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APPLICATION SOLUTIONS FOR OLIGONUCLEOTIDES - APPLICATION NOTEBOOK

Příručky | 2017 | WatersInstrumentace
Iontová mobilita, Software, HPLC, LC/TOF, LC/HRMS, LC/MS, LC/MS/MS, LC/SQ
Zaměření
Farmaceutická analýza, Proteomika
Výrobce
Waters
Klíčová slova
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High-throughput Screening of Oligonucleotides for Identity and Purity Assessment Using the ACQUITY QDa Detector and ProMass for MassLynx Robert E. Birdsall and Ying Qing Yu Waters Corporation, Milford, MA, USA A P P L I C AT I O N…
Klíčová slova
oligonucleotides, oligonucleotidespromass, promassqda, qdaacquity, acquitypurity, purityidentity, identitystrand, strandassessment, assessmentthroughput, throughputdata, datasynthetic, syntheticmass, massscreening, screeningmasslynx, masslynxacquired
[ APPLICATION NOTE ] Developing a Novel, Integrated LC-MS Workflow for High-resolution Monitoring and Characterization of Oligonucleotides Henry Shion, Robert Birdsall, and Ying Qing Yu Waters Corporation, Milford, MA, USA APPLICATION BENEFITS ■■ ■■ Optimized RP-UPLC mobile phase Methods that…
Klíčová slova
promass, promassoligonucleotide, oligonucleotideost, ostuplc, uplcoligonucleotides, oligonucleotidespolyt, polytacquity, acquitymasslynx, masslynxstrand, strandladder, ladderwaters, watersbio, bionote, notemass, massapplication
[ APPLICATION NOTE ] Evaluation of Alternative Ion-pairing Reagents in the Analysis of Oligonucleotides with the ACQUITY QDa Detector Robert E. Birdsall and Ying Qing Yu Waters Corporation, Milford, MA, USA APPLICATION BENEFITS ■■ ■■ Method compatibility with alternative Electrospray…
Klíčová slova
acquity, acquityoligonucleotides, oligonucleotidesqda, qdaoligonucleotide, oligonucleotidepairing, pairingalternative, alternativehfip, hfipreagents, reagentsdibutylamine, dibutylaminepolyt, polytbutylamine, butylaminedetector, detectorost, ostevaluation, evaluationdegree
ADDING COST EFFECTIVE MASS DETECTION FOR IMPROVED PRODUCTIVITY IN OLIGONUCLEOTIDE SCREENING ASSAYS Robert E. Birdsall, Sean M. McCarthy, Scott J. Berger, Maki Terasaki, Kenji Hiroseand Ying Qing Yu Biopharmaceutical Business Team, Waters Corporation, Milford, MA and Tokyo, Japan TUV Absorbance…
Klíčová slova
qda, qdapromass, promassacquity, acquityproductivity, productivitymass, massspectrum, spectrumscreening, screeningoligonucleotides, oligonucleotidesstraightforward, straightforwardassays, assaysdata, datathroughput, throughputcharge, chargestate, stateexpected
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