Plnění požadavků směrnice EU o pitné vodě: klíčová role přípravy vzorků při analýze stopových kontaminantů

Vážení zákazníci a obchodní partneři,rádi bychom vás informovali, že dnešním dnem 12. ledna 2026 nabývá účinnost část Vyhlášky 252/2004 Sb., o hygienických požadavcích na pitnou a teplou vodu a četnost a rozsah kontroly pitné vody, ve znění pozdějších předpisů.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Lab_Rulez_AI_Rozbory_pitna_voda_ALS_CR_1_b7a65fb299/LabRulez-AI-Rozbory-pitna-voda-(ALS-CR)-1.jpg" alt="LabRulez/AI: Rozbory pitná voda (ALS Čr) " srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Lab_Rulez_AI_Rozbory_pitna_voda_ALS_CR_1_b7a65fb299/thumbnail_LabRulez-AI-Rozbory-pitna-voda-(ALS-CR)-1.jpg 156w," sizes="100vw" width="815" height="815"><h4>Co se mění?</h4>12. ledna 2026 vstoupila v platnost novela Vyhlášky č. 252/2004 Sb., která rozšiřuje seznam chemických ukazatelů v příloze č.1, tabulky B o tyto ukazatele:<ul><li>Řádek 20 - Bisphenol A (BPA): Limitní hodnota 2,5 µg/l</li><li>Řádek 29 - Halogenoctové kyseliny (HAA): Limitní hodnota 60 µg/l (limitní hodnota se vztahuje na součet kvantitativně zjištěných koncentrací kyselin: chloroctová, dichloroctová, trichloroctová, bromoctová a dibromoctová)</li><li>Řádek 52 - Suma PFAS: Limitní hodnota: 0,10 µg/l (suma PFAS zahrnuje: PFBA, PFPA, PFHxA, PFHpA, PFOA, PFNA, PFDA, PFUnDA, PFDoDA, PFTrDA, PFBS, PFPS, PFHxS, PFHpS, PFOS, PFNS, PFDS, perfluoroundekansulfonová kyselina, perfluorododekansulfonová kyselina, perfluorotridekansulfonová kyselina)</li></ul><blockquote>Podrobné znění vyhlášky naleznete <a target="_blank" rel="noopener noreferrer" href="https://www.zakonyprolidi.cz/cs/2004-252/zneni-20260112">zde</a>.</blockquote><ul><li>Od dnešního dne tedy musí být tyto parametry zahrnuty do pravidelných kontrol pitné vody.</li><li>Laboratoře ALS Czech Republic již nabízí <a target="_blank" rel="noopener noreferrer" href="https://lcms.cz/products/991">rozbory pitných vod v plném rozsahu dle této vyhlášky</a>.</li></ul>Kontaktujte nás!Máte dotazy ohledně nových parametrů a požadavků? Potřebujete poradit s implementací?<blockquote>Jsme tu pro vás! Neváhejte nás kontaktovat na e-mailu: info.cz@alsglobal.com nebo na tel.: +420 226 226 228</blockquote>

