<p><strong>Zkouší krotit bakterie a touží objevit struktury neznámých proteinů.</strong></p><p>„Věda je dobrodružství,“ říká <a target="_blank" rel="noopener noreferrer" href="https://www.uochb.cz/cs/adresar/208/jana-skerlova">Jana Škerlová</a> ze skupiny <a target="_blank" rel="noopener noreferrer" href="https://rezacova.group.uochb.cz/cs">Strukturní biologie</a> Pavlíny Maloy Řezáčové z ÚOCHB.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/UOCHB_Tomas_Bellon_Podcast_CH_Emic_56_Nove_technologie_pomahaji_vede_objevovat_nezname_svety_dbd6729ea2.jpg" alt="ÚOCHB/Tomáš Belloň – Podcast CHEmic #56 – Nové technologie pomáhají vědě objevovat neznámé světy." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_UOCHB_Tomas_Bellon_Podcast_CH_Emic_56_Nove_technologie_pomahaji_vede_objevovat_nezname_svety_dbd6729ea2.jpg 208w," sizes="100vw" width="1500" height="1125"></p><blockquote><p><strong>Podcast CHEmic</strong> představuje vědce a vědkyně z Ústavu organické chemie a biochemie AV ČR, jejich život v labech i mimo ně.</p></blockquote><blockquote><p>CHEmic najdete v podcastových aplikacích:</p></blockquote><blockquote><ul><li><a target="_blank" rel="noopener noreferrer" href="https://open.spotify.com/show/0ELIQTRkC3TFrVYnZgztsy?si=b4407e1f54824315&amp;nd=1"><strong>Spotify</strong></a></li><li><a target="_blank" rel="noopener noreferrer" href="https://podcasts.apple.com/cz/podcast/podcast-chemic-1-riskovat-se-vyplat%C3%AD-ne%C3%BAsp%C4%9Bchu-se-nesm%C3%ADme/id1683797089?i=1000611870620"><strong>Apple Podcasts</strong></a></li><li><a target="_blank" rel="noopener noreferrer" href="https://podcasts.google.com/feed/aHR0cHM6Ly9hbmNob3IuZm0vcy9kZmFhNjA4OC9wb2RjYXN0L3Jzcw"><strong>Podcasty Google</strong></a></li></ul></blockquote><blockquote><p>a na našem <a target="_blank" rel="noopener noreferrer" href="https://www.youtube.com/playlist?list=PLFJNDHHAxyMszoY-Hm4BGJ6nN7zNLZXO-"><strong>YouTube kanálu</strong></a>.</p></blockquote>

