Shimadzu i-Series Specifications

C196-E099

High Performance Liquid Chromatograph

i-Series

Specifications

i-Series Specifications

Other Options

P/N

Description

Part Name

S228-56298-41

S228-55518-41

S228-55517-41

S228-55519-41

This kit is used to reinforce how the reservoir tray is attached.

This board is used to install additional connectors for optical link cables.
It is used to install fluorescence detector RF-20A series and other detectors.

This camera is installed inside autosamplers.
It allows you to monitor the needle action via the computer screen.

This is an analog-digital converter board. It is used to input the detector signal
as an analog signal, such as when a non-Shimadzu detector is connected.

Earthquake Reinforcement Kit

Optional Optical Board

Camera ASSY for Autosampler

Optional AD Board

S228-26004-44

S228-26004-43

This kit includes FCV-14AH for up to six columns switching and other parts.

This kit includes FCV-14AH for up to six columns switching, FCV-11AL for solvent delivery of seven 
mobile phases and other parts.

Smart Automation Kit 
(4-mobile phase)

S228-38583-42

This is a set of five one-liter reservoir bottles for holding mobile phases.

1 L Mobile Phase Bottles 
(set of 5)

S228-56245-41

This kit contains a top plate and reservoir tray for installing an additional detector.

Optional Detector Attachment 
Kit

Smart Automation Kit 
(7-mobile phase)

Touch Panel Protecting Sheet
Upgrade Kit UV
Upgrade Kit PDA

Protecting sheet for touch panel.

Kit for upgrade from LC-2050 (UV model with sample cooler) to LC-2060.

Kit for upgrade from LC-2050 (PDA model) to LC-2060.

S228-59212-41

S228-58993-41

S228-58993-42

•  Automated support functions utilizing digital technologies, such as M2M, IoT, and 

Artificial Intelligence (AI), that enable higher productivity and maximum reliability.

•  Allows a system to monitor and diagnose itself, handle any issues during data acquisition 

without user input, and automatically behave as if it were operated by an expert.

•  Supports the acquisition of high quality, reproducible data regardless of an operator's skill 

level for both routine and demanding applications.

Analytical Intelligence logo, LabSolutions and LCsolution are trademarks of Shimadzu Corporation.
Hastelloy is a registered trademark of Haynes International, Inc.

For Research Use Only. Not for use in diagnostic procedures.

This publication may contain references to products that are not available in your country. Please contact us to check the availability of 

these products in your country.

Company names, products/service names and logos used in this publication are trademarks and trade names of Shimadzu Corporation, 

its subsidiaries or its affiliates, whether or not they are used with trademark symbol “TM” or “®”.

Third-party trademarks and trade names may be used in this publication to refer to either the entities or their products/services, whether 

or not they are used with trademark symbol “TM” or “®”.

Shimadzu disclaims any proprietary interest in trademarks and trade names other than its own.

Shimadzu does not assume any responsibility or liability for any damage, whether direct or indirect, relating to the use of this publication.

www.shimadzu.com/an/

© Shimadzu Corporation, 2020

First Edition: November 2020 3655-10021-PDFNS

Use of Multiple Detectors Expands 
Application Range

Excellent Baseline Stability Unaffected 
by Circumstances

Supports High-Speed Multi-Analyte Processing

Autosampler Enhances Data Reliability

Auto Shutdown Function
Reduces Power 
Consumption

Maximum Reliability and Stability 
— Fundamental functions assure analysis results —

Open Access Sample Placement

System Monitoring via Smart Devices

Window on a Smartphone

In addition to the UV-visible (UV/VIS) absorbance detector or 
photodiode array (PDA) detector included as standard, a fluorescence 
detector or differential refractive index detector can be added.

Large-Capacity Column 
Oven Supports Up to 90°C

The Forced-air circulation method 
enhances column temperature 
stability. Maximum operating 
temperature of 90°C allows 
high-temperature analyses such as 
sugar analysis. Moreover, three 300 
mm long columns or six 100 mm long 
columns can be accommodated.

Quaternary Solvent
Delivery Unit

A 10 μL micro plunger ensures 
accurate quaternary gradient 
delivery. Optional reservoir switching 
valve further extends the solvent 
selection to seven so that the solvent 
for the flow path rinsing can be set.

The UV/VIS detector and the PDA detector employ dual-temperature 
control (TC-Optics and flow cell) and provide measurements with a 
stable baseline hardly affected by room temperature fluctuation.

Excellent reproducibility for injection volumes less than 1 μL, 
wide linearity range and ultra-low carryover (<0.0025%) improve 
the reliability of data, especially for analyses of precious 
biological samples and direct analyses of concentrated samples.

Compact Footprint

The i-Series brings together all the functions required for LC analysis in an integrated form. With its space-saving design, 
which is only 410 mm wide, three units can be installed on a laboratory bench compared to only two comparable 
instruments from other companies. The instrument footprint does not change even if another detector is installed.

After analysis is complete, the auto 
shutdown function minimizes power 
consumption in standby mode and 
can reduce power consumption by at 
least 95% compared to normal 
standby mode.

A 14-second injection cycle maximizes the number of samples 
that can be processed.

Moreover, a total of 1536 samples can be accommodated in 

right and left sample racks.

A direct access mechanism on sample racks allows the 
user to place the sample on racks that are not 
involved in sample injection even during analysis.

