<h3><a target="_blank" rel="noopener noreferrer" href="https://www.isc2026.org/">O ISC 2026</a></h3><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/companies/314">Mezinárodní sympozium o chromatografii (International Symposium on Chromatography, ISC)</a> představuje nejstarší konferenční sérii v oblasti separačních věd. Sympozia ISC jsou pořádána od roku 1956 v každém sudém roce. ISC patří mezi nejvýznamnější světová setkání zaměřená na diskusi všech forem chromatografie a separačních metod, s širokým pokrytím technik a aplikací.Hlavním zaměřením sympozia bude přínos chromatografie a separačních věd pro potřeby farmaceutického, environmentálního, potravinářského a zdravotnického průmyslu, stejně jako pro vědu a medicínu. Program sympozia bude tyto oblasti reflektovat a upozorní na nové výzvy i vznikající příležitosti ve vývoji, aplikaci a marketingu separačních a detekčních systémů a metod.Nedílnou součástí vědeckého programu přednášek a posterových sekcí bude mezinárodní výstava a firemní semináře zaměřené na instrumentaci a služby v oblasti chromatografie, separačních věd a hmotnostní spektrometrie. ISC 2026 nabídne ideální platformu pro vědeckou výměnu a networking účastníků z akademické sféry, průmyslu i státních výzkumných institucí.<h3>Klíčová data sympozia ISC 2026</h3>6.–10. září 2026<ul><li>15. ledna 2026 – Zahájení registrace za zvýhodněnou cenu (early-bird) a podávání abstraktů</li><li>11. března 2026 – Uzávěrka podávání abstraktů (ústní prezentace)</li><li>21. dubna 2026 – Odeslání rozhodnutí o přijetí (ústní prezentace)</li><li>15. května 2026 – Uzávěrka registrace a platby za zvýhodněnou cenu &amp; registrace autorů (ústní prezentace)</li><li>1. června 2026 – Zveřejnění předběžného detailního programu</li><li>1. června 2026 – Uzávěrka podávání abstraktů (postery)</li><li>16. června 2026 – Odeslání rozhodnutí o přijetí (postery)<ul><li>Autoři, kteří podají abstrakt s preferencí posteru do 5. května 2026, budou o výsledku informováni do 12. května 2026 a budou mít možnost využít zvýhodněnou registraci do 15. května 2026.</li></ul></li><li>30. června 2026 – Uzávěrka registrace autorů (postery)</li><li>30. července 2026 – Uzávěrka podávání abstraktů (pozdní postery – late-breaking)<ul><li>bez možnosti soutěžit o cenu za nejlepší poster</li></ul></li><li>11. srpna 2026 – Odeslání rozhodnutí o přijetí (pozdní postery)</li><li>18. srpna 2026 – Uzávěrka registrace autorů (pozdní postery)</li><li>25. srpna 2026 – Uzávěrka pozdní registrace a platby</li><li>6.–10. září 2026 – Konání sympozia</li></ul><h3>Registrace</h3><blockquote>👉 <a target="_blank" rel="noopener noreferrer" href="https://www.czech-in.org/cmPortalV15/Account/Login?ReturnUrl=%2FcmPortalV15%2FPortal%2FISC26%2Fnormal">Zaregistrujte se na ISC 2026</a></blockquote><h3>Podávání abstraktů</h3><blockquote><a target="_blank" rel="noopener noreferrer" href="https://www.czech-in.org/cmPortalV15/Account/Login?ReturnUrl=%2FcmPortalV15%2FPortal%2FISC26%2Fnormal">👉 Nahrajte svůj abstrakt zde</a></blockquote><h3>VĚDECKÝ PROGRAM - KRÁTKÉ KURZY</h3><h4>SC 6 – Statistická analýza a vizualizace kvantitativních LC/MS dat v softwaru R</h4>🗓️ Neděle, 6. září 2026 🕗 12:30–15:45Rozsáhlé metabolomické a lipidomické studie založené na kapalinové chromatografii ve spojení s hmotnostní spektrometrií (LC/MS) generují komplexní datové soubory. Jejich důkladná statistická analýza a přehledná vizualizace jsou klíčové pro odhalení biologicky významných změn mezi experimentálními podmínkami.Tento krátký kurz nabízí strukturovaný úvod do statistické analýzy dat a jejich vizualizace v prostředí R a poskytuje účastníkům pevný základ pro další samostatné studium. Kurz začíná instalací a nastavením R a RStudio, pokračuje importem dat, jejich úpravou (data wrangling), imputací chybějících hodnot, transformací a škálováním, výpočtem základních deskriptivních statistik a vizualizací pomocí box plotů.Účastníci se dále seznámí s univariačními statistickými přístupy (t-test, ANOVA, post-hoc testy) i s multivariačními metodami, například analýzou hlavních komponent (PCA). Součástí kurzu bude praktická práce s často používanými knihovnami v R, jako jsou tidyverse, rstatix, ggstatsplot, tidyplots, FactoMineR, mixOmics a základní funkce base R.Na konci kurzu budou účastníci vybaveni základními nástroji pro provádění statistických analýz a tvorbu jednoduchých, publikačně připravených vizualizací metabolomických a lipidomických dat.<h4>Lektor</h4><h5>Jakub Idkowiak</h5>Jakub Idkowiak získal titul Ph.D. v oboru analytické chemie na Univerzitě Pardubice pod vedením profesora Michala Holčapka, kde se zaměřoval na hmotnostní spektrometrii lipidů a jejich kvantifikaci v biologických matricích.V současnosti působí jako výzkumný pracovník v Laboratory of Lipid Metabolism and Cancer na KU Leuven (Belgie), vedené profesorem Johannesem Swinnenem. Jeho výzkum se zaměřuje na vývoj analytických metod pro detekci a kvantifikaci lipidů pomocí přímé infuze do hmotnostního spektrometru, zobrazovací hmotnostní spektrometrie a LC–MS. Zajímá se také o statistickou analýzu dat, jejich vizualizaci a využití -omics technologií při studiu metabolismu lipidů u nádorových onemocnění.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/ISC_2026_Jakub_Idkowiak_50a7d3b7b7.jpg" alt="ISC 2026: Jakub Idkowiak" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_ISC_2026_Jakub_Idkowiak_50a7d3b7b7.jpg 156w," sizes="100vw" width="500" height="500">