Podcast CHEmic #56 – Nové technologie pomáhají vědě objevovat neznámé světy

<p><strong>Lehké, flexibilní a účinné – takové mají být nové materiály pro elektromagnetické stínění, na kterých pracuje doktorka Filipa Oliveira v projektu podpořeném GAČR. Zaměřuje se na 2D materiály zvané MXeny, které by mohly nahradit tradiční kovy v ochraně elektroniky před rušivým zářením.</strong></p><h4><strong>Jak byste svůj projekt popsala laikovi a proč je důležitý?</strong></h4><p>Představte si vědce jako kuchaře, který vymýšlí nové recepty na materiály s přesně definovanými vlastnostmi. V našem případě se snažíme vytvořit materiály, které zamezí nežádoucímu elektromagnetickému rušení (EMI) z elektronických zařízení. Tyto materiály fungují jako štíty, obvykle se používají kovy jako železo nebo měď. My ale chceme, aby tyto štíty byly lehčí, pružnější, odolnější proti korozi a zároveň co nejméně odrážely EM vlny – protože jejich silný odraz může rušení ještě zhoršit. Tímto „vařením“ (tedy syntézou) materiálů s požadovanými vlastnostmi vytváříme MXeny – 2D materiály s obrovským potenciálem. Ty pak začleňujeme do polymerní matrice, čímž zvyšujeme jejich mechanickou odolnost a možnosti využití.</p><h4><strong>Co vás k výběru tohoto tématu inspirovalo?</strong></h4><p>Během doktorátu jsem se zabývala EMI stíněním pomocí polymerních kompozitů. Po příchodu do Česka mě nadchly možnosti 2D materiálů, zvlášť MXenů, které nabízejí obrovskou variabilitu. Tento projekt propojuje moje znalosti o EMI, syntéze MXenů a jejich aplikaci v polymerech. Chci vytvořit MXeny s požadovanými vlastnostmi, které se dají začlenit do polymerní matrice a stále účinně stíní – což je velká výzva.</p><h4><strong>Jaký je hlavní cíl vašeho výzkumu?</strong></h4><p>Cílem je syntéza chlor-terminovaných MXenů pomocí specifických Lewisových kyselin v taveninách a jejich následná integrace do lehkých, ohebných polymerních kompozitů pro účinné EMI stínění.</p><h4><strong>Co podle vás nejvíce zaujalo hodnoticí komisi?</strong></h4><p>Pravděpodobně náš návrh použít jako Lewisovy kyseliny trichloridy lanthanoidů (LnCl₃), které jsou běžně dostupné, ale zatím nebyly pro syntézu Cl-terminovaných MXenů použity. Je to jednoduchá a zároveň přístupná cesta ke kontrole povrchové chemie MXenů.</p><h4><strong>Povede projekt ke konkrétním aplikacím nebo technologiím?</strong></h4><p>Ano – například v elektronice, nositelné elektronice nebo jako ochranné vrstvy pro zdravotnické a automobilové zařízení. Potřeba efektivního EMI stínění poroste a náš výzkum může nabídnout řešení.</p><h4><strong>Čím je váš projekt výjimečný?</strong></h4><p>Použitím LnCl₃ jako Lewisovy kyseliny pro syntézu MXenů – je to dosud neprozkoumaný přístup.</p><h4><strong>S kým na projektu spolupracujete?</strong></h4><p>S kolegy ze skupiny profesora Sofera, kteří zajišťují morfologickou, strukturální a chemickou analýzu. Dále navazuji na spolupráci s RWTH Aachen v Německu a pro polymerní kompozity spolupracuji s doktorem Paulem Teixeirou z portugalského CENTI.</p><h4><strong>Jaké překážky očekáváte a jak se na ně připravujete?</strong></h4><p>Projekt je v počátku, takže očekávám problémy se syntézou a optimalizací. Také se učím, jak vést projekt jako hlavní řešitelka, včetně náboru a vedení studentů. Vše beru krok za krokem a s důrazem na týmovou práci.</p><h4><strong>Co vás na projektu nejvíce těší?</strong></h4><p>Možnost vytvořit něco, co má reálný dopad, a být součástí týmu talentovaných kolegů a studentů. Baví mě objevovat nové způsoby syntézy MXenů a jejich potenciální využití v praxi.</p><h4><strong>Co by mělo následovat po skončení projektu?</strong></h4><p>MXeny byly poprvé syntetizovány v roce 2011 a je zde stále co objevovat. Projekt může otevřít nové směry – například škálování výroby a nové aplikace v elektronice. Je to vzrušující oblast a věřím, že toho přijde ještě hodně.</p>

GAČR 2025: Filipa Oliveira zkoumá nové materiály pro elektromagnetické stínění

<p><strong>Dovolujeme si Vás srdečně pozvat na odborný webinář na téma:</strong></p><h4><strong>Charakterizace nanočástic průtokovou cytometrií nanoFCM</strong></h4><p>🗓️ <strong>Datum:</strong> 19. června 2025<br>🕙 <strong>Čas: </strong>10:00<br>⏱️<strong> Délka trvání:</strong> cca 60 minut<br>🔗 <strong>Odkaz pro registraci:</strong> <a target="_blank" rel="noopener noreferrer" href="https://docs.google.com/forms/d/e/1FAIpQLSfSxGpzV3iZLUYggotMj_m7ZCfW-nrcW9VIuQDCT2yzxg5IQw/viewform?usp=dialog"><strong>ZDE</strong></a></p><p>Webinář pořádá společnost <strong>ANAMET s.r.o.</strong> ve spolupráci se společností <strong>nanoFCM. Hostujícím řečníkem bude:</strong></p><ul><li>Freya Leech (NanoFCM, Velká Británie)</li></ul><h5><strong>Co se na webináři dozvíte:</strong></h5><ul><li>Představení přístroje <strong>NANOAnalyzer</strong> – unikátního průtokového cytometru navrženého pro analýzu nanočástic</li><li>Aplikační ukázky na <strong>extracelulárních vezikulách, virových částicích, lipozomech</strong></li><li>Prostor pro Vaše <strong>dotazy formou chatu</strong></li></ul><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Nano_FCM_NANOANALYZER_809953ffe2.jpg" alt="NanoFCM: NANOAnalyzer" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Nano_FCM_NANOANALYZER_809953ffe2.jpg 201w," sizes="100vw" width="871" height="674"></p><p><strong>V případě zájmu prosím neváhejte s registrací.</strong></p><p><strong>Těšíme se na setkání online!</strong></p><p>S přátelským pozdravem,</p><p>Mgr. Hynek Mácha, Ph.D. (ANAMET s.r.o.)</p><p><a href="macha@anamet.cz">macha@anamet.cz</a><br><a href="www.anamet.cz">www.anamet.cz</a></p>

Pozvánka na ANAMET webinář Charakterizace nanočástic průtokovou cytometrií nanoFCM

Webináře

Osobnosti

Popularizace

Věda a výzkum

Článek

Video

Nejbližší akce

Vysoká  škola chemicko-technologická v Praze spojuje tradici s nejmodernějšími nano- a biotechnologiemi a dalšími progresivními směry a obory ve vědě a výzkumu. Spolu s vynikajícím mezinárodním renomé a špičkovým přístrojovým vybavením otevírá každému studentovi možnosti zapojit se do vědeckých projektů dle vlastního výběru, umožňuje zahraniční stáže a je následně vstupenkou k prestižnímu, dobře ohodnocenému uplatnění doma i v zahraničí.

