conditions. It is often used as the first step in isolation of a protein from a crude sample.
We will discuss the theory behind SEC, overview of mAbs, and characterization requirements; with a focus specifically on the effect of solute size and molecular weight, general rules for using SEC, column selection choices, important mobile phase considerations, and column care. We will explore method development pointers in the troubleshooting section.
<blockquote>
Presenter: Mohit Patel (Application Engineer, Agilent Technologies, Inc.)
</blockquote>
<blockquote>
Mohit Patel is part of the CSD Online AE Team. His primary focus is to support SMLC, Bio-Columns, and consumables.
</blockquote>
<blockquote>
Before joining Agilent, Mohit was an Assistant Professor of Chemistry at Temple University. Mohit developed his passion for science through his experiences as a faculty researcher and a mentor. Mohit actively taught, developed curriculum, and served as senior personnel, with a leadership position, on funded grants, mentored research projects, and co-coordinator of STEAM related outreach services.
</blockquote>
<blockquote>
Mohit has earned a Doctorate degree in Chemistry from Temple University in 2016.
</blockquote>

Agilent Technologies: SEC Overview and Method Development for Biomolecules

SEC Overview and Method Development for Biomolecules

We will discuss the theory behind SEC, overview of mAbs, and characterization requirements.

CHROMATOGRAPHY OF BIOSEPARATIONS 101 WEBINAR SERIES
This webinar series will cover the foundations of chromatography for the separation and analysis of peptides and proteins. Understanding the fundamentals of bioseparations will enable you to develop methods more efficiently. At the end of this series, you will be up to date on cutting edge principles and innovations surrounding bioseparations.
Who should attend? 
<ul>
<li>Those interested in a refresher on foundational principles and tips for bioseparations </li>
<li>Those revisiting which columns and mobile phases are optimal for which workflows </li>
<li>Those looking for an overview of industry advancements and new offerings</li>
</ul>
<blockquote>
Presenter: Bill Warren (Principal Product Manager – Chemistry Technology Center, Waters Corporation)
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<blockquote>
Bill received his Masters in Microbiology and Immunology from University of Louisville School of Medicine. In 1986, he joined Waters Corporation as a senior applications chemist involved with the research and development of HPLC, FPLC, and Capillary Electrophoresis applications for the analysis and purification of proteins, peptides, and nucleic acids. Following four years as a field based technical sales representative for Waters, Bill enjoyed a tenure as Manager, Core Product Evaluation Laboratory within the Waters Worldwide Marketing Organization. Bill currently is a Principal Bioseparation Columns Product Manager whose responsibilities involve assisting in the development and commercialization of innovative reagents and chromatography-based technologies for the separation, purification, and characterization of proteins and peptides.
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<blockquote>
HOST: Ravali Alagandula (Chemistry Products Marketing Manager, Americas Field Marketing, Waters Corporation)
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Ravali is a ChemistryProduct Marketing Manager within the Americas Field Marketing team at Waters. She holds a Ph. D. in Analytical Chemistry from Cleveland State University.She started her career as an LC applications scientist at Restek, developing LC-MS/MS and sample preparation methods in clinical, and life science markets. Most recently, Ravali was a Chemistry Account Manager at waters supporting key accounts and customers to promote chemistry consumable business in all market areas.
</blockquote>

Waters Corporation: CHROMATOGRAPHY OF BIOSEPARATIONS 101 WEBINAR SERIES

ION-EXCHANGE SEPARATIONS AND BEST PRACTICES FOR SALTY SEPARATIONS

This webinar series will cover the foundations of chromatography for the separation and analysis of peptides and proteins.

