Smart Method Development using the Empower Method Validation Manager and the Sample Set Generator
Robustness testing is a measure of a method’s ability to remain unaffected by the minor changes of chromatographic parameters. The robustness multivariable design of experiments (DoE) can be used to study the effect of individual parameters and their interaction on the chromatographic resolution between peaks.
The Empower Sample Set Generator (SSG) can be used to automatically create a sample set method, which includes instrument methods, and method sets required to perform the entire study in one run. The Effect Plots generated by the Method Validation Manager clearly show which parameters have the greatest effect on method performance and provides knowledge for establishing a set of controls to assure a method meets the expected criteria during routine use.
Key points of discussion will be:
Using the Sample Set Generator with the Method Validation Manager option to easily create Sample Sets needed for the Robustness test
The Robustness multivariable design of Experiments (DoE) is easily created to study the effect of parameters and their interaction on chromatographic resolution between peaks
The Effect Plot in the Report Publisher can be used to clearly shows which parameters have the greatest effect on method performance
Join us for a live discussion as we explore Empower 3.8.0. As always, don’t forget to bring your questions for this exclusive opportunity to ask our experts anything about Empower Software
Presenter: Neil Lander (Principal Product Manager, Waters Corporation)
Neil has worked for Waters Corporation since 1994 and has held a variety of positions including Technical Support Specialist, Technical Trainer, Manager Customer Education and currently, Principal Marketing Manager focusing on Informatics solutions. He provides internal support for Empower Chromatography Data System and is focused on developing laboratory software solutions that help organizations achieve their scientific and operational objectives. Prior to joining Waters, he was an analytical chemist where he gained experience in both the cosmetics and specialty chemical industries.
