Confident peptide mapping and disulfide bond analysis of an IgG2 monoclonal antibody
Aplikace | 2020 | Thermo Fisher ScientificInstrumentace
LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap
ZaměřeníProteomika, Klinická analýza
VýrobceThermo Fisher Scientific
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Biopharma Protein solutions eBook Protein therapeutics: At a glance Protein therapeutics are a type of biotherapeutics derived from genetically engineered human proteins. They offer several advantages over small-molecule drugs, allowing for more precise targeting of complex functions. Compared to chemical…
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Robust and reproducible peptide mapping and intact mass analysis workflows on a single instrument platform
2017|Thermo Fisher Scientific|Aplikace
APPLICATION NOTE 21688 Robust and reproducible peptide mapping and intact mass analysis workflows on a single instrument platform Authors Amy Farrell , Kai Scheffler , Ken Cook 2, Martin Samonig2, David Munoz2, Alexander Schwahn2, and Jonathan Bones1 1 Characterisation and…
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2015|Thermo Fisher Scientific|Postery
this study we have analyzed two commercially available drug products: rituximab (trade names MabThera and Rituxan®) and denosumab (trade names Prolia® and XGEVA®). FIGURE 1. General structure of mAbs and their biological and physico-chemical characteristics. Physicochemical Characteristics Biological Characteristics High…
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2018|Thermo Fisher Scientific|Aplikace
APPLICATION NOTE 21782 Comparison of alternative approaches to trypsin protein digestion for reproducible and efficient peptide mapping analysis of monoclonal antibodies Authors Silvia Millán-Martín, Craig Jakes, Noemi Dorival-García, Nicola McGillicuddy, Sara Carillo, Amy Farrell, Jonathan Bones National Institute for Bioprocessing…
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