ION-EXCHANGE SEPARATIONS AND BEST PRACTICES

Key learning objectives
<ul>
<li>Solutions through
</li>
<li>Liquid Chromatography (LC) Column Technology
</li>
<li>Gas Chromatography (GC) Column Technology
</li>
<li>Pesticides
</li>
<li>Nutraceuticals
</li>
<li>Vitamins
</li>
</ul>
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Presenter: Darshan Engineer (Senior Business Development Manager)
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Phenomenex: Chromatographic Solution for Food, Nutraceuticals & Vitamin Analysis

Chromatographic Solution for Food, Nutraceuticals & Vitamin Analysis

Liquid Chromatography (LC) Column Technology & Gas Chromatography (GC) Column Technology...

Chromatographic Solution for Food, Nutraceuticals & Vitamins

Working with spectral and chromatographic data often results in noisy data. The good news is, there is a simple and efficient way to extract the signals from the noise, enabling a deeper and better understanding of processes and products.
If you are working on product or process development problems, you might need to utilise spectral and chromatographic data to understand and confirm that the process is performing optimally and generates the desired product. Frequently, we may summarise these data by using estimates based on peak height, position, and shape. But using these summaries inevitably causes us to lose some information about our process. This can reduce the insights we gain from our data analysis process and can negatively impact the quality of our decisions.
Spectral and related data are inherently noisy. This webinar will present a simple and efficient way of extracting the signals from the noise for a deeper, better understanding of your processes and products. If you are a scientist or engineer collecting spectral, chromatographic, or similar data and want to gain deeper insight into the trends and outcomes, this webinar is for you.
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Presenter: Florian Vogt (Systems Engineer JMP, JMP Statistical Discovery)
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Before joining SAS Institute, Florian worked as a process engineer in research and development at Südzucker AG, where he was involved in process optimization, product development and process evaluation. Florian Vogt holds a Master of Science in Biotechnology.
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Presenter: Emmanuel Romeu (Systems Engineer JMP, JMP Statistical Discovery)
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Emmanuel is a pre-sales consultant for the chemical industry. Prior to joining JMP, Emmanuel worked for 25 years at Beckman-Coulter &gt; Diagnostic where he successively worked in industrialization, R&amp;D in medical diagnostics and finally as a statistician. He graduated in biological engineering from the University of Clermont-Ferrand and in statistics from the University of Strasbourg.
</blockquote>

Unsplash/Mika Baumeister: Making better use of Spectral and Chromatographic Data in product and process development

Making better use of Spectral and Chromatographic Data in product and process development

This webinar will present a simple and efficient way of extracting the signals from the noise for a deeper, better understanding of your processes and products.