Nové limity pro testování pitné vody

Ačkoliv moderní zemědělství potřebuje vycházet z přesných dat o půdních, rostlinných i environmentálních podmínkách v reálném čase, cenově dostupná, dostatečně citlivá a zároveň robustní monitorovací zařízení pro tento účel v současné době chybí. Jako vhodné řešení se podle vědců nabízí nízkonákladové senzory založené na nových chytrých materiálech a technologiích tisku. Dosavadní výsledky multiioborového výzkumu i návrhy na vývoj těchto zařízení představili výzkumníci z Česka, Velké Británie, Španělska i USA v přehledovém článku v prestižním časopise <a target="_blank" rel="noopener noreferrer" href="https://www.nature.com/articles/s41467-026-68778-6#Abs1">Nature Communications</a>.„Senzorické technologie pro monitorování zdraví rostlin jsou stále v plenkách. Na trhu jsou běžné dostupné jen jednoduché senzory, které jsou schopné monitorovat pouze základní parametry jako například pH, vlhkost v půdě, případně teplotu. Pokud však mají zemědělci čelit současným výzvám včetně klimatických změn a zajistit pro lidstvo dostatek potravy, potřebují mnohem účinnější pomocníky, jež jim umožní monitorovat například i různé patogeny včetně bakterií či plísní. Podle nás je vhodným řešením kombinace nových chytrých materiálů a tisku pro produkci levných, odolných a škálovatelných materiálů,“ uvedl první autor článku David Panáček z CATRIN, který na studii pracoval během své stáže v Imperial College London.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/CATRIN_Soucasne_senzory_nestaci_Vedci_navrhuji_novou_cestu_ke_sledovani_zdravi_rostlin_b4014952a3.jpg" alt="CATRIN: David Panáček" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_CATRIN_Soucasne_senzory_nestaci_Vedci_navrhuji_novou_cestu_ke_sledovani_zdravi_rostlin_b4014952a3.jpg 208w," sizes="100vw" width="1536" height="1152">Senzory pro monitorování zdraví rostlin například v porovnání s podobnými zařízeními pro humánní medicínu pokulhávají. Klíčovou roli v možném posunu hraje podle autorů pokrok v materiálových vědách, jenž vývoj škálovatelných senzorových technologií umožní. „Tiskové techniky včetně inkoustového tisku, sítotisku, aerosolového tisku, 3D tisku a přímého laserového zápisu nabízejí flexibilní cesty k výrobě ohebných senzorů, senzorů pro velké plochy i senzorů integrovaných přímo do rostlin. Přehledový článek shrnuje nedávný pokrok v oblasti tisknutelných nízkorozměrných materiálů pro zemědělské senzory, analyzuje jejich fyzikálně-chemické vlastnosti ve vztahu k senzorovému výkonu a diskutuje hlavní výzvy a budoucí příležitosti vyžadující mezioborovou integraci,“ uvedl jeden z korespondujících autorů Michal Otyepka.Výzkum propojil materiálové vědce, chemiky, biology, odborníky na senzing i technologie tisku. Materiálový výzkum a využití chytrých materiálů na bázi grafenu zaštítili vědci CATRIN Univerzity Palackého a VŠB-Technické univerzity Ostrava, znalostmi o vývoji rostlin, jejich reakcích na stresové podmínky i monitorování jejich vlastností přispěli rostlinní biologové z CATRIN, o oblast elektroniky se postarali výzkumníci z Imperial College London, technologiím tisku se věnovali zástupci <a target="_blank" rel="noopener noreferrer" href="https://lcms.cz/companies/36">CEITEC – VUT</a>. V týmu nechyběli ani přední odborníci na senzing z Katalánského institutu nanověd a nanotechnologií v Barceloně a svými bohatými znalostmi přispěl i „otec senzingu a elektrochemie“ Joseph Wang z University of California San Diego.„Jedná se o průlomovou studii na toto téma, k níž se podařilo přizvat skutečně velká jména v daných oborech. V neposlední řadě studie dokládá to, že interdisciplinarita v CATRIN dává vzniknout zcela novým a perspektivním výzkumným tématům, jako je rostlinný senzing a jeho využití pro studium interakce rostlin s prostředím a chytrém zemědělství,“ doplnila další z korespondenčních autorů Nuria De Diego. &nbsp;

Současné senzory nestačí. Vědci navrhují novou cestu ke sledování zdraví rostlin

Životní prostředí

Vody

Vědecký článek

Věda a výzkum

Video

Článek

Laboratoře

Základním posláním společnosti ALS je pomáhat našim klientům se kvalifikovaně a informovaně rozhodovat tím, že poskytuje spolehlivá, konzistentní a reprodukovatelná laboratorní data. Zaručujeme spolehlivé výsledky, krátké dodací lhůty, nepřetržitý provoz, odbornou podporu a odběry vzorků.

