<p><strong>Odborníci z Přírodovědecké fakulty Univerzity Palackého pomáhají restaurátorům s loni zahájenou obnovou sloupu Nejsvětější Trojice, který je zapsán na Seznamu světového dědictví UNESCO. Chemici, fyzici a geoinformatici na této dominantě historického centra města v uplynulých týdnech detailně prozkoumali její zlacené části, získaná data využijí restaurátoři při citlivé a odborně podložené rekonstrukci této památky.</strong></p><p>Obnovu sloupu Nejsvětější Trojice dostal na starost restaurátor René Tikal, na akci odborně dohlíží Národní památkový ústav. Přírodovědecká fakulta byla přizvána ke spolupráci, aby prostřednictvím svých expertíz a měření pomohla zajistit co nejpřesnější restaurování zlacených částí této významné památky. Do projektu se zapojili odborníci z kateder analytické chemie a geoinformatiky a také <strong>experti ze Společné laboratoře optiky, což je pracoviště Univerzity Palackého a Fyzikálního ústavu Akademie věd ČR</strong>. Vědci se zaměřili na měření lesku zlacených prvků barokního sloupu a posouzení jejich složení a aktuálního stavu. Na měření se podíleli Josef Kadlec, Karel Lemr, Jan Soubusta a Martin Zeman ze Společné laboratoře optiky, Petr Bednář a Lukáš Kučera z katedry analytické chemie a Stanislav Popelka s Michaelou Vojtěchovskou z katedry geoinformatiky.</p><blockquote><p>„<i><strong>Plánujeme srovnávací měření na in vitro vzorcích slitin s cílem určit, která z nich má nejpodobnější vlastnosti k původnímu materiálu a může být využita restaurátorem při obnově.</strong></i>“ Karel Lemr</p></blockquote><p>„<i>V optické části jsme provedli úvodní měření pomocí glosmetru, zařízení určeného ke kvantifikaci lesklosti povrchů. Získaná data, která objektivně číselně popisují rozdíly viditelné pouhým okem, budou propojena s výsledky kolegů z katedry analytické chemie. Následně plánujeme srovnávací měření na in vitro vzorcích slitin s cílem určit, která z nich má nejpodobnější vlastnosti k původnímu materiálu a může být využita restaurátorem při obnově,</i>“ uvedl <strong>Karel Lemr ze Společné laboratoře optiky</strong>.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/UPOL_Ludek_Perina_Odbornici_z_prirodovedecke_fakulty_pomahaji_s_obnovou_sloupu_Nejsvetejsi_Trojice_4_155b9e9358.jpg" alt="UPOL / Luděk Peřina: Odborníci z přírodovědecké fakulty pomáhají s obnovou sloupu Nejsvětější Trojice" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_UPOL_Ludek_Perina_Odbornici_z_prirodovedecke_fakulty_pomahaji_s_obnovou_sloupu_Nejsvetejsi_Trojice_4_155b9e9358.jpg 208w," sizes="100vw" width="471" height="353"></p><p>Katedra analytické chemie se zaměřila na analýzy složení materiálu, zejména s využitím rentgenové fluorescenční spektrometrie. Díky této technice lze zjistit zastoupení jednotlivých prvků v podpovrchových vrstvách i odhadnout tloušťku zlacení v různých místech. „<i>Výsledky měření ukázaly obsahy dominantních prvků, jako je měď, zlato a olovo, na základě kterých můžeme odvodit, jak silná je vrstva zlacení. Čím je tenčí, tím více mědi pod ní naměříme. Důležitým zjištěním je také přítomnost olova, která souvisí s historicky používanou technologií zlacení. Tehdy se proces prováděl při vysokých teplotách právě s využitím olova, které pomáhalo vrstvy spojit. V současnosti se tato metoda již nepoužívá, mimo jiné proto, že olovo je toxické,</i>“ podotkl <strong>Petr Bednář z katedry analytické chemie</strong>.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/UPOL_Ludek_Perina_Odbornici_z_prirodovedecke_fakulty_pomahaji_s_obnovou_sloupu_Nejsvetejsi_Trojice_3_c24e829d2b.jpg" alt="UPOL / Luděk Peřina: Odborníci z přírodovědecké fakulty pomáhají s obnovou sloupu Nejsvětější Trojice" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_UPOL_Ludek_Perina_Odbornici_z_prirodovedecke_fakulty_pomahaji_s_obnovou_sloupu_Nejsvetejsi_Trojice_3_c24e829d2b.jpg 208w," sizes="100vw" width="471" height="353"></p><p>Katedra geoinformatiky všechna pořízená data zpracovala a začlenila do interaktivního 3D modelu sloupu Nejsvětější Trojice. „<i>Ten slouží jako úložiště dat v podobě interaktivních vrstev, které lze snadno vyhledávat a vizualizovat. Pověření uživatelé tak mají přístup k jednotlivým měřením prostřednictvím přehledného zobrazení,</i>“ uvedl <strong>Stanislav Popelka z katedry geoinformatiky</strong>.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/UPOL_Ludek_Perina_Odbornici_z_prirodovedecke_fakulty_pomahaji_s_obnovou_sloupu_Nejsvetejsi_Trojice_2_ac568fa308.jpg" alt="UPOL / Luděk Peřina: Odborníci z přírodovědecké fakulty pomáhají s obnovou sloupu Nejsvětější Trojice" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_UPOL_Ludek_Perina_Odbornici_z_prirodovedecke_fakulty_pomahaji_s_obnovou_sloupu_Nejsvetejsi_Trojice_2_ac568fa308.jpg 208w," sizes="100vw" width="471" height="353"></p><p>Všechna měření proběhla za přítomnosti restaurátora Reného Tikala a zástupce Národního památkového ústavu Františka Chupíka. Odborníci z Přírodovědecké fakulty UP nyní s pracovníky Národního památkového ústavu a restaurátorem získaná data interpretují pro účely optimálního provedení restaurátorských zásahů.</p><p>Restaurátoři se do opravy 32 metrů vysokého sloupu Nejsvětější Trojice pustili loni na jaře a dokončit ji plánují v závěru příštího roku. Rekonstrukce bude stát zhruba 30 milionů korun. Radnici se na projekt podařilo získat dotaci, která pokryje většinu nákladů.</p>

