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Quantitative Analysis and Determination of Molecular Weight of siRNA Type Oligonucleotides by LCMS™-8060

 

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C10G-E097 Oligonucleotide Therapeutics Solution Guide Types and Characteristics of Oligonucleotide Therapeutics Oligonucleotide therapeutics are nucleic acid polymers generally comprised of a few to several dozen bases However, it is a practical problem that oligonucleotide therapeutics are degraded and excreted rapidly…
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Application News No. C215 LC-MS Determination of Molecular Mass and Quantification of Oligonucleotide Therapeutics Using Quadrupole Time-of-Flight Mass Spectrometer LCMS™-9030  Overview Oligonucleotide therapeutics are synthetic oligonucleotides that demonstrate their medical efficacy through binding to target genes or target proteins…
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Application News No. C231 Liquid Chromatography Mass Spectrometry Verification of Quantitativity and Confirmation of Molecular Weight of Oligonucleotide therapeutics Using LCMS™-8060 „ Overview „ Sample Oligonucleotide therapeutics are synthetic oligonucleotides which demonstrate medical efficacy by bonding with target genes or…
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[ APPLICATION NOTEBOOK ] APPLICATION SOLUTIONS FOR OLIGONUCLEOTIDES Table of Contents Introduction – UPLC Analysis of Synthetic Oligonucleotides......................................................................................................................... 4 [ HPLC & UPLC Separations ] Real-Time Analysis of RNAi Duplexes ....................................................................................................................................................................... 8 Semi-Preparative Scale Single-Stranded RNA Purification .......................................................................................................................... 11 Oligonucleotide…
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