Glycan & Sialic Acid Analysis - So Rapid & So Easy

Glycosylation analysis is an essential part of mAb characterization as they can affect immunogenicity, pharmacokinetics, and pharmacodynamics.

Sialic acid capping at the nonreducing terminal of N- or O-glycans can serve a key role in mediating the effectiveness of therapeutic glycoproteins

Associated challeges for such analyses are:

1. End to end approach System columns, reagents & standards.
2. Senstivity, reproducibility & accuracy
3. Sample throughput"

Presenter: Dr. Nithyakalyani SriRangan (Ph.D. Head of Syngene-CAPS (Center for Advanced Protein Studies) BIRAC funded facility, Syngene international Unlimited)

A recipient of the prestigious Marie Curie, has obtained a Ph.D in Pharmaceutical Biology from the University of Grefswald, Germany. Having core expertise in MS based protein characterization and collaboration experience with clients from UK, France and other Scandinavian countries.