Odborníci z přírodovědecké fakulty pomáhají s obnovou sloupu Nejsvětější Trojice

<p><strong>Explozivní látky představují skupinu environmentálních polutantů, které se do prostředí dostávají především v důsledku vojenských aktivit, výroby, skladování nebo likvidace munice. Jejich přítomnost v půdě a vodě je spojena s riziky pro ekosystémy i lidské zdraví. Některé sloučeniny, například hexogen (RDX) a 2,4-dinitrotoluen (2,4-DNT), jsou dokonce klasifikovány jako potenciální karcinogeny. Proto je monitoring, analytické stanovení a vypracování strategií účinného odstraňování výbušnin a jejich reziduí z životního prostředí zásadní pro účinnou minimalizaci souvisejících rizik.</strong></p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/ALS_Czech_Republic_Exploziva_5959ee2127.jpg" alt="ALS Czech Republic: Obrázek 1: Ilustrativní obrázek" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_ALS_Czech_Republic_Exploziva_5959ee2127.jpg 158w," sizes="100vw" width="702" height="694"></p><h4><strong>Výbušniny v životním prostředí</strong></h4><p><strong>V roce 2025 laboratoř ALS rozšířila své analytické portfolio o akreditované metody pro stanovení výbušnin a souvisejících sloučenin ve vodě a půdě. Tyto postupy vycházejí z mezinárodně uznávaných norem, jako jsou US EPA 8330B, EN ISO 22478 a ISO 11916-1.</strong></p><p>Návrh a zavádění efektivních postupů pro identifikaci a sanaci explozivních látek v environmentálních vzorcích, zejména ve vojenských testovacích oblastech, je v dnešní době zásadní krok. Současné metody jsou totiž závislé na omezených údajích o explozivních látkách a jejich dopadech na životní prostředí.</p><p>Běžně používané explozivní látky, jako jsou nitroaromáty a nitraminy, představují poměrně vysoké riziko kontaminace životního prostředí, přičemž nitraminy jsou navíc vysoce mobilní. Navzdory své reaktivitě jsou tyto látky za běžných podmínek v přírodě poměrně stabilní Například TNT může v půdě přetrvávat desítky let, zejména v oblastech s omezeným přístupem kyslíku a nízkou mikrobiální aktivitou. Významným příkladem dlouhodobé kontaminace je oblast Kolberger Heide v Baltském moři, kam byla po druhé světové válce hromadně ukládána munice. Studie z roku 2025 potvrdila přítomnost metabolitů TNT v moči a žluči ryb, což potvrzuje bioakumulaci explozivních látek v mořských organismech a jejich přetrvávání v životním prostředí po více než osm desetiletí.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/ALS_Czech_Republic_obrazek_2_a_3_776f20a518.jpg" alt="ALS Czech Republic: Nahoře vzorec TNT (2,4,6-trinitrotoluen), dole: vzorec RDX/Hexogen (hexahydro-1,3,5-trinitro-5-triazin)" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_ALS_Czech_Republic_obrazek_2_a_3_776f20a518.jpg 144w," sizes="100vw" width="629" height="683"></p><h4><strong>Analýza výbušnin</strong></h4><p>Implementace přesných analytických metod umožňuje spolehlivou i dentifikaci a k vantifikaci širokého spektra explozivních látek, včetně jejich degradačních produktů, antioxidantů a propelantů. Zavedení těchto metod reflektuje rostoucí potřebu monitoringu exploziv v civilních i vojenských zdrojích.</p><p>Americká agentura pro ochranu životního prostředí (EPA) používá pro analýzu nitroaromatických látek, nitraminů a nitrátových esterů metodu 8330B (SW-846) pomocí HPLC, což je standardizovaná metoda, která zajišťuje přesné analytické výsledky.</p><p>V ALS se při zpracování a přípravě vzorků dodržují postupy dané příslušnými standardy a samotné analýzy jsou prováděny na <strong>nejmodernějších systémech HPLC-DAD poslední generace</strong>.<br>Každý pozitivní nález je nejprve ověřen na základě spektrální shody a následně konfirmován pomocí alternativní stacionární fáze chromatografické kolony. Tento postup zajišťuje vysokou spolehlivost naměřených dat.</p><h4><strong>Seznam látek, které je možno analyzovat:</strong></h4><ul><li><strong>Oktahydro-1,3,5,7-tetranitro-1,3,5,7-tetrazocin (HMX / Oktogen)</strong> – CAS: 2691-41-0</li><li><strong>Hexahydro-1,3,5-trinitro-1,3,5-triazin (RDX / Hexogen)</strong> – CAS: 121-82-4</li><li><strong>1,3,5-trinitrobenzen (1,3,5-TNB)</strong> – CAS: 99-35-4</li><li><strong>1,3-dinitrobenzen (1,3-DNB)</strong> – CAS: 99-65-0</li><li><strong>Methyl-2,4,6-trinitrofenyl-nitramin (Tetryl / CE)</strong> – CAS: 479-45-8</li><li><strong>Nitrobenzen (NB)</strong> – CAS: 98-95-3</li><li><strong>2,4,6-trinitrotoluen (2,4,6-TNT)</strong> – CAS: 118-96-7</li><li><strong>4-Amino-2,6-dinitrotoluen (4-Am-DNT)</strong> – CAS: 19406-51-0</li><li><strong>2-Amino-4,6-dinitrotoluen (2-Am-DNT)</strong> – CAS: 35572-78-2</li><li><strong>2,4-dinitrotoluen (2,4-DNT)</strong> – CAS: 121-14-2</li><li><strong>2,6-dinitrotoluen (2,6-DNT)</strong> – CAS: 606-20-2</li><li><strong>2-nitrotoluen (2-NT)</strong> – CAS: 88-72-2</li><li><strong>3-nitrotoluen (3-NT)</strong> – CAS: 99-08-1</li><li><strong>4-nitrotoluen (4-NT)</strong> – CAS: 99-99-0</li><li><strong>Nitroglycerin (glycerol trinitrát, NG)</strong> – CAS: 55-63-0</li><li><strong>Pentaerythritol tetranitrát (PETN)</strong> – CAS: 78-11-5</li><li><strong>3,5-dinitroanilin (3,5-DNA)</strong> – CAS: 618-87-1</li><li><strong>Difenylamin (DPA / Dpha)</strong> – CAS: 122-39-4</li><li><strong>N-nitrosodifenylamin (NDPhA)</strong> – CAS: 86-30-6</li></ul><h4><strong>Požadavky na vzorek:</strong></h4><ul><li><strong>Voda:</strong> ideálně 2 l vzorku bez sedimentů, vzorkovnice z tmavého skla</li><li><strong>Půda:</strong> ideálně 200 g vzorku, plastová nádoba (sáček/kelímek/vzorkovnice - obr. 4)</li></ul><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/ALS_Czech_Republic_vzorek_pro_exploziva_be8281c68c.jpg" alt="ALS Czech Republic: Obrázek 4: Polypropylenová vzorkovnice pro odběr pevných vzorků (půdy). Máte-li zájem o analýzu exploziv, kontaktujte nás, vzorkovnice vám budou dodány." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_ALS_Czech_Republic_vzorek_pro_exploziva_be8281c68c.jpg 156w," sizes="100vw" width="458" height="458"></p><blockquote><p><strong>Poznámka k odběrové nádobě: </strong>vzorky vody musí být odebírány a přepravovány POUZE v lahvích z tmavého skla, aby se zabránilo možné fotodegradaci cílových analytů. Vzorky půdy tmavou plastovou vzorkovnici nevyžadují, vzorky půdy nejsou transparentní jako voda a fotodegradace nedosahuje takového stupně.</p></blockquote><h4><strong>První testy a výsledky</strong></h4><p>První výsledky z laboratoře ALS ukazují na možné pozitivní nálezy hexogenu (RDX) v analyzovaných vzorcích, přičemž koncentrace ve vzorcích vod dosahují až desítek μg/l, v půdních vzorcích byly zjištěny hodnoty až v jednotkách mg/kg (sušiny původního vzorku). Ačkoli v současné době neexistují žádné legislativní požadavky na systematické monitorování explozivních látek v životním prostředí, zvýšené povědomí a porozumění těmto látkám jsou podnětem k postupným legislativním změnám.</p><p>Například Kanada v roce 2020 zavedla povinné monitorování hexogenu (RDX) ve vodách používaných pro výrobu pitné vody s limitní hodnotou 100 μg/l, a to celé z důvodu pozitivních nálezů RDX v povrchových a podzemních vodách v blízkosti vojenských základen.&nbsp;</p><p>Zavedení nových akreditovaných metod podle mezinárodních standardů představuje zásadní krok k efektivnímu monitoring explozivních látek v životním prostředí. Výsledky potvrzují přítomnost těchto polutantů v půdě a ve vodách a podtrhují tak nutnost jejich systematického sledování. Získaná data jsou klíčová nejen pro hodnocení environmentálních rizik, ale také pro navrhování vhodných sanačních opatření.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/ALS_exploziva_chromatogram_3438c12b83.jpg" alt="ALS Czech Republic: 1,3-Dinitrobenzen; (6) 3,5-Dinitroanilin; (7) Tetryl; (8) Nitrobenzen; (9) Nitroglycerin; (10) 2,4,6-trinitrotoluen; (11) 4-amino-2,6 -Dinitrotoluen; (12) 2-Amino-4,6-Dinitrotoluen; (13) 2,6-Dinitrotoluen; (14) 2,4-dinitrotoluen; (15) 2-nitrotoluen; (16) 4-nitrotoluen; (17) 3-nitrotoluen; (1) PETN; (19) N-nitrosodifenylamin; (20) Difenylamin." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_ALS_exploziva_chromatogram_3438c12b83.jpg 245w," sizes="100vw" width="2008" height="849"></p><h4><strong>Doba analýzy (TAT):</strong></h4><ul><li><strong>Výsledky stanovení výbušnin</strong> budou dodány <strong>do 10 - 14 dnů</strong> v závislosti na typu matrice.</li><li><strong>Expresní analýza NENÍ možná </strong>z důvodu technologických kroků zpracování vzorků.</li></ul><blockquote><p class="cke-user_style-important"><a target="_blank" rel="noopener noreferrer" href="https://forms.office.com/Pages/ResponsePage.aspx?id=TqBcSHRvUECXZM20v6icJbMPu9EliIpOlmKAr1xVTFtUMU5YNDAxUjRONUtaSTJDSVZYR1pVNzkzUS4u&amp;origin=QRCode"><strong>Kontaktujte naše experty</strong></a></p></blockquote>

