Why Biphenyl should be the go-to for clinical and toxicological analysis

Within clinical and toxicological laboratories the bulk of work requires the testing of target molecules and their metabolites in complex matrices like blood, plasma or urine with urgency, accuracy and precision. Liquid chromatography methods facing these challenges often require the separation of many physically similar, or isobaric compounds, which poses a particular challenge as isobaric compounds featuring the same product/precursor ions require chromatographic separation to allow accurate characterisation and quantification.
In this webinar we look to discuss why Biphenyl type LC columns should be the go-to chemistry for toxicological and clinical workflows; provided real world solutions to complex chromatographic challenges looking at neurotransmitters, drugs of abuse, and hormones.
In this webinar we will:
- Provide an overview of clinical and toxicological markets (workflows, instrumentation and challenges faced)
- Discuss how biphenyl phases retain, and how to benefit from this mechanism
- Learn best practices for successful utilisation of biphenyl columns
- Review example chromatograms for Clinical and Toxicological markets
- Look at ProEZ LC Chromatogram Modeller and discuss how this can speed up your method development