ALS Czech Republic

Český institut výzkumu a pokročilých technologií (Czech Advanced Technology and Research Institute – CATRIN) je vysokoškolský ústav Univerzity Palackého v Olomouci. Vznikl integrací vědeckých týmů Centra regionu Haná pro biotechnologický a zemědělský výzkum (CRH), Regionálního centra pokročilých technologií a materiálů (RCPTM) a Ústavu molekulární a translační medicíny (ÚMTM) s cílem úzce propojit vědecké kapacity v oblasti biomedicíny, nanotechnologií, nových materiálů, výzkumu rostlin či biotechnologií a ještě úspěšněji čelit  globálním výzvám současného světa, k nimž patří například dopady klimatických změn, boj s novými typy patogenů, diagnostika a léčba civilizačních onemocnění, odvrácení hrozící potravinové krize, získávání a ukládání „zelené“ energie, zajištění dostatku pitné vody, ochrana životního prostředí a řada dalších.

CATRIN

Společnost Organomation, založená v roce 1959, navrhuje a vyrábí vysoce kvalitní dusíkové koncentrátory a extrakční systémy. Jejich laboratorní přístroje, známé svou inovativností a odolností, se používají po celém světě pro efektivní přípravu vzorků a jsou doprovázeny silnou zákaznickou podporou.

Organomation

Agilent Technologies

Technology Networks

Thermo Fisher Scientific

Shimadzu Corporation

Waters Corporation

Join us for the fourth SELECT SERIES MRT in Action deminar. In this installment of our series, we will show new levels of imaging clarity and confidence being obtained with MRT, at speeds that realize useful improvements in throughput.
In our applications demo lab we will show the simplicity of changing between MALDI and DESI XS modes, both available on the MRT instrument. We will also highlight new imaging workflows, enabled by micro apps, developed to extract meaningful information quickly.
The session will conclude with a live Q&amp;A where Emmanuelle Claude, Wei Rao and other members of the team, who will be on hand to answer all of your questions. 
Why Should You Attend?
<ul>
<li>Discover how the characteristics of the MRT aid mass spectrometry imaging workflows</li>
<li>Learn how the different imaging modes work to extend imaging coverage</li>
<li>Understand how MRT imaging data is processed through various workflows</li>
</ul>
<blockquote>
Presenter: Emmanuelle Claude (Consulting Scientist, Waters Corporation)
</blockquote>
<blockquote>
Emmanuelle Claude started at Waters Corporation in October 2000 as an Applications Chemist in the Proteomics and Genomics Marketing group, developing automated Peptide Mass Fingerprint (PMF) MS methods using a MALDI-TOF mass spectrometer. Over the years she developed several methods in the proteomics analytical space using MALDI TOF and naturally moved in starting the development of Mass Spectrometry Imaging (MSI) at Waters corporation over 15 years ago.
</blockquote>
<blockquote>
She has been involved with hardware and software R&amp;D to ensure that the solutions are fit-for-purpose for the MSI community and beyond. She has worked extensively with the main MSI leaders in Europe and the US such as Prof Heeren in the Netherlands, Prof Clench, Prof Takats and Bunch in the UK and Prof Caprioli in the US. She has been a Principal Scientist since 2014 and became a Consulting scientist in 2021. Emmanuelle is managing the MS imaging application team at Waters, who are involved in developing new applications and methods for imaging by both MALDI and DESI mass spectrometry.
</blockquote>
<blockquote>
Presenter: Wei Rao (Principal Applications Chemist, Waters Corporation)
</blockquote>
<blockquote>
Wei Rao is currently working as a Principal Applications Chemist in the European Applications Laboratory at Waters Wilmslow, focusing on MS imaging and ambient MS with the DESI XS platform. He has more than 12 years of ambient MS imaging experience, and has worked in various posts in the UK, US, China, and many countries within the APAC region, bringing with him a unique global perspective to the field.
</blockquote>

Accelerated Imaging Clarity

In our applications demo lab we will show the simplicity of changing between MALDI and DESI XS modes, both available on the MRT instrument.

