In-depth Peptide Mapping with Iterative MS/MS Acquisition on the Agilent 6545XT AdvanceBio LC/Q‑TOF
Aplikace | 2020 | Agilent TechnologiesInstrumentace
LC/TOF, LC/HRMS, LC/MS, LC/MS/MS
ZaměřeníFarmaceutická analýza
VýrobceAgilent Technologies
Klíčová slovantaylqmnslr, iterative, peptide, mapping, counts, auto, acquisition, assaymap, charge, precursors, eccs, mass, bravo, isoasp, agilent, depth, advancebio, peptides, workflow, rolling, native, protein, ptm, min, asp, excluded, biotherapeutic, trypsin, translational, characterization, overlaid, manufacture, integrated, forms, time, mab, yes, sheath, tkpreeqynstyr, sample, column, temperature, linfeng, fragment, identification, data, representative, gas, acquired, conventional
Podobná PDF
Enhancing The Quality Of Peptide Mapping Separation For The Analysis Of PTM
2017|Agilent Technologies|Aplikace
Enhancing The Quality Of Peptide Mapping Separation For The Analysis Of PTM Application Note Biotherapeutics and Biosimilars Author Introduction Suresh Babu C.V. Post-translational modifications (PTMs) on proteins such as monoclonal antibodies (mAbs) are critical quality attributes (CQAs) that define the…
Klíčová slova
peptide, peptidecounts, countsntaylqmnslr, ntaylqmnslradvancebio, advancebiodltmisr, dltmisrmab, mabeeeqynstr, eeeqynstrptms, ptmsdeamidated, deamidatedplus, plusdigest, digestmapping, mappingnonoxidized, nonoxidizedseparation, separationtryptic
LC/MS/MS Peptide Mapping Comparison of Innovator and Biosimilars of Rituximab
2019|Agilent Technologies|Aplikace
Application Note Biotherapeutics and Biosimilars LC/MS/MS Peptide Mapping Comparison of Innovator and Biosimilars of Rituximab Author Suresh Babu C.V. Agilent Technologies, Inc. Abstract The development and manufacturing of biosimilars require comparability studies with innovator biotherapeutic products. This Application Note presents…
Klíčová slova
innovator, innovatorpeptide, peptidecounts, countschain, chainmapping, mappingbiosimilar, biosimilarcharge, chargeunmodified, unmodifiedptms, ptmsheavy, heavyassaymap, assaymapttppvldsdgsfflyskl, ttppvldsdgsfflysklbiosimilars, biosimilarsmabs, mabsbravo
Making Peptide Mapping Routine with the Agilent 6545XT AdvanceBio LC/Q-TOF
2017|Agilent Technologies|Aplikace
Making Peptide Mapping Routine with the Agilent 6545XT AdvanceBio LC/Q-TOF Application Note Authors Introduction David L. Wong Monoclonal antibodies (mAbs) comprise a rapidly growing group of protein-based biomolecules being researched. Due to the heterogeneous nature of protein drugs, extensive analytical…
Klíčová slova
peptide, peptidemapping, mappingpeptides, peptidesadvancebio, advancebioassaymap, assaymapagilent, agilentbravo, bravonqvsltclvk, nqvsltclvkcharge, chargecounts, countsnative, nativemonoclonal, monoclonalantibody, antibodymass, massbioconfirm
An Integrated Workflow for Peptide Mapping of Monoclonal Antibodies
2017|Agilent Technologies|Aplikace
An Integrated Workflow for Peptide Mapping of Monoclonal Antibodies Application Note Biotherapeutics and Biosimilars Authors Introduction David L. Wong Monoclonal antibodies (mAbs) represent one of the fastest growing classes of drugs in the pharmaceutical industry. As a protein drug, the…
Klíčová slova
peptide, peptidemab, mabmapping, mappingcounts, countsassaymap, assaymapsgtasvvcllnnfypr, sgtasvvcllnnfypracquisition, acquisitionworkflow, workflowcharge, chargesequence, sequencewere, weredigestion, digestionnist, nistdiqmtqspstlsasvgdrvtitcsassr, diqmtqspstlsasvgdrvtitcsassrmtqspstlsasvgdrvtitcsassr
