Quick screening of intact antibody and antibody-drug conjugates with integrated microfluidic capillary electrophoresis and mass spectrometry
Aplikace | 2017 | Thermo Fisher ScientificInstrumentace
LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap, Kapilární elektroforéza
ZaměřeníKlinická analýza
VýrobceThermo Fisher Scientific
Klíčová slovamab, nist, adc, mass, relative, zipchip, variants, biopharma, exactive, abundance, lysine, modification, drug, conjugates, intact, electrophoresis, sliding, biotin, dibo, pyroglutamination, antibodies, heterogeneous, antibodydrug, antibody, adducts, orbitrap, hmr, glycosylation, terminal, site, eof, payload, quick, intensity, modifications, conjugation, screening, moiety, through, microfluidic, glycoforms, capillary, option, charge, distribution, heterogeneity, recombinant, characterization, orders, pmmp
Podobná PDF
Thermo Scientific Q Exactive hybrid quadrupole-Orbitrap mass spectrometers with ZipChip system
2017|Thermo Fisher Scientific|Brožury a specifikace
A comprehensive CE/ESI-MS solution for BioPharma applications Thermo Scientific Q Exactive hybrid quadrupole-Orbitrap mass spectrometers with ZipChip system Fast CE Separation Nanospray Sensitivity HRAM Spectrometry A unique and powerful combination of CE/ESI and MS technology designed for BioPharmaceutical applications Thermo…
Klíčová slova
zipchip, zipchipbiopharma, biopharmaexactive, exactiverelative, relativeabundance, abundancefinder, findermab, mabmass, massemtasine, emtasineoption, optionlysine, lysinetrastuzumab, trastuzumabcarbohydrates, carbohydratesides, idesinfliximab
ZipChip™ System for Selected Thermo Scientific™ Mass Spectrometers - for CE/ESI-MS Analyses
|Thermo Fisher Scientific|Prezentace
ZipChip™ System for Selected Thermo Scientific™ Mass Spectrometers -- for CE/ESI-MS Analyses The world leader in serving science Content ZipChip System Introduction ZipChip Separation Mechanism Biopharmaceutical Application Examples Metabolomics Application and System Test Resources and Ordering Information 2 What is…
Klíčová slova
zipchip, zipchipexactive, exactivebiopharma, biopharmaabundance, abundancerelative, relativeseparation, separationassay, assaymab, mabbge, bgeachieved, achievedkit, kitsystem, systemintact, intactchip, chipvariants
Characterization of intact monoclonal antibody with microfluidic chip electrophoresis mass spectrometry
2017|Thermo Fisher Scientific|Postery
POSTER NOTE 65000 Characterization of In Characterization of Chien-Hsun intact monoclonal antibody Chen1, Andreas Krupke2,with Stephane H 1Thermo Fisher Scientific, Chromatography and microfluidic chip electrophoresis mass spectrometry Authors Chien-Hsun Chen,1 Andreas Krupke,2 Stephane Houel,1 Aaron Bailey,1 Aran Paulus,1 Daniel Lopez-Ferrer,1…
Klíčová slova
relative, relativebiopharma, biopharmamab, mabintensity, intensityabundance, abundancemass, masschip, chipexactive, exactivefinder, finderglycosylated, glycosylatedmicrofluidic, microfluidicantibody, antibodyprotein, proteinterminal, terminalprimed
Evaluation of a microfluidic electrophoresis device coupled to an Orbitrap mass spectrometer for the characterization of biotherapeutic proteins
2017|Thermo Fisher Scientific|Postery
Evaluation of a microfluidic electrophoresis device coupled to an Orbitrap mass spectrometer for the characterization of biotherapeutic proteins. Stephane Houel1, Terry Zhang1, Erin Redman2, Scott Mellors2, Aaron Bailey1, Chris Petty2, Aran Paulus1, Kai Zhou1, Jonathan Josephs1., 1Thermo Fisher Scientific, San…
Klíčová slova
zipchip, zipchipelectrophoresis, electrophoresisnist, nistmab, mabintact, intactmicrofluidic, microfluidicmass, masslysine, lysinetrastuzumab, trastuzumaborbitrap, orbitrapdevice, devicepeptide, peptideemtansine, emtansineexactive, exactivesub