ISC 2026 – Krátký kurz 6: Statistická analýza a vizualizace kvantitativních LC/MS dat v softwaru R

Už přes dvacet let se Peter Kollár zabývá experimentální farmakologií a mechanismy účinků studovaných látek. Proděkan Farmaceutické fakulty Masarykovy univerzity se svým týmem aktuálně hledá možnosti zesílení účinků protinádorové imunoterapie v kombinaci s jinými látkami.<h4>Proč vás kdysi zlákala právě oblast experimentální farmakologie?</h4>Farmakologie mě ze všech předmětů na fakultě bavila nejvíc. Moji vědecko-výzkumnou práci ale zásadně formoval pobyt na Institutu farmakologického výzkumu Mario Negri v Miláně, kam jsem se dostal při doktorském studiu v letech 2001 až 2002. Tam jsem patřil do skupiny, která se – pro mě nově – věnovala experimentální farmakologii na buněčných liniích se zaměřením na oblast nádorových onemocnění. Po návratu se mi podařilo realizovat projekt na vybudování vůbec první laboratoře pro buněčné kultury na Farmaceutické fakultě Veterinární a farmaceutické univerzity, která začala fungovat v roce 2006.<blockquote>„Od začátku jsem se ve své laboratoři věnoval dvěma směrům, zkoumání účinků látek přírodního původu a látkám nově syntetizovaným.“</blockquote><h4>Jaký výzkum jste tam tehdy realizoval?</h4>Navazoval jsem na svoje zkušenosti z pobytu v Itálii z oblasti výzkumu látek s potenciálním protinádorovým působením. Od začátku jsem se ve své laboratoři věnoval dvěma směrům, zkoumání účinků látek přírodního původu a látkám nově syntetizovaným. Začal jsem v tomto spolupracovat s kolegy ze dvou ústavů naší fakulty: Ústavu přírodních léčiv a Ústavu chemických léčiv. Karel Šmejkal mi dokázal vytipovat látky přírodního původu, které by mohly mít zajímavé účinky v rámci protinádorové aktivity. Nejdelší dobu jsem se pak věnoval látkám ze dvou rostlin – morušovníku bílého (Morus alba) a pavlovnie plstnaté (Paulownia tomentosa).<h4>Jaké konkrétní účinky jste u těchto látek zkoumali?</h4>Na začátku jsme studovali převážně jejich schopnost zastavovat proliferaci u nádorových buněčných linií a ovlivňovat průběh buněčného cyklu. Látky pocházející z rostliny pavlovnie nás provázejí v našem výzkumu asi nejdelší dobu. Nejnověji zkoumáme jejich účinky v úplně nové oblasti, a to v kombinaci s již existujícími protinádorovými léčivy. Konkrétně se soustředíme na skupinu léčiv protinádorové imunoterapie.<h4>Proč právě tato léčiva?</h4>Jedná se o jeden z průlomových přístupů k léčbě nádorových onemocnění. Nicméně má i svá úskalí, mimo jiné na ně například může vzniknout rezistence a nejsou potom dostatečně účinná. Naším cílem je prozkoumat, jak by mohla tato léčiva na molekulární úrovni interagovat s jinými látkami, čímž by mohlo potenciálně dojít ke zvýšení účinku takových léčiv. Náš výzkum naznačuje, že některé látky přírodního původu by mohly mít uvedený potenciál. Samozřejmě jde jen o začátek hledání možného budoucího využití těchto vlastností. Naší ambicí není objevit přímo lék na rakovinu, ale rádi bychom otevírali nové cesty k dalšímu výzkumu.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Radek_Mica_Vyzkumny_tym_zleva_Jana_Melicharova_Martina_Cudova_Tereza_Kauerova_a_Peter_Kollar_b3752c14be.jpg" alt="Radek Miča: Výzkumný tým (zleva): Jana Melicharová, Martina Čudová, Tereza Kauerová a Peter Kollár" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Radek_Mica_Vyzkumny_tym_zleva_Jana_Melicharova_Martina_Cudova_Tereza_Kauerova_a_Peter_Kollar_b3752c14be.jpg 234w," sizes="100vw" width="870" height="580"><h4>Co vás k této oblasti přivedlo?</h4>Paradoxně to byl druhý směr, kterému se v naší laboratoři věnujeme, a to výzkum syntetických látek, které mají mimo jiné schopnost inhibovat signální dráhu STAT3. Ta je u řady nádorových buněk často nadměrně aktivována a pomáhá jim v růstu a přežití, čímž se stává zajímavým cílem pro budoucí protinádorová léčiva. Toto nám otevřelo i další cesty výzkumu, například oblast takzvaného drug repurposingu, kdy se u již existujících a schválených léčiv zkoumají možné jiné indikace a nová terapeutická využití. Existují totiž například léčiva používaná na léčbu jiných onemocnění než nádorových, u kterých byla objevena schopnost inhibovat dráhu STAT3, a my se věnujeme studiu jejich účinku vůči nádorovým buněčným liniím....

