Size Exclusion Chromatography Analysis of a Monoclonal Antibody and Antibody Drug ConjugateAplikace | 2019 | Agilent TechnologiesInstrumentaceGPC/SECZaměřeníFarmaceutická analýzaVýrobceAgilent TechnologiesKlíčová slovaadc, monomer, vendor, sigmamab, mau, lmw, hmw, sec, mab, antibody, response, retention, mimic, species, min, advancebio, columns, backpressure, weight, molecular, monoclonal, time, hydrophobic, performance, exclusion, hwm, interactions, compared, sodium, qin, secondary, analysis, payloads, veronica, immunogenicity, superior, due, silu, column, lite, immunogenic, shape, separation, cqas, drug, existence, better, pharmacokinetics, adcs, conjugate
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High Resolution Size Exclusion Chromatography Analysis of Small Therapeutic Proteins
2020|Agilent Technologies|Aplikace
Application NoteBiopharmaHigh Resolution Size ExclusionChromatography Analysis of SmallTherapeutic ProteinsAuthorsSandeep Kondaveeti,Te‑Wei Chu, andAndrew CoffeyAgilent Technologies, Inc.AbstractProtein denaturation processes involving aggregation are among the factorsimpeding the development of stable protein drug formulations. The use of sizeexclusion chromatography (SEC) HPLC for determining purity...
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2019|Agilent Technologies|Brožury a specifikace
Fast Separations forAggregates and FragmentsAgilent AdvanceBio SEC 200 Å 1.9 μm columns Boost Your Productivity with FastAggregate and Fragment AnalysisSize exclusion chromatography (SEC) is a reference method for the qualitative andquantitative analysis of protein aggregates, such as monoclonal antibodies (mAbs)and antibody...
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2021|Agilent Technologies|Příručky
Agilent BiocolumnsAggregate/Fragment AnalysisApplication Compendium ContentsBackground2Getting Started3How to Guide - Size Exclusion Chromatography for BiomoleculeAnalysis - 5991-3651EN 4Featured Application NotesElevate Your mAb Aggregate Analysis - 5994-2709EN12222High-Resolution, High-Throughput Size Exclusion ChromatographyAnalysis of Monoclonal Antibodies - 5994-0828EN29Sensitive Native Mass Spectrometry of MacromoleculesUsing Standard Flow LC/MS...
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