Rethinking Karl Fischer Titration: How Smarter Algorithms Tackle Complex Water Determinations
By attending this discussion, you will:
- Discover how automated control algorithms enhance precision and reduce titration times without compromising accuracy.
- Understand how advanced drift management tools ensure reliable results, even in demanding conditions.
- Explore how modern titration systems address safety and sustainability goals with features such as remote operation and support for greener solvents.
Event Overview
For nearly a century, Karl Fischer titration has been the trusted method for determining water content in products ranging from pharmaceuticals to processed snacks. However, even reliable techniques face challenges. For example, antibiotics can be difficult to analyze due to their limited solubility in conventional solvents, often requiring additional heating steps to ensure accurate measurements. Environmental factors, such as humidity, can further complicate workflows by introducing drift and reducing precision.
Join us for an expert discussion exploring how the latest innovations in Karl Fischer titration technology tackle these issues head-on. Panelists Nicolas Monney (Application Chemist, Mettler-Toledo) and Matteo Stefanoni (Senior Scientist, Mettler-Toledo) will answer questions related to advancements such as high-resolution sensors, low-dead-volume burets, and modular designs that improve accuracy, safety, and workflow efficiency. Learn how the EVA KF Titrator’s Fast Feedback Algorithm redefines titration workflows by adapting in real time to reaction conditions.
Who Should Attend:
- Scientists, lab managers, and analysts working in water determination across industries, including pharmaceuticals, food, biopharma, and materials science.
- Professionals seeking practical solutions to improve accuracy, efficiency, and reproducibility in Karl Fischer titration workflows.
- Anyone facing challenges with complex samples, drift, or evolving regulatory requirements in moisture analysis.
Share Your Challenges Across Industries
Water determination plays a pivotal role in advancing quality and innovation. Do you struggle with reactive compounds, complex sample matrices, or meeting regulatory demands? This event offers the chance to have your specific questions addressed by experts.
Submit your questions through the webinar registration form, and our panel will address selected challenges during the broadcast.
Presenter: Nicolas Monney (Application chemist, Mettler-Toledo)
Nicolas Monney holds a Ph.D. in Physical Chemistry. His research focused on studying electron transfer through proteins using low-temperature spectroscopy and ab-initio simulations.
Nicolas began his career at Mettler-Toledo nearly ten years ago, taking on the role of Applications Specialist for Titration. In this role, he develops innovative titration applications and collaborates closely with the R&D department to facilitate the development of new products. Additionally, he supports the sales force of Mettler-Toledo and its partners on titration projects worldwide
Presenter: Matteo Stefanoni (Senior Scientist, Mettler-Toledo International)
Matteo is a scientist with a strong academic background and experience in the fields of chemistry and material science. He earned his Master’s degree in Chemistry from the University of Milano and a PhD from ETH Zürich, focusing on electrochemistry. After completing his doctoral studies, Matteo spent two years as a postdoctoral researcher, further enhancing his expertise in the field. Currently, Matteo serves as a Senior Scientist at Mettler-Toledo, where he has spent the last five years developing advanced control algorithms for automatic titration instruments. Notably, he has dedicated four of those years to developing an innovative model-based control algorithm for Karl Fischer titration analysis, significantly improving the efficiency of this analytical technique.
