LCMS
Další informace
WebinářeO násKontaktujte násPodmínky užití
LabRulez s.r.o. Všechna práva vyhrazena. Obsah dostupný pod licencí CC BY-SA 4.0 Uveďte původ-Zachovejte licenci.
 

Podobná PDF

Toggle
this study we have analyzed two commercially available drug products: rituximab (trade names MabThera and Rituxan®) and denosumab (trade names Prolia® and XGEVA®). FIGURE 1. General structure of mAbs and their biological and physico-chemical characteristics. Physicochemical Characteristics Biological Characteristics High…
Klíčová slova
chain, chainheavy, heavyrituximab, rituximabmodifications, modificationspeptide, peptidemodification, modificationgradient, gradientmapping, mappingdifferent, differentexactive, exactiveheterogeneity, heterogeneitysequence, sequencelight, lightnames, namesterminal
APPLICATION NOTE 21688 Robust and reproducible peptide mapping and intact mass analysis workflows on a single instrument platform Authors Amy Farrell , Kai Scheffler , Ken Cook 2, Martin Samonig2, David Munoz2, Alexander Schwahn2, and Jonathan Bones1 1 Characterisation and…
Klíčová slova
somatotropin, somatotropinpeptide, peptidedigestion, digestionpeptides, peptidesdisulfide, disulfidecleavage, cleavageprotein, proteinmissed, missednative, nativesequence, sequencemapping, mappingmodifications, modificationsdigest, digestdeamidation, deamidationabundance
APPLICATION NOTE 73672 Accelerating monoclonal antibody peptide mapping with high acquisition speed Orbitrap-based MS Authors: Phil Widdowson, Amy Claydon, Tom Buchanan Thermo Fisher Scientific, Hemel Hempstead, UK Keywords: Peptide mapping, monoclonal antibody, mAb, post-translational modification, PTM, high throughput analysis, golimumab,…
Klíčová slova
golimumab, golimumabterminal, terminaldeamidation, deamidationglycosylation, glycosylationpeptide, peptidelysine, lysinemodification, modificationmapping, mappingdigest, digestrelative, relativepeptides, peptidesoxidation, oxidationmodifications, modificationssmart, smartglycopeptide
APPLICATION NOTE 21782 Comparison of alternative approaches to trypsin protein digestion for reproducible and efficient peptide mapping analysis of monoclonal antibodies Authors Silvia Millán-Martín, Craig Jakes, Noemi Dorival-García, Nicola McGillicuddy, Sara Carillo, Amy Farrell, Jonathan Bones National Institute for Bioprocessing…
Klíčová slova
smart, smartdigest, digestadalimumab, adalimumabdigestion, digestionmagnetic, magneticmodifications, modificationsalternative, alternativepeptide, peptiderapid, rapidmapping, mappingdeamidation, deamidationrelative, relativenistmab, nistmabinduced, inducedoxidation
Další projekty
Sledujte nás
Další informace
WebinářeO násKontaktujte násPodmínky užití
LabRulez s.r.o. Všechna práva vyhrazena. Obsah dostupný pod licencí CC BY-SA 4.0 Uveďte původ-Zachovejte licenci.