Making better use of Spectral and Chromatographic Data

While the world of R&amp;D is moving towards digitalization, the unique challenges of analytical data management continue to cause difficulties.
In our 2022 Analytical data management survey we learned and confirmed that…
<ul>
<li>Analytical data is diverse with multiple techniques, instrument vendors, and software
</li>
<li>It is stored and managed in many applications
</li>
<li>The majority still find it difficult to access and share
</li>
</ul>
Analytical data is ingrained in numerous research, development, and QA/QC workflows. While a small minority are starting to apply it for data science applications, most struggle to provide easy digital access for its most common uses.
Join our panel of experts as they discuss the results of the 2022 survey; the challenges related to analytical data that cross organizations and industries; and lessons learned through their own experience.
Webinar Learning Objectives:
<ul>
<li>How analytical data heterogeneity can be addressed</li>
<li>Attributes of effectively managed analytical data</li>
<li>Considerations for using analytical data for data science projects</li>
</ul>
<blockquote>
Presenter: Nichola Davies (Director Structural Chemistry UK, Oncology R&amp;D, Astra Zeneca)
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<blockquote>
Nichola Davies completed her PhD studies in physical organic chemistry at the University of Cambridge, utilising NMR spectroscopy to investigate positively cooperative binding and the tightening of non-covalent bonds. Nichola then joined Pfizer (Sandwich, UK) as an NMR spectroscopist supporting the medicinal chemistry department, and implemented new techniques for structure elucidation and the application of novel NMR methodologies to support medicinal chemistry design strategies.
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Having gained further experience in a wider range of analytical techniques, in 2014 she joined AstraZeneca (Cambridge, UK), as an NMR expert within the Oncology Chemistry R&amp;D Unit. Currently, as Director of the Structural Chemistry team, Nichola is delivering analytical techniques to support small molecule structural characterisation, purity and stability assessment, in addition to NMR free ligand conformational analysis and in-cell MS concentration assays.
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Presenter: Mark Kwasnik (Global Product Manager, Analytical Labs, Solvay)
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Mark Kwasnik is the Global Product Manager for the Analytical Labs at Solvay. In his role, Mark leverages digital tools in R&amp;I to reduce inefficiencies, increase responsiveness for customers. He works to accelerate the growth innovation pipeline by allowing the company’s scientists to access and use the thousands of data sets that are generated in Solvay’s R&amp;I labs.
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Prior to his transfer to Solvay&#39;s digital department, he worked as an Analytical Lab Manager for the North American R&amp;D Center and as the Global Digital Transformation Manager for the Specialty Polymer business unit.
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Mark received his B.S. in chemistry and forensic science from the University of Central Florida and a PhD in Analytical Chemistry, with a focus in BioAnalytical Mass Spectrometry, instrumentation development and informatics at the Georgia Institute of Technology.
</blockquote>
<blockquote>
Presenter: Graham A. McGibbon (Director, Strategic Partnerships, ACD/Labs)
</blockquote>
<blockquote>
Graham A. McGibbon is currently Manager of Scientific Solutions and Partnerships at Advanced Chemistry Development (ACD/Labs), a role which involves shaping innovative solutions with people in various industries, government organizations, academic institutions and enhancing relationships with organizations that supply analytical instrumentation and/or software.
</blockquote>
<blockquote>
Since obtaining a Ph.D. in Chemistry from McMaster University (Canada) Graham worked in drug discovery research at Boehringer Ingelheim conducting MS analyses of both small and large molecules; and researched modifications and interactions of bioactive small molecules and biopolymers as a faculty member at McMaster. Graham initially joined ACD/labs in 2007 as Product Manager leading the development of mass spectrometry software.
</blockquote>

The Analytical Scientist: How to Overcome the Challenges of Analytical Data Management

How to Overcome the Challenges of Analytical Data Management

The challenges related to analytical data that cross organizations and industries; and lessons learned through their own experience.

