Size-Exclusion Chromatography Method for Poly(A) Tail Analysis of mRNA
Aplikace | 2023 | WatersInstrumentace
GPC/SEC
ZaměřeníFarmaceutická analýza
VýrobceWaters
Klíčová slovatail, poly, mrna, exclusion, size, method, chromatography, analysis, sec, qsm, ftn, premier, gilar, uplc, acquity, length, martin, oligo, simple, adenosine, predominantly, heterogeneity, careers, privacy, oligonucleotide, cookie, cookies, oligonucleotides, preferences, describe, investigation, featured, note, minimal, longer, conditions, determining, terms, trademarks, sequence, application, filter, significantly, robust, suitable, waters, comparison, curve, testing, present
Podobná PDF
Ion-Pair Reversed-Phase Liquid Chromatography Method for Analysis of mRNA Poly(A) Tail Heterogeneity
2023|Waters|Aplikace
Application Note Ion-Pair Reversed-Phase Liquid Chromatography Method for Analysis of mRNA Poly(A) Tail Heterogeneity Martin Gilar, Maissa M. Gaye Waters Corporation Abstract Messenger RNA (mRNA) biopolymers are new therapeutic modalities. Development of effective mRNA vaccines against SARS-CoV-2 virus accelerated the…
Klíčová slova
tail, tailmrna, mrnapoly, polyheterogeneity, heterogeneitypair, pairreversed, reversedphase, phaseliquid, liquidion, ionmethod, methodchromatography, chromatographyanalysis, analysisssystem, ssystempremier, premierdiisopropylethylamine
Characterizing LNP mRNA
2024|Waters|Příručky
CONSUMABLES GUIDE BOOK Characterizing LNP mRNA LC tools for purity, identity, integrity and concentration determining measurements A Changing Industry mRNA based medicine helped address the COVID-19 pandemic. The viability of using an mRNA construct as a human drug substance has…
Klíčová slova
mrna, mrnalipid, lipidlnp, lnprplc, rplcvanguard, vanguardanion, anionbook, bookaex, aexcolumn, columndiameter, diameterfit, fitconsumables, consumablesguide, guideoligo, oligocsh
Rapid Analysis of Synthetic mRNA Cap Structure Using Ion-Pairing RPLC with the BioAccord LC-MS System
2021|Waters|Aplikace
Application Note Rapid Analysis of Synthetic mRNA Cap Structure Using Ion-Pairing RPLC with the BioAccord LC-MS System Jennifer M. Nguyen, Siu-Hong Chan, Bijoyita Roy, Martin Gilar, Brett Robb, Weibin Chen, Matthew A. Lauber Waters Corporation, New England Biolabs Inc. Abstract…
Klíčová slova
mrna, mrnabioaccord, bioaccordpremier, premiersurfaces, surfacesadsorb, adsorbmaxpeak, maxpeakacquity, acquitydiisopropylethylamine, diisopropylethylaminedipea, dipeaconfers, confersalkylamines, alkylamineshigh, highmodality, modalityrecipient, recipientelicit
Improving Chromatographic Separations Of Biopharmaceuticals With MaxPeak High Performance Surfaces (HPS) Technology
2023|Waters|Brožury a specifikace
Improving Chromatographic Separations Of Biopharmaceuticals With MaxPeak High Performance Surfaces (HPS) Technology Analytical Solutions Using MaxPeak High Performance Surfaces (HPS) Technology for Biopharmaceutical Therapeutics Biopharmaceutical therapeutics have consistently been the fastest growing segment within the pharmaceutical space and require advances…
Klíčová slova
premier, premieracquity, acquityglycan, glycanmaxpeak, maxpeaknucleotide, nucleotideculture, culturehps, hpspeptide, peptideintact, intactsystem, systembioaccord, bioaccordprotein, proteincolumn, columnread, readglycans