Naší ambicí není objevit lék na rakovinu, ale otevírat nové cesty výzkumu

V týdnu od 9. března na Vás čekají v oblasti kapalné fáze a především HPLC a LC/MS následující webináře.<blockquote><h4><a target="_blank" rel="noopener noreferrer" href="https://www.lcms.cz/webinars">👉 DETAILY A REGISTRACE V SEKCI WEBINÁŘE</a></h4></blockquote><blockquote>👉 Vyhledávejte a filtrujte v největší globální databázi s více než 5 500 GC, HPLC, MS a spektroskopickými webináři.</blockquote><h5>1. Agilent Technologies: Simplifying Liquid Chromatography Applications for Petrochemical Products by the New Agilent Infinity III LC Series Technology</h5><ul><li>Út, 10. 3. 2026 10:00 CET</li><li><a target="_blank" rel="noopener noreferrer" href="https://lcms.cz/webinar/5986">Registrace</a></li></ul>Jak řada Infinity III LC zjednodušuje HPLC workflow pro petrochemické produkty a podporuje metody ASTM díky robustnímu výkonu.<h5>2. Thermo Fisher Scientific: IC Nitrite Analysis: Streamlined Workflows for Reliable Quantification</h5><ul><li>Út, 10. 3. 2026 12:00 CET</li><li><a target="_blank" rel="noopener noreferrer" href="https://lcms.cz/webinar/5982">Registrace</a></li></ul>Iontová chromatografie pro kvantifikaci dusitanů ve vodě, pomocných látkách a farmaceutických produktech.<h5>3. SelectScience: Supercharge LNP EE% and Size Characterization on Stunner AF</h5><ul><li>Út, 10. 3. 2026 17:00 CET</li><li><a target="_blank" rel="noopener noreferrer" href="https://lcms.cz/webinar/5988">Registrace</a></li></ul>Jednoinstrumentální workflow pro měření velikosti LNP a účinnosti zapouzdření RNA/pDNA bez použití surfaktantů.<h5>4. Thermo Fisher Scientific: Optimizing Every Step: An End-to-End Workflow for High-Confidence Single-Cell Proteomics</h5><ul><li>Út, 10. 3. 2026 19:00 CET</li><li><a target="_blank" rel="noopener noreferrer" href="https://lcms.cz/webinar/5949">Registrace</a></li></ul>Kompletní workflow proteomiky jednotlivých buněk od přípravy vzorků po LC-MS a analýzu dat.<h5>5. C&amp;EN: Explode into AI-driven Automation with Stuntman</h5><ul><li>St, 11. 3. 2026 16:00 CET</li><li><a target="_blank" rel="noopener noreferrer" href="https://lcms.cz/webinar/5989">Registrace</a></li></ul>AI platforma pro automatizaci experimentů od návrhu až po opakování v jedné integrované laboratorní infrastruktuře.<h5>6. Thermo Fisher Scientific: Real-World Breakthroughs: Expert-Led Applications in Single-Cell Proteomics</h5><ul><li>St, 11. 3. 2026 19:00 CET</li><li><a target="_blank" rel="noopener noreferrer" href="https://lcms.cz/webinar/5950">Registrace</a></li></ul>Případové studie a praktické strategie pro maximalizaci kvality dat v proteomice jednotlivých buněk.<h5>7. Agilent Technologies: Automation at the Next Level: Never Lose Track of Your Sample</h5><ul><li>Čt, 12. 3. 2026 06:30 CET</li><li><a target="_blank" rel="noopener noreferrer" href="https://lcms.cz/webinar/5965">Registrace</a></li></ul>Digitální řízení workflow a plná automatizace správy vzorků v moderní laboratoři.<h5>8. Agilent Technologies: Veterinary Drugs Edition</h5><ul><li>Čt, 12. 3. 2026 08:30 CET</li><li><a target="_blank" rel="noopener noreferrer" href="https://lcms.cz/webinar/5954">Registrace</a></li></ul>Strategie LC-MS/MS pro monitorování reziduí veterinárních léčiv v potravinách podle Codex, EU a FSSAI.<h5>9. Agilent Technologies: Improve Your NGS Workflow With The Magnis</h5><ul><li>Čt, 12. 3. 2026 14:00 CET</li><li><a target="_blank" rel="noopener noreferrer" href="https://lcms.cz/webinar/6010">Registrace</a></li></ul>Automatizovaná příprava NGS knihoven pomocí systému Magnis v klinické diagnostice.<h5>10. Waters Corporation: PFAS in the Environment: A Deep Dive into Analysis, Regulation, and Real-World Data</h5><ul><li>Čt, 12. 3. 2026 15:00 CET</li><li><a target="_blank" rel="noopener noreferrer" href="https://lcms.cz/webinar/5920">Registrace</a></li></ul>Analýza PFAS v kontextu regulací a environmentálních dat podle aktualizované rámcové směrnice EU o vodě.<h5>11. Thermo Fisher Scientific: Optimizing for Impact: Expert Strategies for Single-Cell Preparation and Data Analysis</h5><ul><li>Čt, 12. 3. 2026 19:00 CET</li><li><a target="_blank" rel="noopener noreferrer" href="https://lcms.cz/webinar/5951">Registrace</a></li></ul>Strategie přípravy vzorků a analýzy dat pro pokročilou proteomiku jednotlivých buněk.<h5>12. Agilent Technologies: Comprehensive Workflow for Automated Sample Cleanup and Sensitive Quantitation of GLP-1 Analogs from Plasma</h5><ul><li>Čt, 12. 3. 2026 19:00 CET</li><li><a target="_blank" rel="noopener noreferrer" href="https://lcms.cz/webinar/5815">Registrace</a></li></ul>Automatizovaný LC/MS workflow pro citlivou kvantifikaci analogů GLP-1 v plazmě bez použití protilátek.<h5>13. Agilent Technologies: Development of Long-Read Sequencing Methods Leveraging Target Enrichment</h5><ul><li>Pá, 13. 3. 2026 08:30 CET</li><li><a target="_blank" rel="noopener noreferrer" href="https://lcms.cz/webinar/5953">Registrace</a></li></ul>Pokročilé metody sekvenování dlouhých fragmentů pro analýzu metylace DNA a cDNA v plné délce.<h5>14. Agilent Technologies: Designing Integrated Analytical Workflows for GLP-1 and Peptide Therapeutics</h5><ul><li>Pá, 13. 3. 2026 11:00 CET</li><li><a target="_blank" rel="noopener noreferrer" href="https://lcms.cz/webinar/5943">Registrace</a></li></ul>Integrované LC-MS a informatické workflow pro vývoj a kontrolu terapeutik GLP-1 a peptidů.<h5>15. SCIEX: Extractables and Leachables: The Complete Workflow Using the SCIEX X500R QTOF System</h5><ul><li>Pá, 13. 3. 2026 15:00 CET</li><li><a target="_blank" rel="noopener noreferrer" href="https://lcms.cz/webinar/5991">Registrace</a></li></ul>Kompletní workflow pro analýzu extrahovatelných a vyluhovatelných látek pomocí systému X500R QTOF.