EnviroMail™28: Moderní metody stanovení explozivních látek v životním prostředí

<p><strong>Zveme Vás na třináctý ročník konference České společnosti pro hmotnostní spektrometrii, která proběhne společně s jedenáctým Neformálním proteomickým setkáním ve dnech 19. 11. - 21. 11. 2025 v Českých Budějovicích.</strong></p><h3><strong>Registrace</strong></h3><blockquote><p class="cke-user_style-important"><strong>👉</strong><a target="_blank" rel="noopener noreferrer" href="https://www.czechms.org/cz/events/cmsc/registration.php"><strong>Registrace CMSC 2025</strong></a></p><ul><li>On-line registrace: <strong>od </strong>soboty <strong>22. března</strong> <strong>do pondělí 3. listopadu 2025</strong></li><li>Po tomto termínu bude možné přihlášení <strong>pouze na místě</strong>.</li></ul></blockquote><h3><strong>Program</strong></h3><h4><strong>Středa 19. listopadu 2025</strong></h4><h5><strong>10:00 - 18:00 Registrace</strong></h5><h5><strong>12:45 - 13:45 </strong>Oběd, jídelna - Biologické centrum AVČR</h5><h5><strong>13:45 - 14:00 Zahájení konference</strong></h5><h5><strong>14:00 - 15:00 Plenární přednáška I: Prof. Alexander Makarov (Thermo Fisher Scientific)&nbsp;</strong></h5><h5><strong>15:00 - 16:00 Sekce I</strong></h5><h5><strong>15:00 - 15:20 </strong><a target="_blank" rel="noopener noreferrer" href="https://www.czechms.org/cz/events/cmsc/abstract.php?code=8123077"><strong>WeO-01</strong></a><strong>: Towards MS-guided Precision Environmental Health: the Czech node of the European Research Infrastructure for Human Exposome Research</strong></h5><ul><li>Elliott James Price</li></ul><h5><strong>15:20 - 15:40 </strong><a target="_blank" rel="noopener noreferrer" href="https://www.czechms.org/cz/events/cmsc/abstract.php?code=3900926"><strong>WeO-02</strong></a><strong>: Optimization of microflow LC-MS method by design of experiments and its application to proteomics analysis</strong></h5><ul><li>Urban Jiří</li></ul><h5><strong>15:40 - 16:00 </strong><a target="_blank" rel="noopener noreferrer" href="https://www.czechms.org/cz/events/cmsc/abstract.php?code=5590880"><strong>WeO-03</strong></a><strong>: Simultaneous mapping of peptides and released N-glycans by HILIC-FLD-MS for quality control of protein biopharmaceuticals</strong></h5><ul><li>Starovoit Mykyta</li></ul><h5><strong>16:00 - 16:30 </strong>Přestávka na kávu</h5><h5><strong>16:30 - 16:50 Sponzorská přednáška – </strong><a target="_blank" rel="noopener noreferrer" href="https://lcms.cz/companies/51"><strong>Phenomenex</strong></a></h5><h5><strong>16:50 - 18:10 Sekce II</strong></h5><h5><strong>16:50 - 17:10 </strong><a target="_blank" rel="noopener noreferrer" href="https://www.czechms.org/cz/events/cmsc/abstract.php?code=7077801"><strong>WeO-04</strong></a><strong>: G-quadruplex – ligand interaction biophysics explored by native mass spectrometry and trapped ion mobility spectrometry</strong></h5><ul><li>Melikov Aleksandr</li></ul><h5><strong>16:50 - 17:10 </strong><a target="_blank" rel="noopener noreferrer" href="https://www.czechms.org/cz/events/cmsc/abstract.php?code=4284116"><strong>WeO-05</strong></a><strong>: Insights into CyRepA2 primase-helicase-DNA interactions using structural mass spectrometry</strong></h5><ul><li>Smrčka Tomáš</li></ul><h5><strong>16:50 - 17:10 </strong><a target="_blank" rel="noopener noreferrer" href="https://www.czechms.org/cz/events/cmsc/abstract.php?code=6642100"><strong>WeO-06</strong></a><strong>: Breaking the Unbreakable: Structural Elucidation of the Hypermodified RiPP Nostatin A by IRMPD Mass Spectrometry</strong></h5><ul><li>Hájek Jan</li></ul><h5><strong>16:50 - 17:10 </strong><a target="_blank" rel="noopener noreferrer" href="https://www.czechms.org/cz/events/cmsc/abstract.php?code=4468653"><strong>WeO-07</strong></a><strong>: Unraveling Oligomerization-Mediated Inhibition in GGPPS by Structural Mass Spectrometry</strong></h5><ul><li>Portašiková Jasmína</li></ul><h5><strong>18:10 - 18:30 Sponzorská přednáška – Genetica</strong></h5><p><strong>18:30 - 19:00 Flash Talks I</strong></p><h5><strong>Quantification of Oxoacids of the Human Metabolome using Liquid Chromatography-Mass Spectrometry </strong><a target="_blank" rel="noopener noreferrer" href="https://www.czechms.org/cz/events/cmsc/abstract.php?code=4124815"><strong>(WeS-01)</strong></a></h5><ul><li>Hebesberger Philipp</li></ul><h5><strong>Analyses of human scent samples </strong><a target="_blank" rel="noopener noreferrer" href="https://www.czechms.org/cz/events/cmsc/abstract.php?code=9840543"><strong>(WeS-02)</strong></a></h5><ul><li>Škeříková Veronika</li></ul><h5><strong>rDUVLAESCI-MS/MSI: a novel approach for direct analysis of biological surfaces </strong><a target="_blank" rel="noopener noreferrer" href="https://www.czechms.org/cz/events/cmsc/abstract.php?code=5983681"><strong>(WeS-03)</strong></a></h5><ul><li>Grepl Jakub</li></ul><h5><strong>Investigation of phenolic compounds in grape pomace through UHPLC-ESI-MS/MS </strong><a target="_blank" rel="noopener noreferrer" href="https://www.czechms.org/cz/events/cmsc/abstract.php?code=8595826"><strong>(WeS-04)</strong></a></h5><ul><li>Jágr Michal</li></ul><h5><strong>Mass Spectral Library Network (MERLIN) To Streamline The Generation Of Public Spectral Libraries </strong><a target="_blank" rel="noopener noreferrer" href="https://www.czechms.org/cz/events/cmsc/abstract.php?code=7046316"><strong>(WeS-05)</strong></a></h5><ul><li>Brigante Federico</li></ul><h5><strong>A Comprehensive timsTOF MS/MS Spectral Library for Improving Metabolite Annotation in Non-Targeted Metabolomics </strong><a target="_blank" rel="noopener noreferrer" href="https://www.czechms.org/cz/events/cmsc/abstract.php?code=5455392"><strong>(WeS-06)</strong></a></h5><ul><li>Mazumdar Aninda</li></ul><h5><strong>19:00 - 22:0 </strong>Raut (jídelna, živá hudba od 19:30)</h5><h4><strong>Čtvrtek 20. listopadu 2025</strong></h4><h5><strong>09:00 - 09:40 Workshop </strong><a target="_blank" rel="noopener noreferrer" href="https://lcms.cz/companies/42"><strong>Pragolab</strong></a></h5><h5><strong>09:40 - 10:40 Sekce III</strong></h5><h5><strong>09:40 - 10:00 </strong><a target="_blank" rel="noopener noreferrer" href="https://www.czechms.org/cz/events/cmsc/abstract.php?code=5116751"><strong>ThO-08</strong></a><strong>: Low-input proteomics using the Orbitrap Astral</strong></h5><ul><li>Talacko Pavel</li></ul><h5><strong>10:00 - 10:20 </strong><a target="_blank" rel="noopener noreferrer" href="https://www.czechms.org/cz/events/cmsc/abstract.php?code=6944556"><strong>ThO-09</strong></a><strong>: Integrated multiomics classification of triple negative breast cancer</strong></h5><ul><li>Bouchal Pavel</li></ul><h5><strong>10:20 - 10:40 </strong><a target="_blank" rel="noopener noreferrer" href="https://www.czechms.org/cz/events/cmsc/abstract.php?code=5588120"><strong>ThO-10</strong></a><strong>: Proteomics of human breast milk</strong></h5><ul><li>Konik Peter</li></ul><h5><strong>10:40 - 11:00 Sponzorská přednáška – Amedis</strong></h5><h5><strong>11:00 - 11:30 </strong>Přestávka na kávu</h5><h5><strong>11:30 - 12:10 Workshop Genetica</strong></h5><h5><strong>12:10 - 13:10 Sekce IV</strong></h5><h5><strong>12:10 - 12:30 </strong><a target="_blank" rel="noopener noreferrer" href="https://www.czechms.org/cz/events/cmsc/abstract.php?code=5278447"><strong>ThO-11</strong></a><strong>: Development-dependent molecular strategies of stress adaptation in plants</strong></h5><ul><li>Černý Martin</li></ul><h5><strong>12:30 - 12:50 </strong><a target="_blank" rel="noopener noreferrer" href="https://www.czechms.org/cz/events/cmsc/abstract.php?code=4462363"><strong>ThO-12</strong></a><strong>: Deciphering adaptive shifts in the redox proteome of wheat seedlings under drought</strong></h5><ul><li>Danchenko Maksym</li></ul><h5><strong>12:50 - 13:10 </strong><a target="_blank" rel="noopener noreferrer" href="https://www.czechms.org/cz/events/cmsc/abstract.php?code=7250720"><strong>ThO-13</strong></a><strong>: No Mark, No Problem: Alternative Epigenetic Silencing in Algae</strong></h5><ul><li>Lochmanová Gabriela</li></ul><h5><strong>13:10 - 14:00 </strong>Oběd</h5><h5><strong>14:00 - 14:50 Plenární přednáška II: Prof. Bernhard Kuster (Technical University of Munich)&nbsp;</strong></h5><h5><strong>14:50 - 15:40 Flash Talks II</strong></h5><h5><strong>Propionic acid boosts sensitivity in high-flow RPLC-MS proteomics compared to formic and acetic acid </strong><a target="_blank" rel="noopener noreferrer" href="https://www.czechms.org/cz/events/cmsc/abstract.php?code=3643222"><strong>(ThS-07)</strong></a></h5><ul><li>Lenčo Juraj</li></ul><h5><strong>Towards Biomarker Discovery: Multiomics analysis of Endometriosis </strong><a target="_blank" rel="noopener noreferrer" href="https://www.czechms.org/cz/events/cmsc/abstract.php?code=8104565"><strong>(ThS-08)</strong></a></h5><ul><li>Oždian Tomáš</li></ul><h5><strong>Integrated proteogenomic analysis identifies synuclein gamma as a key target of the mesenchymal stem-like subtype of triple negative breast cancer </strong><a target="_blank" rel="noopener noreferrer" href="https://www.czechms.org/cz/events/cmsc/abstract.php?code=6375703"><strong>(ThS-09)</strong></a></h5><ul><li>Šimoník Jan</li></ul><h5><strong>Human IMPs: A tool for comparing outputs of different tools for transmembrane segment predictions in the human proteome </strong><a target="_blank" rel="noopener noreferrer" href="https://www.czechms.org/cz/events/cmsc/abstract.php?code=5382082"><strong>(ThS-10)</strong></a></h5><ul><li>Vít Ondřej</li></ul><h5><strong>LC-MS/MS-based terminomics unravels role of carboxypeptidase B1 in luminal A breast cancer </strong><a target="_blank" rel="noopener noreferrer" href="https://www.czechms.org/cz/events/cmsc/abstract.php?code=6248138"><strong>(ThS-11)</strong></a></h5><ul><li>Lapčík Petr</li></ul><h5><strong>Mass spectometry in hands of experimental biology: Impaired nucleotide salvage affects de novo synthesis in Drosophila melanogaster </strong><a target="_blank" rel="noopener noreferrer" href="https://www.czechms.org/cz/events/cmsc/abstract.php?code=9618906"><strong>(ThS-12)</strong></a></h5><ul><li>Sysel Jakub</li></ul><h5><strong>Bioaccumulation of pharmaceuticals in herbivorous fish: The role of aquatic plants as a dietary source </strong><a target="_blank" rel="noopener noreferrer" href="https://www.czechms.org/cz/events/cmsc/abstract.php?code=5574795"><strong>(ThS-13)</strong></a></h5><ul><li>Hinterholzová Helena</li></ul><h5><strong>LC-HRMS for large-scale chemical exposure studies </strong><a target="_blank" rel="noopener noreferrer" href="https://www.czechms.org/cz/events/cmsc/abstract.php?code=8545306"><strong>(ThS-14)</strong></a></h5><ul><li>Koudelka Štěpán</li></ul><h5><strong>15:40 - 17:00 </strong>Přestávka na kávu + posterová sekce</h5><h5><strong>17:00 - 17:40 Workshop Bruker</strong></h5><h5><strong>17:40 - 18:00 Přednáška laureáta ceny prof. Josefa Chmelíka</strong></h5><h5><strong>18:00 - 18:20 Schůze ČSHS, přednášková místnost</strong></h5><h5><strong>18:00 - 18:20 Schůze Proteomické sekce ČSBMB, posterová místnost</strong></h5><h5><strong>19:00 - 22:00 </strong>Slavnostní večeře – Restaurace Solnice</h5><h5><strong>21:00 Volitelná prohlídka Českých Budějovic s průvodcem – sraz na náměstí u kašny</strong></h5><h4><strong>Pátek 21. listopadu 2025</strong></h4><h5><strong>09:00 - 09:50 Plenární přednáška III: Prof. Jana Roithová (Radboud University)</strong></h5><h5><strong>09:50 - 10:50 Sekce V</strong></h5><h5><strong>09:50 - 10:10 </strong><a target="_blank" rel="noopener noreferrer" href="https://www.czechms.org/cz/events/cmsc/abstract.php?code=2187982"><strong>FrO-15:</strong></a><strong> Per- and polyfluorinated compounds (PFAS) in wild common bream</strong></h5><ul><li>Grabicová Kateřina</li></ul><h5><strong>10:10 - 10:30 </strong><a target="_blank" rel="noopener noreferrer" href="https://www.czechms.org/cz/events/cmsc/abstract.php?code=8460763"><strong>FrO-16:</strong></a><strong> Spatial mapping of 15N-labeled ammonia with MALDI-FTICR imaging in regenerating liver tissue: Re-directing of toxic byproduct into anabolic pathways</strong></h5><ul><li>Kučera Lukáš</li></ul><h5><strong>10:30 - 10:50 </strong><a target="_blank" rel="noopener noreferrer" href="https://www.czechms.org/cz/events/cmsc/abstract.php?code=5845173"><strong>FrO-17</strong></a><strong>: LC-ICP-MS analysis of anti-obesity peptides and their metabolites labeled with lanthanide mass-tag</strong></h5><ul><li>Čechová Aneta</li></ul><h5><strong>10:50 - 11:00 Sponzorská přednáška – </strong><a target="_blank" rel="noopener noreferrer" href="https://lcms.cz/companies/43"><strong>Shimadzu</strong></a></h5><h5><strong>11:00 - 11:20 </strong>Přestávka na kávu</h5><h5><strong>11:20 - 11:40 Sponzorská přednáška – Bruker</strong></h5><h5><strong>11:40 - 13:00 Sekce VI</strong></h5><h5><strong>11:40 - 12:00 </strong><a target="_blank" rel="noopener noreferrer" href="https://www.czechms.org/cz/events/cmsc/abstract.php?code=3584762"><strong>FrO-18</strong></a><strong>: Advancing Gut Microbiome Metabolomics: A Derivatization-Based Approach</strong></h5><ul><li>Stefani Tommaso</li></ul><h5><strong>12:00 - 12:20 </strong><a target="_blank" rel="noopener noreferrer" href="https://www.czechms.org/cz/events/cmsc/abstract.php?code=1987314"><strong>FrO-19</strong></a><strong>: Mass Spectrometry in Drug Development: From Screening to Stability and Pharmacokinetics</strong></h5><ul><li>Chalupský Karel</li></ul><h5><strong>12:20 - 12:40</strong><a target="_blank" rel="noopener noreferrer" href="https://www.czechms.org/cz/events/cmsc/abstract.php?code=7700719"><strong> FrO-20</strong></a><strong>: Mass spectrometry of human body odor: Signatures of psychophysiological states</strong></h5><ul><li>Kyjakova Pavlina</li></ul><h5><strong>12:40 - 13:00 </strong><a target="_blank" rel="noopener noreferrer" href="https://www.czechms.org/cz/events/cmsc/abstract.php?code=7256314"><strong>FrO-21:</strong></a><strong> Population-scale human chemical exposomics by automated liquid-liquid extraction coupled to gas chromatography – Orbitrap mass spectrometry</strong></h5><ul><li>Coufalíková Kateřina</li></ul><h5><strong>13:00 - 13:10 Závěr konference, vyhlášení cen</strong></h5><h5><strong>13:10 - 14:00 </strong>Oběd</h5><h5><strong>14:00 - 17:40 Prohlídka pivovaru Budvar nebo jaderné elektrárny Temelín s průvodcem</strong></h5>