Furthermore, racks can be shared by multiple 

analysts, without interrupting the analysis of samples 
placed by others. Overall, this function enhances 
work efficiency.

System status and chromatograms can be viewed 
remotely from smart devices and home computers. 
Situations can be checked without needing to visit 
the laboratory.

Displays Chromatogram
in Real Time

Refined Usability

Control panel with a color LCD touch
panel allows anyone to operate the
instrument, regardless of experience 
level. Easily and reliably perform 
routine maintenance following 
on-screen instructions.

The chromatogram real-time monitor 
allows the user to immediately 
confirm the success or failure of data, 
even in a computer-less laboratory 
environment.

Use of Multiple Detectors Expands 
Application Range

Excellent Baseline Stability Unaffected 
by Circumstances

Supports High-Speed Multi-Analyte Processing

Autosampler Enhances Data Reliability

Auto Shutdown Function
Reduces Power 
Consumption

Maximum Reliability and Stability 
— Fundamental functions assure analysis results —

Open Access Sample Placement

System Monitoring via Smart Devices

Window on a Smartphone

In addition to the UV-visible (UV/VIS) absorbance detector or 
photodiode array (PDA) detector included as standard, a fluorescence 
detector or differential refractive index detector can be added.

Large-Capacity Column 
Oven Supports Up to 90°C

The Forced-air circulation method 
enhances column temperature 
stability. Maximum operating 
temperature of 90°C allows 
high-temperature analyses such as 
sugar analysis. Moreover, three 300 
mm long columns or six 100 mm long 
columns can be accommodated.

Quaternary Solvent
Delivery Unit

A 10 μL micro plunger ensures 
accurate quaternary gradient 
delivery. Optional reservoir switching 
valve further extends the solvent 
selection to seven so that the solvent 
for the flow path rinsing can be set.

The UV/VIS detector and the PDA detector employ dual-temperature 
control (TC-Optics and flow cell) and provide measurements with a 
stable baseline hardly affected by room temperature fluctuation.

Excellent reproducibility for injection volumes less than 1 μL, 
wide linearity range and ultra-low carryover (<0.0025%) improve 
the reliability of data, especially for analyses of precious 
biological samples and direct analyses of concentrated samples.

Compact Footprint

The i-Series brings together all the functions required for LC analysis in an integrated form. With its space-saving design, 
which is only 410 mm wide, three units can be installed on a laboratory bench compared to only two comparable 
instruments from other companies. The instrument footprint does not change even if another detector is installed.

After analysis is complete, the auto 
shutdown function minimizes power 
consumption in standby mode and 
can reduce power consumption by at 
least 95% compared to normal 
standby mode.

A 14-second injection cycle maximizes the number of samples 
that can be processed.

Moreover, a total of 1536 samples can be accommodated in 

right and left sample racks.

A direct access mechanism on sample racks allows the 
user to place the sample on racks that are not 
involved in sample injection even during analysis.

Furthermore, racks can be shared by multiple 

analysts, without interrupting the analysis of samples 
placed by others. Overall, this function enhances 
work efficiency.

System status and chromatograms can be viewed 
remotely from smart devices and home computers. 
Situations can be checked without needing to visit 
the laboratory.

Displays Chromatogram
in Real Time

Refined Usability

Control panel with a color LCD touch
panel allows anyone to operate the
instrument, regardless of experience 
level. Easily and reliably perform 
routine maintenance following 
on-screen instructions.

The chromatogram real-time monitor 
allows the user to immediately 
confirm the success or failure of data, 
even in a computer-less laboratory 
environment.

4

5

Specifications

Flow rate accuracy

Flow rate precision
Configuration

Gradient / range of 
set concentrations

Gradient / 
concentration accuracy

Gradient / 
concentration precision

Maximum pressure

System Delay 
Volume

Cross-contamination

Injection cycle time
Samples for processing

Sample cooler

Containable column 
size

Not included

0 to 100%, in 0.1% steps

±0.5% (0.1 to 2 mL/min, 1 to 20 MPa, Specified condition)

±0.1% (1 mL/min,10 MPa, Specified condition)

Min. 14 sec (Specified condition)

336 (1 mL), 216 (1.5 mL), 112 (4 mL), 4 (MTP/DWP)

Heating and cooling 
method

Forced air circulation method

Temperature control 
range

Flow rate switching 
valve

Room temperature − 12 to 90°C, Setting range 4 to 90°C

Temperature control 
precision

Temperature stability

±0.1°C

±0.8°C (Specified condition)

0.0025% (Caffeine, Specified condition)

650 µL

(Option: 460 µL, 1100 µL)

4 to 45°C (Room temperature needs to be 30°C or lower and the humidity 70% or less

to go down to 4°C. Room temperature needs to be 15°C or higher to go up to 45°C.)

