Je mu třicet let, se špičkovým výzkumem začal před maturitou a jeho jméno nese asteroid. Robin Kryštůfek zkouší základní výzkum i prostředí biotechnologických firem. „Jsou to propojené světy,“ říká v podcastu CHEmic.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/UOCHB_Tomas_Bellon_Podcast_CH_Emic_73_Existuji_mista_kde_stihnete_delat_vynikajici_vedu_cestou_na_obed_4d7e661cf9.jpg" alt="ÚOCHB/Tomáš Belloň – Podcast CHEmic #73 – Existují místa, kde stihnete dělat vynikající vědu cestou na oběd." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_UOCHB_Tomas_Bellon_Podcast_CH_Emic_73_Existuji_mista_kde_stihnete_delat_vynikajici_vedu_cestou_na_obed_4d7e661cf9.jpg 218w," sizes="100vw" width="2000" height="1433"><blockquote>Podcast CHEmic představuje vědce a vědkyně z Ústavu organické chemie a biochemie AV ČR, jejich život v labech i mimo ně.</blockquote><blockquote>CHEmic najdete v podcastových aplikacích:</blockquote><blockquote><ul><li><a target="_blank" rel="noopener noreferrer" href="https://open.spotify.com/show/0ELIQTRkC3TFrVYnZgztsy?si=b4407e1f54824315&amp;nd=1">Spotify</a></li><li><a target="_blank" rel="noopener noreferrer" href="https://podcasts.apple.com/cz/podcast/podcast-chemic-1-riskovat-se-vyplat%C3%AD-ne%C3%BAsp%C4%9Bchu-se-nesm%C3%ADme/id1683797089?i=1000611870620">Apple Podcasts</a></li><li><a target="_blank" rel="noopener noreferrer" href="https://podcasts.google.com/feed/aHR0cHM6Ly9hbmNob3IuZm0vcy9kZmFhNjA4OC9wb2RjYXN0L3Jzcw">Podcasty Google</a></li></ul></blockquote><blockquote>a na našem <a target="_blank" rel="noopener noreferrer" href="https://www.youtube.com/playlist?list=PLFJNDHHAxyMszoY-Hm4BGJ6nN7zNLZXO-">YouTube kanálu</a>.</blockquote>

Podcast CHEmic #73 – Existují místa, kde stihnete dělat vynikající vědu cestou na oběd

Plnění požadavků směrnice EU o pitné vodě: klíčová role přípravy vzorků při analýze stopových kontaminantů

Ačkoliv moderní zemědělství potřebuje vycházet z přesných dat o půdních, rostlinných i environmentálních podmínkách v reálném čase, cenově dostupná, dostatečně citlivá a zároveň robustní monitorovací zařízení pro tento účel v současné době chybí. Jako vhodné řešení se podle vědců nabízí nízkonákladové senzory založené na nových chytrých materiálech a technologiích tisku. Dosavadní výsledky multiioborového výzkumu i návrhy na vývoj těchto zařízení představili výzkumníci z Česka, Velké Británie, Španělska i USA v přehledovém článku v prestižním časopise <a target="_blank" rel="noopener noreferrer" href="https://www.nature.com/articles/s41467-026-68778-6#Abs1">Nature Communications</a>.„Senzorické technologie pro monitorování zdraví rostlin jsou stále v plenkách. Na trhu jsou běžné dostupné jen jednoduché senzory, které jsou schopné monitorovat pouze základní parametry jako například pH, vlhkost v půdě, případně teplotu. Pokud však mají zemědělci čelit současným výzvám včetně klimatických změn a zajistit pro lidstvo dostatek potravy, potřebují mnohem účinnější pomocníky, jež jim umožní monitorovat například i různé patogeny včetně bakterií či plísní. Podle nás je vhodným řešením kombinace nových chytrých materiálů a tisku pro produkci levných, odolných a škálovatelných materiálů,“ uvedl první autor článku David Panáček z CATRIN, který na studii pracoval během své stáže v Imperial College London.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/CATRIN_Soucasne_senzory_nestaci_Vedci_navrhuji_novou_cestu_ke_sledovani_zdravi_rostlin_b4014952a3.jpg" alt="CATRIN: David Panáček" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_CATRIN_Soucasne_senzory_nestaci_Vedci_navrhuji_novou_cestu_ke_sledovani_zdravi_rostlin_b4014952a3.jpg 208w," sizes="100vw" width="1536" height="1152">Senzory pro monitorování zdraví rostlin například v porovnání s podobnými zařízeními pro humánní medicínu pokulhávají. Klíčovou roli v možném posunu hraje podle autorů pokrok v materiálových vědách, jenž vývoj škálovatelných senzorových technologií umožní. „Tiskové techniky včetně inkoustového tisku, sítotisku, aerosolového tisku, 3D tisku a přímého laserového zápisu nabízejí flexibilní cesty k výrobě ohebných senzorů, senzorů pro velké plochy i senzorů integrovaných přímo do rostlin. Přehledový článek shrnuje nedávný pokrok v oblasti tisknutelných nízkorozměrných materiálů pro zemědělské senzory, analyzuje jejich fyzikálně-chemické vlastnosti ve vztahu k senzorovému výkonu a diskutuje hlavní výzvy a budoucí příležitosti vyžadující mezioborovou integraci,“ uvedl jeden z korespondujících autorů Michal Otyepka.Výzkum propojil materiálové vědce, chemiky, biology, odborníky na senzing i technologie tisku. Materiálový výzkum a využití chytrých materiálů na bázi grafenu zaštítili vědci CATRIN Univerzity Palackého a VŠB-Technické univerzity Ostrava, znalostmi o vývoji rostlin, jejich reakcích na stresové podmínky i monitorování jejich vlastností přispěli rostlinní biologové z CATRIN, o oblast elektroniky se postarali výzkumníci z Imperial College London, technologiím tisku se věnovali zástupci <a target="_blank" rel="noopener noreferrer" href="https://lcms.cz/companies/36">CEITEC – VUT</a>. V týmu nechyběli ani přední odborníci na senzing z Katalánského institutu nanověd a nanotechnologií v Barceloně a svými bohatými znalostmi přispěl i „otec senzingu a elektrochemie“ Joseph Wang z University of California San Diego.„Jedná se o průlomovou studii na toto téma, k níž se podařilo přizvat skutečně velká jména v daných oborech. V neposlední řadě studie dokládá to, že interdisciplinarita v CATRIN dává vzniknout zcela novým a perspektivním výzkumným tématům, jako je rostlinný senzing a jeho využití pro studium interakce rostlin s prostředím a chytrém zemědělství,“ doplnila další z korespondenčních autorů Nuria De Diego. &nbsp;