Program 13. České konference hmotnostní spektrometrie 2025 a 11. Neformálního proteomického setkání

Životní prostředí

Věda a výzkum

Článek

Video

Nejbližší akce

Základním posláním společnosti ALS je pomáhat našim klientům se kvalifikovaně a informovaně rozhodovat tím, že poskytuje spolehlivá, konzistentní a reprodukovatelná laboratorní data. Zaručujeme spolehlivé výsledky, krátké dodací lhůty, nepřetržitý provoz, odbornou podporu a odběry vzorků.

ALS Czech Republic

Cílem společnosti je napomáhat rozvoji hmotnostní spektrometrie v České republice, poskytovat svým členům a dalším osobám se zájmem o hmotnostní spektrometrii podporu v získávání znalostí v oboru, prezentovat dosažené pokroky a rozšiřovat obecné povědomí o hmotnostní spektrometrii ve společnosti. ČSHS bude spolupracovat se zahraničními společnostmi zaměřenými na hmotnostní spektrometrii, přispívat ke zvyšování odborné úrovně svých členů, organizovat semináře, konference a vědecká setkání.

Česká společnost pro hmotnostní spektrometrii

Univerzita Palackého v Olomouci je vysoká škola s dlouhou tradicí. Byla založena již v 16. století a je tak nejstarší vysokou školou na Moravě a druhou nejstarší v České republice. V současnosti představuje moderní vzdělávací instituci se širokou nabídkou studijních oborů a bohatou vědeckou činností.

Univerzita Palackého v Olomouci

New Food magazine

Technology Networks

Bruker

Phenomenex

Wiley

Shimadzu Corporation

SCIEX

Waters Corporation

<div><h4><strong>Elevate Your DLS Knowledge</strong></h4><p><strong>Join us for the last 2 series on DLS and Dynamics! Optimize formulation development and understand particle concentration like never before.</strong></p><h4><strong>Session Overview:</strong></h4><ul><li><h5><strong>Part 4 of 5: High-Throughput DLS: Optimizing Formulation Development</strong></h5><ul><li>Friday, November 7&nbsp;</li></ul></li><li><strong>Part 5 of 5:</strong> Particle Concentration by DLS: Why Light Scattering Works, Even When ELISA is Wrong<ul><li>Friday, November 14</li></ul></li></ul><h4><strong>Why Attend:</strong></h4><ul><li>Deepen your understanding of DLS &amp; Dynamics.</li><li>Gain actionable insights for your lab.</li><li>Interact with our expert, Dr. Andy Meyer.</li></ul><p>The live interactive web series are 100% live sessions, with anonymous Q&amp;A welcome during and after the discussion. Free for all Wyatt customers.</p><blockquote><p><strong>Hosted by:</strong> Dr. Andy Meyer</p><p>Dr. Andy Meyer joined Wyatt Technology in 2001, serving for several years as an Applications Scientist, then as Dean of Wyatt's "Light Scattering University" and as Director of Customer Service &amp; Support. After managing multiple regions in North America, Dr. Meyer is now a Senior Application Scientist for Wyatt. As a Wyatt customer, he completed his Ph.D. in Applied Science – Polymer Chemistry from the College of William and Mary in Virginia.</p></blockquote></div>

Waters Corporation: Becoming a DYNAMICS Expert

Becoming a DYNAMICS Expert: Part 4

Discover how high-throughput DLS accelerates formulation development. Join live and ask your questions anonymously with Dr. Andy Meyer on November 7.

<p><strong>Join Lorena Manzano as she demonstrates how advanced HRMS technology provides the sensitivity and confidence needed to monitor chemical contaminants, protecting both agricultural productivity and public health.</strong></p><p>This webinar will provide an overview of advanced high-resolution mass spectrometry (HRMS) strategies for monitoring pharmaceuticals and pesticides in complex environmental and agricultural matrices. Lorena Manzano will share recent findings on the occurrence, persistence and potential transfer of these contaminants from reclaimed water to soils and crops, highlighting how innovative analytical solutions can support safer water reuse practices.</p><p>Water scarcity and the increasing use of reclaimed water for irrigation create both opportunities and challenges for agriculture. While reuse contributes to sustainability, it also introduces chemical contaminants into the food chain. Conventional monitoring approaches often fail to provide the sensitivity, selectivity and robustness required to detect low-level residues in highly complex samples such as soils and edible plant tissues.</p><p>This webinar will address these challenges by discussing the role of HRMS, with a particular focus on how ZenoTOF technology enhances confidence in compound identification and quantification. Attendees will learn about key trends in environmental risk assessment, the importance of tracking persistent pharmaceuticals such as carbamazepine, and the role of multi-residue analysis in ensuring food safety.</p><p>Case studies from real-world greenhouse experiments will be presented, demonstrating examples of pharmaceutical and pesticide transfer from wastewater to soils and edible crops. Finally, the session will provide actionable insights into how cutting-edge HRMS can be integrated into monitoring programmes to better protect both agricultural productivity and public health.</p><h5><strong>You will learn:</strong></h5><ul><li>Understand the occurrence and persistence of pharmaceuticals and pesticides in reclaimed water, irrigated soils, and edible crops.</li><li>Explore how HRMS ZenoTOF technology enhances detection, identification, and quantification of contaminants in complex matrices.</li><li>Learn from greenhouse case studies on pharmaceutical and pesticide accumulation under real-world irrigation practices.</li><li>Identify key challenges and opportunities for safe wastewater reuse in agriculture and food safety monitoring.</li></ul><blockquote><p><strong>Presenter:</strong> Lorena Manzano Sánchez, PHD, University of Almería</p><p>Lorena Manzano, PhD in Analytical Chemistry from the University of Almería, is an expert in advanced chromatographic and mass spectrometric techniques. With over six years of experience at the European Union Reference Laboratory for Fruits and Vegetables (EURL-FV), her work has focused on the application of LC- and GC-based high- and low-resolution mass spectrometry for the monitoring of pesticide residues in plant-derived matrices.</p></blockquote>

New Food Magazine: Protecting the food chain: Advanced HRMS strategies for contaminants in water and soil

Protecting the food chain: Advanced HRMS strategies for contaminants in water and soil

Webinar on advanced HRMS strategies for detecting pharmaceuticals and pesticides in water, soil, and crops to support safe reuse and protect public health.

