Obtain Increased Sensitivity and Solvent Savings with New 1.5 mm UHPLC Columns
Advanced Materials Technology introduces a new dimension in separations! New 1.5 mm ID UHPLC columns push the performance of UHPLC systems by delivering up to 2x sensitivity and 50% less solvent consumption than 2.1 mm ID columns. Due to their hardware design, these 1.5 mm columns offer ease of implementation allowing for their use on commercial UHPLC instrumentation.
The benefits of moving from 2.1 mm to the new, robust 1.5 mm ID columns will be demonstrated using low molecular weight pharmaceuticals. An additional biopharmaceutical case study will be presented using the LCMS analysis of intact and reduced trastuzumab. The impact of reduced dispersion through LC and LCMS system optimization including proper selection of connecting tubing will also be highlighted.
Key Learning Objectives:
- Learn how using a 1.5 mm ID UHPLC column will provide more sensitivity and 50% less solvent usage
- Understand the impact of extracolumn dispersion on UHPLC separations
- How to successfully implement 1.5 mm ID UHPLC columns into existing workflows
Who Should Attend:
- Scientists looking to increase the sensitivity and gain signal intensity of their analytes in their separations as well as reduce solvent consumption and minimize mobile phase preparation.
- Laboratory managers
- Chromatographers
- New method developers
Presenter: Stephanie Schuster, Ph.D. (Senior Technical Support Scientist, Advanced Materials Technology, Inc.)
Presenter: Jeff Huber (Contributing Editor, C&EN Media Group)