Vysoká škola chemicko-technologická v Praze

ÚOCHB AV ČR je přední mezinárodně uznávaná vědecká instituce, jejímž hlavním posláním je základní výzkum v oblasti chemické biologie a medicinální chemie, organické a materiálové chemie, chemie přírodních látek, biochemie a molekulární biologie, fyzikální chemie, teoretické chemie a analytické chemie.

Ústav organické chemie a biochemie AV ČR

Firma ANAMET s.r.o. nabízí přístrojové vybavení pro laboratoře, výzkumná pracoviště i pro měření v provozu. Na český a slovenský trh dodáváme špičkové přístroje zahraničních firem (zastupujeme více než 30 firem). Pro veškerou dodávanou techniku zajišťujeme řešení na míru, záruční a pozáruční servis včetně dodávek náhradních dílů a spotřebního materiálu.

ANAMET

Separation Science

Metrohm

Agilent Technologies

SIELC Technologies

Phenomenex

Waters Corporation

<div><div><p><strong>Let's go back to the Basics of Chromatography, Mass Spectrometry, Data Analysis and Trouble-shooting: understanding the importance of the basics will enable you to be more effective in your daily laboratory life.</strong></p><p>This journey started in 2024 and we are now pleased to invite you to join us to go deeper in fundamentals, troubleshooting and application specific topics.</p><h3><strong>EPISODE 5: MS Troubleshooting</strong></h3><p><strong>What will you learn?</strong></p><ul><li>Follow the Ion to understand important settings</li><li>DIY Maintenance</li><li>IN the Spotlight: Fluidics Systems and Ion Source option</li></ul><p><strong>What's next?</strong></p><ul><li>Check out the full Webinar Series Episodes List <a target="_blank" rel="noopener noreferrer" href="https://event.on24.com/eventRegistration/EventLobbyServlet?target=reg20.jsp&amp;eventid=4817889&amp;sessionid=1&amp;key=B9182AE813B3F8A30217606156F96B75&amp;groupId=5901784&amp;sourcepage=register"><strong>here</strong></a></li></ul><p><strong>Not sure to be able to attend live sessions?&nbsp;</strong></p><ul><li>Register today and watch the webinars on-demand</li></ul><blockquote><p><strong>Presenter: tba</strong></p></blockquote></div></div>

Waters Corporation: Back to Basics Advanced Webinar Series 2025

Back to Basics Advanced - Troubleshooting: MS

Follow the Ion to understand important settings. DIY Maintenance. IN the Spotlight: Fluidics Systems and Ion Source option.

<h4><strong>Expand Your Expertise with Our Chromatography Webinar Series 2025</strong></h4><p>A comprehensive journey through fundamental principles, HPLC optimization, and cutting-edge mixed-mode techniques. Led by industry experts, these free sessions provide practical insights and real-world applications to enhance your analytical skills.</p><h5><strong>Session 5: Real-World Applications &amp; Future Innovations in Mixed-Mode HPLC</strong></h5><ul><li>Advanced applications in pharmaceuticals, biotechnology, and food analysis</li><li>Strategies for handling complex sample matrices with mixed-mode chromatography</li><li>Emerging research and novel stationary phases</li><li>Future trends and developments in mixed-mode HPLC</li></ul><blockquote><p><strong>Presenter: </strong>Jovana Mitrovic (R&amp;D Chemist at SIELC Technologies)</p><p>Jovana holds a Master of Science in Molecular Engineering from the Pritzker School of Molecular Engineering at the University of Chicago and a Bachelor of Science in Biomedical Sciences from St. John’s University. Her background in molecular and biomedical sciences supports a multidisciplinary approach to addressing complex analytical challenges.</p></blockquote>

SIELC Technologies: HPLC Educational Webinar Series

Real-World Applications & Future Innovations in Mixed-Mode HPLC

Join us for a webinar discussing advanced applications in pharmaceuticals, biotechnology, and food analysis 