6 pieces at 10 cm max., 3 pieces at 10 to 30 cm

2 pieces at

10 to 30 cm

Not allowed

460 µL

(Option: 650 µL, 1100 µL)

505 μL

(Flow path 1)

765 μL

(Flow path 2)

Max. 1 pc

≤ ±1% or ≤ ±2 μL/min, below whichever is greater

(0.01 to 2 mL/min, Specified condition)

≤ ±2%

(2 to 5 mL/min, Specified condition)

≤ ±1% or ≤ ±2 μL/min, below whichever is greater

(0.01 to 2 mL/min,1 to 40 MPa, Specified condition)

≤ ±2% or ≤ ±2 μL/min, below whichever is greater

(0.01 to 3 mL/min, 40 to 60 MPa, Specified condition)

0.1 to 100 µL

(Option: 0.1 to 50 µL, 1 to 500 µL, 1 to 2,000 µL)

0.1 to 50 µL

(Option: 0.1 to 100 µL, 1 to 500 µL, 1 to 2,000 µL)

50 MPa (0.0001 to 5 mL/min)
22 MPa (5.0001 to 10 mL/min)

Injection volume 
reproducibility

RSD < 0.20% (5.0−2000 μL)
RSD < 0.25% (2.0−4.9 μL)
RSD < 0.5%  (1.0−1.9 μL)
RSD < 1.0%  (0.5−0.9 μL)

70 MPa (0.0001 to 3 mL/min) 
44 MPa (3.0001 to 5 mL/min)
22 MPa (5.0001 to 10 mL/min)

S228-65824-58 S228-65825-58

S228-65821-58 S228-65822-58 S228-65823-58

S228-65820-58

S228-65826-58

Five Lines: Mobile phase 4 + Rinse solution 1 (Volume 400 μL)

Parallel-type double plunger

≤ 0.1 MPa (1.0 mL/min,10 MPa, Water)

0.0001 to 10 mL/min

< 0.06 %RSD or < 0.02 minSD, below whichever is greater

Four-solvent low-pressure gradient

LC-2050C 3D

(PDA model)

LC-2050C LT

detector-less

model

LC-2060C 3D

MT

(PDA model)

LC-2060C

(UV model)

LC-2060C 3D

(PDA model)

Model

Degassing unit
Pumping method
Pulsation

Flow rate setting 
range

Total-volume sample injection

Injection method

±1% (50 μL, N = 10)

Injection volume 
accuracy

Injection volume 
setting range

> 0.9999

(1 to 100 μL, Specified condition)

> 0.9999

(1 to 50 μL, Standard Sample Loop, 

Specified condition),

> 0.9999

(1 to 100 μL, 100 μL Sample Loop (Option),

Specified condition)

Injection linearity

P/N

Pu

m

p

A

u

to

sa

m

pl

er

C

o

lumn

 O

ve

n

LC-2050

UV model

without sample

cooler

(

)

(

)

LC-2050C

(UV model)

LC-2050C 3D

(PDA model)

LC-2050C LT

detector-less

model

LC-2060C 3D

MT

(PDA model)

LC-2060C

(UV model)

LC-2060C 3D

(PDA model)

Model

LC-2050

UV model

without sample

cooler

(

)

(

)

LC-2050C

(UV model)

S228-65821-58

S228-65820-58

S228-65824-58

Option cell

Flow cell

U

V

 Det

ec

to

r

190 to 700 nm

8 nm

≤ ±1 nm

High-Speed: 8 μL (10 mm, TC),

Semi-micro: 2.5 μL (5mm, TC)

Conventional: 12 μL (10 mm, TC),

Semi-micro: 2.5 μL (5 mm, TC)

12 μL (10 mm, TC), 12 MPa

8 μL (10 mm, TC), 12 MPa

LC-2050

UV model

without sample cooler

(

)

LC-2050C

(UV model)

LC-2060C

(UV model)

Model

Wavelength range
Spectral bandwidth
Wavelength accuracy

Up to 2.5 AU (5%)

Up to 100 Hz

Deuterium (D2) lamp

Linearity
Sampling rate
Light source

≤ ±2.5 × 10−6 AU, (250 nm, Specified condition)

≤ 100 × 10−6 AU/h (250 nm, Specified condition)

Noise level
Drift

P/N

Option cell

Flow cell

PD

A

 Det

ec

to

r

190 to 800 nm

1.4 nm (Specified condition)

1.2 nm, 8 nm

0.6 nm/pixel

1024

≤ ±1 nm

≤ ±3 × 10−6 AU (250 nm, reference: 350 nm, Specified condition)

≤ 500 × 10−6 AU/h (250 nm, reference: 350 nm, Specified condition)

Up to 2 AU (5%)

Up to 100 Hz

Deuterium (D2) lamp (Standard), tungsten (W) lamp (option)

High-Speed: 8 μL (10 mm, TC),

Semi-micro: 2.5 μL (5 mm, TC)

Conventional: 10 μL (10 mm, TC),

Semi-micro: 2.5 μL (5 mm, TC)

10 μL (10mm, TC), 12 MPa

8 μL (10 mm, TC), 12 MPa

S228-65822-58

LC-2050C 3D

(PDA model)

S228-65826-58

LC-2060C 3D MT

(PDA model)

S228-65825-58

LC-2060C 3D

(PDA model)

Model

Wavelength range
Spectral resolution
Slit width
Device resolution

P/N

Wavelength accuracy
Noise level
Drift
Linearity
Sampling rate
Light source

Number of 
photodiode array 
elements

≤ ±0.1 nm

Wavelength 
reproducibility

Enable (Any 2 wavelengths of 190 to 370 nm or 371 to 700 nm)

Simultaneous 
monitoring of 
2 wavelengths

S228-65824-58 S228-65825-58

S228-65821-58 S228-65822-58 S228-65823-58

S228-65820-58

S228-65826-58

W410×H605×D500 mm (Not including reservoir tray height)