In this virtual Ask Me Anything session we are offering you a chance to delve into the fascinating world of PFAS (Per- and Polyfluoroalkyl Substances).
We are honored to present Dr. Carol Kwiatkowski, a distinguished science and policy senior associate from Green Science Policy, as our esteemed guest.
Dr. Kwiatkowski will be your guide, providing expert insights and answering all your questions about PFAS. From its profound health and environmental concerns to the ever-evolving landscape of regulations, restrictions, and detection techniques. No question is off limits! 
During this session, you can expect to:
<ul>
<li>Engage in a Live Q&amp;A: Seize the opportunity to directly interact with Dr. Kwiatkowski, posing your most thought-provoking questions, and receive real-time, well-informed answers.
</li>
<li>Gain Expert Perspectives: Immerse yourself in a vibrant exchange of ideas, as Dr. Kwiatkowski shares her profound insights on questions posed by fellow participants.
</li>
</ul>
<blockquote>
Presenter: Dr. Carol Kwiatkowski (Adjunct Assistant Professor, North Carolina State University)
</blockquote>

Technology Networks: Ask Me Anything: PFAS

Ask Me Anything: PFAS

Delve into the fascinating world of PFAS.

Learn how to improve assay robustness and reduce the burden associated with migrating methods downstream in the analysis and monitoring of product quality attributes of biopharmaceuticals.
<blockquote>
Presenter: Pawel Bigos (Scientist, Waters Corporation)
</blockquote>
<blockquote>
Pawel is a Scientist at Waters Corporation in the QA/QC Biologics group. He joined Waters in 2022 and has primarily focused on biomolecule separations using Ion-Exchange (IEX) and Size Exclusion (SEC) Chromatography. Prior to Waters, he held positions at Frequency Therapeutics, Novartis, and Symbiotic Research. Pawel received his BS degree in chemistry from the University of South Florida.
</blockquote>

Waters Corporation: Advancing Technology for Better Medicine

Advancing Technology for Better Medicine

Learn how to improve assay robustness and reduce the burden associated with migrating methods downstream.

Ion Mobility (IM) advancements in Software, Data Bases, AI and Machine learning are quickly improving capabilities to make unknown identifications, separate and ID isomers, as well as improve workflows associated with metabolomics, lipidomics, PFAS, and qual-quant screening.
In addition, IM measurements are significantly improved with HRdm High Resolution Demultiplexing. This is the first commercial IM instrument to enable the simultaneous combination of high drift resolution, while at the same time achieving all four of the following measurement capabilities: broad mass range in a single injection, multiplexing to increase sensitivity, compatibility with fast chromatographic acquisition rates , and highest precision in CCS measurements. For more accurate CCS predictions, the better precision in the CCS training set improves AI machine learning SW. This can significantly reduce the number of potential candidate structures to select from when making unknown identifications.
<blockquote>
Presenter: Carrie McDonough, PhD (Carnegie Mellon University)
</blockquote>

Agilent Technologies: Towards more Comprehensive Characterization of PFAS Exposure using Ion Mobility and High-Resolution Mass Spectrometry

Towards more Comprehensive Characterization of PFAS Exposure using Ion Mobility and High-Resolution Mass Spectrometry

Towards more Comprehensive Characterization of PFAS Exposure using Ion Mobility and High-Resolution Mass Spectrometry.

Characterization of PFAS Exposure using IM and HRMS

Ion Mobility (IM) advancements in Software, Data Bases, AI and Machine learning are quickly improving capabilities to make unknown identifications, separate and ID isomers, as well as improve workflows associated with metabolomics, lipidomics, PFAS, and qual-quant screening.
In addition, IM measurements are significantly improved with HRdm High Resolution Demultiplexing. This is the first commercial IM instrument to enable the simultaneous combination of high drift resolution, while at the same time achieving all four of the following measurement capabilities: broad mass range in a single injection, multiplexing to increase sensitivity, compatibility with fast chromatographic acquisition rates , and highest precision in CCS measurements. For more accurate CCS predictions, the better precision in the CCS training set improves AI machine learning SW. This can significantly reduce the number of potential candidate structures to select from when making unknown identifications.
<blockquote>
Presenter: Blaine Roberts, PhD (Associate Professor, Department of Biochemistry and Department of Neurology, Emory University)
</blockquote>
<blockquote>
Dr. Blaine Roberts is an Associate Professor In the Department of Biochemistry and Department of Neurology at Emory University. He obtained his Bachelor of Science in Chemistry at Montana State University and his PhD in Biochemistry and Biophysics from Oregon State University. His research group focuses on using protein biochemistry and mass spectrometry to understand Alzheimer’s, Parkinson’s and amyotrophic lateral sclerosis. He has interest in understanding the role of metals in biology and has developed new proteomic technologies to measure metalloproteins. Further, his group is using proteomics to characterize new blood borne biomarkers for Alzheimer’s and Parkinson’s disease.
</blockquote>