Applications & Future Innovations in Mixed-Mode HPLC

<div><p><strong>Light scattering techniques, are transforming the way we quantify and analyze nucleic acid (NA) and lipid nanoparticle (LNP) therapeutics, playing a critical role in development, RNA quality assessment, and quality control. This webinar will explore how combining multi-angle light scattering (MALS) with field-flow fractionation (FFF) or size-exclusion chromatography (SEC) provides high-resolution insights into critical attributes such as size distribution, NA integrity, overall stability, and payload encapsulation.&nbsp;</strong></p><p>Recent advances in SEC column technology has increased the quality and resolution of separations for complex mixtures of large NA constructs, as well as NA-protein complexes including Cas9 constructs. FFF-MALS allows for gentle, high-resolution separation, making it ideal for analyzing NA delivery systems like LNPs without compromising their integrity. Additionally, dynamic light scattering (DLS) and electrophoretic light scattering (ELS) enable rapid, automatable batch measurements, allowing for screening of factors such as size and surface charge.</p><p>Join us to discover the latest advancements in light scattering technology and learn how these powerful tools can accelerate pharmaceutical development and enhance your research.</p><h5><strong>Key Learning Objectives:</strong></h5><ul><li>Applications of SEC-MALS to in-depth NA distribution, conformation, and stability characterization</li><li>An introduction of DLS/ELS characterization for NA and LNP formulation screening</li><li>High resolution characterization of LNPs and NA delivery vehicles via FFF-MALS for size distribution, conformation, and payload</li></ul><blockquote><p><strong>Presenter:</strong> Parker Lee, Ph.D. (Waters | Wyatt Technology)</p><p>Dr. Parker Lee is a Field Applications Scientist at Waters | Wyatt Technology, serving customers in San Diego and the surrounding areas. Dr. Lee received his Ph.D. in Macromolecular Science &amp; Engineering, with a focus on developing new methods for drug delivery. He joined Wyatt Technology in 2022 after five years of work in macromolecule analytical development for various startups. As a Field Applications Scientist, he is responsible for working with customers to ensure they can utilize Wyatt’s light scattering instrumentation effectively to improve and accelerate their research.</p><p><strong>Presenter:</strong> Lavelay Kizekai, Ph.D. (Waters Corporation)</p><p>Lavelay Kizekai, BS, is a principal scientist at Waters Corporation. He joined Waters in 2009 and has since applied himself to developing new LC methods, leading column technology product development work, and establishing insight-based QC procedures for Waters products. His primary area of focus is biomolecule separations using size-exclusion chromatography (SEC). He was a core member of the team that recently brought to market a column suited to platform methods for monoclonal antibodies and antibody-drug conjugates. He is currently leveraging these SEC technologies and even newer breakthroughs for the characterization of gene-based therapeutics by multiangle light scattering.</p></blockquote></div>

Waters Corporation: Beyond Batch Methods: High Resolution Nucleic Acid and LNP Insights with Light Scattering Techniques

Beyond Batch Methods: High Resolution Nucleic Acid and LNP Insights with Light Scattering Techniques

Discover latest advancements in light scattering technology and learn how these tools can accelerate pharmaceutical development

High-Res Nucleic Acid & LNP Analysis via Light Scattering

<p><strong>It is critical to keep your lab current and one of the ways to achieve this is by leveraging new features and functionality. In this session, we will explore new and upcoming Empower Software features, including:</strong></p><ul><li>Updated functionality to simplify workflows requiring more stringent technical controls</li><li>New features to support expanded workflows</li><li>New data processing features and options</li></ul><p>Please join us for a lively discussion as we explore this topic. &nbsp;As always, please bring your questions for this exclusive opportunity to ask our experts anything about using Empower Software.</p><blockquote><p><strong>Presenter: </strong>Neil Lander (Principal Product Manager, Informatics, Waters Corporation)</p><p>Neil has worked for Waters Corporation since 1994 and has held a variety of positions including Technical Support Specialist, Technical Trainer, Manager Customer Education and currently, Principal Marketing Manager focusing on Informatics solutions. He provides internal support for Empower Chromatography Data System and is focused on developing laboratory software solutions that help organizations achieve their scientific and operational objectives. Prior to joining Waters, he was an analytical chemist where he gained experience in both the cosmetics and specialty chemical industries.</p><p><strong>Presenter: </strong>Dr. Andy Meyer (Senior Application Scientist, Wyatt Technology)</p><p>Dr. Andy Meyer joined Wyatt Technology in 2001, serving for several years as an Applications Scientist, then as Dean of Wyatt's "Light Scattering University" and as Director of Customer Service &amp; Support. After managing multiple regions in North America, Dr. Meyer is now a Senior Application Scientist for Wyatt. As a Wyatt customer, he completed his Ph.D. in Applied Science – Polymer Chemistry from the College of William and Mary in Virginia.</p></blockquote>

