High-Throughput In Vitro ADME Analysis with Agilent RapidFire/MS Systems: Permeability Assays
Aplikace | 2020 | Agilent TechnologiesInstrumentace
Příprava vzorků, LC/TOF, LC/HRMS, LC/MS, LC/MS/MS, LC/QQQ
ZaměřeníKlinická analýza
VýrobceAgilent Technologies
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High-Throughput In Vitro ADME Analysis with Agilent RapidFire/MS Systems: Permeability Assays
2021|Agilent Technologies|Aplikace
Application Note Pharma and Biopharma High-Throughput In Vitro ADME Analysis with Agilent RapidFire/MS Systems: Permeability Assays Author Vaughn MillerAgilent Technologies, Inc. Introduction During the drug discovery process, permeability assays such as Caco-2 (cell line) and PAMPA (parallel artificial membrane permeation…
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Agilent RapidFire 400 high-throughput mass spectrometry system
2020|Agilent Technologies|Brožury a specifikace
Proven. Rapid. Complete. Agilent RapidFire 400 high-throughput mass spectrometry system 2 Leverage over 14 Years of User-Driven Product Innovation and Proven Application Success Do you want to open new avenues for pursuing small- and large-molecule targets— without using surrogates, radioactivity,…
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Ultrafast Analysis of Metabolic Stability Assays Using Agilent RapidFire High-Resolution MS
2019|Agilent Technologies|Aplikace
Application Note Drug Discovery Ultrafast Analysis of Metabolic Stability Assays Using Agilent RapidFire High-Resolution MS Authors Michelle V. Romm, Nikunj Parikh, and Vaughn P. Miller Agilent Technologies, Inc. Wakefield, MA Yuqin Dai Agilent Technologies, Inc. Santa Clara, CA Abstract The…
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High-Throughput In Vitro ADME Analysis with Agilent RapidFire/MS Systems: Cytochrome P450 Inhibition
2020|Agilent Technologies|Aplikace
High-Throughput In Vitro ADME Analysis with Agilent RapidFire/MS Systems: Cytochrome P450 Inhibition Application Note Authors Vaughn Miller Agilent Technologies, Inc. Wakefield, MA, USA Introduction Analysis of cytochrome P450 (CYP) inhibition is an important component of the drug discovery process as…
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