Agilent Technologies: The Hidden Pathophysiology of Lipids and Proteins in Alzheimer’s Revealed with Ion Mobility MS and Quantitative QQQ Biomarker Assays

The Hidden Pathophysiology of Lipids and Proteins in Alzheimer’s Revealed with Ion Mobility MS and Quantitative QQQ Biomarker Assays

The Hidden Pathophysiology of Lipids and Proteins in Alzheimer’s Revealed with Ion Mobility MS and Quantitative QQQ Biomarker Assays.

Pathophysiology of Lipids and Proteins in Alzheimer’s

Emerging therapies like Synthetic Peptides &amp; Oligonucleotides are catching the attention due to its capabilities to improve their physicochemical and biological properties, such as efficacy, stability, bioavailability, safety, etc.
These require thorough understanding &amp; analysis of these molecules and exclusive strategies to quantify these molecules in various biological matrices.
<blockquote>
Presenter: Dr. Ravi Shah (M.S.; PhD), (Head of the Department - Pharmaceutical Analysis, National Institute of Pharmaceutical Education and Research - Ahmedabad)
</blockquote>
<blockquote>
Dr. Ravi is Head of the Department of pharmaceutical analysis at NIPER- Ahmedabad. He has received his M.S. (Pharm) and PhD from NIPER, Mohali under the guidance of Prof. Saranjit Singh. Before joining back to academic research, he served at various levels in industry to understand the needs of pharma sector. He had started his career with Biocon-BMS research and development center, where he was responsible for analytical activities related to IND and NDA fillings of drug discovery leads. Post drug discovery understanding, he joined Dr. Reddy’s in 2015 as associate director and department head for Analytical R&amp;D Bangalore facility to learn generic drug development. He gathered vast experience on analytical method development, and regulatory requirements pertaining to DMF/ ANDA fillings at US and EU. He also worked significantly on complex generics for getting pharmaceutical equivalence through robust CQA, CPP and CMA correlations through QbD approaches.
</blockquote>
<blockquote>
He has published many research articles in almost every international analytical journal like Analytical Chemistry, Drug Testing and Analysis, Journal of Chromatogaphy A,Journal of Chromatogaphy B,Journal of Pharmaceutical and Biomedical Analysis, Trends in Analytical Chemistry, Analytical Methods, Analytical and Bioanalytical Chemistry, Rapid communications in mass spectrometry etc.
</blockquote>
<blockquote>
Presenter: Dr. Ashish Pargaonkar (Biopharma Workflow Commercialization Lead, Agilent Technologies)
</blockquote>
<blockquote>
Dr. Ashish Pargaonkar is a Lead for Biopharma Workflow Commercialization team for India and also Manager for Centre of Excellences at Bangalore. A Microbiologist by education with a Ph.D, he holds more than 20 years of experience for Biopharma market applications on Hi Resolution Mass Spectrometry. He has a long record of successful demonstrations and customer engagements on workflows for CQA’s, Intact mass, peptide mapping, HCP and Glycans using Agilent state-of-the art solutions. He has authored ASMS posters on media components and therapeutic peptides. Dr. Ashish has been invited speaker at several conferences and workshops at Biosimilar Congress, ADC 2018, IIT (Mumbai, Delhi), ICT (Mumbai), PSI events.
</blockquote>
<blockquote>
Presenter: Ms. Paramjeet Khandpur (Biopharma Workflow Commercialization Lead, Agilent Techologies)
</blockquote>
<blockquote>
Paramjeet Khandpur, M.Tech., holds a bachelor’s degree in chemical engineering from VTU University and a Master&#39;s in Bioprocess Technology from the Institute of Chemical Technology, Mumbai. Paramjeet is currently the Biopharma Workflow Commercialization Lead at Agilent. In this role, she leverages her expertise to deliver comprehensive workflow solutions and offer support to customers, catering to their analytical requirements across the Biopharma value chain.
</blockquote>
<blockquote>
Previously, she worked as an Application Engineer at Agilent&#39;s Centre of Excellence Lab in Bangalore, specializing in various liquid chromatography platforms. She also collaborated with users in the Pharma and Biopharma industry for method development, troubleshooting, and method transfer.
</blockquote>

