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Determination of Multiple Attributes of Monoclonal Antibodies

Aplikace | 2021 | Agilent TechnologiesInstrumentace
LC/TOF, LC/HRMS, LC/MS, LC/MS/MS, 2D-LC, GPC/SEC
Zaměření
Farmaceutická analýza
Výrobce
Agilent Technologies
Klíčová slova
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Application Note Pharma & Biopharma Multi-Attribute Analysis of Monoclonal Antibodies Using the Agilent InfinityLab 2D-LC Solution and Q-TOF MS Authors Gerd Vanhoenacker, Isabel Vandenheede, Pat Sandra, and Koen Sandra Research Institute for Chromatography (RIC) Kortrijk, Belgium Sonja Krieger, Sonja Schneider,…
Klíčová slova
mab, mabclone, cloneprotein, proteinsec, secheart, heartcutting, cuttingtocilizumab, tocilizumabmau, mauactemra, actemracounts, countsoriginator, originatorsupernatants, supernatantsdimension, dimensionmain, mainvariants
Consumables Workflow Ordering Guide Multi Dimensional HPLC Separation of Monoclonal Antibody Mixtures from Cell Culture Supernatants Therapeutic monoclonal antibodies (mAbs) come with structural complexity highly demanding towards analytics. Combining multiple analytical techniques on a system enables simultaneous multi-attribute analysis (MAA)…
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Cell Clone Selection Using the Agilent Bio-Monolith Protein A Column and LC/MS Application Note Biopharmaceuticals and Biosimilars Authors Abstract Emmie Dumont, Isabel Vandenheede, This application note describes how the Agilent Bio-Monolith Protein A column was Pat Sandra, Koen Sandra applied…
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clone, clonechain, chainmonolith, monolithtrastuzumab, trastuzumabheavy, heavyprotein, proteincounts, countsagilent, agilentbio, biolight, lightselection, selectionglycoform, glycoformmau, maucho, chotiter
Agilent AdvanceBio Desalting-RP Cartridges for Online Desalting in 2D‑LC/MS mAb Analysis Application Note Biotherapeutics and Biologics Authors Abstract Suresh Babu C.V. and Ravindra Gudihal This Application Note describes the use of a desalting cartridge in the second Agilent Technologies, Inc.…
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desalting, desaltingadvancebio, advancebiodimension, dimensionmab, mabsecond, seconddeconvoluted, deconvolutedagilent, agilentinnovator, innovatorbiosimilar, biosimilarheart, heartprotein, proteincutting, cuttingmau, maucartridges, cartridgesvariants
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