Automation Of Dissolution Process With The Merel dissoBOT System

In this webinar we will explore the Merel, dissoBOT system, a pioneering technology in the pharmaceutical testing landscape, introducing the first fully automated dissolution system featuring clip-on/off capabilities.

This state-of-the-art system simplifies the dissolution process by enabling automatic sequential operations—cleaning, media dispensing, and sample introduction without interfering with the ongoing dissolution process. Designed to work seamlessly with established systems such as the Agilent 850-DS Dissolution Sampling Station and the 708-DS Dissolution Apparatus, dissoBOT enhances efficiency and reproducibility. The advanced automation facilitated by collaborative robotics allows for extended operational cycles and minimal setup time, with a clip-on procedure completing in less than a minute.

This webinar will detail the operational principles, components like the Dosage Delivery Module (DDM), and the integration capabilities of the dissoBOT with current dissolution apparatuses, ensuring precise media dispensing and accurate sample analysis. Participants of this webinar will gain in-depth knowledge and practical insights into the automation of the dissolution testing process using the Merel dissoBOT system.

Key learning objectives include:

• Understanding the foundational technology behind the dissoBOT's clip-on/off capability and its integration with existing dissolution systems.
• Exploring the automated functions of the dissoBOT, including sequential media dispensing, cleaning, and sample introduction, and how these operations enhance testing efficiency and accuracy.
• Learning about the compatibility of the dissoBOT with common dissolution apparatuses like the Agilent 708-DS and the 850-DS Dissolution Sampling Station.
• Gaining insights into the process enhancements brought by the dissoBOT, such as reduced manual intervention, increased reproducibility, and streamlined workflow.
• Discovering the technical specifics of the system components, including the Dosage Delivery Module, dissoDOSE technology, and automated sample collection methods.
• Understanding the impact of dissoBOT on pharmaceutical quality control and how it can lead to more reliable and faster dissolution testing results.

Presenter: Owain McKenzie (Dissolution Business Team Manager EMEA, Agilent Technologies)

Owain McKenzie is currently the EMEA Dissolution Business Team Manager with Agilent. Since 2000 Owain has performed analytical testing, supervised pharmaceutical laboratories, run sales teams, and managed customer support teams with GSK, VanKel, Erweka, Varian and Agilent. Primary responsibilities have been in the fields of product release, stability, product development and support, LC, MS & UV. Dissolution method development and validation, instrument qualification and calibration, technology transfers and training. Current activities since 2010 have focused on providing method and technical application support for dissolution and drug release testing in the pharmaceutical industry as well as Agilent R&D, Marketing and Sales teams. Owain provides numerous talks and publications on dissolution related techniques and topics including publication of the Immediate Release Newsletter, and Dissolution Discussion Group (DDG). He received his MSc degree in Chemistry from the University of Leeds, UK, and is an active member of both the Royal Pharmaceutical Society and the Royal Society of Chemistry in London UK.

Presenter: Nejc Zorko Horvat (Product Manager, Merel)

Nejc Zorko Horvat has been working in the field of dissolution, UV-Vis-NIR, and fluorescence spectroscopy for 15 years. He manages domestic and international projects, including installation, qualification, and customer training on novel and complex systems. With extensive experience supporting customers in GMP environments and numerous compliance trainings, his main focus is on the pharmaceutical market.

His background in IT allows him to provide solutions for both hardware and local or networked software. Since 2024, he has been managing the complete portfolio of Merel Instruments in foreign markets. His role includes presenting at international seminars, fairs, and specialized events, conducting online product demos, managing dealers, and visiting customers.