Nové farmaceutické a biofarmaceutické aplikace Thermo Scientific

Přehled literatury s využitím Iontové chromatografie (5)

• HPAE-PAD method for determination of Hib capsular polysaccharide content (Aplikace | 2022)

• Determination of KDO from bacterial lipopolysaccharides (Aplikace | 2022)

• Determination of phosphite and phosphate in ibandronate sodium (Aplikace | 2022)

• Assay of guanidine in pharmaceutical formulations (Aplikace | 2022)

• HPLC: Assay of Tromethamine in Pharmaceutical Formulations (Postery | 2022)

Přehled literatury s využitím Kapalinové chromatografie (10)

• Simultaneous reversed-phase and anion-exchange method scouting with a dual system for mRNA impurity determination (Aplikace | 2022)

• Automated UHPLC method development for mebendazole and related impurities, from method scouting to robustness testing (Aplikace | 2022)

• HPLC: Automated HPLC method development and robustness tests for abacavir, lamivudine, dolutegravir and their related compounds in Triumeq drug produ (Postery | 2022)

• HPLC: Simultaneous reversed-phase and anion-exchange method scouting with a dual system for mRNA impurity determination (Postery | 2022)

• HPLC: Combining mass spectra, retention time modelling, and charged aerosol detection for unambiguous peak annotation and uniform-response quantitation in polysorbate profiling (Postery | 2022)

• HPLC: Automated UHPLC method development and robustness test for mebendazole and related impurities (Postery | 2022)

• HPLC: High-throughput analysis of oligonucleotides using a single quadrupole mass spectrometer for quality control (Postery | 2022)

• Simultaneous analysis of drug substances according to USP assay and impurity methods (Aplikace | 2022)

• Parallel analysis of drug product for assay and related substances determination (Aplikace | 2022)

• Assessing key attributes of adeno-associated viral proteins using HPLC-FLD-intact mass analysis (Aplikace | 2022)

Přehled literatury s využitím Hmotnostní spektrometrie s jednoduchým kvadrupólem (2)

• HPLC: Combining mass spectra, retention time modelling, and charged aerosol detection for unambiguous peak annotation and uniform-response quantitation in polysorbate profiling (Postery | 2022)

• HPLC: High-throughput analysis of oligonucleotides using a single quadrupole mass spectrometer for quality control (Postery | 2022)

Přehled literatury s využitím Hmotnostní spektrometrie s vysokým rozlišením Orbitrap (15)

• Thermo Scientific Direct Mass Technology mode (Brožury a specifikace | 2022)

• HPLC: QA/QC Analytical Methods for the Structural Analysis of Biotherapeutic Viruses (Postery | 2022)

• ASMS: Retention Time Based FAIMS Depletion of Protein Drugs in Peptide Mapping to Increase Coverage of Background Host Cell Proteins (Postery | 2022)

• ASMS: Characterization and quantification of lipid nanoparticle components and their degradants in vivo using an LC-HRAM MS platform (Postery | 2022)

• ASMS: Characterization of monoclonal antibodies and antibody drug conjugates using iCIEF-MS online coupling platform (Postery | 2022)

• ASMS: Characterization of mRNA vaccine 5’ and 3’ end products using BioPharma Finder 5.0 (Postery | 2022)

• ASMS: Accelerated Solvent Extraction & Ultra-High Performance Liquid Chromatography Coupled with High-Resolution Mass Spectrometry For Analysis of Additives in Polymers For Biomanufacturing Processes (Postery | 2022)

• ASMS: Streamlining workflow from characterization to monitoring of therapeutic oligonucleotides impurities across IPRP-LC-HRAM-MS platforms (Postery | 2022)

• The MAM 2.0 workflow enables seamless transition from research and development to quality control (Aplikace | 2022)

• Assessing key attributes of adeno-associated viral proteins using HPLC-FLD-intact mass analysis (Aplikace | 2022)

• Consistent results for peptide mapping and monitoring across three systems of the Vanquish UHPLC platform (Aplikace | 2022)

• mRNA direct sequence mapping using automated partial digestion with magnetic nuclease and LC-HRMS (Aplikace | 2022)

• Characterization of in vitro-transcribed (IVT) mRNA poly(A) tail by LC-HRAM-MS and BioPharma Finder 5.0 software (Aplikace | 2022)

• Characterization of mRNA 5’ capping products using an LC-HRAM-MS/MS analytical platform and Thermo Scientific BioPharma Finder software solution (Aplikace | 2022)

• A validated LC-HRAM-MS method for the rapid and confident determination of azido (AZBT) impurity in sartan drug products (Aplikace | 2022)

Pro více informací nás neváhejte kontaktovat na eliasova@pragolab.cz