Dimensions
Weight
Available pH range

P/N

Materials for parts
in contact with 
liquids

Workstation

Stainless steel (SUS316L, SUS316), FEP, PEEK, PTFE,

perfluoroelastomer, ruby, sapphire,

Hastelloy C, UHMWPE, ceramic, PFA, quartz, PPS

Stainless steel (SUS316L, SUS316), FEP, PEEK, PTFE,

perfluoroelastomer, ruby, sapphire,

Hastelloy® C, GFP, ceramic, PFA, quartz, PPS

1 to 13

LabSolutions™ LC/GC Ver.5.103 or later, LabSolutions DB/CS Ver.6.103 or later (Incompatible with LCsolution™)

58 kg

63 kg

64 kg

63 kg

53 kg

Mi

sc

el

lan

eo

u

s

4

5

Specifications

Flow rate accuracy

Flow rate precision
Configuration

Gradient / range of 
set concentrations

Gradient / 
concentration accuracy

Gradient / 
concentration precision

Maximum pressure

System Delay 
Volume

Cross-contamination

Injection cycle time
Samples for processing

Sample cooler

Containable column 
size

Not included

0 to 100%, in 0.1% steps

±0.5% (0.1 to 2 mL/min, 1 to 20 MPa, Specified condition)

±0.1% (1 mL/min,10 MPa, Specified condition)

Min. 14 sec (Specified condition)

336 (1 mL), 216 (1.5 mL), 112 (4 mL), 4 (MTP/DWP)

Heating and cooling 
method

Forced air circulation method

Temperature control 
range

Flow rate switching 
valve

Room temperature − 12 to 90°C, Setting range 4 to 90°C

Temperature control 
precision

Temperature stability

±0.1°C

±0.8°C (Specified condition)

0.0025% (Caffeine, Specified condition)

650 µL

(Option: 460 µL, 1100 µL)

4 to 45°C (Room temperature needs to be 30°C or lower and the humidity 70% or less

to go down to 4°C. Room temperature needs to be 15°C or higher to go up to 45°C.)

6 pieces at 10 cm max., 3 pieces at 10 to 30 cm

2 pieces at

10 to 30 cm

Not allowed

460 µL

(Option: 650 µL, 1100 µL)

505 μL

(Flow path 1)

765 μL

(Flow path 2)

Max. 1 pc

≤ ±1% or ≤ ±2 μL/min, below whichever is greater

(0.01 to 2 mL/min, Specified condition)

≤ ±2%

(2 to 5 mL/min, Specified condition)

≤ ±1% or ≤ ±2 μL/min, below whichever is greater

(0.01 to 2 mL/min,1 to 40 MPa, Specified condition)

≤ ±2% or ≤ ±2 μL/min, below whichever is greater

(0.01 to 3 mL/min, 40 to 60 MPa, Specified condition)

0.1 to 100 µL

(Option: 0.1 to 50 µL, 1 to 500 µL, 1 to 2,000 µL)

0.1 to 50 µL

(Option: 0.1 to 100 µL, 1 to 500 µL, 1 to 2,000 µL)

50 MPa (0.0001 to 5 mL/min)
22 MPa (5.0001 to 10 mL/min)

Injection volume 
reproducibility

RSD < 0.20% (5.0−2000 μL)
RSD < 0.25% (2.0−4.9 μL)
RSD < 0.5%  (1.0−1.9 μL)
RSD < 1.0%  (0.5−0.9 μL)

70 MPa (0.0001 to 3 mL/min) 
44 MPa (3.0001 to 5 mL/min)
22 MPa (5.0001 to 10 mL/min)

S228-65824-58 S228-65825-58

S228-65821-58 S228-65822-58 S228-65823-58

S228-65820-58

S228-65826-58

Five Lines: Mobile phase 4 + Rinse solution 1 (Volume 400 μL)

Parallel-type double plunger

≤ 0.1 MPa (1.0 mL/min,10 MPa, Water)

0.0001 to 10 mL/min

< 0.06 %RSD or < 0.02 minSD, below whichever is greater

Four-solvent low-pressure gradient

LC-2050C 3D

(PDA model)

LC-2050C LT

detector-less

model

LC-2060C 3D

MT

(PDA model)

LC-2060C

(UV model)

LC-2060C 3D

(PDA model)

Model

Degassing unit
Pumping method
Pulsation

Flow rate setting 
range

Total-volume sample injection

Injection method

±1% (50 μL, N = 10)

Injection volume 
accuracy

Injection volume 
setting range

> 0.9999

(1 to 100 μL, Specified condition)

> 0.9999

(1 to 50 μL, Standard Sample Loop, 

Specified condition),

> 0.9999

(1 to 100 μL, 100 μL Sample Loop (Option),

Specified condition)

Injection linearity

P/N

Pu

m

p

A

u

to

sa

m

pl

er

C

o

lumn

 O

ve

n

LC-2050

UV model

without sample

cooler

(

)

(

)

LC-2050C

(UV model)

LC-2050C 3D

(PDA model)

LC-2050C LT

detector-less

model

LC-2060C 3D

MT

(PDA model)

LC-2060C

(UV model)

LC-2060C 3D

(PDA model)

Model

LC-2050

UV model

without sample

cooler

(

)

(

)

