Analyzing Monoclonal Antibody (mAb) Fragments and Dimers Using Size Exclusion Chromatography (SEC)
Ostatní | 2021 | Agilent TechnologiesInstrumentace
Spotřební materiál, LC kolony, GPC/SEC
ZaměřeníFarmaceutická analýza
VýrobceAgilent Technologies
Klíčová slovamylist, sec, advancebio, column, infinitylab, dimers, ideal, quick, fragments, aggregate, aggregates, agilent, supplies, separation, columns, storage, maximum, turn, fitting, mab, uridine, resolution, secondary, size, pores, factors, lined, weeks, rates, infinity, store, solvent, require, improve, protein, sample, peek, weight, pore, flow, minimizing, molecular, filtration, strength, fittings, additives, lower, pressuring, exclusion, bio
Podobná PDF
Analyzing Monoclonal Antibody (mAbs) and mAb-Derived Therapeutics Using Native SEC-MS
2021|Agilent Technologies|Aplikace
Consumables Workflow Ordering Guide Analyzing Monoclonal Antibody (mAbs) and mAb-Derived Therapeutics Using Native SEC-MS The quantitation of aggregates is of particular concern for protein-based-therapies given their potential effect on efficacy and immunogenicity. Size exclusion chromatography (SEC) combined with UV detection…
Klíčová slova
mylist, mylistsec, seclined, linedpeek, peekcolumn, columnadvancebio, advancebiointerfere, interfereinfinitylab, infinitylabrates, ratescovalent, covalentmab, mabrecommended, recommendedadducts, adductsprotein, proteinstorage
Improving the Quality of Antibody Drug Conjugates by Orthogonal Analytical Methods
2024|Agilent Technologies|Příručky
Consumables Workflow Ordering Guide Improving the Quality of Antibody Drug Conjugates by Orthogonal Analytical Methods Antibody Drug Conjugates Antibody-drug conjugates (ADCs) represent a new generation of targeted biotherapeutics that make up a rapidly growing segment of the drug discovery pipeline.…
Klíčová slova
mylist, mylistcysteine, cysteinedar, daradc, adcadcs, adcslysine, lysinelinker, linkercolumn, columnhic, hicauristatin, auristatinvedotin, vedotinantibody, antibodymmae, mmaeintact, intactinfinitylab
Aggregate Analysis of Adeno-Associated Viruses and Virus-Like Particles in Biopharma by Liquid Chromatography
2023|Agilent Technologies|Příručky
Consumables Workflow Ordering Guide Aggregate Analysis of Adeno-Associated Viruses and Virus-Like Particles in Biopharma by Liquid Chromatography Adeno-associated viruses (AAVs) and virus-like particles (VLPs) are emerging biotherapeutic molecules with exciting potential in the vaccine, cell, and gene therapy spaces. AAVs…
Klíčová slova
pore, poresec, secviruses, virusesinfinitylab, infinitylabvirus, virussize, sizeaggregate, aggregatecolumn, columnthumb, thumbaavs, aavsglobular, globularadeno, adenothyroglobulin, thyroglobulinrule, rulepart
Helpful ‘Hints’ for Protein SEC Success
2021|Agilent Technologies|Prezentace
Helpful ‘Hints’ for Protein SEC Success Jean Lane Applications Engineer LC columns and consumables technical support May 27, 20201 Outline for Talk Getting started • SEC definition, common terminology, and why use it? • Considerations for selecting an SEC column…
Klíčová slova
hints, hintshelpful, helpfulsec, secsuccess, successprotein, proteinpore, poreadvancebio, advancebiosize, sizebuffer, bufferexclusion, exclusionmobile, mobilephase, phasecolumn, columndimer, dimervolume