Benefits of Adopting Routine Mass detection in Traditional LC-UV Workflows for the Analysis of Synthetic Oligonucleotides
Oligonucleotides continue to gain in popularity for a wide range of applications, from gene-based therapeutics to targeted crop protection.
Robust analytical tools and solutions are required to speed up development to meet compliance and regulatory requirements.
Sometimes traditional chromatographic LC-UV generated data is simply not enough, and orthogonal detection techniques like LC-MS provide scientists with greater confidence in getting the right result first time.
Join us for this demonstration of a typical oligonucleotide impurities workflow using the ACQUITY Premier system with the ACQUITY QDa Mass Detector.
Key learning objectives:
- LCMS System overview and key hardware features
- Practical tips and maintenance of the ACQUITY QDa detector
- Impurities workflow overview, from sample setup, processing and reporting data in compliant Empower CDS software
- Benefits of mass data for peak tracking and identification
Who should attend?
- Scientists in pharmaceutical, chemical, clinical, contract research organizations (CRO), cosmetics and agrochemical industries, universities, and governmental laboratories
- Chromatographers wanting to transition to LC-MS from traditional LC-UV workflows
- Anyone with an interest in mass spectrometry who wants to learn more
- If you have any questions or would like to learn more please get in touch.
Presenter: Victoria van Kuijk (Principal Applications Chemist, Waters Corporation)
Victoria van Kuijk works for the Waters UK and Ireland Demo lab, based in the South of the UK. Victoria is an experienced scientist specializing in LC instrumentation and separations method development, providing application consultation and support (Pharma/BioPharma).
Through previous roles within Waters, Victoria has acquired extensive experience and knowledge of Waters Empower CDS. She holds a Bachelor of Science (Hons) degree in Applied Chemistry from Nottingham Trent University.
