Need help with Sample Prep for LCMS in the Lab? Making use of the Automated Liquid Sampler you already have on your LCMS
Agilent Technologies: Need help with Sample Prep for LCMS in the Lab? Making use of the Automated Liquid Sampler you already have on your LCMS
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Wait what?! Who knew!? There are so many things that a mass spec can do.
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I've used it for years, yes this may be true.
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I've processed some samples, more than a few.
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But between me and you, I had no idea all the things it could do!
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From sample prep to separation, you just won't believe…
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All of the tips and tricks we have up our sleeve.
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So, take a few minutes, about 15 should do.
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And learn all the things your mass spec can do.
The Automated Liquid Sampler (ALS) you have in your LCMS stack can simplify menial tasks. The parameters available in the ALS setup tab and the Sample Pretreatment tab allow the ALS to perform many labor saving functions related to sample prep for LCMS. Examples of functions like internal standard addition or pre-column derivatization to options to simplify Flow Injection Analysis processing will be discussed.
Presenter: Jim Lau, PhD (HRAMS LC/MS Application Engineer, Agilent Technologies, Inc.)
Jim Lau received his Ph.D. From the University of Colorado. There he worked in the laboratories of Peter Albersheim and Robert Shapiro. This work involved the structure elucidation of plant natural products and, in particular, elucidating the structures of oligosaccharides derived from plant cell wall polysaccharides. This work was done in the early days of LCMS and made use of DLI-LCMS and (at the time) recently invented Thermospray-LCMS.
After the completion of his Ph.D., Jim joined Hewlett-Packard to work on LCMS ionization techniques with Paul Goodley during the early days of Electrospray-LCMS. He then moved to work on field applications and collaborations with Hewlett-Packard’s LCMS customers. More than 30 years later, Jim continues to work with Agilent’s customers in High Resolution Accurate Mass applications of LCMS. While involved in many areas of HRAMS LCMS, his recent work has focused on the area of Screening/Qual&Quant of small molecules and on the high throughput confirmation of oligonucleotide synthesis.