Advanced HRMS for Contaminant Detection in Water & Soil

<div><p><strong>The microbiome plays a crucial role in health, disease, and ecological balance, making its analysis essential for advancements in various fields such as medical research, food industry studies, and environmental science. In this regard, metaproteomics offers a powerful and efficient method to gain rapid insights into both the composition and activity of the microbiome by identifying, characterizing, and quantifying microbial proteins.</strong></p><p>This webinar will provide an overview of the sample preparation and mass spectrometry analysis stages involved in metaproteomics. Additionally, it will demonstrate the potential of this approach through a practical case study analyzing the effects of prebiotics on a fecal microbiome. Join us to explore how metaproteomics can enhance your research and provide deeper insights into microbial activity.</p><blockquote><p><strong>Presenter:</strong> Morten Danielsen, Ph.D., Head of Metabolomics &amp; Proteomics Business Unit, Cmbio, Copenhagen, Denmark</p><p>Morten Danielsen, Ph.D., is the head of the Metabolomics and Proteomics Business unit at Cmbio. He has a scientific background as a microbiologist and has worked with analytical chemistry since 2010. He founded MS-Omics in 2014, together with Lea G. Johnson, which grew into a leading metabolomics provider in Europe. Later MS-Omics merged with Clinical-Microbiomics, CosmosID and DNASense to create a leading microbiome and multi-omics service provider/CRO named Cmbio. Cmbio has labs in Europe and the US, and a global team presence.</p><p><br><strong>Presenter:</strong> Adam Hughes, Key Account Manager, Northern Europe, PreOmics, Manchester, UK</p><p>Adam joined PreOmics in 2024, with over 15 years of experience in the life sciences industry. PreOmics offers a comprehensive suite of sample preparation and proteomics solutions. Adam focuses on separation science, particularly sample preparation and chromatography, helping customers optimize their workflows and achieve reliable, reproducible results. Adam’s background includes a Master’s degree in Chemistry and more recently an MBA with the Open University, blending scientific expertise with commercial insight.</p><p><br><strong>Presenter:</strong> Pierre-Olivier Schmit, Proteomics Business Development Manager, Bruker Daltonics, Bordeaux, France</p><p>Pierre-Olivier Schmit joined Bruker in 2000 as an MS application and Demo scientist, after a double training in chemistry (Ecole Nationale Supérieure de Chimie de Montpellier) and biochemistry (university of Lund &amp; Montpellier) and a first experience in developing proteomics approaches (CNRS/Pierre Fabre).He took the head of the French demo lab, taking care of customer support, training and demo operations, and reinforcing an expertise in protein characterization and proteomics. He gradually shifted to a market management position from 2012 on, focusing on bottom-up and top-down proteomics approaches. Since 2021, he is acting as a proteomics business development manager for Western, Nordic and southern Europe.</p></blockquote></div>

Bruker: Metaproteomics as a tool to map prebiotic action

Metaproteomics as a tool to map prebiotic action

This webinar will provide an overview of the sample preparation and mass spectrometry analysis stages involved in metaproteomics. 

<div><p><strong>Red blood cells (RBCs) offer a unique and minimally invasive window into neurodegeneration, yet their potential as a source of Parkinson’s disease biomarkers is only beginning to be explored.</strong></p><p>This webinar will showcase state-of-the-art mass spectrometry (MS) platforms that are able to identify protein signatures linked to earlier detection and improved disease monitoring. Our expert speaker will share new findings from RBC proteomics research, offering attendees a look at how this exciting area of proteomics and high-resolution MS may advance our understanding and clinical management of Parkinson’s disease.</p><h5><strong>Attend this webinar to:&nbsp;</strong></h5><ul><li>Understand the rationale for using RBCs in biomarker discovery for Parkinson’s disease</li><li>Learn how advanced MS workflows, such as data-independent acquisition and trapped ion mobility spectrometry – time-of-flight, enable deep proteome coverage</li><li>Review bioinformatics and statistical approaches for candidate biomarker identification and validation</li><li>Explore the translational potential of RBC proteomics for clinical applications</li></ul><blockquote><p><strong>Presenter:</strong> Blaine Roberts, PhD (Associate Professor Department of Biochemistry, Emory University)</p><p>Dr. Roberts is an Associate Professor in the Department of Biochemistry and Department of Neurology at Emory University. He obtained his Bachelor of Science in Chemistry at Montana State University and his PhD in Biochemistry and Biophysics from Oregon State University. His research group focuses on using protein biochemistry and mass spectrometry to understand Alzheimers, Parkinson’s and amyotrophic lateral sclerosis. He has interest in understanding the role of metals in biology and has developed new proteomic technologies to measure metalloproteins. Further, his group is using mass spectrometry and next generation quantitative assays for the development of new blood borne biomarkers for Alzheimers and Parkinson’s disease.</p></blockquote></div>

Bruker: Uncovering Parkinson’s Biomarkers Through Red Blood Cell Proteins

Uncovering Parkinson’s Biomarkers Through Red Blood Cell Proteins

Parkinson’s Biomarkers - Red Blood Cell Proteins

<p><strong>In this webinar, we will present a solid phase extraction (SPE) method for quantifying GalNAc-conjugated siRNA in plasma and liver matrices, and will explore how optimizing key method parameters can significantly boost recovery rates and enhance analytical performance.</strong></p><h4><strong>Key Learning Points</strong></h4><ul><li>Review key sample pre-treatment method strategies for the successful and improved recovery of GalNAC-conjugated siRNA in plasma and liver tissue.</li><li>Explore how find how Clarity OTX Pro SPE strategies differ when extracting ASOs versus GalNAc-conjugated siRNA oligonucleotides.</li><li>Learn how to choose the right Clarity OTX Pro well plate format for oligonucleotide extraction in complex matrices.</li></ul><h4><strong>Who Should Attend</strong></h4><ul><li>Anyone looking to begin or improve &nbsp;extraction of GalNAc-conjugated siRNA duplex oligonucleotides from plasma or liver samples using solid phase extraction (SPE).</li></ul><blockquote><p><strong>Speaker:</strong> Mihir Thakar (Product Manager, Phenomenex)</p><p>Mihir holds a master’s degree in Biotechnology. He has over a decade of experience working with various biopharma companies in the characterization of therapeutic peptides, proteins, and oligonucleotides. He has been associated with Phenomenex for more than 7 years, serving in various functions including as a Business Development Manager for Biologics. At present, he has been working as a Global Product Manager for the biopharma segment.&nbsp;</p><p><strong>Speaker: </strong>Roxana Eggleston-Rangel (Senior Applications Scientist, Phenomenex)</p><p>Roxana joined Phenomenex in 2018 as an Applications Scientist and is currently working with the applications team to produce analytical solutions for the biopharma industry. Her current work focuses on characterization of mRNA, sgRNA and siRNA. Prior to Phenomenex, Roxana worked for Caltech and the University of Southern California developing LM-CS workflows for the proteomics community. She received her bachelor’s and master’s degree in Chemistry and Biochemistry from California State University, Los Angeles.</p></blockquote>