Agilent Technologies: Get the Perfect Answer for Synthetic Peptides & Oligonucleotides

Get the Perfect Answer for Synthetic Peptides & Oligonucleotides

Emerging therapies like Synthetic Peptides & Oligonucleotides are catching the attention due to its capabilities to improve their properties.

Get the Perfect Answer for Synthetic Peptides

Introducing Shimadzu’s Multimodal Imaging System, designed to provide advanced clinical imaging and accelerate research breakthroughs. The powerful system consists of two instruments: the Laser-ablation ICP-MS, which acquires information on the element distribution, and the award-winning iMScope QT MALDI-MS Microscope, which provide information on the compound distribution. The data from both instruments can be seamlessly analyzed using the intuitive IMAGEREVEAL MS software without the need for special data conversion. This integrated data analysis unlocks unparalleled insights into the spatial distribution of elements and biomolecules within tissues and cells, thereby opening up new avenues for diagnostics, biomarker discovery, and drug development.
Join us at our Shimadzu Digital Classrooms as we delve into the world of Multimodal Imaging by exploring real-world application case studies. Experience firsthand how this cutting-edge technology, together with integrated data analysis, provides profound insights quickly and accurately to advance clinical research.
Don&#39;t miss this opportunity to discover the capabilities of Shimadzu&#39;s multimodal imaging system - Register now!
<h3>Learning Objectives:</h3>
<ul>
<li>Discover capabilities of Shimadzu&#39;s Multimodal Imaging System, integrating LA-ICPMS and MALDI-MS Microscopy</li>
<li>Gain comprehensive insights into Shimadzu&#39;s complete solution for LA-ICP-MS</li>
<li>Learn about Shimadzu iMScope QT, a Next-Generation Mass Spectrometry Imaging system</li>
<li>Explore real-world clinical application case studies leveraging the Multimodal Imaging approach</li>
</ul>
<blockquote>
Presenter: Pravin Konde, PhD (Senior Product Specialist, Shimadzu (Asia Pacific) Pte Ltd)
</blockquote>
<blockquote>
Pravin Konde is a Senior Product Specialist (for Spectroscopy &amp; TOC) at Shimadzu Asia Pacific Singapore. He has about 15 years of industry experience of which about 12 years in analytical instruments with expertise in trace element analysis and spectroscopy applications. He is engaged primarily in technical support to regional sales teams and customers. Prior to joining industry, he has done his PhD in Chemistry from Institute of Chemical Technology (formerly UDCT), Mumbai, India.
</blockquote>
<blockquote>
Presenter: Naatasha Isahak, PhD (Product Specialist (Life Sciences), Shimadzu (Asia Pacific) Pte Ltd)
</blockquote>
<blockquote>
Naatasha Isahak is a Product Specialist for MALDI and Life Sciences Products from Shimadzu Asia Pacific Pte Ltd. She has received her PhD from the University of Sydney (Chemistry) working on surface initiated polymerisation on silica nanoparticles using RAFT polymerisation and bioorthogonal conjugation of peptides using Native Chemical Ligation. She then spent 5 years working on developing platforms for stem cells and organoids characterization that included working with microfluidic devices and helical polymers. Naatasha joined Shimadzu in 2022 to expand her experiences to MALDI characterization on materials and biological samples.
</blockquote>

Shimadzu: Powerful Multimodal Clinical Imaging System with LA-ICP-MS and MALDI-MS Microscopy

Powerful Multimodal Clinical Imaging System with LA-ICP-MS and MALDI-MS Microscopy

LA-ICP-MS, which acquires information on the element distribution & iMScope QT MALDI-MS Microscope, which provide information on the compound distribution.

