Column Chemistry Compass: Navigating the Agilent HPLC and UHPLC Column Landscape

Choosing the right HPLC column can be challenging given the wide range of stationary phases, particle technologies, and column dimensions available today. Whether you’re aiming to accelerate your separations, extend the performance of an older LC system, or unlock the full capability of a modern Agilent UHPLC platform, selecting the optimal column is key to achieving reliable, reproducible results.
In this webinar, we’ll explore how Agilent’s column technologies—from traditional fully porous ZORBAX materials to advanced superficially porous InfinityLab Poroshell particles—can be strategically matched to your instrument and your analytical goals. We’ll discuss how particle size and column dimensions influence efficiency and back pressure, helping you balance resolution, speed, or instrument compatibility.
Beyond standard C18 phases, we’ll highlight a range of Agilent bonded phase chemistries designed to enhance selectivity and help you make informed choices for your next HPLC or UHPLC separation.
Speaker: Mark Powell
Mark Powell is an Applications Engineer located at Agilent’s Little Falls site in Wilmington, DE. Before joining Agilent in 2011, Mark worked in the pharmaceutical industry synthesizing, purifying and analyzing drug candidates. He provides applications assistance and technical support for Agilent’s HPLC columns and consumables.