Waters Corporation: Empower Tips: Ask Me Anything About What's New in Empower Software

Empower Tips: Ask Me Anything About What's New in Empower Software

In this session, we will explore new and upcoming Empower Software features

Empower Tips What's New in Empower Software

<p>&nbsp;<strong>Key Learning Points</strong></p><ul><li>Learn best practices to optimize and utilize SLE for biological sample matrices</li><li>Review case studies to understand advantages of SLE and its limitations</li><li>Understand sustainable solvent use for SLE</li></ul><h4><strong>Who Should Attend</strong></h4><ul><li>Scientists and researchers pursuing research on low level analyte quantitation using LC-MS/MS.</li></ul><blockquote><p><strong>Speaker: </strong>Rajashree Chakravarti, Ph.D. (Global Product Manager, Phenomenex)</p><p>Rajashree Chakravarti, Ph.D., is a Global Product Manager at Phenomenex. With over a decade of experience in clinical diagnostics and research, she has a robust background in chromatography and mass spectrometry. Rajashree is a key contributor in innovation and new product development at Phenomenex, driving advancements in analytical techniques and solutions.</p></blockquote>

Phenomenex: Advancing Supported Liquid Extraction (SLE) with Strata SE – A Clean and Sustainable Solution

Advancing Supported Liquid Extraction (SLE) with Strata SE – A Clean and Sustainable Solution

Learn best practices to optimize and utilize SLE for biological sample matrices

Advancing Supported Liquid Extraction SLE with Strata SE

<p><strong>Veterinary drug residues are substances that can remain in animal products such as meat, dairy, eggs, and fish when these drugs are used to treat, prevent, or manage diseases in food-producing animals. These residues are of concern due to their potential to cause adverse effects on human health, including antimicrobial resistance (AMR), allergic reactions, and even carcinogenic or teratogenic outcomes. In light of these risks, countries and international regulatory bodies, such as the Codex Alimentarius and various governmental health agencies, have established maximum residue limits (MRLs) for specific drugs in food products. The control of these residues is critical not only for consumer safety but also for maintaining the integrity of food production systems globally.</strong></p><p>Join us for an in-depth webinar to gain insights into the latest regulatory requirements and analytical techniques for detecting veterinary drug residues in various food matrices. Learn how advanced technologies can enhance food safety and streamline testing processes.</p><h5><strong>By attending this presentation, you will learn about:</strong></h5><ul><li>Understanding regulations and MRL values for veterinary drugs</li><li>Innovative sample preparation methods to achieve low LOQs</li><li>Validation procedures, including single-laboratory validation (SLV) and multi-laboratory validation (MLV).</li><li>Utilizing the SCIEX 7500+ system for high-sensitivity quantitation and interference removal</li></ul><h5><strong>Who should attend:</strong></h5><ul><li>Food safety and quality control professionals</li><li>Analytical chemists and laboratory technicians</li><li>Regulatory affairs specialists in the food industry</li></ul><blockquote><p><strong>Presenter: </strong>Jianru Stahl-Zeng (Senior Technical Marketing Manager, SCIEX)</p></blockquote>

Separation Science: Advancing Food Safety and Regulatory Compliance: Comprehensive Screening of Veterinary Drug Residues in Food using SCIEX LC-MS/MS Technology

Advancing Food Safety and Regulatory Compliance: Comprehensive Screening of Veterinary Drug Residues in Food using SCIEX LC-MS/MS Technology

Gain insights into the latest regulatory requirements and analytical techniques for detecting veterinary drug residues in various food matrices.

