Mass Spectrometric Characterization of Antibody-siRNA Conjugates using the Agilent 6545XT AdvanceBio LC/Q‑TOF
Aplikace | 2020 | Agilent TechnologiesInstrumentace
LC/TOF, LC/HRMS, LC/MS, LC/MS/MS
ZaměřeníFarmaceutická analýza
VýrobceAgilent Technologies
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Mass Spectrometric Characterization of Antibody-RNA Conjugates using the Agilent 6545XT AdvanceBio LC/Q-TOF
2020|Agilent Technologies|Postery
Poster Reprint ASMS 2020 WP 004 Mass Spectrometric Characterization of Antibody-RNA Conjugates using the Agilent 6545XT AdvanceBio LC/Q-TOF David L. Wong Agilent Technologies, Inc., Santa Clara, CA, USA Introduction Experimental Antibody-RNA Conjugates have drug-like The antibody was partially reduced with…
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Characterization of Antibody‑Drug Conjugates Using 2D-LC and Native MS
2021|Agilent Technologies|Aplikace
Application Note Biopharma/Pharma Characterization of Antibody‑Drug Conjugates Using 2D-LC and Native MS Authors David L. Wong and Sarah M. Stow Agilent Technologies, Inc. Abstract Antibody drug conjugates (ADCs), which comprise a monoclonal antibody (mAb) conjugated to a small molecule drug…
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Intact & Subunit Analysis Using Reversed Phase - Agilent BioHPLC Columns Application Compendium
2020|Agilent Technologies|Příručky
Agilent-NISTmAb Intact & Subunit Analysis Using Reversed Phase Agilent BioHPLC Columns Application Compendium Contents Agilent-NISTmAb Standard (P/N 5191-5744; 5191-5745) was aliquoted from NISTmAb RM 8671 batch. Quality control (QC) testing is performed using Agilent LC-MS system. QC batch release test…
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Sensitive Native Mass Spectrometry of Macromolecules Using Standard Flow LC/MS
2020|Agilent Technologies|Aplikace
Application Note Pharma & Biopharma Sensitive Native Mass Spectrometry of Macromolecules Using Standard Flow LC/MS Author David L. Wong Agilent Technologies, Inc. Abstract Native mass spectrometry can be used for a variety of protein-based applications, such as protein-protein interaction, protein-ligand…
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native, nativeprotein, proteincounts, countsintact, intactdeconvoluted, deconvolutedamu, amumyoglobin, myoglobinmass, massapomyoglobin, apomyoglobincharge, chargeholomyoglobin, holomyoglobinheme, hemecomplexes, complexestetramer, tetramerdenatured