Webináře LabRulezLCMS týden 11/2026

Webináře

Osobnosti

Věda a výzkum

Článek

Video

Nejbližší akce

Celostátní webový portál a elektronický časopis Universitas o vědě, vzdělávání, výzkumu a vysokém školství je společným projektem 22 českých veřejných vysokých škol.

Universitas

Vše ze světa analytické chemie na jednom místě. Propojujeme lidi při řešení jejich problémů. U nás naleznete všechny potřebné informace snadno, rychle a přehledně. Přestaňte hledat a začněte nacházet.

LabRulez

Mezinárodní sympozium o chromatografii (ISC) představuje nejstarší sérii konferencí zaměřených na separační vědu. Sympozia ISC se pořádají od roku 1956 každý sudý rok. ISC je mezinárodně uznávanou sérií setkání, na nichž se diskutuje o všech typech chromatografie a separační vědy s širokým pokrytím technik a aplikací.

International Symposium on Chromatography - (ISC)

Agilent Technologies

Thermo Fisher Scientific

SelectScience

C&EN

Waters Corporation

In recent years, glucagon-like peptide-1 receptor (GLP-1R) agonists have gained significant attention because of their effectiveness to treat obesity and type 2 diabetes. The global market for GLP-1 analogues is projected to grow rapidly, reaching $260 billion by 2034. Developing sensitive bioanalytical assays to determine pharmacokinetics and toxicokinetics is crucial for advancing these medications.&nbsp;Traditionally, the plasma concentration of GLP-1 analogs was measured by ligand binding assay, which requires time to develop antibody and lack selectivity and specificity. Liquid chromatography-mass spectrometry (LC/MS), which is used for sequence identification of GLP-1 receptor agonists, has emerged as an alternative methodology to precise quantify these molecules in biological matrix because of its superior sensitivity, wide dynamic range, and high specificity. Here we present an automated workflow, which combines automation and LC/MS technologies, to quantify GLP-1 analog drug in human plasma by using an Agilent 1290 Infinity II Bio LC and an Agilent 6495D triple quadrupole system (Figure 1). Our results indicate that this automated LC/MS workflow can enhance assay sensitivity by five times compared to traditional organic solvent precipitation.&nbsp;This workflow can be used for quantitative analysis of GLP-1 therapeutics without the need to have specific antibody while providing excellent sensitivity, high specificity and fast method development, which will play a crucial role in drug discovery and development.<blockquote>Presenter: Xi Qiu, PhD (LC-MS Application Scientist, Agilent Technologies, Inc.)Xi Qiu is application scientist at Agilent, he has extensive experience using LC-MS for large molecules analysis including protein, protein conjugates, peptide, and oligos. He earned his Ph.D. degree from the department of Pharmacognosy and Medicinal Chemistry at University of Illinois at Chicago focusing on benefits and safety of botanical dietary supplements and herbal-drug interactions. After graduation, he did his postdoc training at Pfizer and Bristol Myers Squibb where he worked on drug transporters protein expression analysis in tissues as well as drug induced liver injury mechanism. He then worked for two major contract research organizations leading their large molecule LC-MS group performing protein, protein conjugates, peptide, and oligos pharmacokinetics/toxicokinetics analysis under GLP/regulated environment. Prior to joining Agilent, he worked at Johnson and Johnson where he focused on large molecule quantification using LC-MS at intact and peptide level.</blockquote>

Agilent Technologies: Comprehensive workflow for Automated Sample Cleanup and Sensitive Quantitation of Glucagon-like peptide-1 (GLP-1) Analogs from Plasma

Comprehensive workflow for Automated Sample Cleanup and Sensitive Quantitation of Glucagon-like peptide-1 (GLP-1) Analogs from Plasma

Discover automated LC/MS approach for GLP-1 bioanalysis with Agilent, delivering higher sensitivity, specificity, and assay development without antibodies.

Automated Sample Cleanup & Sensitive Quantitation of GLP-1

<div><h4>Navigating Challenges and Opportunities for Environmental Testing Labs Under the Revised EU Water Framework Directive</h4>The European Commission’s proposed updates to the Water Framework, Groundwater, and Environmental Quality Standards Directives are bringing new responsibilities and opportunities for environmental testing labs. With expanded pollutant lists - including PFAS, pharmaceuticals, and pesticide metabolites - and stricter monitoring and reporting requirements, the landscape of water analysis is rapidly evolving.Join the 4th Waters Environmental Webinar Series to explore how your lab can navigate these challenges and turn regulatory change into opportunity.Register for free and partner with us to shape the future of European water quality.<h5>Why Attend</h5>Stay ahead of new EU regulatory demands with insights from leading experts. Gain practical guidance, share experiences with peers, and prepare your lab for the next generation of water quality standards.<h5>Highlights</h5><ul><li>New pollutant categories and analytical challenges</li><li>Updates to monitoring protocols and reporting</li><li>Innovative methods to meet revised Environmental Quality Standards</li><li>Strategic guidance for compliance and adaptation</li></ul>Lead the change in water analysis—stay ahead, stay compliant, and make a real impact.<h4>EPISODE 2: PFAS in the Environment: A Deep Dive into Analysis, Regulation, and Real-World Data</h4><h4>What you Will Learn</h4><ul><li>How to maintain sub-ng/L LOQs in water samples with direct injection</li><li>How an extended number of PFAS and Relevant Potency Factors in the upcoming EU Water Framework Directive can be addressed</li></ul><blockquote>Presenter: Jana Kováčová (PFAS Lead for Continental Europe, ALS Czech Republic)Jana Kováčová is an analytical chemist with over 15 years of experience in method development and validation. She earned her MSc and PhD from the University of Chemistry and Technology, Prague (UCT Prague), where she specialized in analytical methods for pesticide residue determination in water and food matrices of both plant and animal origin.In 2020, Jana joined ALS Czech Republic as a Validation Specialist within the environmental analytical innovations group, later transitioning to a full-time focus on PFAS (per- and polyfluoroalkyl substances) analytics. In 2022, she was appointed Supervisor of the PFAS Section.Currently, Jana serves as the PFAS Lead for Continental Europe. In this role, she coordinates ALS’s PFAS analytical activities across the region, acting as a key technical representative for PFAS topics. She supports laboratories and clients with strategic guidance and data interpretation, aligns testing approaches across multiple sites, and ensures consistent, high-quality delivery. To stay at the forefront of the field, Jana closely monitors legislative updates and emerging trends, sharing her expertise through client webinars, seminars, and presentations at scientific conferencesPresenter: Sara Beverly (Principal Sales Application Chemist, Waters)In her current position, Sara is a Principal Sales Application Chemist specializing in food and environmental LC-MS/MS based applications within the Waters UK and Ireland demo laboratory. Sara has worked in F&amp;E analysis with various research interests including the development of both multi-residue HRMS screening and targeted LC/GC MS based methods for the past 25 years in both the government and private sectors. Prior to joining Waters Sara was employed as a Lead Scientist at the Food and Environment Research Agency (FERA, Defra, UK) for 14 years. Sara has participated in EU Food and Veterinary Office (FVO) audit inspections, was an expert on behalf of the International Atomic Energy Agency (IAEA) and a member of the EuroResidue conference scientific committee.Presenter: Claudia Rathmann (Principal F&amp;E Market Development Manager, Waters Corporation)Experienced and passionate analytical science professional with over 20 years of technical and strategic expertise in food and environmental applications. Currently serving as Principal Market Development Manager at Waters Corporation, Claudia specializes in connecting customers with product management to deliver innovative solutions for complex analytical challenges. With a strong scientific foundation and a proven track record in both technical and marketing roles, Claudia bridges the gap between customer needs and product innovation across the EMEA region.</blockquote></div>