LC-2050C

(UV model)

S228-65821-58

S228-65820-58

S228-65824-58

Option cell

Flow cell

U

V

 Det

ec

to

r

190 to 700 nm

8 nm

≤ ±1 nm

High-Speed: 8 μL (10 mm, TC),

Semi-micro: 2.5 μL (5mm, TC)

Conventional: 12 μL (10 mm, TC),

Semi-micro: 2.5 μL (5 mm, TC)

12 μL (10 mm, TC), 12 MPa

8 μL (10 mm, TC), 12 MPa

LC-2050

UV model

without sample cooler

(

)

LC-2050C

(UV model)

LC-2060C

(UV model)

Model

Wavelength range
Spectral bandwidth
Wavelength accuracy

Up to 2.5 AU (5%)

Up to 100 Hz

Deuterium (D2) lamp

Linearity
Sampling rate
Light source

≤ ±2.5 × 10−6 AU, (250 nm, Specified condition)

≤ 100 × 10−6 AU/h (250 nm, Specified condition)

Noise level
Drift

P/N

Option cell

Flow cell

PD

A

 Det

ec

to

r

190 to 800 nm

1.4 nm (Specified condition)

1.2 nm, 8 nm

0.6 nm/pixel

1024

≤ ±1 nm

≤ ±3 × 10−6 AU (250 nm, reference: 350 nm, Specified condition)

≤ 500 × 10−6 AU/h (250 nm, reference: 350 nm, Specified condition)

Up to 2 AU (5%)

Up to 100 Hz

Deuterium (D2) lamp (Standard), tungsten (W) lamp (option)

High-Speed: 8 μL (10 mm, TC),

Semi-micro: 2.5 μL (5 mm, TC)

Conventional: 10 μL (10 mm, TC),

Semi-micro: 2.5 μL (5 mm, TC)

10 μL (10mm, TC), 12 MPa

8 μL (10 mm, TC), 12 MPa

S228-65822-58

LC-2050C 3D

(PDA model)

S228-65826-58

LC-2060C 3D MT

(PDA model)

S228-65825-58

LC-2060C 3D

(PDA model)

Model

Wavelength range
Spectral resolution
Slit width
Device resolution

P/N

Wavelength accuracy
Noise level
Drift
Linearity
Sampling rate
Light source

Number of 
photodiode array 
elements

≤ ±0.1 nm

Wavelength 
reproducibility

Enable (Any 2 wavelengths of 190 to 370 nm or 371 to 700 nm)

Simultaneous 
monitoring of 
2 wavelengths

S228-65824-58 S228-65825-58

S228-65821-58 S228-65822-58 S228-65823-58

S228-65820-58

S228-65826-58

W410×H605×D500 mm (Not including reservoir tray height)

Dimensions
Weight
Available pH range

P/N

Materials for parts
in contact with 
liquids

Workstation

Stainless steel (SUS316L, SUS316), FEP, PEEK, PTFE,

perfluoroelastomer, ruby, sapphire,

Hastelloy C, UHMWPE, ceramic, PFA, quartz, PPS

Stainless steel (SUS316L, SUS316), FEP, PEEK, PTFE,

perfluoroelastomer, ruby, sapphire,

Hastelloy® C, GFP, ceramic, PFA, quartz, PPS

1 to 13

LabSolutions™ LC/GC Ver.5.103 or later, LabSolutions DB/CS Ver.6.103 or later (Incompatible with LCsolution™)

58 kg

63 kg

64 kg

63 kg

53 kg

Mi

sc

el

lan

eo

u

s

6

7

Description

Part Name

P/N

Description

Part Name

P/N

Description

Part Name

P/N

Description

Part Name

P/N

Column Ovens

Description

Part Name

P/N

S228-65611-58

S228-65610-58

S228-56249-41

This is the mobile phase selection valve (3 flow lines).
An FCV-11AL connection kit is required to connect to an FCV-11AL unit.

This is the mobile phase selection valve (1 flow line).
An FCV-11AL connection kit is required to connect to an FCV-11AL unit.

This kit includes connector cables and other items necessary for connecting FCV-11AL 
and FCV-11ALS units.

This kit decreases the system volume to 650 μL.

This kit decreases the system volume to 460 μL.

Compatible Volume System Kit
Low Volume System Kit

This sample loop is used for injecting 50 μL volumes. (Standard configuration parts of LC-2060)

This sample loop is used for injecting 100 μL volumes. (Standard configuration parts of LC-2050)

This increases the injection volume to 500 μL.

This increases the injection volume to 2 mL.

Fitting for inlet to high-pressure capacity column

Fitting for inlet to high-pressure capacity column

Additional sample rack

Plate used to place 84 1 mL sample vials

Plate used to place 54 1.5 mL sample vials

FCV-11AL

FCV-11ALS

FCV-11AL Connection Kit

S228-57313-41

This parts set includes a mixer and tubing for using TFA or other UV-absorbing substance 
as a mobile phase.

780 μL Mixer Kit

S228-57313-42

S228-57796-42

S228-57796-43

This parts set includes a mixer and tubing for using TFA or other UV-absorbing substance 
as a mobile phase.

