Introduction to Compact Liquid Chromatography
This course is designed to introduce those familiar with analytical-scale HPLC to capillary (or “nano”) liquid chromatography. Although both techniques are based on the same fundamental principles, capillary LC delivers a number of distinct advantages with appropriate use.
Commercial instrument options, as well as the basics of preparing your own capillary LC columns, will be described. Because one of the most prominent uses of capillary LC is its coupling to mass spectrometry for complex biological sample analysis, special attention will be given to this important area. Both academic and industrial researchers will be able to apply the information gained through this course to successfully use this essential technique.
After completing this course, participants will be able to:
- Understand the differences between analytical and capillary scale LC
- Describe the fundamentals of capillary LC column preparation
- Determine the best detection modes for a given application
- Explain the advantages of coupling capillary LC with mass spectrometry and how to approach method development using capillary LC-MS
- Identify best practices for the use of capillary LC to solve analytical challenges
Who Should Attend?
Scientists, chemists, analytical researchers, lab directors and managers, VPs and directors of QC/QA, lab owners
Presenter: Dr. James Grinias (Professor, Department of Chemistry & Biochemistry, Rowan University)
James Grinias is a Professor in the Department of Chemistry & Biochemistry at Rowan University in Glassboro, New Jersey, USA. Dr. Grinias has a number of research interests focused on chemical separations and microfluidics, both at the fundamental level and for the analysis of biological systems. He is the recipient of the 2021 American Chemical Society Satinder Ahuja Award for Young Investigators in Separation Science and the 2022 LCGC Emerging Leader in Chromatography. At Rowan, he teaches courses in general, analytical, and bioanalytical chemistry while also conducting research on UHPLC column performance and instrument miniaturization.
Presenter: Greg Ward (CEO, Axcend)
Greg Ward serves as the CEO of Axcend, renowned for its portable high-performance liquid chromatography (HPLC) systems. Greg has over 30 years of experience in the technology and scientific instrumentation sectors. Before joining Axcend, Greg held technical and marketing roles at Hewlett Packard and Agilent Technologies. His leadership at Axcend has been pivotal in advancing the development and commercialization of the Axcend Focus LC®, a compact and eco-friendly HPLC system that has revolutionized the field by offering customers portability, ease of use, and reduced operational costs. Axcend has made significant strides in making high-quality chromatographic analysis accessible and convenient for various industries, including pharmaceuticals, environmental monitoring, and chemical manufacturing. Greg’s vision and dedication continue to push the boundaries of scientific analysis, making him a key leader in the field of compact liquid chromatography.
