Chapter 3: Inside the technical note

Join us for an exceptional live event that will take you behind the scenes of technotes, with insights and expertise from three remarkable speakers. Get ready to ignite your curiosity and expand your knowledge in this unique webinar experience.

Webinar highlights:

Technical note 1: Development of an acetylcholinesterase biochemical assay using the SCIEX Echo® MS system (Speaker: Jacob MacCabe)

• Discover the critical role of biochemical assays in drug discovery, their significance in evaluating safety liabilities, and how mass spectrometry revolutionizes enzyme target screening. Jacob MacCabe, a senior scientist at SCIEX, will unveil the power of the SCIEX Echo MS system in a routine acetylcholinesterase (AChE) biochemical safety assay.

Technical note 2: Enhanced drug metabolite identification using collision-induced dissociation (CID) and electron-activated dissociation (EAD) (Speaker: Rahul Baghla/ Eshani Nandita Galermo)

• Learn about a software-assisted approach for metabolite identification using the ZenoTOF 7600 system and Molecule Profiler software. By combining CID and EAD data, our speakers will show you how to increase confidence in metabolite structure assignments.

Technical note 3: A sensitive method for the quantitation of bimatoprost in human plasma (Speaker: Lakshmanan Deenadayalan)

• Uncover a highly sensitive method for quantifying the ocular drug, bimatoprost, in human plasma. Lakshmanan Deenadayalan, an Application Support Specialist at the Indian Innovation Center (IIC), SCIEX, will demonstrate a simple liquid-liquid extraction sample preparation that achieves a lower limit of quantitation (LLOQ) of 0.5 pg/mL with %CV < 3%.

Presenter: Rahul Baghla (M. Pharma, MBA, Manager Pharma Applications, SCIEX)

Presenter: Lakshmanan Deenadayalan (Application Support Specialist, Indian Innovation Center (IIC), SCIEX)

Presenter: Eshani Nandita (Global Biopharma Quant Tech Marketing Lead, SCIEX)

Presenter: Jacob W. McCabe (Senior scientist at SCIEX specializing in the Echo MS system)