Screening Vet Drug Residues in Food with SCIEX LC-MS/MS

<h5><strong>By attending this presentation, you will learn:</strong></h5><ul><li>Non-targeted analytical methodologies for PFAS characterizations</li><li>Practical examples of identifying emerging PFAS in industrial wastewater, indoor dust, and outdoor air</li><li>Evaluation of impact from ski waxes and potentially hydrophobic coatings</li><li>Environmental transport, transformation, and degradation of commercial PFAS materials</li></ul><h4><strong>Presentation 1: Non-targeted screening of per-/polyfluoroalkyl substances by cyclic ion mobility-mass spectrometry</strong></h4><ul><li>Karl J. Jobst, Associate Professor, Memorial University of Newfoundland and Labrador</li></ul><p>Concerns regarding the persistence, bioaccumulation behaviour, and toxicity of perfluorooctanoic acid (PFOA) and perfluorosulfonic acid (PFSA) have resulted in the creation of thousands of replacements whose occurrence, environmental fate, and adverse health impacts are unknown. This has driven analytical chemists to develop non-targeted screening (NTS) methods to accelerate the identification of unknown PFAS. Unlike other halogens, such as chlorine or bromine, 19F exists as a single stable isotope; thus, PFAS are not characterized by diagnostic isotope patterns.</p><p>This presentation describes a novel strategy to identify unknown PFAS using gas or liquid chromatographic cyclic ion mobility mass spectrometry (LCxcIMS or GCxcIMS). Unknown PFAS are recognized by having a collision-cross section (CCS) that is less than the sum of 100 Å2 and one fifth of their mass. By filtering the detected unknowns by mass and CCS, novel PFAS were revealed in a variety of environmental media, including industrial wastewater, indoor dust, and outdoor air, and their identities were confirmed through tandem mass spectrometry experiments with (synthesized) standards.</p><h4><strong>Presentation 2: Explore a multidimensional, non-targeted analytical approach using advanced chromatography and mass spectrometry to improve PFAS identification</strong></h4><ul><li>Frank Dorman, Senior Business Development Manager, Waters</li></ul><p>Poly/per-fluorinated aliphatic substances (PFAS) are of increasing concern in both the environment and food, and the understanding of their chemical complexity is strategically important. According to published literature, known PFAS chemicals, quantified on a targeted basis using available reference standards, have been shown to account for only 20-30% of total organic fluorine in “traditional source” samples. The remaining 70-80% is derived from other PFAS that are either commercial chemicals for which no reference standards are available, or downstream degradation/metabolism products of commercial chemicals with novel structures. Additionally, it is arguable if the target compound lists associated with regulatory methods even apply to “non-traditional” PFAS sources (non-AFFF, etc.).</p><p>This presentation will describe an analytical approach capable of utilizing both liquid- and gas-chromatographic separations coupled to a high-resolution ion-mobility spectrometer in series with a high-resolution time-of-flight mass spectrometer. This multidimensional, non-targeted separation dramatically improves identification of PFAS compounds. In addition, a post-acquisition data reduction strategy will be discussed, which effectively enables more automated characterization of non-targeted PFAS, either as native or degradation compounds. This becomes especially beneficial in “non-traditional” source contamination or where degradation products are of interest. This methodology will be utilized for a series of environmental forensic applications towards winter sports activities, an emerging area of concern with respect to PFAS contamination in the environment.</p><h5><strong>Who should attend:</strong></h5><ul><li>Environmental scientists and chemists</li><li>Analytical chemists</li><li>Laboratory directors and technical leads</li><li>Contract testing organizations (CTOs)</li><li>Government and academic lab researchers</li><li>Regulatory and risk assessment professionals</li><li>Environmental forensics researchers</li><li>Food safety scientists</li><li>Toxicologists and exposure scientists</li><li>Winter sports organizations and sustainability officers</li></ul><blockquote><p><strong>Presenter: </strong>Karl J. Jobst (Associate Professor, Department of Chemistry, Memorial University of Newfoundland and Labrador)</p><p>Karl J. Jobst is an Associate Professor in the Department of Chemistry at Memorial University of Newfoundland and Labrador. He obtained his Ph.D. in gas-phase ion chemistry from McMaster University under the supervision of Professor Johan K. Terlouw. His interests in the chemistry of interstellar clouds soon evolved into more earth-oriented research as a Visiting Fellow at Environment Canada, a Scientist with the Ontario Ministry of the Environment, as well as Adjunct Assistant Professor in the Department of Chemistry of his alma mater and in the Department of Physical and Environmental Sciences at the University of Toronto Scarborough. His current research focuses on the identification of emerging contaminants and understanding their environmental and human health impacts using novel mass spectrometry and computational methods. Dr. Jobst has (co)authored over 100 publications in peer-reviewed journals, and serves on the editorial board of Current Opinion in Environmental Science &amp; Health.</p><p><strong>Presenter: </strong>Frank Dorman &nbsp;(Senior Business Development Manager, Waters)</p><p>Frank Dorman is currently Senior Business Development Manager for Waters focusing on their global environmental business and, concurrently, a resident scholar in the Chemistry Department at Dartmouth College in Hanover, NH where he is active in teaching analytical chemistry to undergraduates and graduate students. In his role at Waters, Frank manages the research-focused environmental market, external collaborations, and interfaces with R&amp;D for new product development. Prior to this, Frank was an Associate Professor in the Department of Biochemistry and Molecular Biology (BMB) at Penn State University in University Park, PA. At Penn State, Frank served as a member of the Graduate Faculty in Biochemistry, Microbiology and Molecular Biology (BMMB), Chemistry (CHEM), Biogeochemistry (BGC) and the Forensic Science Program (FRNSC) and the Center for Molecular Toxicology and Carcinogenesis. Frank's scientific interests are in gas and liquid chromatography and fundamental characterization, instrumentation and column development, as well as mass spectrometry and atomic spectroscopy as applied to trace analysis in complex sample matrices.</p></blockquote>