The meeting will dive into the topic of Dissolution Testing of semisolid formulations and spotlight on the most relevant instruments/accessories available. We will also discuss some tips and tricks for the method development of semisolids.
<blockquote>
Presenter: Karen Krauel-Göllner, PhD (Product Manager Dissolution, Agilent Technologies, Inc.)
</blockquote>
<blockquote>
Karen Krauel-Göllner is a registered pharmacist and holds a PhD in Pharmacy from the University of Otago, New Zealand. Karen has worked in various roles in the field of pharmaceutical development. For the last 5 years she has been working with Agilent Technologies and currently holds a position as product manager for dissolution systems.
</blockquote>
<blockquote>
Presenter: Ken Boda (Dissolution Product Specialist, Agilent Technologies, Inc.)
</blockquote>
<blockquote>
Ken joined Varian (now Agilent) in 2005 as an Applications Engineer and is now a Dissolution Product Specialist. Prior to working at Agilent, he worked in pharma specializing in dissolution testing and method development. As a Dissolution Product Specialist, Ken works with customers in determining the best systems for their needs and optimizing their work flows. He has also helped educate customers on dissolution science through webinars, the Dissolution Discussion Group, LinkedIn, and other channels.
</blockquote>
<blockquote>
Presenter: Bryan Crist (President, DissoAssist Consulting)
</blockquote>
<blockquote>
Bryan is currently the president of DissoAssist consulting based in Wilmington, NC since 2021. He provides consulting, coaching, and training services for dissolution and drug release in the pharmaceutical industry, specifically, the areas of product and method development and validation, technology transfer, regulatory and compendial compliance, automation, troubleshooting, aberrant data investigation, apparatus and instrument qualification, SOP development, and laboratory audits.
</blockquote>
<blockquote>
Previously, Bryan was a Scientific Affairs Manager with Agilent Technologies located in Cary, North Carolina, USA. His activities from 1997 until 2021 had focused on providing method and technical application support for dissolution and drug release testing in the pharmaceutical industry as well as working with VanKel, Varian and eventually Agilent R&amp;D, Marketing and Sales teams. Prior to 1997, Bryan performed analytical testing, supervised, and managed pharmaceutical laboratories with Bristol-Myers Squibb, Merck, AAI and Abbott Laboratories until he joined the dissolution equipment manufacturer VanKel.
</blockquote>
<blockquote>
Bryan has developed and routinely conducts numerous seminars related to dissolution and drug release testing. He’s provided numerous talks at exhibitions and conferences and has published numerous articles in journals and book chapters on dissolution related techniques and topics. He received his B.S. degree in Chemistry from Atlantic Christian College in Wilson, North Carolina. Bryan has been a former member of the USP Biopharmaceutics Expert Committee and is presently a member of several USP Expert Panels on Performance Verification Testing, Capsules, Performance Tests for Semisolid Dosage Forms and Solubility Criteria for Veterinary Drugs. He’s a Steering Committee member of the AAPS In-Vitro Release Dissolution Testing (IVRDT) Community Leadership Team, co-founder and co-moderator of the Dissolution Discussion Group (DDG) and is a current member of the American Chemical Society.
</blockquote>
<blockquote>
Presenter: Vivian Gray (Founder VA Gray Consulting; Managing Director of Dissolution Technologies)
</blockquote>
<blockquote>
Vivian has spent the last 40+ years involved in all aspects of dissolution testing and evaluating new dissolution technology. At the United States Pharmacopeia, she enjoyed a long career serving first as a bench chemist, supervisor and lastly as a liaison to various expert USP committees, including the Biopharmaceutics and Dissolution Expert Committee. In 1997, Vivian joined the DuPont-Merck Pharmaceuticals Company Analytical Research and Development Section as the Head of the Dissolution Group.
</blockquote>
<blockquote>
Vivian has been an invited speaker for conferences on 70 occasions (28 of these were international invitations), lecturing especially in the areas of dissolution method development and validation, FDA requirements in dissolution testing, troubleshooting dissolution method problems, and new dissolution technology and dosage forms. She is a proactive participant in the field as demonstrated by 54 publications, including 6 book chapters. Vivian has co-authored a book on dissolution testing called “Handbook of Dissolution Testing”, Third Edition, published in 2004.
</blockquote>

Agilent Technologies: Revisions to USP chapter 1724 - Dissolution Testing of Semisolids

Revisions to USP chapter 1724 - Dissolution Testing of Semisolids

Join us to get an update on the latest changes and additions to USP chapter <1724>.

