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RNA Analysis for CRISPR by capillary electrophoresis with laser-induced fluorescence detection

 

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Gene Therapy and Oligonucleotide Compendium - Volume 1
Gene Therapy and Oligonucleotide Compendium Volume 1 Gene Therapy and Oligonucleotide Compendium Contents Introduction 4 Growing trends and emerging technologies for oligonucleotide and gene therapies 6 The global gene therapy & oligonucleotide market 8 Regional landscape North America EMEAI (Europe,…
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CRISPR Single Guide RNA Characterization by IP- RP-LC-MS with a Premier Oligonucleotide BEH 300 Å C18 Column
Application Note CRISPR Single Guide RNA Characterization by IP- RP-LC-MS with a Premier Oligonucleotide BEH 300 Å C18 Column Maissa M. Gaye, Chris Knowles, Balasubrahmanyam Addepalli, Matthew A. Lauber Waters Corporation Abstract The high speed, low cost, and reduced need…
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Size and Purity Assessment of Single-Guide RNAs by Anion-Exchange Chromatography (AEX)
Application Note Size and Purity Assessment of Single-Guide RNAs by Anion-Exchange Chromatography (AEX) Hua Yang, Stephan M. Koza, Ying Qing Yu Waters Corporation Abstract Single-guide RNA (sgRNA) is a critical element in the CRISPR/Cas9 Technology for gene editing, the size…
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Tunable Digestions of RNA Using RapiZyme™ RNases to Confirm Sequence and Map Modifications
Application Note Tunable Digestions of RNA Using RapiZyme™ RNases to Confirm Sequence and Map Modifications Balasubrahmanyam Addepalli, Tatiana Johnston, Christian Reidy, Matthew A. Lauber Waters Corporation Abstract RNA therapeutics such as sgRNA and mRNA are important modalities for Gene Therapy…
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