Evaluating BioAccord System Performance in Late Stage Development and QC Environment – Peptide Mapping Analysis
Technické články | 2020 | WatersInstrumentace
LC/TOF, LC/HRMS, LC/MS
ZaměřeníFarmaceutická analýza
VýrobceWaters
Klíčová slovabioaccord, peptide, mapping, system, inter, late, intra, assays, brief, acquity, mass, abundance, waters, retention, digest, developing, systems, intact, concerted, regulated, stage, relative, within, analysis, technology, peptides, spectrometry, uplc, complementing, reproducible, plus, deviation, based, skilled, performance, protein, class, rda, fluctuation, nistmab, flr, launch, deployment, biologics, use, retrospective, tuv, study, standard, plotting
Podobná PDF
Evaluating BioAccord LC-MS System Performance for Deployment of a Compact, SmartMS-Enabled Biopharma Solution in Late Stage Development and QC Environment – Intact Mass Analysis
2020|Waters|Aplikace
[ TECHNOLOGY BRIEF ] Evaluating BioAccord LC-MS System Performance for Deployment of a Compact, SmartMS-Enabled Biopharma Solution in Late Stage Development and QC Environment – Intact Mass Analysis Henry Shion, Jonathan Pugh, Jill Lord, Yun Alelyunas, Ying Qing Yu and…
Klíčová slova
bioaccord, bioaccordsystem, systeminter, interglycoforms, glycoformsintact, intactfive, fiveintra, intrareproducibility, reproducibilitymajor, majormass, massrsd, rsdsystems, systemsstudy, studybrief, briefabundance
Routine Peptide Mapping Analysis using the BioAccord System
2019|Waters|Aplikace
[ TECHNOLOGY BRIEF ] Routine Peptide Mapping Analysis using the BioAccord System Nilini Ranbaduge, Henry Shion, and Ying Qing Yu Waters Corporation, Milford, MA, USA SmartMS-enabled BioAccord System improves the operational efficiency for routine peptide mapping analysis. GOAL Demonstrate how…
Klíčová slova
bioaccord, bioaccordpurposefully, purposefullypeptide, peptidemapping, mappingsystem, systemaccessibility, accessibilityprotein, proteininformatics, informaticssmartms, smartmsbrief, briefintegrated, integratedflr, flrtuv, tuvacquity, acquityunifi
Analysis of Antibody Drug Conjugates (ADCs) by Native Mass Spectrometry on the BioAccord System
2019|Waters|Technické články
[ TECHNOLOGY BRIEF ] Analysis of Antibody Drug Conjugates (ADCs) by Native Mass Spectrometry on the BioAccord System Henry Shion, Ying Qing Yu, and Weibin Chen Waters Corporation, Milford, MA, USA Drug-to-Antibody Ratio (DAR) determination of Lys and Cys conjugated…
Klíčová slova
bioaccord, bioaccordconjugated, conjugatedadc, adcdar, daradcs, adcsnative, nativedrug, drugsystem, systemantibody, antibodycovalent, covalentsec, secbrief, briefconjugates, conjugatescysteine, cysteinelysine
Multi-Attribute Methods for Biopharmaceutical Analysis
2022|Waters|Příručky
[ APPLICATION NOTEBOOK ] Multi-Attribute Methods for Biopharmaceutical Analysis Application Notes [ APPLICATION NOTEBOOK ] Introduction The adoption of LC-MS-based multi-attribute method (MAM) analysis for routine monitoring of biotherapeutic variation has progressed greatly over the last five years. The ability…
Klíčová slova
notebook, notebookattribute, attributebiopharmaceutical, biopharmaceuticalreturn, returnmulti, multimam, mamapplication, applicationcontents, contentspeptide, peptideattributes, attributesmethods, methodsacquity, acquitymab, mabbioaccord, bioaccordmonitoring