PFAS in the Environment: A Deep Dive into Analysis, Regulation, and Real-World Data

Explore PFAS analysis, regulation, and real-world data under the revised EU Water Framework Directive in Episode 2 of the Waters Environmental Webinar Series.

PFAS in Environment: Analysis, Regulation

Join us for Part 1 of our three-part Single-Cell Proteomics Webinar Series, designed to guide researchers through the technologies, workflows, and analytical strategies enabling deeper biological insights at single cell resolution. This introductory session provides a comprehensive overview of the end-to-end workflow and establishes the foundation for the more advanced topics that will follow in subsequent webinars.In this session, we will walk through the complete single-cell proteomics workflow, from initial sample preparation to liquid chromatography, mass spectrometry, and data analysis. Attendees will see how each component contributes to data quality, sensitivity, and scalability, and how Thermo Fisher Scientific’s integrated portfolio is purpose-built to support high-confidence single-cell protein quantification.<h4>Why attend?</h4>Participants will gain a clear understanding of:<ul><li>How each step in the workflow influences overall data quality and biological interpretation.</li><li>The latest technologies and best practices for generating reproducible, high-sensitivity single-cell proteomics data.</li><li>How Thermo Fisher Scientific’s tools work together seamlessly to deliver actionable insights.</li></ul>The session will conclude with a live Q&amp;A, providing participants the opportunity to engage directly with the speaker.Whether you are establishing a single-cell proteomics workflow for the first time or looking to optimize an existing platform, this foundational session will equip you with the knowledge needed to navigate the full process with confidence.<blockquote>Presenter: Bernard Delanghe (Scientific Lead, Proteomics Workflow Applications, Thermo Fisher Scientific)Bernard Delanghe specializes in single-cell proteomics workflows, bringing together advanced mass spectrometry and data analysis approaches. With over 20 years of experience in mass spectrometry and bioinformatics, Bernard is based in Bremen, Germany and has held multiple leadership roles across proteomics hardware and software. He was recognized with the 2018 European Proteomics Association Industry Award for his contributions to Thermo Scientific™ Proteome Discoverer™ software.</blockquote>

Thermo Fisher Scientific: Single-cell proteomics

Optimizing Every Step: An End-to-End Workflow for High-Confidence Single-Cell Proteomics

Single-cell proteomics webinar: end-to-end workflow from sample prep to LC-MS and data analysis using Thermo Fisher Scientific solutions. Live Q&A included.

Workflow for High-Confidence Single-Cell Proteomics

In Part 2 of our three-part Single-Cell Proteomics Master Class Series, we move beyond foundational workflows to explore real-world applications led by experts actively advancing the field. Featuring Ryan Kelly, PhD (Brigham Young University) and Sarah Sipe, PhD (Parallel Squared Technology Institute), this session highlights how single-cell proteomics is being applied in practice to address complex biological questions.Drawing from their own research and facility experience, our guest speakers will share practical case studies, challenges, and strategies for maximizing data quality, throughput, and biological insight—providing attendees with actionable takeaways they can apply immediately.<h4>Why attend?</h4>Participants will walk away with:<ul><li>A clearer picture of real-world challenges and solutions when implementing single-cell proteomics.</li><li>Proven strategies used by experts to maximize data quality, throughput, and interpretation.</li><li>Inspiring examples of how single-cell proteomics is enabling breakthroughs in biology and disease research.</li><li>Practical takeaways that can be applied immediately in your own lab or workflow development.</li><li>An opportunity to engage with the experts in a live Q&amp;A.</li></ul>Whether you are preparing to launch a single-cell proteomics program or looking for ways to accelerate ongoing studies, this session provides actionable knowledge from researchers who are already driving innovation in the field.<blockquote>Presenter: Ryan Kelly, PhD (Professor, Brigham Young University)Ryan Kelly is a professor in the Department of Chemistry and Biochemistry at Brigham Young University. His recent research efforts have focused on single-cell and spatial proteomics, which have involved tailoring sample preparation, separations, ionization and mass spectrometry acquisition for low-input samples.Presenter:&nbsp;Sarah Sipe, PhD (Head of Mass Spectrometry, Parallel Squared Technology Institute)Sarah is a mass spectrometrist with 10 years of experience spanning analysis of primary explosives and drugs to proteins and viruses. Now, Sarah is the Head of Mass Spectrometry at Parallel Squared Technology Institute, where she is pushing the limits of current technologies for total characterization of the single cell proteome.Moderator: Bernard Delanghe (Scientific Lead, Proteomics Workflow Applications, Thermo Fisher Scientific)Bernard Delanghe specializes in single-cell proteomics workflows, bringing together advanced mass spectrometry and data analysis approaches. With over 20 years of experience in mass spectrometry and bioinformatics, Bernard is based in Bremen, Germany and has held multiple leadership roles across proteomics hardware and software. He was recognized with the 2018 European Proteomics Association Industry Award for his contributions to Thermo Scientific™ Proteome Discoverer™ software.</blockquote>