2 mL Mixer Kit

Solvent Delivery Units

Main Optional Accessories

S228-56074-44

S228-56074-42

S228-45405-41

S228-45405-42

S228-56867-41

S228-56867-43

S228-55735-41

S228-56197-41

S228-50830-92

Plate used to place 28 4 mL sample vials

S228-56197-42

50 μL Sample Loop  
100 μL Sample Loop
Optional 500 μL Sample Loop
Optional 2 mL Sample Loop
UHPLC Fitting (set of 1)
UHPLC Fitting (set of 10)
Sample Rack
Plate for 1 mL Sample Vials (set of 2)

Autosamplers

Column Clamp ASSY B5
Column Clamp ASSY B8

FCV Mounting Kit
CMD
CMD Cable

FCV-14AH

FCV-34AH

UV Detectors

PDA Detectors

S228-56808-41

S228-56167-41

S228-45621-41

S228-45605-46

This low-pressure flow-line selection valve is used to recycle mobile phase.

This cell is compatible with conventional analysis. (Standard configuration parts of LC-2050)

This cell is compatible with UHPLC analysis. (Standard configuration parts of LC-2060)

This cell is compatible with semi-micro analysis.

Recycle Valve
Flow Cell for UV Detectors
UHPLC Cell for UV Detectors
Semi-Micro Cell for UV Detectors

S228-57110-41

This assembly includes a tungsten lamp and its socket used for high-sensitivity analysis in the
long-wavelength region.

S228-42593-43

S228-45618-54

S228-45605-47

This cell is compatible with conventional analysis. (Standard configuration parts of LC-2050)

This cell is compatible with fast analysis. (Standard configuration parts of LC-2060)

This cell is compatible with semi-micro analysis.

Flow Cell for PDA Detectors
High-Speed Cell for PDA Detectors
Semi-Micro Cell for PDA Detectors

W Lamp ASSY for PDA Detectors

S228-15617-91

S228-15617-92

S228-65614-58

S228-45185-41

S228-55765-42

S228-37281-41

S228-39991

This set of clamps is for adding a column with an outside diameter between 6.4 and 9.5 mm.

This set of clamps is for adding a column with an outside diameter between 9.5 and 12.7 mm.

Automatic column switching valve with 6 positions and 7 ports which is usable at a pressure 
of 34.3 MPa max.

Automatic column switching valve with 6 positions and 7 ports which is usable at a pressure 
of 100 MPa max.

This parts kit is used to secure an FCV-14AH/ 34AH unit inside the column oven.

This column management device is used to record information about columns.

This cable is used to connect between the CMD and main units.

Plate for 1.5 mL Sample Vials 
(set of 2)

Plate used to place 54 1.5 mL sample vials

S228-61615-42

Metal plate for 1.5ml Sample 
Vials (set of 1)

Plate for 4 mL Sample Vials (set of 2)

Xenon lamp

0, 200 to 650 nm

Water Raman peak S/N 1200 min.

Low background S/N > 9000

W260 × D420 × H210 mm, 16 kg

Xenon lamp, low-pressure mercury lamp

(To check wavelength accuracy)

0, 200 to 750 nm

Water Raman peak S/N 2000 min.

Low background S/N > 12000

W260 × D420 × H210 mm, 18 kg

20 nm

±2 nm

±0.2 nm

12 μL, 2 MPa (approx. 20 kgf/cm2), SUS316L, PTFE (fluororesin), quartz

Four-wavelength detection, wavelength scanning

Liquid-leakage sensor

4 to 35°C

Light source

Wavelength range
Spectral bandwidth
Wavelength accuracy
Wavelength precision

S/N

Dimensions and weight

Cell capacity

Functions
Safety measures

RF-20A/RF-20AXS

ELSD-LT III

Optional Detector Specifications

RID-20A (S228-65306-58)

RF-20A (S228-65304-58)

ELSD-LT III (S228-65900-58)

RF-20AXS (S228-65305-58)

1 to 1.75 RIU

A mode: 0.01 to 500 μRIU

P and L modes: 1 to 5000 μRIU

No filtering, 0.05 to 10 sec, 11 steps

With a switch

Auto zero, auto optical zero, baseline shift functions

Reflective index 
measurement range

20 mL/min (150 mL/min with an option)

Maximum operating 
flow rate

30 to 60°C (0.01°C steps)

Temperature control 
of cell unit

SUS316L, quartz, PTFE, Al2O3, ETFE

Material in contact 
with liquid

0.4 MPa (4 kgf/cm2)

Maximum operating 
pressure

4 to 35°C

Operating 
temperature range

Range

Response
Polarity switching
Zero adjustment

RID-20A

Note: Hexafluoroisopropanol (HFIP) cannot be used as the mobile phase.

Siphon splitting

Semiconductor laser

Photodiode

W 250 × D 530 × H 330 mm, 15.5 kg

Nebulizing Method
Light Source
Detector

Air or nitrogen*

Nebulizer Gas

Dimensions and weight

* Supply gas at a pressure of about 350 kPa. An air compressor may also be used.
  A filter (P/N: S228-45528-92) is also available for filtering out moisture and other matter from the compressor.