SeparationScience: Emerging Strategies in PFAS Identification: Advanced Analytical Approaches for Environmental Samples

Emerging Strategies in PFAS Identification: Advanced Analytical Approaches for Environmental Samples

Explore how advanced non-targeted workflows using ion mobility and HRMS reveal hidden PFAS in environmental samples

PFAS Identification: Advanced Strategies for Environment

<p><strong>A 3-part webinar series to help you stay ahead in nitrosamines &amp; NDSRI analysis, from regulatory clarity to method mastery and compliance confidence.</strong></p><h4><strong>Session 1: Nitrosamines Landscape in Tandem with Analytical Technologies: Is Your Lab Nitrosamine Ready?</strong></h4><p><strong>Nitrosamines and NDSRIs continue to challenge the pharmaceutical industry with evolving regulations and analytical complexities. This session focuses on understanding the distinctions between nitrosamines and NDSRI's and aligning your lab with the latest regulatory expectations and technology advancements.</strong></p><p>Get expert insights into risk assessment, mitigation strategies, and the analytical technologies critical to staying compliant and efficient. The session will feature an exclusive panel discussion with Dr. Saji Thomas, Associate Vice President, Analytical Research &amp; Development, Sun Pharma, who will share practical, real-world insights from the frontlines of nitrosamine testing and regulatory preparedness.</p><h5><strong>Key Takeaways:</strong></h5><ul><li>Understanding the difference between Nitrosamines and NDSRI's</li><li>Regulatory scenarios: API, Formulations, and NDSRI's</li><li>Key updates in global guidance and risk assessment</li><li>Mitigation strategies for NDSRI's</li><li>Industry discussion: evolving testing landscape, workflow challenges, and future directions</li><li>Live Q&amp;A with Agilent and industry experts</li></ul><blockquote><p><strong>Presenter:</strong> Dr. Saji Thomas (Associate Vice President, Analytical Development, Sun Pharmaceutical Industries Limited)</p><p>Dr. Saji Thomas earned his Ph.D. in chemistry from Kumaun University, Nainital, Uttarakhand. With 32 years of diverse experience in the pharmaceutical industry, he has developed cost-competitive, IP, EHS, and regulatory-compliant technologies for generic APIs, intermediates, radiopharmaceuticals, onco APIs, life science ingredients, animal nutrition products, fine chemicals, CRAMS/CDMO, and drug discovery functions.</p><p>He is skilled in chemical analysis, chromatography, solid-state characterization, spectroscopy, impurity profiling, impurity isolation, and structural elucidation using techniques such as LC-MS/MS, HRMS, IR, NMR, and EA. Also excels in developing and validating highly sensitive MS methods for nitrosamines, NDSRIs, and GTIs.</p><p>He has extensive experience in pharmaceutical quality management systems (QMS), creating state-of-the-art manufacturing and QA systems, conducting OOT and OOS investigations, identifying root causes, implementing CAPA, and engaging in FDA remediation activities. He is a co-inventor of 25 process patents and has published 14 research papers in international journals.</p><p>Currently, Dr. Thomas serves as the Associate Vice President of Analytical Development at Sun Pharmaceutical Industries Limited in Gurugram. His previous roles include positions at Jubilant Pharmova Limited, Indoco Remedies, Jubilant Life Sciences Limited, Solaris Chemtech, and Alta Laboratories Limited.</p><p><strong>Presenter:</strong> Dr. Kuldeep Sharma (Sales Development Manager - Pharma, Agilent Technologies)</p><p>Kuldeep Sharma has over 19 years of experience in the areas of bioanalytical research, drug metabolism &amp; pharmacokinetics, and pharma regulatory compliance. He has accomplished a PhD in biotechnology. His professional journey covers over 12 years in analytical research (associated with R&amp;D at Zydus Cadila, Lambda, Pliva, and Jubilant Biosys) and the last 7 years in analytical instrument sales, marketing, and business development. With over 21 research articles published in international journals, he presents the convention of continuous learning.</p></blockquote>

Agilent Technologies: Nitrosamines Navigator: Be Confident with Agilent Workflows

Nitrosamines Landscape in Tandem with Analytical Technologies: Is Your Lab Nitrosamine Ready?

Is your lab nitrosamine-ready? Join Session 1 to explore regulatory trends, risk strategies, and tech updates with expert insights from Sun Pharma and Agilent.

Is Your Lab Nitrosamine Ready?