Rev. to USP chapter 1724 - Dissolution Testing of Semisolids

The identification of extractables, leachables and chemical migration is a challenge for manufacturers and suppliers of packaging materials, medical devices and food contact materials. E&amp;L analytics is already complex, but it is compounded by legislative and regulatory efforts to recycle plastics. Analytical methods need to screen for not only the known components but also identify degradants and other unexpected compounds. Manufacturers, producers and retailers face the challenge of keeping up with evolving requirements and developing and adapting strategies to reduce plastic waste.
Thus, ways are being explored to incorporate more recycled plastics into products and packaging while maintaining excellent safety, quality and performance characteristics. As they innovate and combine new materials, companies must demonstrate safety and confirm compliance before bringing their products to market. This again increases the demand and importance of highly effective analytics.
Participation is free of charge. Presentations delivered in English.
Register now for this virtual event and share knowledge and challenges with peers and E&amp;L experts.
Who Should Attend?
The webinars are focused on the needs of scientists working in the area of Extractables &amp; Leachables and Food Contact Materials. During these webinars, attendees will learn:
<ul>
<li>Upcoming and new regulations in the field of food, pharma, biopharma and medical devices</li>
<li>Targeted and non-targeted screening workflows by using Waters_Connect</li>
<li>Characterization and structural elucidation of unknowns</li>
<li>Choice of chromatographic techniques, extraction methods and analytical standards &amp; reagents</li>
</ul>
<h3>EPISODE 1 - Virtual European Workshop on Extractables &amp; Leachables for Pharma &amp; Biopharma</h3>
<h5>Presentation: A risk-based assessment approach to extractable/leachable studies of plastic components and systems used in (bio)pharmaceutical manufacturing</h5>
<h5>Presentation: The Pattern Targeting Application</h5>
Register now &amp; join the discussion!
<blockquote>
Presenter: Lijun Song (Bioprocess Validations Specialist, 3M)
</blockquote>
<blockquote>
Lijun Song is a Senior Validation Engineer at the 3M filtration validation laboratory located in Belgium. After her PhD in Medicinal Chemistry at Ghent University, she joined the 3M validation team in 2019. She focuses on filter compatibility validation and extractable/leachable studies.
</blockquote>
<blockquote>
Presenter: Mike Ludlow (Science Lead working in the CMCAnalytical and Materials Science Team, Drug Development Solutions (part of Alliance Pharma Inc))
</blockquote>
<blockquote>
Mike Ludlow is the Science Lead working in the CMCAnalytical and Materials Science Team within Drug Development solutions based in Cambridgeshire, UK (Formerly known as LGC). The team supports an extensive external client base providing a variety of chromatographic and spectroscopic techniques covering both organic and inorganic characterisation. He has over 20 year’s experience in pharmaceutical analysis primarily in the areas of extractables and leachables testing and the identification of impurities such as Nitrosamines in a GxP environment. Before working for DDS, he worked in the Corporate Analytical Function of ICI’s Chemicals and Polymers Division providing support to R&amp;D scientists developing speciality polymer products.
</blockquote>
<blockquote>
Presenter: Jeff Goshawk (Applied Informatics, Research &amp; Development, Waters Corporation)
</blockquote>
<blockquote>
Jeff holds a BSc degree in Mathematics from the University of Portsmouth and a PhD in Applied Mathematics from the University of Liverpool. He joined Micromass as a software developer in July 2000 and worked on the development of MassLynx and the application managers ChromaLynx, MarkerLynx and MetaboLynx. In 2013 Jeff changed role joining the Waters Scientific Operations organisation as a member of the toxicology group and was exposed to the disciplines of sample preparation and sample acquisition in addition to developing data processing workflows using UNIFI. In 2017 Jeff transitioned into the Applied Informatics group in Scientific Operations to help to solve problems not addressed by mainstream software solutions. It was in this role that development on the Pattern Targeting Application began.
</blockquote>

Waters Corporation: Virtual European Workshops on Extractables & Leachables for Pharma & Biopharma

Virtual European Workshops on Extractables & Leachables for Pharma & Biopharma

Register now for this virtual event and share knowledge and challenges with peers and E&L experts.

Extractables & Leachables for Pharma & Biopharma

The next evolution in separation science is here as you go beyond the proper engineering of an LC system, the primary concern becomes the interaction of your analytes with elements in the instrument flow path. The Waters ACQUITY Premier UPLC System features MaxPeak High Performance Surfaces (HPS) Technology, which offers improvements in separation and detection of chemically complex analytes, enabling you to minimize the risk of undetected analytes – for increased efficiency and confidence in your results.
The ACQUITY Premier system minimizes the analyte loss, improving recovery, and limits of detection. Pairing with any Waters Mass Spectrometer, the ACQUITY Premier system enables you to confidently identify and quantify unknown compounds in complex samples and confirm trace components at the lowest possible levels.
Takeaways from this webinar will be:
<ul>
<li>HPS Technology: Using Surface Science Innovations to Reduce Bias in Chromatographic separations.</li>
<li>Automate workflows from development to manufacturing.</li>
<li>Observing the Impacts of MaxPeak Premier technology in Bioseperations in Peptide analysis, Glycans, and Oligos.</li>
</ul>
Who Should Attend?
<ul>
<li>Lab managers</li>
<li>General manager</li>
<li>Manager</li>
<li>Team lead</li>
<li>Scientist</li>
<li>Analyst</li>
<li>Chemist</li>
<li>Group Leaders</li>
<li>Research associate/ assistant</li>
</ul>
<blockquote>
Presenter: Mr. Manimaran U (Asst. Product Manager- Biopharma, Waters India Pvt Ltd - Bengaluru)
</blockquote>
<blockquote>
Moderator: Ms. Daya (Executive - Marketing Support, Demand Generation, Waters India Pvt Ltd - Bengaluru)
</blockquote>

