Highly Sensitive and Robust UPLC-MS/MS Quantification of Nitrosamine Impurities in Sartan and Ranitidine Drug Substances
Aplikace | 2020 | WatersInstrumentace
LC/MS, LC/MS/MS, LC/QQQ
ZaměřeníFarmaceutická analýza
VýrobceWaters
Klíčová slovanitrosamine, ranitidine, ndma, nmba, neipa, ndipa, impurities, ndba, ndea, drug, quantification, blank, six, nitrosamines, recalls, uplc, brief, xevo, sensitive, substances, acquity, careprofessionals, technology, alerting, gti, sartans, sartan, plus, daughter, voluntary, irbesartan, medications, retentivity, losartan, mutagenic, mrm, initial, valsartan, robust, class, waters, hss, curve, arb, statement, weighting, nitroso, highly, carcinogenic, patients
Podobná PDF
[ APPLICATION NOTE ] High Sensitivity Quantitation of Nitrosamine Genotoxic Impurities: LC-MS Analysis of Ranitidine Drug Product using the Waters ACQUITY UPLC I-Class/Xevo TQ-XS Tandem Quadrupole Mass Spectrometer Mary Trudeau Lame and Lindsay Hatch Waters Corporation, Milford, MA, USA APPLICATION…
Klíčová slova
ndma, ndmaranitidine, ranitidinenitrosamine, nitrosaminedrug, drugnmba, nmbablank, blankndba, ndbandea, ndeandipa, ndipaproduct, productarea, areaxevo, xevoneipa, neipauplc, uplcimpurities
Highly Sensitive and Robust UPLC-MS/MS Quantification of Nitrosamine Impurities in Sartan and Ranitidine Drug Substances
2020|Waters|Postery
Highly Sensitive and Robust UPLC-MS/MS Quantification of Nitrosamine Impurities in Sartan and Ranitidine Drug Substances Mary Trudeau Lame , Lindsay Hatch, Dave Higton, Paul Rainville, and Gordon Fujimoto Waters Corporation, Milford, MA, USA 2. UPLC Chromatographic Separation of Nitrosamine Impurities…
Klíčová slova
blank, blankranitidine, ranitidinendma, ndmadrug, drugndea, ndeamilford, milfordgti, gtisartan, sartanneipa, neipandipa, ndipandba, ndbanitrosamine, nitrosamineimpurities, impuritieslorsartan, lorsartanformulation
Reliable HPLC/UV Quantification of Nitrosamine Impurities in Valsartan and Ranitidine Drug Substances
2019|Waters|Aplikace
[ TECHNOLOGY BRIEF ] Reliable HPLC/UV Quantification of Nitrosamine Impurities in Valsartan and Ranitidine Drug Substances Margaret Maziarz and Paul Rainville Waters Corporation, Milford, MA, USA The ACQUITY Arc System with PDA Detector, integrated with an ACQUITY QDa Mass Detector…
Klíčová slova
nitrosamine, nitrosaminevalsartan, valsartanqda, qdaranitidine, ranitidinemin, minloq, loqimpurities, impuritiesndma, ndmaacquity, acquitynmba, nmbabrief, briefneipa, neipandipa, ndipadrug, drugreliable
Development of a Sensitive High Resolution Mass Spectrometry Method for Quantitation of N-Nitrosamines using Tof MRM on the Xevo G2-XS QTof
2020|Waters|Aplikace
Application Note Development of a Sensitive High Resolution Mass Spectrometry Method for Quantitation of N-Nitrosamines using Tof MRM on the Xevo G2-XS QTof Lauren Mullin, Margaret Maziarz, Mary E. Lame, Nathan Anderson Waters Corporation This is an Application Brief and…
Klíčová slova
nitrosamines, nitrosaminessartan, sartannitrosamine, nitrosaminetof, tofunifi, unifiinformatics, informaticsmrm, mrmclass, classhrms, hrmsgastroesophageal, gastroesophagealgxp, gxpstomach, stomachcarcinogenicity, carcinogenicitypusher, pusherplatform
