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Gene Therapy and Oligonucleotide Compendium - Volume 1

Příručky | 2020 | SCIEXInstrumentace
LC/TOF, LC/HRMS, LC/MS, LC/MS/MS, LC/QTRAP, Kapilární elektroforéza
Zaměření
Klinická analýza
Výrobce
SCIEX
Klíčová slova
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Advanced Therapeutic Medicinal Products: Adeno-associated Virus (AAV) The Promise of Viral Vector Gene Therapy using AAV 7000 Monogenic Diseases 20 of 22 4 Years Children with spinal muscular atrophy (SMA) given the ability to thrive with Zolgensma® (AAV) at 91%…
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Genome Sizing Methodology for Genome Integrity Analysis of Adeno-Associated Viruses (AAV) Jane Luo, Tingting Li, Fang Wang, Sahana Mollah, Handy Yowanto SCIEX, Brea, California Introduction Adeno-associated virus (AAV) is a small (25-nm) virus that is composed of a non-enveloped icosahedral…
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Sensitive AAV Capsid Protein Impurity Analysis by CE Using Easy to Label Fluorescent Chromeo Dye P503 Marcia Santos; SCIEX, Brea, California Introduction AAV or Adeno associated virus (Figure 1) is a popular class of gene therapy delivery vehicle used mostly…
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Purity Analysis of Adeno-Associated Virus (AAV) Capsid Proteins using CE-LIF Technology Tingting Li, Handy Yowanto, Sahana Mollah SCIEX, Brea, CA Introduction Adeno-associated virus (AAV) is one of the most commonly used gene delivery vehicles in gene therapeutics. It is made…
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