Mobile Phase Flow Rate
(Standard Nebulizer)

0.2 to 2 mL/min

—

4 to 40°C, 1°C steps

—

(Room temperature − 10°C) to 40°C

Cell temperature 
control range
Cell temperature 
setting range

Operating 
temperature range

Room temperature to 100 °C

Temperature Setting 
Range

4 to 35 °C

Operating 
Temperature Range

20 to 85 %

Operating Humidity 
Range

≤ 2.5 nRIU

≤ 0.1 μRIU/h

Noise level
Drift

9 μL

Cell capacity

W260 × D420 × H140 mm, 12 kg

Dimensions and weight

6

7

Description

Part Name

P/N

Description

Part Name

P/N

Description

Part Name

P/N

Description

Part Name

P/N

Column Ovens

Description

Part Name

P/N

S228-65611-58

S228-65610-58

S228-56249-41

This is the mobile phase selection valve (3 flow lines).
An FCV-11AL connection kit is required to connect to an FCV-11AL unit.

This is the mobile phase selection valve (1 flow line).
An FCV-11AL connection kit is required to connect to an FCV-11AL unit.

This kit includes connector cables and other items necessary for connecting FCV-11AL 
and FCV-11ALS units.

This kit decreases the system volume to 650 μL.

This kit decreases the system volume to 460 μL.

Compatible Volume System Kit
Low Volume System Kit

This sample loop is used for injecting 50 μL volumes. (Standard configuration parts of LC-2060)

This sample loop is used for injecting 100 μL volumes. (Standard configuration parts of LC-2050)

This increases the injection volume to 500 μL.

This increases the injection volume to 2 mL.

Fitting for inlet to high-pressure capacity column

Fitting for inlet to high-pressure capacity column

Additional sample rack

Plate used to place 84 1 mL sample vials

Plate used to place 54 1.5 mL sample vials

FCV-11AL

FCV-11ALS

FCV-11AL Connection Kit

S228-57313-41

This parts set includes a mixer and tubing for using TFA or other UV-absorbing substance 
as a mobile phase.

780 μL Mixer Kit

S228-57313-42

S228-57796-42

S228-57796-43

This parts set includes a mixer and tubing for using TFA or other UV-absorbing substance 
as a mobile phase.

2 mL Mixer Kit

Solvent Delivery Units

Main Optional Accessories

S228-56074-44

S228-56074-42

S228-45405-41

S228-45405-42

S228-56867-41

S228-56867-43

S228-55735-41

S228-56197-41

S228-50830-92

Plate used to place 28 4 mL sample vials

S228-56197-42

50 μL Sample Loop  
100 μL Sample Loop
Optional 500 μL Sample Loop
Optional 2 mL Sample Loop
UHPLC Fitting (set of 1)
UHPLC Fitting (set of 10)
Sample Rack
Plate for 1 mL Sample Vials (set of 2)

Autosamplers

Column Clamp ASSY B5
Column Clamp ASSY B8

FCV Mounting Kit
CMD
CMD Cable

FCV-14AH

FCV-34AH

UV Detectors

PDA Detectors

S228-56808-41

S228-56167-41

S228-45621-41

S228-45605-46

This low-pressure flow-line selection valve is used to recycle mobile phase.

This cell is compatible with conventional analysis. (Standard configuration parts of LC-2050)

This cell is compatible with UHPLC analysis. (Standard configuration parts of LC-2060)

This cell is compatible with semi-micro analysis.

Recycle Valve
Flow Cell for UV Detectors
UHPLC Cell for UV Detectors
Semi-Micro Cell for UV Detectors

S228-57110-41

This assembly includes a tungsten lamp and its socket used for high-sensitivity analysis in the
long-wavelength region.

S228-42593-43

S228-45618-54

S228-45605-47

This cell is compatible with conventional analysis. (Standard configuration parts of LC-2050)

This cell is compatible with fast analysis. (Standard configuration parts of LC-2060)

This cell is compatible with semi-micro analysis.

Flow Cell for PDA Detectors
High-Speed Cell for PDA Detectors
Semi-Micro Cell for PDA Detectors

W Lamp ASSY for PDA Detectors

S228-15617-91

S228-15617-92

S228-65614-58

S228-45185-41

S228-55765-42

S228-37281-41

S228-39991

This set of clamps is for adding a column with an outside diameter between 6.4 and 9.5 mm.

This set of clamps is for adding a column with an outside diameter between 9.5 and 12.7 mm.

Automatic column switching valve with 6 positions and 7 ports which is usable at a pressure 
of 34.3 MPa max.

Automatic column switching valve with 6 positions and 7 ports which is usable at a pressure 
of 100 MPa max.

This parts kit is used to secure an FCV-14AH/ 34AH unit inside the column oven.

This column management device is used to record information about columns.

This cable is used to connect between the CMD and main units.

Plate for 1.5 mL Sample Vials 
(set of 2)

Plate used to place 54 1.5 mL sample vials

S228-61615-42

Metal plate for 1.5ml Sample 
Vials (set of 1)

Plate for 4 mL Sample Vials (set of 2)

Xenon lamp

0, 200 to 650 nm

Water Raman peak S/N 1200 min.

Low background S/N > 9000

W260 × D420 × H210 mm, 16 kg

Xenon lamp, low-pressure mercury lamp

(To check wavelength accuracy)

0, 200 to 750 nm

Water Raman peak S/N 2000 min.

