AdvanceBio HIC: a Hydrophobic HPLC Column for Monoclonal Antibody (mAb) Variant Analysis
Aplikace | 2019 | Agilent TechnologiesInstrumentace
Spotřební materiál, HPLC, LC kolony
ZaměřeníKlinická analýza
VýrobceAgilent Technologies
Klíčová slovaoxidation, mab, oxidized, bhp, methionine, met, hic, residues, mabs, mau, oxidant, shallower, advancebio, monoclonal, antibody, nist, recombinant, variants, chains, separation, time, hydrophobic, protein, stressed, exchanged, side, trp, amino, slower, interaction, reported, species, more, sulfoxide, accessible, reaction, reagents, column, stability, sample, retention, butylhydroperoxide, tert, hydroperoxide, interleukin, bsabs, degradations, kondaveeti, sandeep, hplc
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Quantitation of Oxidation Sites on a Monoclonal Antibody Using an Agilent 1260 Infinity HPLC-Chip/MS System Coupled to an Accurate-Mass 6520 Q-TOF LC/MS Application Note Authors Abstract Ravindra Gudihal Agilent Technologies India Pvt. Ltd. Bangalore, India The identification of oxidation sites…
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150 Absorbance (mAU) including intact mAbs, mAb fragments, engineered variants, and antibody-drug conjugates (ADCs) are being developed for the treatment of cancer and other diseases due to their excellent biocompatibility and high selectivity. The proliferation of monoclonal antibody therapeutics and…
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