<div id="contentLeft"><div id="realLeftContent"><div id="summary2" dir="ltr" aria-live="off"><div><div dir="" aria-atomic="true"><p><strong>Ion chromatography (IC) has long been a trusted technique for ionic analysis, with conductivity detection as its standard workhorse. However, alternate detection technologies are unlocking new possibilities for sensitivity, selectivity, and broader application coverage. In this webinar, we’ll explore three powerful alternatives: UV/Vis, amperometric, and mass spectrometry (MS) detection, and examine how each can enhance your IC workflows.</strong></p><p>We’ll discuss practical examples of when to apply each detection method, helping you understand which technologies are best suited for different analytes, sample types, and industry needs. Whether you're analyzing food and beverage products, monitoring environmental contaminants, or working with other complex matrices, alternate detectors can offer significant advantages. Along the way, we’ll share key insights on optimizing your methods for each detector type—covering considerations like system setup, sample prep, and choosing the right chemistry. Whether you're expanding into new applications or looking to refine existing methods, this session will offer actionable guidance to help you get the most out of your IC system.</p><h4><strong>Who should attend?</strong></h4><ul><li>Analytical chemists and method development scientists looking to expand or refine their use of ion chromatography</li><li>Lab managers and technical staff seeking to evaluate or implement alternate detection technologies</li><li>Professionals in environmental, food, pharmaceutical, or industrial sectors aiming to enhance analytical capabilities</li></ul><h4><strong>Key learning points</strong></h4><ul><li>Learn the core principles and application benefits of UV/Vis, amperometric, and mass spectrometry (MS) detection in ion chromatography</li><li>Understand how to choose the right detection method based on sample type, analyte characteristics, and application requirements</li><li>Explore practical method development tips to optimize performance with each detection technology</li></ul><blockquote><p><strong>Presenter: </strong>Jay Gandhi. PhD (Vertical Market Manager, Metrohm USA)</p><p>Dr. Gandhi brings 38+ years of proficiency with virtually all analytical instrumentation and the techniques of Environmental, Petrochemical and Pharmaceutical testing and research. Jay is currently involved with the development of «Total Fluorine» analysis using combustion ion chromatography (CIC). Since 2003, Dr. Gandhi is a non-paid adjunct faculty at University of Houston-Clearlake where he enjoys guiding graduate and post-graduate students in their independent study program.</p><p><strong>Presenter: </strong>Bikash Chouhan, PhD (Applications Specialist, Ion Chromatography, Metrohm USA)</p><p>Bikash Chouhan is an Applications Specialist for Ion Chromatography at Metrohm USA. He completed his PhD in Analytical Chemistry from the University of Texas at Arlington (UTA). His area of research during his PhD was in Capillary Scale Ion Chromatography. He has worked as a Post Doc at Department of Chemistry and Biochemistry, UTA and as a Senior Scientist in IC at Eurofins, before joining Metrohm USA. He is currently involved in expanding IC applications to more unique and challenging sample matrices.</p></blockquote></div></div></div></div></div>

Metrohm: Expanding Ion Chromatography with Advanced Detection Technologies

Expanding Ion Chromatography with Advanced Detection Technologies

Boost your IC performance with UV/Vis, amperometric, and MS detection. Learn when and how to apply alternate detectors for better sensitivity and selectivity.

Expanding IC with Advanced Detection Technologies

<p>Webinář pořádá společnost <strong>ANAMET s.r.o.</strong> ve spolupráci se společností <strong>nanoFCM. Hostujícím řečníkem bude:</strong></p><ul><li>Freya Leech (nanoFCM, Velká Británie)</li></ul><h5><strong>Co se na webináři dozvíte:</strong></h5><ul><li>Představení přístroje <strong>NANOAnalyzer</strong> – unikátního průtokového cytometru navrženého pro analýzu nanočástic</li><li>Aplikační ukázky na <strong>extracelulárních vezikulách, virových částicích, lipozomech</strong></li><li>Prostor pro Vaše <strong>dotazy formou chatu</strong></li></ul><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Nano_FCM_NANOANALYZER_809953ffe2.jpg" alt="NanoFCM: NANOANALYZER" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Nano_FCM_NANOANALYZER_809953ffe2.jpg 201w," sizes="100vw" width="871" height="674"></p><p><strong>V případě zájmu prosím neváhejte s registrací.</strong></p><p><strong>Těšíme se na setkání online!</strong></p><p>S přátelským pozdravem,<br>Mgr. Hynek Mácha, Ph.D. (ANAMET s.r.o.)</p>

LabRulez / AI: Charakterizace nanočástic průtokovou cytometrií nanoFCM

Charakterizace nanočástic průtokovou cytometrií nanoFCM

Webinář: NANOAnalyzer – průtoková cytometrie pro analýzu nanočástic. Ukázky na EV, virech, lipozomech. Prostor pro dotazy. Registrujte se!

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