Charge Heterogeneity Analysis of Intact Infliximab Using CESI-MS and Neutral OptiMS Cartridge
Aplikace | 2019 | SCIEXInstrumentace
LC/TOF, LC/HRMS, LC/MS, LC/MS/MS, Kapilární elektroforéza
ZaměřeníKlinická analýza
VýrobceSCIEX
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Subunit charge variant characterization in the native state
2019|SCIEX|Aplikace
Subunit charge variant characterization in the native state Fang Wang1 Zoe Zhang2, 1SCIEX Brea, CA (USA) 2 SCIEX Redwood City, CA (USA), Monoclonal antibody (mAb) therapeutics often contain charge variants that arise from a wide array of post-translational modifications (PTM),…
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Monoclonal Antibody Charge Variants Identification by Fully Automated Capillary Isoelectric Focusing – Mass Spectrometry
2019|Agilent Technologies|Aplikace
Application Note Pharma & Biopharma Monoclonal Antibody Charge Variants Identification by Fully Automated Capillary Isoelectric Focusing – Mass Spectrometry Authors Tony Wang, James Xia, and Rena Wang CMP Scientific Corp, Brooklyn, NY, USA Jens Meixner Agilent Technologies, Inc. Waldbronn, Germany…
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Native State Charge Variant Analysis of Commercialized Monoclonal Antibodies in Minutes
2019|SCIEX|Aplikace
Native State Charge Variant Analysis of Commercialized Monoclonal Antibodies in Minutes CZE Rapid Charge Variant Analysis Kit Peter Holper, SCIEX Redwood City, CA Introduction A As biopharmaceutical companies face increasing pressure to decrease the overall drug development timeline, analytical researchers…
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Online IEX-MS of mAb Charge Variants Using a BioResolve SCX mAb Column, IonHance CX-MS pH Concentrates, and BioAccord System
2019|Waters|Aplikace
[ APPLICATION NOTE ] Online IEX-MS of mAb Charge Variants Using a BioResolve SCX mAb Column, IonHance CX-MS pH Concentrates, and BioAccord System Samantha Ippoliti, Andrew Schmudlach, Matthew A. Lauber, and Ying Qing Yu Waters Corporation, Milford, MA, USA APPLICATION…
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