Tackling separation challenges with advanced asymmetric field flow fractionation: Future directions in technology
For pharmaceutical scientists and materials researchers looking for precise ways to separate and analyze complex mixtures—like nanoparticles, proteins, and polymers—Wyatt Technology offers advanced Asymmetric Field-Flow Fractionation (FFF). Unlike conventional separation techniques, FFF technology delivers gentle separation for fragile complexes and is ideal for large molecules like lentivirus or highly branched polymers that are prone to exit in the void volume of many packed columns.
Once labeled as finicky and difficult to use, we will share the most recent advances in instrumentation and software that bring streamlined workflows and highly reproducible results. Join us and discover the latest innovations in FFF technology and see how it could be applied to enhance your research.
Key Learning Objectives:
- Understand the latest advancements in Field-Flow Fractionation technology and how the most recent innovations improved separation
- When to choose an FFF instrument over or in addition to conventional packed-bed columns for separation
- Explore the difference between a fixed-height channel and variable height channel and why does it matter
- Explore real-world applications of FFF in pharmaceuticals, biotechnology and materials science
Who should attend:
- Pharmaceutical scientists - Involved in drug development, especially those working with nanoparticles, virus-like particles, vaccines and fragile protein complexes
- Analytical Chemists – Focused on advanced separation techniques for complex mixtures such as polymers, nanoparticles, and biomolecules in both research and industry
- Polymer Scientists – Interested in separating and understanding molecular size distribution, branching, and polydispersity in polymer systems
Presenter: Steve Trainoff, Ph.D. (Waters | Wyatt Technology)
Dr. Trainoff has an undergraduate degree in physics from Caltech and a Ph.D. from UCSB. He develops analytical instruments that are used to characterize macromolecules using a variety of analytical techniques including static light scattering, dynamic light scattering, electrophoretic light scattering, differential viscosity, and refractive index detection. He has also made fundamental contributions to separation science through the development of Neon Eclipse Field Flow Fractionation instruments. Together they can be used to measure molar mass, molecular size, charge, diffusion constants, aggregation state, and conformation. This technology is used by a very diverse set of industries including pharmaceutical and vaccine research, synthetic polymers, nanotechnology, and material science. He is the author of over 40 US patents.