Clinical Imaging with LA-ICP-MS and MALDI-MS Microscopy

The successful development of effective mRNA-based vaccines to fight Covid-19 has created a boost in acceptance and application of this strategy for other vaccines and also related drug products. Consequently, the demand to analytically characterize these new modalities has risen, challenging the state-of-the-art analytical approaches to keep pace.
In this webinar we showcase how novel techniques together with modern instrumentation and data analysis software can further the understanding of this new drug class, thereby ensuring the efficacy and safety of the drug product.
The identity and sequence validation of the mRNA after limited endonuclease digestion and mass spectrometric sequence confirmation is demonstrated. Tips and tricks for successful method development and data handling in Biopharma finder software will be presented, including the use of the software to address 5’-Capping and poly(A) tail characterization.
We hope to see you there! 
<h3>Learning points:</h3>
<ul>
<li>How novel techniques together with modern instrumentation and data analysis software can further the understanding of this new drug class, thereby ensuring the efficacy and safety of the drug product.</li>
<li>Demonstration of identity and sequence validation of the mRNA after limited endonuclease digestion and mass spectrometric sequence confirmation</li>
<li>Tips and tricks for successful method development and data handling in Biopharma finder software</li>
</ul>
Who should attend:
<ul>
<li>Biopharmaceutical Research Scientists </li>
<li>Analytical Scientists from Biopharma companies working on or interested in oligonucleotide-based therapies. </li>
<li>PhD students in any field of biotherapeutic drug development </li>
<li>Scientists looking to advance knowledge of oligonucleotide analysis.</li>
</ul>
<blockquote>
Presenter: Dr. Alexander Schwahn (European Application Expert for BioPharma Industry, Thermo Fisher Scientific)
</blockquote>
<blockquote>
Presenter: Aude Croguennec (Moderator, Regional Marketing Manager, Thermo Fisher Scientific)
</blockquote>

Thermo Fisher Scientific: Characterization of mRNA-based therapeutics with (U)HPLC and HRAM mass spectrometry

Characterization of mRNA-based therapeutics with (U)HPLC and HRAM mass spectrometry

In this webinar we showcase how novel techniques together with modern instrumentation and data analysis software.

mRNA-based therapeutics with (U)HPLC and HRAM MS

Live from the Lab presents a unique and exciting opportunity to learn about the new Thermo Scientific Orbitrap Astral mass spectrometer and discover how it can unleash the proteomics potential of your laboratory.
Fitting seamlessly into our high-throughput proteomics workflow, the system offers the ability to obtain deeper protein coverage quicker and with higher sensitivity. As well as the mass spectrometer, we will also consider the key issues of sample preparation, chromatography and data analysis.
The event will be hosted by the Thermo Fisher Scientific factory in Bremen but will be live-streamed to locations across the whole EMEA region. The agenda will include presentations from designers of the new system, including Professor Alexander Makarov, as well as leading scientists who will present their thoughts and their data on the new instrument and it&#39;s potential for a range of scientific fields including cancer research and precision medicine.
In addition to the Orbitrap Astral we will showcase the complete portfolio of instruments offering the solution of an Orbitrap for every lab!
<h3>Agenda:</h3>
<h5>10:00-10:10 Welcome and introduction</h5>
<ul>
<li>Thomas Moehring, Thermo Fisher Scientific</li>
</ul>
<h5>10:10-10:40 Velocity- A benchmarking workflow for high throughput DIA label-free quantification</h5>
<ul>
<li>Julia Kraegenbring, Thermo Fisher Scientific</li>
</ul>
<h5>10:40-11:10 Rethink what’s possible with the Orbitrap™ Astral ™ Mass Spectrometer</h5>
<ul>
<li>Alexander Makarov and Hamish Stewart, Thermo Fisher</li>
</ul>
<h5>11:10-11:40 DIA with non-isobaric multiplexing on a novel high-resolution platform</h5>
<ul>
<li>Sofia Steigerwald, Mann Lab, Max Planck Institute of Biochemistry, Institute of Biochemistry</li>
</ul>
<h5>11:40-12:10 Coffee Break and Q&amp;A session</h5>
<h5>12:10-12:40 Plasma proteomics with unprecedented depth and scale</h5>
<ul>
<li>Markus Vossman, Seer Inc.</li>
</ul>
<h5>12:40-13:10 Sensitive and robust high-throughput workflow for quantitative and qualitative single cell/single cell-like analysis</h5>
<ul>
<li>Bernard Delanghe, Thermo Fisher Scientific</li>
</ul>
<h5>13:10-13:40 Single-cell proteomics on the Orbitrap Astral MS for the exploration of cell heterogeneity</h5>
<ul>
<li>Benjamin Furtwängler, Technical University of Denmark</li>
</ul>
<h5>13:40-14:30 Lunch and Q&amp;A session</h5>
<h5>14:30-15:30 Laboratory/ Factory Plus Tour Orbitrap Astral Show and Tell</h5>
<h5>15:30-17:00 Networking discussions</h5>

