Characterization of intact monoclonal antibody with microfluidic chip electrophoresis mass spectrometry
Postery | 2017 | Thermo Fisher ScientificInstrumentace
LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap, Kapilární elektroforéza
ZaměřeníKlinická analýza
VýrobceThermo Fisher Scientific
Klíčová slovarelative, biopharma, mab, intensity, abundance, mass, chip, exactive, finder, glycosylated, microfluidic, antibody, protein, primed, terminal, lysine, tic, clipping, sequence, delicate, pipetted, monoclonal, ave, intact, lys, variant, glycosylation, migration, variants, acknowled, eterogeneous, infring, lutamination, opharma, owerful, parated, bserved, charg, hannel, otein, ovides, werful, ultra, chien, dynam, hsun, pyroglutamination, mobility, nding, subsidia
Podobná PDF
Quick screening of intact antibody and antibody-drug conjugates with integrated microfluidic capillary electrophoresis and mass spectrometry
2017|Thermo Fisher Scientific|Aplikace
APPLICATION NOTE 72358 Quick screening of intact antibody and antibodydrug conjugates with integrated microfluidic capillary electrophoresis and mass spectrometry Authors Chien-Hsun Alex Chen,1 Stephane Houel,1 Terry Zhang,1 Brian J. Agnew,2 Shanhua Lin,3 Kai Zhou,1 Jonathan Josephs,1 Aran Paulus,1 and Andreas…
Klíčová slova
mab, mabnist, nistadc, adcmass, massrelative, relativezipchip, zipchipvariants, variantsbiopharma, biopharmaexactive, exactiveabundance, abundancelysine, lysinemodification, modificationdrug, drugconjugates, conjugatesintact
ZipChip™ System for Selected Thermo Scientific™ Mass Spectrometers - for CE/ESI-MS Analyses
|Thermo Fisher Scientific|Prezentace
ZipChip™ System for Selected Thermo Scientific™ Mass Spectrometers -- for CE/ESI-MS Analyses The world leader in serving science Content ZipChip System Introduction ZipChip Separation Mechanism Biopharmaceutical Application Examples Metabolomics Application and System Test Resources and Ordering Information 2 What is…
Klíčová slova
zipchip, zipchipexactive, exactivebiopharma, biopharmaabundance, abundancerelative, relativeseparation, separationassay, assaymab, mabbge, bgeachieved, achievedkit, kitsystem, systemchip, chipintact, intactnist
Thermo Scientific Q Exactive hybrid quadrupole-Orbitrap mass spectrometers with ZipChip system
2017|Thermo Fisher Scientific|Brožury a specifikace
A comprehensive CE/ESI-MS solution for BioPharma applications Thermo Scientific Q Exactive hybrid quadrupole-Orbitrap mass spectrometers with ZipChip system Fast CE Separation Nanospray Sensitivity HRAM Spectrometry A unique and powerful combination of CE/ESI and MS technology designed for BioPharmaceutical applications Thermo…
Klíčová slova
zipchip, zipchipbiopharma, biopharmaexactive, exactiverelative, relativeabundance, abundancefinder, findermab, mabmass, massemtasine, emtasineoption, optionlysine, lysinetrastuzumab, trastuzumabcarbohydrates, carbohydratesides, idesinfliximab
Evaluation of a microfluidic electrophoresis device coupled to an Orbitrap mass spectrometer for the characterization of biotherapeutics proteins
2017|Thermo Fisher Scientific|Postery
Evaluation of a microfluidic electrophoresis device coupled to an Orbitrap mass spectrometer for the characterization of biotherapeutics proteins. Stephane Houel1, Terry Zhang1, Erin Redman2, Scott Mellors2, Aaron Bailey1, Chris Petty2, Aran Paulus1, Kai Zhou1, Jonathan Josephs1., 1Thermo Fisher Scientific, San…
Klíčová slova
electrophoresis, electrophoresismab, mabnist, nistzipchip, zipchiplysine, lysineemtansine, emtansinemass, massintact, intactmicrofluidic, microfluidicabundance, abundancecharacterize, characterizecentimeter, centimeterrelative, relativeorbitrap, orbitrapspectrometer