Low background S/N > 12000

W260 × D420 × H210 mm, 18 kg

20 nm

±2 nm

±0.2 nm

12 μL, 2 MPa (approx. 20 kgf/cm2), SUS316L, PTFE (fluororesin), quartz

Four-wavelength detection, wavelength scanning

Liquid-leakage sensor

4 to 35°C

Light source

Wavelength range
Spectral bandwidth
Wavelength accuracy
Wavelength precision

S/N

Dimensions and weight

Cell capacity

Functions
Safety measures

RF-20A/RF-20AXS

ELSD-LT III

Optional Detector Specifications

RID-20A (S228-65306-58)

RF-20A (S228-65304-58)

ELSD-LT III (S228-65900-58)

RF-20AXS (S228-65305-58)

1 to 1.75 RIU

A mode: 0.01 to 500 μRIU

P and L modes: 1 to 5000 μRIU

No filtering, 0.05 to 10 sec, 11 steps

With a switch

Auto zero, auto optical zero, baseline shift functions

Reflective index 
measurement range

20 mL/min (150 mL/min with an option)

Maximum operating 
flow rate

30 to 60°C (0.01°C steps)

Temperature control 
of cell unit

SUS316L, quartz, PTFE, Al2O3, ETFE

Material in contact 
with liquid

0.4 MPa (4 kgf/cm2)

Maximum operating 
pressure

4 to 35°C

Operating 
temperature range

Range

Response
Polarity switching
Zero adjustment

RID-20A

Note: Hexafluoroisopropanol (HFIP) cannot be used as the mobile phase.

Siphon splitting

Semiconductor laser

Photodiode

W 250 × D 530 × H 330 mm, 15.5 kg

Nebulizing Method
Light Source
Detector

Air or nitrogen*

Nebulizer Gas

Dimensions and weight

* Supply gas at a pressure of about 350 kPa. An air compressor may also be used.
  A filter (P/N: S228-45528-92) is also available for filtering out moisture and other matter from the compressor.

Mobile Phase Flow Rate
(Standard Nebulizer)

0.2 to 2 mL/min

—

4 to 40°C, 1°C steps

—

(Room temperature − 10°C) to 40°C

Cell temperature 
control range
Cell temperature 
setting range

Operating 
temperature range

Room temperature to 100 °C

Temperature Setting 
Range

4 to 35 °C

Operating 
Temperature Range

20 to 85 %

Operating Humidity 
Range

≤ 2.5 nRIU

≤ 0.1 μRIU/h

Noise level
Drift

9 μL

Cell capacity

W260 × D420 × H140 mm, 12 kg

Dimensions and weight

C196-E099

High Performance Liquid Chromatograph

i-Series

Specifications

i-Series Specifications

Other Options

P/N

Description

Part Name

S228-56298-41

S228-55518-41

S228-55517-41

S228-55519-41

This kit is used to reinforce how the reservoir tray is attached.

This board is used to install additional connectors for optical link cables.
It is used to install fluorescence detector RF-20A series and other detectors.

This camera is installed inside autosamplers.
It allows you to monitor the needle action via the computer screen.

This is an analog-digital converter board. It is used to input the detector signal
as an analog signal, such as when a non-Shimadzu detector is connected.

Earthquake Reinforcement Kit

Optional Optical Board

Camera ASSY for Autosampler

Optional AD Board

S228-26004-44

S228-26004-43

This kit includes FCV-14AH for up to six columns switching and other parts.

This kit includes FCV-14AH for up to six columns switching, FCV-11AL for solvent delivery of seven 
mobile phases and other parts.

Smart Automation Kit 
(4-mobile phase)

S228-38583-42

This is a set of five one-liter reservoir bottles for holding mobile phases.

1 L Mobile Phase Bottles 
(set of 5)

S228-56245-41

This kit contains a top plate and reservoir tray for installing an additional detector.

Optional Detector Attachment 
Kit

Smart Automation Kit 
(7-mobile phase)

Touch Panel Protecting Sheet
Upgrade Kit UV
Upgrade Kit PDA

Protecting sheet for touch panel.

Kit for upgrade from LC-2050 (UV model with sample cooler) to LC-2060.

Kit for upgrade from LC-2050 (PDA model) to LC-2060.

S228-59212-41

S228-58993-41

S228-58993-42

•  Automated support functions utilizing digital technologies, such as M2M, IoT, and 

Artificial Intelligence (AI), that enable higher productivity and maximum reliability.

•  Allows a system to monitor and diagnose itself, handle any issues during data acquisition 

without user input, and automatically behave as if it were operated by an expert.

•  Supports the acquisition of high quality, reproducible data regardless of an operator's skill 

level for both routine and demanding applications.

Analytical Intelligence logo, LabSolutions and LCsolution are trademarks of Shimadzu Corporation.
Hastelloy is a registered trademark of Haynes International, Inc.

For Research Use Only. Not for use in diagnostic procedures.

This publication may contain references to products that are not available in your country. Please contact us to check the availability of 

these products in your country.

Company names, products/service names and logos used in this publication are trademarks and trade names of Shimadzu Corporation, 

its subsidiaries or its affiliates, whether or not they are used with trademark symbol “TM” or “®”.

Third-party trademarks and trade names may be used in this publication to refer to either the entities or their products/services, whether 

or not they are used with trademark symbol “TM” or “®”.

Shimadzu disclaims any proprietary interest in trademarks and trade names other than its own.

Shimadzu does not assume any responsibility or liability for any damage, whether direct or indirect, relating to the use of this publication.

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© Shimadzu Corporation, 2020

First Edition: November 2020 3655-10021-PDFNS