Waters Corporation: Improving Chromatographic performance to next level with Waters Premier technology

Improving Chromatographic performance to next level with Waters Premier technology

The ACQUITY Premier system minimizes the analyte loss, improving recovery, and limits of detection.

Waters Premier technology

This webinar will demonstrate an LC-MS system that can perform both LC-MS analysis and LC-UV analysis. This single quad has a small footprint that allows it to adapt to different needs. With the following features, it is hoped that LC-MS will be more commonly used to analyze API, impurities, and perform quality control.
<ul>
<li>A novel deconvolution algorithm named &quot;Mass-it&quot; to identify the peaks</li>
<li>Dual Ion Source (DUIS) for simultaneous ESI/APCI ionization</li>
<li>Artificial intelligence for peak integration of mix samples</li>
<li>Contamination proof robustness</li>
<li>Reliability through automation, starting, cleaning, shutting down, etc.</li>
<li>Six minutes vacuum startup</li>
<li>Less than 3 milliseconds polarity switching</li>
</ul>
We will host a Q&amp;A session after the presentation to address any questions or comments.
<blockquote>
Presenter: Mridul Mandal, Ph.D. (Market Manager, Shimadzu Scientific Instruments)
</blockquote>
<blockquote>
Mridul Mandal, Ph.D. is currently working as a market manager -pharma/biopharma at Shimadzu Scientific Instruments. Before entering this position, he held numerous roles in academia and pharma CRO for over 12 years. He has published over 30 peer-reviewed publications and book chapters on mass spectrometry, chromatography, and other instrumentation in biomedical science
</blockquote>
<blockquote>
Presenter: Brian Domanski (Strategic Collaboration Scientist, Shimadzu Scientific Instruments)
</blockquote>
<blockquote>
Brian has over 10 years working to provide LC and SFC solutions for Pharma, as well as experience with a wide range of chromatography techniques including RP, NP, HILIC, IEX, SEC/GPC, and IC. His focus also includes scalable Informatics and Data Integrity solutions.
</blockquote>

Shimadzu: Revolutionary Single Quad LC-MS for Drug Development and Quality Control

Revolutionary Single Quad LC-MS for Drug Development and Quality Control

This webinar will demonstrate an LC-MS system that can perform both LC-MS analysis and LC-UV analysis.

Single Quad LC-MS for Drug Development and Quality Control

Unlock new perspectives with our accurate mass 101 webinar series.
Accelerate your workflows and expand your knowledge around accurate mass with these informative webinars.
In this webinar series, SCIEX applications scientists will explain the benefits of using accurate mass, sample analysis, instrument operation and data processing in real-time.
Get the inside scoop and register today!
<h3>Accurate mass 101: fundamentals</h3>
Accurate mass analysis coupled with liquid chromatography is a powerful qualitative and quantitative tool that offers a high degree of specificity, versatility and sensitivity. Make your experience using accurate mass more powerful by attending this webinar to gain a solid understanding of the fundamentals around this technology. We’ll start with an in-depth look at what it is, how it works, acquisition and workflow capabilities, and commonly used terminology.

Accurate mass 101: fundamentals

SCIEX applications scientists will explain the benefits of using accurate mass, sample analysis, instrument operation and data processing in real-time.