Real-World Breakthroughs: Expert-Led Applications in Single-Cell Proteomics

Single-cell proteomics webinar Part 2: real-world case studies, expert strategies and practical tips to improve data quality, throughput and biological insight.

Expert-Led Applications in Single-Cell Proteomics

In Part 3, the final webinar of our Single-Cell Proteomics Master Class Series, we turn foundational knowledge and real-world applications into practical, lab-ready strategies. This final session focuses on the critical steps that determine success in single-cell proteomics workflows—sample preparation and high-quality data analysis.Attendees will gain actionable guidance from experts, including our partner Cellenion, who will share best practices for achieving reliable, reproducible single-cell sample preparation. You will also explore how to leverage Thermo Scientific™ Proteome Discoverer™ software to extract deeper insights, streamline data interpretation, and enhance confidence in your results.<h4>Why attend?</h4>Participants will learn how to:<ul><li>Apply proven sample preparation practices to increase workflow robustness and data quality.</li><li>Reduce sources of variability and ensure consistency across single-cell experiments.</li><li>Use Proteome Discoverer software to reveal more meaningful biological insights from complex datasets.</li><li>Integrate lessons from all three webinars to build or refine a high-performing single-cell proteomics pipeline.</li></ul>You will also have the opportunity to ask the experts your questions during the live Q&amp;A.Whether you are refining an established workflow or preparing to scale your single-cell proteomics efforts, this session delivers the practical expertise needed to achieve reliable, high-impact results.<blockquote>Presenter: Anjali Seth, PhD (Head of Single Cell Proteomics, Cellenion)Anjali Seth leads Single Cell Proteomics at Cellenion. She holds a Master’s from ENS Paris and a PhD from Pierre &amp; Marie Curie University on magnetic nanoparticles for drug delivery. After postdoctoral work in Oxford and Lyon, she joined Cellenion in 2019, advancing single-cell proteomics workflows for mass spectrometry.Presenter:&nbsp;Philip Loziuk PhD (Product Manager, Chromatography and Mass Spectrometry Division, Thermo Fisher Scientific)Phil has spent 8 years at Thermo Fisher Scientific, driving innovation in proteomics. As Product Manager for Proteome Discoverer, he shapes the software’s vision and impact. Previously, he supported scientists globally as a Field Application Scientist and provided expert product support for the Tribrid platform.Moderator: Bernard Delanghe (Scientific Lead, Proteomics Workflow Applications, Thermo Fisher Scientific)Bernard Delanghe specializes in single-cell proteomics workflows, bringing together advanced mass spectrometry and data analysis approaches. With over 20 years of experience in mass spectrometry and bioinformatics, Bernard is based in Bremen, Germany and has held multiple leadership roles across proteomics hardware and software. He was recognized with the 2018 European Proteomics Association Industry Award for his contributions to Thermo Scientific™ Proteome Discoverer™ software.</blockquote>

Optimizing for Impact: Expert Strategies for Single-Cell Preparation and Data Analysis

Single-cell proteomics webinar: practical sample prep strategies, data analysis with Proteome Discoverer and expert tips for robust, reproducible workflows.

Strategies for Single-Cell Preparation and Data Analysis

<h4>Food Safety Webinar Series: When Food Meets the Lab</h4>Food testing in the region still revolves around “legacy” contaminants that decide release, rejection, and recall discussions - veterinary drug residues, pesticide residues and fumigants, and toxic elements including species-sensitive forms, in different food matrices. This 3-part series is built for audiences where regulatory expectations reference Codex-based frameworks, country-specific legislative guidelines, and import/export-market requirements that influence testing scope, reporting limits, and confirmation criteria. Each webinar focuses on the analytical factors that drive outcomes: matrix effects and co-extractives, trace-level quantitation, transition/ion-ratio checks, interference control, and reportable result logic.Keynote expert speakers will set the regulatory context, give a glimpse of the current trends, and future implications. Agilent workflow segments map these needs to sample preparation nuances, LC-MS/MS for multi-class residues, GC-MS/MS and headspace GC for residue/fumigant markers, and ICP-MS plus LC-ICP-MS for heavy metals and speciation, including QC structures and data review patterns used in high-throughput labs, to name a few.<h5>Webinar Series Details</h5><ul><li>Register once to attend the complete 3-part series</li><li>Submit your questions beforehand</li><li>Access recorded sessions anytime within one year</li><li>Certificate of attendance will be provided to all attendees</li></ul><h4>Part 1: Veterinary Drugs Edition</h4>Veterinary drug residue monitoring increasingly demands broad coverage across classes (β-lactams, sulfonamides, tetracyclines, quinolones, macrolides, nitroimidazoles, chloramphenicol-type compounds and others) at low reporting levels in seafood, dairy and meat matrices. Regulatory context spans Codex-oriented residue frameworks and national controls such as residue provisions under EU and FSSAI, with additional buyer-driven lists and decision rules influencing what labs must report. This session also focuses on the LC-MS/MS methods for multi-class screening and confirmation.<blockquote>Presenter: Dr. Niladri Sekhar Chatterjee (Senior Scientist, ICAR-CIFT, Kochi, India)Presenter:&nbsp;Dr. Prasanth Joseph (Application Engineer, LC/MS, Agilent Technologies, India)</blockquote>

Agilent Technologies: Food Safety Webinar Series: When Food Meets the Lab

Veterinary Drugs Edition

Veterinary drug residues webinar: LC-MS/MS screening and confirmation in seafood, dairy and meat under Codex, EU and FSSAI regulations.

