Development of high speed CYP cocktail inhibition assay using UHPLC-MS/MS
Postery | 2013 | ShimadzuInstrumentace
LC/MS, LC/MS/MS, LC/QQQ
ZaměřeníFarmaceutická analýza
VýrobceShimadzu
Klíčová slovaresorufin, cyp, tolbutamide, nifedipine, cocktail, hydroxy, oxidized, inhibition, assay, uhplc, mephenytoin, speed, development, analytes, substances, bufuralol, odsii, using, high, ddi, clarify, excretion, conventional, nmol, pharmacokinetics, strictly, nce, incubated, evaluations, hydrochloride, promote, excluded, patients, serious, important, liver, affects, shim, nexera, purified, one, without, metabolite, pack, concentration, too, substance, toxic, near, ether
Podobná PDF
Shimadzu Liquid Chromatograph Mass Spectrometer LCMS-8050
2021|Shimadzu|Brožury a specifikace
C146-E232G Liquid Chromatograph Mass Spectrometer LCMS-8050 Speed and Sensitivity Beyond Comparison Continuing the evolution of Shimadzu’s UF technology, Shimadzu introduces the LCMS-8050 triple quadrupole mass spectrometer, offering unparalleled measurement speeds and high-sensitivity performance. High-sensitivity quantitation delivered at high speed Multi-component…
Klíčová slova
switching, switchingufswitching, ufswitchingmrm, mrmufsensitivity, ufsensitivityspeed, speedufscanning, ufscanninghigh, highmpp, mpppolarity, polarityion, ionufsweeper, ufsweeperquantitative, quantitativesensitivity, sensitivitynegative, negativeeven
Shimadzu Liquid Chromatograph Mass Spectrometer LCMS-8050
2019|Shimadzu|Brožury a specifikace
C146-E232F Liquid Chromatograph Mass Spectrometer LCMS-8050 Speed and Sensitivity Beyond Comparison Continuing the evolution of Shimadzu's UF technology, Shimadzu introduces the LCMS-8050 triple quadrupole mass spectrometer, offering unparalleled measurement speeds and high-sensitivity performance. High-sensitivity quantitation delivered at high speed Multi-component…
Klíčová slova
ufswitching, ufswitchingswitching, switchingmrm, mrmufsensitivity, ufsensitivityufscanning, ufscanningspeed, speedhigh, highlabsolutions, labsolutionsufsweeper, ufsweepermpp, mppnexera, nexerainsight, insightpolarity, polarityquantitative, quantitativeeven
High-Throughput In Vitro ADME Analysis with Agilent RapidFire/MS Systems: Cytochrome P450 Inhibition
2020|Agilent Technologies|Aplikace
High-Throughput In Vitro ADME Analysis with Agilent RapidFire/MS Systems: Cytochrome P450 Inhibition Application Note Authors Vaughn Miller Agilent Technologies, Inc. Wakefield, MA, USA Introduction Analysis of cytochrome P450 (CYP) inhibition is an important component of the drug discovery process as…
Klíčová slova
rapidfire, rapidfirenadph, nadphinhibitor, inhibitornaph, naphmidazolam, midazolamremaining, remainingactivity, activityinhibition, inhibitioncyp, cypazamulin, azamulindrug, drugcytochrome, cytochromeritonavir, ritonavirwithout, withoutthroughput
High-Throughput In Vitro ADME Analysis with Agilent RapidFire/MS Systems: Cytochrome P450 Inhibition
2020|Agilent Technologies|Aplikace
High-Throughput In Vitro ADME Analysis with Agilent RapidFire/MS Systems: Cytochrome P450 Inhibition Application Note Authors Vaughn Miller Agilent Technologies, Inc. Wakefield, MA, USA Introduction Analysis of cytochrome P450 (CYP) inhibition is an important component of the drug discovery process as…
Klíčová slova
rapidfire, rapidfirenadph, nadphinhibitor, inhibitornaph, naphmidazolam, midazolamremaining, remainingactivity, activityinhibition, inhibitioncyp, cypazamulin, azamulindrug, drugcytochrome, cytochromeritonavir, ritonavirwithout, withoutthroughput