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Multi-Attribute Analysis of Monoclonal Antibodies Using the Agilent InfinityLab 2D-LC Solution and Q-TOF MS

Aplikace | 2020 | Agilent TechnologiesInstrumentace
LC/TOF, LC/HRMS, LC/MS, LC/MS/MS, 2D-LC
Zaměření
Farmaceutická analýza
Výrobce
Agilent Technologies
Klíčová slova
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Application Note Biopharma/Pharma Determination of Multiple Attributes of Monoclonal Antibodies Simultaneous and parallel multi-attribute analysis using 3D-LC/MS with 2D multimethod option mAb SEC Size variants Protein A CEX LC/MS mAb Titer Charge variants Mol wt (MW) AA sequence PTM Cell…
Klíčová slova
trastuzumab, trastuzumaboriginator, originatorcex, cexmau, mauhmw, hmwhic, hiccho, choprotein, proteinvariants, variantscounts, countsdeconvoluted, deconvolutedclone, cloneclones, clonesmin, minvalve
Agilent AdvanceBio Desalting-RP Cartridges for Online Desalting in 2D‑LC/MS mAb Analysis Application Note Biotherapeutics and Biologics Authors Abstract Suresh Babu C.V. and Ravindra Gudihal This Application Note describes the use of a desalting cartridge in the second Agilent Technologies, Inc.…
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desalting, desaltingadvancebio, advancebiodimension, dimensionmab, mabsecond, seconddeconvoluted, deconvolutedagilent, agilentinnovator, innovatorheart, heartbiosimilar, biosimilarcutting, cuttingprotein, proteinmau, maucartridges, cartridgesvariants
Clone Selection Using the Agilent 1290 Infinity Online 2D-LC/MS Solution Application Note Biopharmaceuticals Authors Abstract Ravindra Gudihal and This Application Note describes the Agilent 1290 Infinity online 2D-LC/MS Syed Salman Lateef solution and proof of principle for clone selection and…
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counts, countsbiosimilar, biosimilarclone, clonedeconvoluted, deconvolutedamu, amumass, massinnovator, innovatoragilent, agilentcharge, chargepurification, purificationdesalting, desaltingrituximab, rituximabmin, minprotein, proteinmab
2D-LC/MS Characterization of Charge Variants Using Ion Exchange and Reversed-Phase Chromatography Multiple Heart-Cutting 2D-LC Analysis of Innovator versus Biosimilar Monoclonal Antibodies Application Note Biotherapeutics and Biologics Author Abstract Sonja Schneider The determination of charge variants is one of the most…
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dimension, dimensionbiosimilar, biosimilarsalt, saltinnovator, innovatorcharge, chargevariants, variantsfirst, firstrituximab, rituximabsecond, secondmain, mainwaste, wastebuffer, bufferphosphate, phosphatevariant, variantdeconvoluted
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