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Gene Therapy and Oligonucleotide Compendium - Volume 1

Příručky | 2020 | SCIEXInstrumentace
LC/TOF, LC/HRMS, LC/MS, LC/MS/MS, LC/QTRAP, Kapilární elektroforéza
Zaměření
Klinická analýza
Výrobce
SCIEX
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Advanced Therapeutic Medicinal Products: Adeno-associated Virus (AAV)
Advanced Therapeutic Medicinal Products: Adeno-associated Virus (AAV) The Promise of Viral Vector Gene Therapy using AAV 7000 Monogenic Diseases 20 of 22 4 Years Children with spinal muscular atrophy (SMA) given the ability to thrive with Zolgensma® (AAV) at 91%…
Klíčová slova
aav, aavglossary, glossarybioprocess, bioprocessmapping, mappingcapsid, capsiddiscovery, discoverygene, generegulatory, regulatorydevelopment, developmentspecifications, specificationstherapy, therapyvirus, virusadeno, adenoexpression, expressiontransduction
Genome Sizing Methodology for Genome Integrity Analysis of Adeno-Associated Viruses (AAV)
Genome Sizing Methodology for Genome Integrity Analysis of Adeno-Associated Viruses (AAV) Jane Luo, Tingting Li, Fang Wang, Sahana Mollah, Handy Yowanto SCIEX, Brea, California Introduction Adeno-associated virus (AAV) is a small (25-nm) virus that is composed of a non-enveloped icosahedral…
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aav, aavgenome, genomebenzonase, benzonaseintact, intactsize, sizepartial, partialagarose, agaroseproteinase, proteinasedenaturing, denaturingcapsids, capsidstreated, treatedsmall, smallblot, blotfiltrate, filtrateimpurities
Sensitive AAV Capsid Protein Impurity Analysis by CE Using Easy to Label Fluorescent Chromeo Dye P503
Sensitive AAV Capsid Protein Impurity Analysis by CE Using Easy to Label Fluorescent Chromeo Dye P503 Marcia Santos; SCIEX, Brea, California Introduction AAV or Adeno associated virus (Figure 1) is a popular class of gene therapy delivery vehicle used mostly…
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lif, lifsds, sdscapsid, capsidaav, aavdetection, detectiontherapy, therapydye, dyebuffer, bufferheat, heatfluorescent, fluorescentscheme, schemeelectrophoresis, electrophoresisattributed, attributedpyrilium, pyriliumproteic
Accurate Analysis of Double Stranded DNA over an Extended Size Range
Accurate Analysis of Double Stranded DNA over an Extended Size Range Capillary Electrophoresis-Laser Induced Fluorescence Detection (CE-LIF) Jane Luo, Mukesh Malik, Marcia Santos, Sahana Mollah and Handy Yowanto SCIEX, Brea, California Introduction Analysis of double stranded DNA (ds DNA) is…
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dna, dnasize, sizefragments, fragmentsgene, generestriction, restrictionvectors, vectorstherapy, therapylif, lifvaccines, vaccinesover, overextended, extendedgel, gellifluor, lifluorcell, cellmicrochip
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GCMS
ICPMS
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