How to Achieve Accurate Water Content Results with Karl Fischer Titration

Three Webinars and a Roundtable with Experts from Merck KGaA, Darmstadt, Germany, Metrohm & Mettler Toledo

A Week Dedicated to Karl Fischer Titration!

Karl Fischer titration is still the most used, most accurate, and fastest method to determine water content in all kinds of sample matrices. This titration week covers different aspects that need to be considered when determining the water content in products, raw materials, and other substances. Experts from the life science business of Merck KGaA, Darmstadt, Germany, Metrohm AG, and Mettler Toledo will present and discuss different steps of the Karl Fischer titration process and how to improve it. Learnings include:

• Karl Fischer titration process and tips for how to improve it
• Karl Fischer oven method and its advantages
• Reference materials to use for titer determination, instrument check, and result verification
• Parameters needed to validate a Karl Fischer titration application
• News and future aspects of Karl Fischer titration

How to Achieve Accurate Water Content Results with Karl Fischer Titration

Transparent and accurate analysis results are an important prerequisite for meeting your customers' quality expectations on products, raw materials and processes. A central analytical parameter is the water content. Water can influence stability, durability, permeability, or consistency of materials, or the energy consumption, yield, and safety in production processes. Therefore, exact water determination is necessary in a wide variety of industries. The Karl Fischer titration method is still the most used, fastest, and most precise method for measuring water content to get accurate, transparent, and comparable results. By attending this presentation, you will learn:

• The difference between Volumetry and Coulometry
• How to improve your Karl Fischer titration process
• The key quality assurance requirement
• How to perform an accurate titer determination
• Tips to avoid failures

Presenter: Bettina Straub-Jubb (Product manager & Lead Expert for Titration at the life science business of Merck KGaA, Darmstadt, Germany)