Phenomenex: New Clarity OTX Pro – Case Study: GalNAc siRNA Quantitation by SPE-LC-MS

New Clarity OTX Pro – Case Study: GalNAc siRNA Quantitation by SPE-LC-MS

In this webinar, we will present a solid phase extraction (SPE) method for quantifying GalNAc-conjugated siRNA in plasma and liver matrices

Clarity OTX Pro – GalNAc siRNA Quantitation by SPE-LC-MS

<div><p><strong>Two powerful single cell analytical methods have propelled the field of cell biology forward. Microscopy established the concept of a single cell over 300 years ago and has revealed thousands of features that are currently used to differentiate cells and delineate the processes of maturation and disease. Conventional flow cytometry is limited in the number of morphological and spatial features measured, but it is highly quantifiable both in the number of cells analyzed and the accuracy of measurements. Imaging flow cytometry (IFC) combines the strengths of both systems. Importantly, while conventional flow cytometry analysis has been particularly vital in the field of immunology, there have been challenges in applying it to cells that are defined by morphology and for which there are few distinguishing flow cytometry antibodies available. Thus, for these reasons, we turned to IFC in our studies of erythropoiesis.</strong></p><h4><strong>Key topics discussed in this webinar will include:</strong></h4><ul><li>Delineating stages of erythropoiesis from early progenitor to terminal maturation with flow cytometry and IFC</li><li>Issues and potentials for examining microenvironmental interactions with erythroid cells in bone marrow, particularly with macrophages</li><li>Improving flow cytometry analysis by using IFC to remove artifacts</li><li>Synergizing single cell assays by integrating morphology and fluorescence analysis on the same cell</li><li>Combining advances in computer analysis with the inherent analytical power of human visual processing to manage the high dimensionality of IFC data</li></ul><h4><strong>Who should attend:</strong></h4><ul><li>Researchers using IFC who wish to enhance and expand their assay repertoire&nbsp;</li><li>Scientists considering adding IFC to their single cell analysis tool kit</li><li>Scientists studying erythroid differentiation and macrophage interactions</li><li>Anyone interested in imaging and flow cytometry applications</li></ul><blockquote><p><strong>Presenter:</strong> Dr. Kathleen McGrath (Research Associate Professor, University of Rochester Medical Center)</p></blockquote></div>

Wiley: Utilizing Imaging Flow Cytometry To Empower Studies Of Erythropoiesis

Utilizing Imaging Flow Cytometry To Empower Studies Of Erythropoiesis

Learn how IFC enhances single-cell analysis by integrating morphology and fluorescence to study erythropoiesis and macrophage interactions in bone marrow.

Imaging Flow Cytometry To Study Erythropoiesis

<h4><strong>Tackling toxicology challenges with SCIEX technology</strong></h4><p><strong>Join us for an insightful session on SCIEX advanced forensic screening and quantitation solutions, designed to tackle the evolving challenges in the forensic toxicology laboratory.</strong></p><p>Discover how accurate mass spectrometry and high-sensitivity workflows empower forensic laboratories to detect and quantify a broad spectrum of compounds with confidence, including new psychoactive substances (NPS).</p><p>We will showcase the capabilities of the ZenoTOF 7600 system for drug screening, characterization, and identification, as well as the utility of the vMethod for NPS screening. The presentations will also highlight the improvements in speed, sensitivity, and analyte coverage using our SCIEX 7500+ system, as well as the benefits of the QTRAP systems for fast, selective, and confident detection and identification of NPS from human whole blood.</p><p>Learn how our solutions streamline complex analyses, reduce false positives, and enhance data reliability.</p><p>Hear from experts on real-world applications, including emerging drug trends and regulatory demands. Whether you are focused on toxicology, drug screening, or forensic casework, this summit will provide actionable insights to elevate your lab’s performance.</p><h4><strong>Agenda</strong></h4><h5><strong>10:00 – 10:05 Welcome</strong></h5><ul><li>Nina Unkelbach, SCIEX</li></ul><h5><strong>10:05 – 10:25 SCIEX product line and technology update</strong></h5><ul><li>Dr. Jianru Stahl-Zeng, SCIEX</li></ul><h5><strong>10:25 – 11:05 Method application with ZenoTOF 7600: a comprehensive solution for drugs and new psychoactive substances (NPS) screening</strong></h5><ul><li>Aymeric Morla, SCIEX</li></ul><h5><strong>11:05 – 11:35 Simultaneous identification and quantitation of NPS in human whole blood using QTRAP technology</strong></h5><ul><li>Dr. Jianru Stahl-Zeng, SCIEX</li></ul><h5><strong>11:35 – 12:05 Capabilities of the SCIEX 7500+ system for identification and quantification of drugs and metabolites at trace levels.</strong></h5><ul><li>Oscar Quintela, SCIEX</li></ul><h5><strong>12:05 Farewell</strong></h5><blockquote><p><strong>Speaker:</strong> Dr. Jianru Stahl-Zeng</p><p>Jianru is Senior Technical Marketing Manager. She has been part of SCIEX since 2001. She initially was part of the application support team and covered not only proteomics, but also small molecules applications. Jianru moved to technical marketing and focused on food and environmental applications. Since 2018 she has been managing the EMEA technical marketing team and projects. Jianru is also the Global Technical Leader for food and environmental applications.</p><p><strong>Speaker:</strong> Aymeric Morla</p><p>Aymeric is Applications Lead for Clinical &amp; Forensic solutions, based in Paris. With a background in biochemistry, he developed his expertise in clinical and forensic analysis during the last 18 years. He works closely with forensic laboratories across Europe, helping them implement and optimize mass spectrometry workflows for toxicology, drug screening, and trace analysis. Aymeric brings hands-on expertise in regulated environments and is passionate about translating complex analytical technologies into practical, high-impact forensic applications.</p><p><strong>Speaker:</strong> Oscar Quintela</p><p>Oscar earned a Bachelor of Science in Pharmacy from the University of Santiago de Compostela, followed by a PhD with European doctorate distinction, Maxima Cum Laude, supported by a Ministry of Science and Education grant. His career has focused on clinical and forensic toxicology, including doctoral research on detecting psychotropic drugs in biological samples via LC-MS/MS for driving population studies. Supported by a fellowship from the National Institute on Drug Abuse (NIH, USA), he continued researching drugs of abuse during his postdoctoral stage. After over 12 years at the Spanish Ministry of Justice, he joined SCIEX about three years ago.</p></blockquote>

SCIEX: SCIEX forensic winter school: From trace to truth

SCIEX forensic winter school: From trace to truth

Join us for a session on SCIEX advanced forensic screening and quantitation solutions, designed to tackle challenges in forensic toxicology laboratory.