The end-to-end sample journey represents a structured and traceable pathway that ensures every sample is managed with accuracy, integrity, and compliance from the moment an analysis request is raised to the secure archival of data. This comprehensive approach enables laboratories to deliver reliable results while maintaining operational efficiency and regulatory confidence.<h4>Why is this webinar a must‑attend?</h4>Join us for this insightful webinar where you’ll explore essential elements of the Digital &amp; Automated Lab, including:<ul><li>Efficient management of analysis requests and sample registration, integrated with inventory management.</li><li>Streamlined processes for sample receipt and verification.</li><li>Automation in sample preparation and end‑to‑end sample tracking within chromatography workflows.</li><li>Comprehensive data handling from acquisition and review to reporting, storage, and archiving.</li></ul>By overseeing the sample journey from the initial analysis request through to final archival, you ensure complete traceability, stronger data integrity, and improved operational performance. This structured lifecycle not only reinforces compliance and quality standards but also builds stakeholder confidence by guaranteeing that every sample is handled with accuracy and accountability.Register now and learn how to turn your scattered digital lab workflows into a connected, holistic, and automated lab ecosystem.<blockquote>Presenter: Dr. Nirmal Thakker (Technical Application Support Specialist - Chromatography, Dissolution &amp; Lab Informatics, Agilent Technologies)Dr. Nirmal has done his PhD in quality assurance and pharmacy and his master's in pharmacy from the University of Pune. He has more than 15 years of overall industrial experience working in analytical research &amp; development for renowned multinational pharma companies like Glenmark, Torrent, and Piramal. He has also worked with Spinco Biotech as an application specialist for LC. Presently, he is working with Agilent Technologies as a technical application support specialist for chromatography, dissolution, and lab informatics. He has expertise in chromatography, QbD, method transfer, and mass spectrometry.Presenter: Mr. Amit Ghate (Application Specialist - Lab Informatics, Agilent Technologies)Amit Ghate is currently working as Lab Informatics Application Specialist at Agilent Technologies. Amit comes from analytical software background where he has an in-depth knowledge of variety of software like Chromatography Data Systems, Data Management, LIMS, Electronic Lab Notebook, databases, reports and Compliance. Prior to joining Agilent, Amit worked with Persistent Systems Ltd as a Project Manager for software support and services. He has done his Masters in Bioinformatics from University of Pune. His main areas of interest is in providing workflow solutions and enabling digital transformation of labs.</blockquote>

Agilent Technologies: Automation at the Next Level: Never Lose Track of Your Sample

Automation at the Next Level: Never Lose Track of Your Sample

Webinar on digital lab automation, covering end-to-end sample tracking, chromatography workflows, data integrity, and compliance.

Automation: Never Lose Track of Your Sample

Lipid nanoparticle (LNP) payloads are the top choice when it comes to delivering a wide range of nucleic acid therapeutics, like RNA and plasmid DNA (pDNA). But when it comes to characterizing LNPs, assays for size, payload quantification and encapsulation efficiency (EE%) are split up in different steps that slow down any workflow. This split‑assay approach adds complexity, from increased pipetting steps to surfactants that alter pDNA structure and reduce reproducibility and sample throughput. As LNP programs scale up, researchers need simpler, faster LNP characterization in an EE% method that works with any nucleic acid payload.In this SelectScience® webinar, Dr. Kevin Lance, Director of Product Management at Unchained Labs, will present new data showing how Stunner AF measures EE% for both RNA‑ and pDNA‑containing LNPs without surfactants, and will demonstrate how avoiding surfactant‑driven particle disruption creates a platform EE% assay that also allows simultaneous reads on size and aggregation from the same measurement. You will learn how to integrate Stunner AF into RNA‑ and pDNA‑LNP screening, formulation optimization, and QC workflows to capture more LNP data in far less time.<h4>Key learning objectives:</h4><ul><li>Learn how to characterize size, payload amount, and encapsulation efficiency in a single, one-instrument assay.</li><li>Understand the challenges with pDNA payloads and what steps to take to overcome them.</li><li>Explore the challenges and latest approaches in UV/Vis quantification of LNPs and their payloads.</li><li>Understand how surfactant‑free EE% measurements preserve particle integrity for both RNA‑ and pDNA‑LNPs.</li><li>Learn how to streamline high‑throughput LNP screening with up to 44 samples plus standards on a single 96‑well plate.</li></ul><h4>Who should attend?</h4><ul><li>Formulation and analytical scientists developing and optimizing biologic drug products – including conjugated LNPs, novel formulations, stability studies, excipient screening, and biophysical characterization.</li><li>Process development teams translating early formulations into scalable, manufacturable processes.</li></ul><h4>Certificate of attendance</h4>If you attend the live webinar, you will automatically receive a certificate of attendance, including a learning outcomes summary, for continuing education purposes.If you view the on-demand webinar, you can request a certificate of attendance by emailing editor@selectscience.net.<h4>Webinar details</h4><ul><li>Cost: Free to attend</li><li>Location: Online</li><li>Duration: 60 minutes</li></ul>Registration is required to secure your place. If you register but cannot attend live, you will receive a link to the on‑demand recording once it becomes available.<blockquote>Presenter: Dr. Kevin Lance (Director, Product Management, Unchained Labs)Dr. Kevin Lance covers the Stunner portfolio globally at Unchained Labs. His expertise includes biophysical characterization of proteins, nucleic acids, viral vectors, and LNPs. Prior to Unchained Labs, his research experience covered the fields of sustained antibody delivery and nanotechnology. He earned his Ph.D. in Bioengineering from the joint UC Berkeley – UCSF Bioengineering Graduate Program.&nbsp;Moderator: Olivia Long (Editorial Team, SelectScience)</blockquote>

SelectScience: Supercharge LNP EE% and size characterization on Stunner AF

Supercharge LNP EE% and size characterization on Stunner AF

Streamline RNA and pDNA LNP characterization with surfactant-free EE% measurement, size and aggregation in one assay using Stunner AF.

