Přehled HPLC a LC/MS aplikací od Agilent Technologies H1/2022

Jaké aplikační nebo technické možnosti přinášejí nejnovější modely kapalinových chromatografů nebo jejich spojení s hmotnostními spektrometry a dalšími periferiemi např. pro automatizaci přípravy vzorků nebo vysokou propustnost?

Zapomínat nesmíme ani na nejnovější chromatografické HPLC kolony nebo spotřební materiál, který dokáže nejednou Váš aplikační požadavek vyřešit lépe, nebo Vám ulehčit každodenní rutinu více, než ten nejvýkonnější hardware.

Podívejte se na trendy a novinky v dostupné literatuře z prvního pololetí 2022 od Agilent Technologies.

LabRulez: Přehled HPLC a LC/MS aplikací od Agilent Technologies H1/2022

Kapalinová chromatografie (HPLC) 👉 Knihovna (23)

• Converting a ChP Method of Related Compounds Analysis in Human Insulin to Agilent InfinityLab Poroshell 120 Columns (Aplikace | 2022)

• High-Throughput N-Glycans Profiling of Monoclonal Antibodies EG2-hFc and Rituximab Using the Agilent AdvanceBio Gly-X N-Glycan Prep with InstantPC Kit (Aplikace | 2022)

• A Workflow for Rapid Sample Preparation and Exoglycosidase Characterization of N-Glycans in Antibodies (Aplikace | 2022)

• Oligonucleotide Purification using Ion Pair Reversed-Phase Liquid Chromatography (Ostatní | 2022)

• Oligonucleotide Purification using Anion Exchange Liquid Chromatography (Ostatní | 2022)

• Best Practices for Using an Agilent LC System - Technical Note (Technické články | 2022)

• Your InfinityLab HPLC Productivity Roadmap (Ostatní | 2022)

• Agilent InfinityLab Quick Change Valve G5640A - Instructions (Manuály | 2022)

• Improved Metabolomic Analysis Using an Iron-Free Flow Path (Aplikace | 2022)

• Analysis of Full/Empty Capsid Ratios in Adeno-Associated Virus 1 and 6 Serotypes Using Biocompatible Liquid Chromatography (Aplikace | 2022)

• Analysis of Lipid Nanoparticle Composition (Aplikace | 2022)

• Temperature-Dependent Reaction Monitoring of an Ester Hydrolysis (Aplikace | 2022)

• ASMS: Analysis of Adeno-Associated Virus Quality Attributes with LC-FLD-(MS) (Postery | 2022)

• High-Throughput Human Serum and Immunoglobulin G N-Glycome Profiling with the Agilent AdvanceBio Gly-X InstantPC Technology for Biomarker Discovery (Aplikace | 2022)

• Analysis of Sialylated Glycan Modification in Protein Therapeutics (Aplikace | 2022)

• Agilent Infinity Purification Solution Site Preparation Checklist (Manuály | 2022)

• ASMS: It’s time for LC/MS to Replace HPLC for Routine Cannabinoid Testing (Postery | 2022)

• Online Amino Acid Analysis for Spend Media Control (Aplikace | 2022)

• Online LC Monitoring of a Hydrolysis of Organic Acid Esters by Means of a Flow Chemistry Reactor (Aplikace | 2022)

• Fast and Selective Purification of Oligonucleotides Using Preparative HPLC/MS and Software Support (Aplikace | 2022)

• Demonstrating Inertness for the Analysis of Nucleotides on the Agilent 1290 Infinity II Bio LC (Technické články | 2022)

• Demonstrating Inertness for the Analysis of Nucleotides on the Agilent 1290 Infinity II Bio LC (Technické články | 2022)

• Handbook of ICP-QQQ Applications using the Agilent 8800 and 8900 (Příručky | 2022)

HPST: Kapalinové chromatografy Agilent Technologies 1260 BIO HPLC, 1290 UHPLC , SFC, 1220 HPLC

2D Kapalinová chromatografie (HPLC) 👉 Knihovna (3)

• Simultaneous Impurity Analysis and Enantioseparation of Atenolol Using Achiral-Chiral 2D-LC (Aplikace | 2022)