<div><p><strong>Quality control and quality assurance are cornerstones of good scientific practice. However, tools for ensuring instrument fitness, monitoring system performance, and evaluating data quality are lacking in the small molecule bioanalysis fields, creating an unmet need that labs are left to solve individually.</strong></p><p>In this webinar, we will discuss QSee™, a unique solution integrating tools for quality control in small molecule bioanalysis. QSee™ allows simple and automated instrument fitness assessment, and long-term instrument performance monitoring.</p><p>Dr. Sven Meyer will introduce the QSee™ solution, and Dr. Christoph Trautwein as well as Dr. Jannik Spregel will discuss how their lab has been using the QSee™ suite in their ongoing metabolomics research.</p><ul><li><strong>QSee™ Performance Test: </strong>A convenient and user-friendly software solution that automates the standardized acquisition and analysis of a performance testing mixture. It enables users to monitor system fitness and long-term performance, while also helping to reduce the complexity of troubleshooting and instrument servicing.</li><li><strong>QSee™ 8-Mix: </strong>A stable mixture of eight water-soluble small molecule compounds, designed for use with the QSee Performance Test software to enable standardized data acquisition and analysis.</li><li><strong>TwinScape™:</strong> A cloud-based digital twin solution for storing and comparing instrument health and quality control data. It facilitates long-term monitoring of instrument performance and paves the way for predictive maintenance, supporting more efficient and quality-assured operations.</li></ul><h4><strong>Key Learning Objectives:</strong></h4><ul><li>Learn how the QSee™ Performance Test Solution can support your lab's quality control workflows&nbsp;</li><li>Understand the value of longitudinal and cross-platform system performance monitoring&nbsp;</li><li>Discover the benefits of TwinScape™ for system performance monitoring</li></ul><h4><strong>Who should attend:</strong></h4><ul><li>Researchers in metabolomics and lipidomics interested in automating quality control workflows for small molecule bioanalysis</li><li>Investigators and lab heads searching for efficient, easy to implement performance monitoring tools for LC-timsTOF - devices</li></ul><blockquote><p><strong>Presenter:</strong> Christoph Trautwein, Ph.D., Director Core Facility Metabolomics, University of Tübingen Hospital/M3 Research Center, Tübingen, Germany</p><p>Dr. Christoph Trautwein is the head of the Core Facility Metabolomics at the Medical Faculty University of Tübingen and research group leader for Metabolomics &amp; Systems Medicine. In his labs, Dr. Trautwein and his team apply latest quantitative NMR spectroscopy, four-dimensional timsTOF LC-MS and high-resolution MALDI Imaging based metabolomics and lipidomics. His personal research interests are cancer, neurodegeneration, microbiome research and quantitative precision diagnostics.</p><p><strong>Presenter: </strong>Jannik Sprengel, Ph.D., Core Facility Metabolomics, University of Tübingen Hospital/M3 Research Center, Tübingen, Germany</p><p>Dr. Jannik Sprengel is the deputy head and laboratory supervisor of the Core Facility Metabolomics at the M3 Research Center of the University Clinic of Tübingen. As trained analytical food chemist, he brings more than 6 years of experience in chromatography and mass spectrometry to the Metabolomic field through his Ph.D. in environmental chemistry and previous work as analytical scientist for the food monitoring authorities.</p><p><strong>Presenter: </strong>Sven Meyer, Ph.D., Applications Development, Bruker Daltonics, Bremen, Germany</p><p>Sven Meyer holds a doctoral degree in chemistry with a background in structural elucidation of novel natural products based on NMR and Mass Spectrometry. He is with Bruker since 15 years, and is working in the Applications Development team. His current focus is on small molecule applications using the timsTOF and timsMetabo platforms.&nbsp;</p></blockquote></div>

Bruker: QC simplified: Streamlining Quality Control in Small Molecule Research

QC simplified: Streamlining Quality Control in Small Molecule Research

In this webinar, we will discuss QSee™, a unique solution integrating tools for quality control in small molecule bioanalysis. 

Quality Control in Small Molecule Research

<p><strong>Evolving regulations in food safety and environmental monitoring demand faster, more accurate results—without increasing costs. In this Digital Classrooms session, discover how Shimadzu’s comprehensive suite of solutions for elemental analysis can help you meet these challenges head-on, no matter the complexity of your analysis requirements.</strong></p><p>Discover Shimadzu’s versatile solutions designed to meet diverse analytical challenges:</p><ul><li><strong>ALTRACE EDXRF</strong>: Achieve rapid, non-destructive screening with minimal sample preparation and exceptional sensitivity reaching ppb levels.</li><li><strong>ICPMS 2040/2050: </strong>Deliver precise quantification with the added advantage of reduced argon gas consumption and optimized operating costs.</li><li><strong>LC-ICPMS: </strong>Go beyond total elemental content to identify and quantify chemical species of elements, hence enabling detailed evaluation of the benefits and/or risks associated with the elements present in a sample.</li></ul><p>Whether you're screening incoming raw materials, confirming regulatory compliance for food safety, monitoring environmental contaminants, or conducting speciation studies, this session will equip you with the right tools to optimize workflows, enhance data quality, and achieve superior results. Join us to discover practical applications, expert insights, and actionable strategies to stay ahead in a rapidly evolving landscape.</p><h4><strong>Learning Objectives:</strong></h4><ul><li>Gain insights into the latest regulations for elemental analysis</li><li>Explore Shimadzu’s innovative solutions for achieving accurate, high-throughput elemental analysis</li><li>Discover how ALTRACE simplifies and accelerates elemental analysis for greater efficiency.</li></ul><blockquote><p><strong>Presenter:</strong> Goh Wan Yu Elton (Market Specialist For Food And Environmental, Shimadzu (Asia Pacific) Pte Ltd)</p><p>Elton dedicates his career to food analytics, ensuring the safety and quality of our daily consumption. As a Food Specialist at Shimadzu, he develops and applies advanced analytical techniques to detect and quantify compounds in food products, from contaminants to nutrients. Elton takes pride in advancing food science, enhancing safety, and building consumer trust. His goal is to make valuable contributions to analytical chemistry and the global food industry.</p><p><strong>Presenter:</strong> Tan Teck Beng (Principal Product Specialist, Shimadzu (Asia Pacific) Pte Ltd)</p><p>Tan Teck Beng is the Principal Product Specialist for Scientific Instruments at Shimadzu Asia Pacific. He holds a Master’s degree in Materials Science from the National University of Singapore and has over 24 years of experience in materials characterization and analytical techniques. His expertise spans XRF, EPMA, SPM, XPS, OES, and XRD. Mr. Tan has conducted numerous seminars and workshops across Asia, focusing on materials analysis, failure investigation, and RoHS compliance. He is recognized for his extensive technical support and training contributions to scientists and engineers in advanced material characterization.</p></blockquote>

Shimadzu: Elemental Analysis Made Easy: Innovative Solutions For Food & Environmental Testing

Elemental Analysis Made Easy: Innovative Solutions For Food & Environmental Testing

Discover Shimadzu’s ALTRACE, ICPMS, and LC-ICPMS solutions for efficient, precise elemental analysis in food safety and environmental monitoring.

Elemental Analysis For Food & Environmental Testing

<div><p><strong>Data quality begins at the very first step of your workflow: sample handling. This short webinar explores two critical risks: analyte degradation through pH shift and analyte loss through non-specific-binding (NSB). These two factors can compromise large- and small molecule samples alike. Learn how TruView pH Control vials safeguard analytes again alkaline degradation, and how QuanRecovery with MaxPeak™ HPS minimized sample loss by reducing non-specific binding. Discover how controlling these hidden variables leads to higher recovery, control of your analysis, more consistent results and greater confidence in your data.</strong></p><p>Understand pH drift in sample vials, and how it can lead to degradation<br>Recognize the impact of NSB on recovery and data accuracy<br>How you can leverage technologies for improving data certainty</p><blockquote><p><strong>Presenter:</strong> Markus Wanninger (Principal Product Manager, Waters Corporation)</p><p>Markus is the principal product manager of sample vials and plates. He has a degree in chemical engineering and long-standing experience in the pharmaceutical industry. Markus has a keen understanding of the needs of analytical HPLC laboratories, and the controls required to have certainty in results and staying in compliance. The drive to control and optimize processes enabled the Markus and the vials team to drive continuous improvement of product lines to meet the demands of todays’ laboratories. Outside his professional life Markus is a passionate photographer and an inspiring chef and pitmaster.</p></blockquote></div>

Waters Corporation: Ensuring confidence in data through smarter sample handling

Ensuring confidence in data through smarter sample handling

Discover how Waters TruView and QuanRecovery technologies prevent analyte loss and pH drift, improving data quality and consistency in analytical workflows.

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