<h4>The Problem</h4>Lab automation promises speed and scale, but too often it operates without intelligence. Researchers must translate scientific intent into rigid workflows, scripts, and parameters — requiring deep expertise and constant manual intervention. As experiments grow more complex, automation becomes harder to adapt, forcing scientists to rely on guesswork and slowing iteration.<h4>The Solution</h4>Stuntman brings native AI into automation to fundamentally change how experiments are run. With built-in intelligence, Stuntman allows researchers to describe their intent in plain language and have experiments designed, executed and analyzed end-to-end. Stuntman creates workflows, runs experiments, logs results, and hands data back for AI-driven interpretation – guiding experiments forward with clarity, adaptability, and purpose.<h4>The Proof</h4>In this webinar, see how Stuntman turns ideas into executable experiments across pharma, biopharma, materials, energy, consumer goods workflows, and more. Learn how Stuntman’s built-in AI enables experiment design, automated execution and rapid iteration — all on a single, integrated platform.<h4>Key Learning Objectives:</h4><ul><li>Understand why traditional lab automation struggles to scale with experimental complexity and where intelligence is missing.</li><li>See how Stuntman embeds native AI into automation workflows to translate scientific intent into executable experiments.</li><li>Learn how a fully integrated platform connects experiment design, execution, data logging, and AI-driven iteration across industries.</li></ul><blockquote>Presenter: Ruja Shrestha (Product Manager, Unchained Labs)Presenter:&nbsp;Sara Kobilka (Contributing Editor, C&amp;EN Media Group)</blockquote>

C&EN: Explode into AI-driven Automation with Stuntman

Explode into AI-driven Automation with Stuntman

AI-powered lab automation with Stuntman—design, execute, and iterate experiments end-to-end on one integrated platform.

<h4>Are you interested in automating your NGS workflow but don’t operate a high throughput laboratory?</h4>Join our upcoming webinar for an introduction to the Agilent Magnis, a fully automated NGS library preparation instrument that processes up to 8 samples per run with minimal hands on time.In the webinar we will share real-life experience using the Agilent Magnis system for automated NGS library preparation in a clinical diagnostics laboratory.After a short introduction to the University Hospital Osijek and its molecular testing activities, the talk outlines the clinical and operational context of routine NGS testing. It will highlight the transition from manual to automated workflows, showing how the Magnis system improves efficiency, reproducibility, standardization, and hands-on time.Practical diagnostic examples demonstrate how Magnis enables reliable and consistent NGS library preparation under real clinical conditions, offering guidance for laboratories considering automation.<h5>What to Expect</h5><ul><li>Product Overview: Our Product Manager will provide a concise introduction to the Magnis system and its capabilities.</li><li>Real World User Experiences: Hear directly from customers who have integrated the Magnis into their workflows.&nbsp;</li><li>How a large laboratory in South Africa increased efficiency and reproducibility.</li><li>How a Molecular Pathology lab in Croatia achieved a smooth and confident start in NGS.</li></ul><blockquote>Presenter: Dr. Martin Judex (Channel Partner Manager DGG, Agilent Technologies)After studying Biology at the University of Regensburg in Germany, Martin earned his PhD at the University Hospital Regensburg, where he focused on gene expression studies in samples from patients with rheumatoid arthritis. He continued this research as a postdoctoral fellow in San Diego, USA, and later in Munich, Germany, before beginning his sales career at Stratagene.When Stratagene was acquired by Agilent, Martin advanced through several sales positions within the company. He currently serves as Channel Partner Manager for Eastern European countries—initially for Genomics, and since 2024 also for Pathology.Presenter:&nbsp;Matt Wang (Product Manager, Agilent Technologies)Matt Wang is a Senior Product Manager at Agilent Technologies, where he drives product strategy for next‑generation sequencing (NGS) automation. He leads system architecture and workflow integration for the Magnis NGS Prep System and oversees its global deployment, including expansion into developing markets and OEM partnerships in Greater China. His expertise spans FDA medical device compliance, clinical LDT verification and validation, and integration of LIMS and cybersecurity requirements.Matt holds an MBA from the University of California, Irvine, and a bachelor’s degree in Bioengineering from the University of California, San Diego.Presenter:&nbsp;Roberto Pereira, PhD (Senior Field Application Scientist, Diagnostech, South Africa)Roberto completed his PhD in Molecular Medicine at the University of the Witwatersrand’s HIV Pathogenesis Research Unit in South Africa, where his research focused on HIV–immune system interactions and HIV vaccine development. His PhD work involved the expression, characterisation and immunogenicity testing of an HIV vaccine immunogen in a non-human primate model. He joined Diagnostech as a Field Application Scientist in 2021, supporting their Pathology portfolio for several years before moving over to the Molecular team to support their NGS customer base. In this role, he continues to grow his expertise in molecular technologies, with a particular focus on next-generation sequencing workflows and applications.Presenter:&nbsp;Jasmina Rajc, MD,PhD (Department Head, Pathology and Forensic medicine, University Hospital Osijek, Croatia)Jasminais a specialist in pathological anatomy with extensive clinical and academic experience. She is currently the Head of the Department of Pathology and Forensic Medicine at University Hospital Osijek and an Assistant Professor at the Faculty of Medicine, Josip Juraj Strossmayer University of Osijek in Croatia. Her professional interests include oncopathology, molecular diagnostics, and the evolving role of pathologists in comprehensive genomic profiling. She is actively involved in clinical and scientific research, including national and international studies.</blockquote>

Agilent Technologies: Improve Your NGS Workflow With The Magnis

Improve Your NGS Workflow With The Magnis

In the webinar we will share real-life experience using the Agilent Magnis system for automated NGS library preparation in a clinical diagnostics laboratory.

Mohlo by Vás zajímat

ISC 2026 – Krátký kurz 6: Statistická analýza a vizualizace kvantitativních LC/MS dat v softwaru R

Webináře LabRulezLCMS týden 11/2026

Naší ambicí není objevit lék na rakovinu, ale otevírat nové cesty výzkumu