• Characterization of the Anticoagulant Nadroparin by 2D-LC With High‑Resolution MS (Aplikace | 2022)

• Analysis of Peptide/Protein-Related Impurities Using the Integrated Solution of Bio 2D-LC/Q-TOF in Agilent MassHunter Software (Technické články | 2022)

Hmotnostní spektrometrie s jednoduchým kvadrupólem (LC/MS) 👉 Knihovna (5)

• Simultaneous Impurity Analysis and Enantioseparation of Atenolol Using Achiral-Chiral 2D-LC (Aplikace | 2022)

• ASMS: Ensuring Reliable Results using Agilent’s New 7 Analyte System Suitability Standard with WalkUp and the LC/MSD iQ (Postery | 2022)

• ASMS: It’s time for LC/MS to Replace HPLC for Routine Cannabinoid Testing (Postery | 2022)

• ASMS: Comparing LC/MS with LC/MS/MS for the Simultaneous Extraction and Analysis of Water-Soluble Vitamins and Fat-Soluble Vitamins in Multivitamin Supplements (Postery | 2022)

• Fast and Selective Purification of Oligonucleotides Using Preparative HPLC/MS and Software Support (Aplikace | 2022)

HPST: Hmotnostní spektrometry pro kapalinovou chromatografii Agilent Technologies iQ SQ, 6475 QQQ, 6545 Q-TOF

Tandemová hmotnostní spektrometrie s trojitým kvadrupólem (LC/QQQ) 👉 Knihovna (43)

• Rapid and Sensitive Quantitation of Metanephrines and 3-Methoxytyramine in Human Plasma Using an Agilent Ultivo Triple Quadrupole LC/MS (Aplikace | 2022)

• Analysis of Pesticides in Celery (Aplikace | 2022)

• Determination of Multiclass, Multiresidue Pesticides in Bell Peppers (Aplikace | 2022)

• Determination of Multiclass, Multiresidue Pesticides in Spring Leaf Mix (Aplikace | 2022)

• Determination of Per and Polyfluoroalkyl Substances in Soils Using Carbon S SPE by LC/MS/MS (Aplikace | 2022)

• Quantitative LC/MS/MS Analysis of Ethyl Glucuronide and Ethyl Sulfate Using a Charged Surface-C18 Column (Aplikace | 2022)

• Analysis of 510 Pesticides in Black Pepper (Aplikace | 2022)

• Quantitative Analysis of Pesticides in Celery and Grape (Aplikace | 2022)

• Ultra Fast Analysis of the Cocaine Metabolite (BZE) in Urine (Aplikace | 2022)

• Ultrafast Plasma Protein Binding Analysis (Aplikace | 2022)

• A study of SIRT1- and SIRT2‑Mediated Deacetylation (Aplikace | 2022)

• Analysis of Pharmaceuticals and Personal Care Products (PPCPs) as Contaminants in Drinking Water by LC/MS/MS Using Agilent Bond Elut PPL (Aplikace | 2022)

• Analysis of Adrenal Steroids in Dried Blood Spots and Serum Using Agilent Ultivo LC/TQ (Aplikace | 2022)

• Absolute Quantitation of Fragile Metabolites by Isotope Dilution Mass Spectrometry on the Agilent 6495 Triple Quadrupole LC/MS (Aplikace | 2022)

• LC/Q-TOF Marker Identification to TQ LC/MS Targeted Quantitation (Aplikace | 2022)

• Analysis of Cannabinoids and their Metabolites in Human Urine Using the Agilent Chem Elut S Plate by LC/MS/MS (Aplikace | 2022)

• Quantification of Nine Nitrosamine Impurities in Sartan Drugs Using an Agilent GC-TQ (Aplikace | 2022)

• Analysis of Perfluoroalkyl Substances in Textile and Leather Using the Agilent 6470 Triple Quadrupole LC/MS (Aplikace | 2022)

• ASMS: High fidelity legacy-to-modern method transfer on the 6475 triple quadrupole LC/MS platform for large output production labs (Postery | 2022)

• ASMS: Sample Preparation Comparison of Large Peptide Quantification in Biological Matrix (Postery | 2022)

