Non-targeted PFAS screening using high sensitivity QToF LCMS with novel, PFAS-specific data processing

PFAS in Focus

Welcome to the PFAS in Focus, a comprehensive and exclusive 10-parts webinar series sponsored by Shimadzu, covering the basics and beyond about the analysis of Per- and Polyfluoroalkyl Substances (PFAS) in the environment. In these five webinars, our experts will demonstrate the suitability of various analytical techniques, such as LCMS, GCMS, CIC, and QTOF, for PFAS testing.

Join our experts, live or on-demand after the original air date, to demystify the challenges of PFAS analysis and gain the insights you need to:

• Manage PFAS contamination in your laboratory.
• Master standardized methods for PFAS testing.
• Discover new analytical workflows to maximize the performance of your instruments (LC-MS/MS, GCMS, CIC, QTOF) for PFAS analysis.

Who should attend:

• Environmental industry professionals and academics currently working on PFAS analysis or looking to establish the application in their labs.
• Representatives from drinking and wastewater utilities.
• LC–MS users from any field interested in expanding their applications to include PFAS testing.

Part 03: Non-targeted PFAS screening using high sensitivity QToF LCMS with novel, PFAS-specific data processing

Targeted detection of PFAS using triple quadrupole mass spectrometry provides a sensitive but incomplete picture of residual PFAS contamination due to the large number of unknown isomers and chemicals. Non-targeted screening using high resolution LC mass spectrometry with state-of-the-art data processing can detect and identify the full range of flourinated compounds without detection bias. 

We will present our newly developed untargeted LCMS method using a sensitive and high mass accuracy QTof mass spectrometer, and a novel data processing approach specific for per- and polyfluorinated substances.

We will host a Q&A session after the presentation to address any questions or comments.

Presenter: Jeff Dahl, PhD (Senior Applications Scientist, Shimadzu Scientific Instruments)

Jeff earned a BS in biochemistry from the University of Minnesota and a PhD in Medicinal Chemistry from the University of Illinois at Chicago. Jeff specializes in LCMS analysis including detection of pesticides, drugs of abuse, high resolution accurate mass measurement, MS imaging, and non-targeted data processing. He is a senior application scientist at Shimadzu, where he has worked since 2010.

Presenter: Ruth Marfil-Vega, PhD (Sr Market Manager – Environmental, Shimadzu Scientific Instruments)

Dr. Ruth Marfil-Vega has 20 years of expertise in environmental chemistry and engineering in the US and Europe. She has worked with the EPA and the utilities industry to design and execute comprehensive solutions for addressing new environmental and water quality issues, including PFAS, regulated and unregulated DBPs, and other emerging contaminants. Since Ruth joined Shimadzu five years ago, she has continued to work with environmental stakeholders to ensure that analytical instrumentation and workflows support their success. She earned a BSc in Chemistry from the University of Valladolid (Spain) and a PhD in Environmental Science and Engineering from the University of Cincinnati.