Introduction to Multi-Angle and Dynamic Light Scattering: Applications in Biotherapeutics
Light scattering techniques like MALS and DLS offer critical insights into biotherapeutic development by enabling the assessment of absolute molar mass, aggregation, colloidal stability, and structural modifications.
This webinar will provide an introduction to SEC-MALS and DLS, highlighting their applications for characterizing monoclonal antibodies (mAbs), conjugated proteins, and adeno-associated viruses (AAVs). Learn how cutting-edge instrumentation delivers absolute molecular weight, size, and composition measurements for biotherapeutics.
Key Learning Objectives:
- Fundamentals of Multi-Angle and Dynamic Light Scattering
- Application of advanced light scattering techniques (DLS, SEC-MALS) for biopharmaceutical characterization
- Understanding the limitations of SEC/GPC and how does MALS and DLS address these challenges
Who Should Attend:
- Researchers interested in learning more about light scattering
- Any scientist working in the development or quality control space
- Researchers with chromatography systems that need accurate and precise molar mass and size distribution results
Presenter: Udayabagya (Bud) Halim (Sr. Marketing Analyst)
Bud Halim is a Senior Marketing Analyst at Wyatt Technology, bringing a wealth of scientific expertise to the analytical instrumentation field. He earned both his B.S. and Ph.D. in Physical Chemistry from UCLA, where his passion for science began. Bud started his career in academia as an adjunct professor, teaching Biochemistry, Analytical Chemistry, and Physical Chemistry, while also contributing as an editor and author to several laboratory manuals. He later transitioned into the scientific instrumentation industry, serving in roles including applications scientist, with hands-on experience in the characterization of batteries, semiconductors, and the stability of biologics, including LNPs and viral vectors.