Live from the Lab

Learn about the new Thermo Scientific Orbitrap Astral mass spectrometer and discover how it can unleash the proteomics potential of your laboratory.

Mass Spectrometry Imaging (MSI) is a technique that allows chemical information to be obtained directly or via the use of matrices from a wide range of surfaces. MS Imaging provides information on the spatial distribution of molecules at or near the surface. Imaging provides beautiful and information-rich images that allow scientists to answer the fundamental question: “Where is this component in my sample?”
In this webinar series, we will examine the basics of MS imaging, compare the techniques of untargeted and targeted MS Imaging and the information that can be gained from each, and end with an interview from Dr. Ryan Leib (Stanford University) and Dr. Roy Martin (Waters Corporation) on the practicalities of setting up a MS Imaging Core lab.
Who Should Attend: Any scientist, lab managers or lab directors looking to expand (or refresh) their knowledge of MS Imaging.
<h3>Part One – October 10th, 2023: What is mass spectrometric imaging?</h3>
In this session, we will examine the types of MS imaging techniques on the market and the platforms on which they can be run. We will also discuss the types of data and information that MS imaging can provide and what imaging provides a user that other mass spectrometric techniques cannot.
<blockquote>
Presenter: Bindesh Shrestha (Senior Application Support Scientist, Waters Corporation)
</blockquote>
<blockquote>
Bindesh Shrestha, PhD., is an expert in the field of imaging mass spectrometry and ambient ionization. He completed his graduate work at the George Washington University and is currently employed with the Waters Corporation. In Waters, Bindesh supports academic grant efforts with biomedical applications, such as imaging MS and metabolomics. Bindesh has co-authored about three dozen peer-reviewed articles in leading journals, such as Angewandte Chemie, Analytical Chemistry, Analyst, Nature Methods. In the last two years, he edited a book on single-cell metabolism with Springer and published an introductory book on imaging mass spectrometry with Elsevier.
</blockquote>
<blockquote>
HOST: Kieron Faherty, Ph.D. (Separations and Mass Spectrometry Field Marketing Manager, Waters Corporation)
</blockquote>
<blockquote>
Kieron Faherty is the Separations and Mass Spectrometry Field Marketing Manager for the Americas at Waters Corporation. He received his B.Sc. (Hons) in Chemistry from the University of Reading (Reading, Berkshire, UK) and his doctorate in Chemistry from the University of Massachusetts (Amherst, MA). He has held several field-based positions at Waters, most recently as a Field Applications Specialist focused on biopharmaceutical applications using Time-of-Flight mass spectrometry instrumentation.
</blockquote>

Waters Corporation: What is Mass Spectrometry Imaging?

What is Mass Spectrometry Imaging?

We will examine the types of MS imaging techniques on the market and the platforms on which they can be run.

LCMS webináře se zaměřením na LC/MS - strana 74