• ASMS: Comprehensive workflow for targeted cell metabolomics using automated sample preparation, HILIC chromatography, LC/TQ, and a statistical analysis software suite (Postery | 2022)

• ASMS: Active & iterative data-dependent reinjection logic for maintaining throughput, uptime, and consistency in triple quadrupole LC/MS analysis (Postery | 2022)

• ASMS: Screening, Identification, and Quantitation of Drugs of Abuse in Human Whole Blood by LC/Q-TOF and LC/MS/MS (Postery | 2022)

• ASMS: An end-to-end software algorithm for LC/MS/MS method development, optimization, and QA/QC deployment (Postery | 2022)

• ASMS: An efficient pseudo-targeted metabolomics workflow based on liquid chromatography coupled with mass spectrometry (Postery | 2022)

• Simultaneous Identification, Confirmation and Quantitation of Impurity in Antibiotics Formulations Using Mixed Scan Mode of Ultivo LC/TQ (Postery | 2022)

• Highly Sensitive LC/MS/MS Method for the Simultaneous Quantification of Mutagenic Azido Impurity Analogues in Five Different Sartan APIs and Formulations (Aplikace | 2022)

• ASMS: Analysis of Multiclass Pesticide Residues in Dried Parsley Sample Using LC-MS and GC-MS (Postery | 2022)

• ASMS: Quantitative LC/MS/MS Analysis of Ethyl Glucuronide and Ethyl Sulfate using Charged Surface-C18 Column (Postery | 2022)

• ASMS: Development and Validation of a Quantitative Method for Multiresidue Pesticides in Food Matrices Using the Agilent 6475 LC/TQ System (Postery | 2022)

• ASMS: Multi-residue Method Development Using Agilent 6475 LC/TQ System Implemented with Intelligent Optimization Software: Application to Forensic Drug Screening (Postery | 2022)

• ASMS: Accelerated lifetime testing with real-time Early Maintenance Feedback (EMF) diagnostic monitoring on the 6475 triple quadrupole LC/MS (Postery | 2022)

• ASMS: Impact of Quadrupole Mass Resolution on Analytical Performance of MS/MS Assays using a triple quadrupole LC/MS system (Postery | 2022)

• ASMS: An Easier, More Robust, and Faster Low- flow Quantitative Proteomics Approach (Postery | 2022)

• ASMS: Message in a Bottle: Analysis of Phosphatidylethanols in Whole Blood by Novel Solid Phase Extraction and LC/TQ (Postery | 2022)

• ASMS: I Knew You Were Trouble: Trials and Tribulations of Method Development for Extended Pathway, Low-Volume, Plasma Catecholamine Assay by LC-MS/MS (Postery | 2022)

• ASMS: Rapid LC-MS/MS workflow for sensitive quantitation of Metanephrines and 3- Methoxytyramine in human plasma (Postery | 2022)

• ASMS: Comparing LC/MS with LC/MS/MS for the Simultaneous Extraction and Analysis of Water-Soluble Vitamins and Fat-Soluble Vitamins in Multivitamin Supplements (Postery | 2022)

• Determination of Per and Polyfluoroalkyl Substances in Drinking Water Using Agilent Bond Elut PFAS WAX SPE and LC/MS/MS (Aplikace | 2022)

• Analysis of Pesticide Residues in Spinach Using AOAC Pigmented dSPE with Carbon S Cleanup and LC/MS/MS (Aplikace | 2022)

• Analysis of Per- and Polyfluoroalkyl Substances (PFAS) in Aqueous Samples Per EPA Draft Method 1633 (Aplikace | 2022)

• Agilent 6475 triple quadrupole LC/MS (Brožury a specifikace | 2022)

• Agilent 6470B Triple Quadrupole LC/MS with Agilent Jet Stream Source (Brožury a specifikace | 2022)

Tandemová hmotnostní spektrometrie s vysokým rozlišením a přesnou hmotou (LC/Q-TOF) 👉 Knihovna (27)

• Ultrafast Plasma Protein Binding Analysis (Aplikace | 2022)

• LC/Q-TOF Marker Identification to TQ LC/MS Targeted Quantitation (Aplikace | 2022)

