Charged Aerosol Detection Symposium - Session 1
Basics and beyond
A wide range of detection options exist for liquid chromatography, but each has limitations. Charged aerosol detection (CAD) offers an alternative, universal detection option.
Presentations:
Basics and beyond
Paul Gamache and Chris Tuczemskyi - Thermo Fisher Scientific
Polysorbate analysis in drug products
Georg Schuster - Coriolis Pharma
CAD in Pharmaceutical Analysis – Selected applications and optimization strategies
Ruben Pawellek - Institut für Pharmazie und Lebensmittelchemie University of Wuerzburg
High Throughput Analysis (HTA) for small molecule libraries with the Thermo Scientific Vanquish Duo UHPLC system
Thomas Dann and Matthew Gill - Charles River Laboratories
Roundtable and Q and A discussion
Learning points:
- Learn how charged aerosol detection works
- What makes charged aerosol detection so powerful
- What benefits it offers
- What applications are ideal for charged aerosol detection?
Who should attend:
- Laboratory managers and Directors
- Technology leaders
- Principal scientists
- Laboratory analyst
Presenter: Chris Tuczemskyi (Applications & Technical Support Specialist, Thermo Fisher Scientific)
Chris Tuczemskyi is a chromatography specialist at Thermo Fisher Scientific, based in Cambridge, UK. After spending a number of years building up his experience with chromatography instruments in a water testing laboratory, he joined Thermo Fisher Scientific in 2014 as a chromatography service engineer for Unity Lab Services. Here he developed his passion for supporting customers using HPLC and in 2018 moved into the application specialist team. As a chromatography specialist, his role includes working with customers in developing applications to help to enable them to make the world healthier, cleaner and safer. In 2009, Chris graduated from the University of Essex in Biochemistry (Bsc Hons).
Presenter: Georg Schuster (Coriolis Pharma)
Georg Schuster is senior scientist and group leader at Coriolis Pharma, a science-driven contract research organization, where he focusses on protein characterization and analytic method development for biopharmaceuticals with LC and CE based separation techniques and polysorbate characterization via LC coupled to charged aerosol detection. Georg has received his PhD degree in analytical chemistry from the University of Vienna, Austria, in the field of HILIC stationary phase development and further worked as post-doctoral scientist at the Australian Centre for Research on Separation Science, Tasmania. Prior to working at Coriolis Pharma (2016), he was a scientist engaged in protein separation method development at Novo Nordisk, Denmark.
Presenter: Ruben Pawellek (PhD Student, University of Wuerzburg, Germany)
Ruben Pawellek received his pharmacy degree at the university of Wuerzburg in 2016, followed by one year of practical training in the quality control unit of Boehringer Ingelheim and in a public pharmacy. Since 2017, he pursues his PhD studies in pharmaceutical chemistry at the university of Wuerzburg. His research is mainly focused on the application of HPLC-CAD in pharmaceutical analysis and on the optimization of the detector’s performance. In 2020, he completed a three-year professional training in pharmaceutical analysis.
Presenter: Thomas Dann (Analytical Scientist, Charles River Labs)
Graduating from the University of East Anglia with an MChem degree, I went on to complete a PhD there focusing on electroanalytical chemistry, where I synthesised organometallic compounds, characterising them by NMR, mass spectrometry and electrochemical techniques. From this I moved into industry working in a Compound Management lab where the role included QC by LCMS for newly solubilised compounds. Building on this experience, I then progressed onto a full analytical science role at Charles River.
Presenter: Matthew Gill (Charles River Labs)
Moderator: Frank Steiner (Senior Manager of Product Applications, Thermo Fisher Scientific)
Frank Steiner is Senior Manager of Product Applications and coordinates HPLC based scientific collaborations in Thermo Fisher Scientific as scientific advisor. He joined Dionex Corporation in 2005, now a part of Thermo Fisher Scientific, and had been manager in various HPLC marketing functions. Frank received his PhD degree in chemistry in 1995 from Saarland University in Saarbruecken, Germany where he became assistant professor in 1997 and associate professor in 2003, after his postdoc at the nuclear research center in Saclay, France in 1996. Frank published more than 30 publications in refereed journals and more than 10 text book chapters on HPLC topics.
Moderator: Paul Gamache (Director Research Development, Thermo Fisher Scientific)
Paul is an analytical chemist who joined Thermo Fisher Scientific in 2011 through acquisition of Dionex Corporation. He is a Director of R &D responsible for development of analytical technologies with primary focus on charged aerosol detection (CAD) and electrochemical detection (ECD) for LC. Prior to joining Dionex in 2009, Paul led the development of first and second generation Corona CAD products. He has published more than 50 articles and book chapters and was co-awardee of an NIH Roadmap grant for development of hyphenated EC and LC-MS technologies for metabolomics research. Paul is editor and contributing author to the book “Charged Aerosol Detection for Liquid Chromatography and Related Separation Techniques” published in 2017 by John Wiley & Sons, Inc.
