Developing a Quantitative Surrogate Peptide Assay – Peptide mapping through MRM Optimization for Measuring Dulaglutide in a Rat PK Study
Aplikace | 2020 | WatersInstrumentace
LC/TOF, LC/HRMS, LC/MS, LC/MS/MS, LC/QQQ
ZaměřeníProteomika, Klinická analýza
VýrobceWaters
Klíčová slovadulaglutide, skyline, masslynx, peptide, mrm, rat, peptides, optimization, mapping, via, identification, surrogate, proteinworks, digested, quantitative, protein, interface, rapidly, step, preparation, workflow, assay, transitions, workflows, uplc, unifi, plus, acquity, express, exported, class, judiciously, catabolite, xevo, digestion, auto, optimize, develop, pursued, platform, includes, experiments, injected, refine, quanrecovery, here, precursor, interest, final, triple
Podobná PDF
How to Maximize Bioanalytical Performance of Fc-Fusion Proteins: Practical Sample Preparation and LC-MS/MS Workflows for Dulaglutide Quantification from Plasma
2020|Waters|Aplikace
[ APPLICATION NOTE ] How to Maximize Bioanalytical Performance of Fc-Fusion Proteins: Practical Sample Preparation and LC-MS/MS Workflows for Dulaglutide Quantification from Plasma Caitlin M. Dunning and Mark D. Wrona Waters Corporation, Milford, MA, USA APPLICATION BENEFITS ■ ■ ■…
Klíčová slova
hgegtftsdvssyleeqaak, hgegtftsdvssyleeqaakglpssiek, glpssiekdulaglutide, dulaglutideproteinworks, proteinworkspeptide, peptidelqc, lqcaccuracy, accuracyhgeg, hgegrsd, rsdhqc, hqclloq, lloqdigestion, digestionuplc, uplcstatistics, statisticsexpress
Quantification of Human Papillomavirus (HPV) Antigens in the Nonavalent Vaccine GARDASIL 9
2021|Waters|Aplikace
Application Note Quantification of Human Papillomavirus (HPV) Antigens in the Nonavalent Vaccine GARDASIL 9 Caitlin Dunning, Mark Wrona Waters Corporation Abstract Quantification and identity testing are an important part of vaccine substance and product batch release. Traditional methods can be…
Klíčová slova
peptide, peptideacquity, acquityadjuvant, adjuvantpremier, premierpeptides, peptidesuplc, uplcsurrogate, surrogatehpv, hpvmaxpeak, maxpeakdigestion, digestiondesorption, desorptionquantification, quantificationantigens, antigensvaccine, vaccinemasslynx
Versatile LC-MS/MS Solutions for the Evolving Bioanalysis Landscape
2024|Waters|Příručky
[ APPLICATION NOTEBOOK ] Versatile LC-MS/MS Solutions for the Evolving Bioanalysis Landscape Small Molecules Oligonucleotide Protein/Peptide Therapeutics Software Tools Targeted Imaging LC-MS/MS Solutions to Support Reliable, Sensitive and Efficient Workflows for the Bioanalysis of Drug Modalities Welcome to the Waters…
Klíčová slova
bioanalysis, bioanalysisimaging, imagingoligonucleotide, oligonucleotidetherapeutics, therapeuticsbioanalytical, bioanalyticalpeptide, peptidemolecules, moleculesprotein, proteintargeted, targetedhighlights, highlightstools, toolsquantitative, quantitativeread, readquantification, quantificationsmall
Automating Sample Preparation Workflows for Hybrid LC-MS/MS Bioanalysis of Protein Therapeutics: Quantification of Etanercept Using Affinity Purification and Digestion
2019|Waters|Aplikace
[ APPLICATION NOTE ] Automating Sample Preparation Workflows for Hybrid LC-MS/MS Bioanalysis of Protein Therapeutics: Quantification of Etanercept Using Affinity Purification and Digestion Paula Orens and Mary Lame Waters Corporation, Milford, MA, USA APPLICATION BENEFITS INTRODUCTION Automating a hybrid LC-MS/MS…
Klíčová slova
protein, proteinautomating, automatingbioanalysis, bioanalysishybrid, hybridtherapeutics, therapeuticsautomated, automatedworkflows, workflowsictcrpgwycalsk, ictcrpgwycalskimmunoaffinity, immunoaffinitypreparation, preparationpurification, purificationetanercept, etanerceptmanual, manualnormalized, normalizedraw