• HRdm 2.0: Maximize Your IM Resolution Without Sacrificing Drift Range, Mass Range, or Data Acquisition Time (Technické články | 2022)

• Optimizing Separation of Oligonucleotides with Anion‑Exchange Chromatography (Aplikace | 2022)

• ASMS: An Innovation Solution of Multi-Methods Analysis for Central Carbon Metabolism and Broad Coverage of Metabolites Classes (Postery | 2022)

• ASMS: Metabolomics Study of Rodenticide Poisoning using Serum Samples with LCMS-QTOF Instrumentation (Postery | 2022)

• ASMS: Comparative Study of High-Resolution Q- TOF Fast Polarity Switching versus Single Polarity Data Acquisition on Mass Accuracy, Resolution and Analytical Sensitivity (Postery | 2022)

• ASMS: Comparison of High-Resolution Data Dependent MSMS Strategies for Best Precursor Coverage of Aqueous Film Forming Foam Formulations (Postery | 2022)

• ASMS: Analysis of Adeno-Associated Virus Quality Attributes with LC-FLD-(MS) (Postery | 2022)

• ASMS: Screening, Identification, and Quantitation of Drugs of Abuse in Human Whole Blood by LC/Q-TOF and LC/MS/MS (Postery | 2022)

• ASMS: An efficient pseudo-targeted metabolomics workflow based on liquid chromatography coupled with mass spectrometry (Postery | 2022)

• ASMS: Refined LC/Q-TOF Methodology for Identification and Profiling of Bile Acids Produced from the Gut Microbiome (Postery | 2022)

• ASMS: Multi-Attribute Monitoring of Antibody Variants through Hydrophobic and Cation- Exchange Chromatography Coupled with Native Mass Spectrometry (Postery | 2022)

• ASMS: Bottom-up and Top-down Disulfide Bond Mapping of Beta-lactoglobulin on a Q-TOF with the Capability to Perform both CID and ECD (Postery | 2022)

• ASMS: Comprehensive, Automated, and Integrated Software for Oligonucleotide Characterization and Sequence Confirmation (Postery | 2022)

• ASMS: The impact of Matrix effect in extraction efficiency of N-nitroso-N-methyl-4- aminobutyric acid in Metformin Extended- Release tablets using ESI-LC/HRMS (Postery | 2022)

• ASMS: Fine Structural Elucidation of Phospholipids with Practical Electron- Based Fragmentation on Q-TOF Instruments (Postery | 2022)

• ASMS: Analytical and Informatic Benefits from Automated Conversion of Ion Mobility Arrival Times to Collision Cross Sections in Raw Data Files (Postery | 2022)

• ASMS: Automated sample introduction method for high-throughput intact native protein analysis using collision induced unfolding coupled with drift-tube ion mobility-mass spectrometry (Postery | 2022)

• ASMS: A Comprehensive Untargeted Metabolomics LC/Q-TOF Workflow with an Unknowns Identification Strategy to Identify Plasma Metabolite Shifts in a Mouse Model (Postery | 2022)

• ASMS: Novel Algorithms and Visualizations for Discovering Polymers and Chemical Series in Industrial and Environmental Applications (Postery | 2022)

• ASMS: Comparison of Drift-tube Ion Mobility and Structures for Lossless Ion Manipulation(SLIM) for the Characterization of Polysorbate, Polyethers, Surfactants Compounds (Postery | 2022)

• Adeno-Associated Virus Identity Confirmation in Biopharma by LC/MS (Ostatní | 2022)

• Characterization of the Anticoagulant Nadroparin by 2D-LC With High‑Resolution MS (Aplikace | 2022)

• An Integrated Workflow for the Analysis of Oligonucleotides and Their Impurities by Agilent High-Resolution LC/(Q-)TOF Mass Spectrometry (Aplikace | 2022)

• Analysis of Peptide/Protein-Related Impurities Using the Integrated Solution of Bio 2D-LC/Q-TOF in Agilent MassHunter Software (Technické články | 2022)

• High-throughput, Ion-Pairing-Free, HILIC Analysis of Oligonucleotides Using Agilent RapidFire Coupled to Quadrupole Time-of-Flight Mass Spectrometry (Aplikace | 2022)