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CCS-aware SpatialOMx® enables highly confident and automatic lipid annotations with regiospecific context

Aplikace | 2021 | BrukerInstrumentace
Iontová mobilita, MALDI, MS Imaging, LC/TOF, LC/HRMS, LC/MS, LC/MS/MS
Zaměření
Lipidomika
Výrobce
Bruker
Klíčová slova
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4D-Lipidomics™ workflow for increased throughput Lipid profiling from complex lipid extracts can be a challenging and time consuming task. The high complexity of samples and co-elution of isobaric or isomeric compounds complicate the confident annotation of lipids. The presented 4D-Lipidomics…
Klíčová slova
ccs, ccsannotation, annotationlipid, lipidannotations, annotationslipids, lipidstimstof, timstofaware, awarebased, basedcoverage, coveragevalues, valuescan, candeep, deepmobility, mobilityrule, ruleannotated
timsTOF MALDI Guided SpatialOMx Innovation with Integrity TIMS-MALDI MS MALDI Guided SpatialOMx The tumor microenvironment is a highly variable ecosystem, giving it an intrinsic temporal character. De-coding the cellular communication within the tumor microenvironment via label-free MALDI Imaging and x-omics…
Klíčová slova
maldi, malditimstof, timstofspatialomx, spatialomxflex, fleximaging, imagingbruker, brukerlaunches, launchesscils, scilstumor, tumorpasef, pasefmicroenvironment, microenvironmenttissue, tissueomics, omicslab, labtims
Product Overview Life Science Mass Spectrometry Innovation with Integrity Mass Spectrometry Empowering Science with Innovation and Integrity As one of the world’s leading analytical instrumentation companies, Bruker offers a broad spectrum of advanced solutions in all fields of research and…
Klíčová slova
maldi, malditof, tofbruker, brukerpasef, pasefrapiflex, rapiflexevoq, evoqspectrometry, spectrometryscimax, scimaxtimstof, timstofmass, massmrms, mrmsproteomics, proteomicsmetaboscape, metaboscapelrf, lrfseries
Novel MALDI Imaging solution empowered by a timsTOF fleX and dedicated bioinformatics pipeline for identification of lipids from tissue MALDI Imaging spectra can be used to investigate how compounds are localized across tissue samples. In this application note, we present…
Klíčová slova
scils, scilsimaging, imagingmaldi, malditimstof, timstofflex, flextissue, tissuemetaboscape, metaboscapeannotations, annotationslab, labannotation, annotationbruker, brukerdata, dataroi, roiannotated, annotatedmolecules
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LabRulez s.r.o. Všechna práva vyhrazena. Obsah dostupný pod licencí CC BY-SA 4.0 Uveďte původ-Zachovejte licenci.