Současné senzory nestačí. Vědci navrhují novou cestu ke sledování zdraví rostlin

Osobnosti

Životní prostředí

Vědecký článek

Popularizace

Věda a výzkum

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Článek

ÚOCHB AV ČR je přední mezinárodně uznávaná vědecká instituce, jejímž hlavním posláním je základní výzkum v oblasti chemické biologie a medicinální chemie, organické a materiálové chemie, chemie přírodních látek, biochemie a molekulární biologie, fyzikální chemie, teoretické chemie a analytické chemie.

Ústav organické chemie a biochemie AV ČR

Český institut výzkumu a pokročilých technologií (Czech Advanced Technology and Research Institute – CATRIN) je vysokoškolský ústav Univerzity Palackého v Olomouci. Vznikl integrací vědeckých týmů Centra regionu Haná pro biotechnologický a zemědělský výzkum (CRH), Regionálního centra pokročilých technologií a materiálů (RCPTM) a Ústavu molekulární a translační medicíny (ÚMTM) s cílem úzce propojit vědecké kapacity v oblasti biomedicíny, nanotechnologií, nových materiálů, výzkumu rostlin či biotechnologií a ještě úspěšněji čelit  globálním výzvám současného světa, k nimž patří například dopady klimatických změn, boj s novými typy patogenů, diagnostika a léčba civilizačních onemocnění, odvrácení hrozící potravinové krize, získávání a ukládání „zelené“ energie, zajištění dostatku pitné vody, ochrana životního prostředí a řada dalších.

CATRIN

Společnost Organomation, založená v roce 1959, navrhuje a vyrábí vysoce kvalitní dusíkové koncentrátory a extrakční systémy. Jejich laboratorní přístroje, známé svou inovativností a odolností, se používají po celém světě pro efektivní přípravu vzorků a jsou doprovázeny silnou zákaznickou podporou.

Organomation

New Food magazine

Separation Science

Agilent Technologies

BioLogic

Bruker

Restek Corporation

Shimadzu Corporation

Evosep Biosystems

Waters Corporation

<div>SpaceM is proud to introduce two pioneering methods built on Bruker mass spectrometry technology, HT SpaceM and 13C-SpaceM, that are set to transform drug discovery and precision medicine.<ul><li>HT SpaceM: A high-throughput method for single-cell metabolomics, offering improved cell preparation, advanced MALDI Imaging, and custom multi-well slides. Detect diverse small molecules with high reproducibility and gain deeper insights into cellular metabolism.</li><li>13C-SpaceM: Study metabolic activity in single cells and tissues through spatial and isotope tracing of glucose-dependent de novo lipogenesis. Uncover single-cell differences and metabolic reprogramming in cancer cells, providing valuable insights into fatty acid dynamics.</li></ul>These approaches provide deeper insights into cellular functions, metabolic pathways, and drug toxicity, addressing challenges that bulk methods miss. Join us in pushing the boundaries of single-cell analysis and exploring how these innovations can enhance your research and development efforts.<blockquote>Presenter: Shawn Owens, Ph.D. (Imaging Mass Spectrometrist, SpaceM, BioInnovation Institute, Copenhagen, Denmark)</blockquote></div>

Bruker: Single Cell Metabolomics: Revealing cellular diversity using isotope tracing

Single Cell Metabolomics: Revealing cellular diversity using isotope tracing

SpaceM is proud to introduce two pioneering methods built on Bruker mass spectrometry technology, HT SpaceM and 13C-SpaceM.

Single Cell Metabolomics: Revealing cellular diversity

Join our upcoming panel discussion to hear from industry experts as they discuss the new regulations around PFAS, along with the challenges and approaches to managing the issues.In the coming years, the implementation of food safety testing regulations will expand globally. The prevalence of PFAS across the supply chain, concerns around health impacts, dietary risk exposure and supply chain assurance are all components of these soon-to-be implemented requirements.Currently, the EU and China regulate a limited regulatory framework encompassing a small list of PFAS compounds in food, ingredients, beverages and feed. However, the EU has proposed an expanded list in Commission with approximately 29 compounds proposed and further expansion expected over the coming years is all part of the current discussion. The REACH updates in 2025 are expected to impact packaging and process control, while in the United States, AOAC (AOAC SMPR 2023.003) has ratified a proposed method to test residues of up to 40 PFAS chemicals incurred in food and feed.These regulations could have an impact on production and supply in the food value chain and drive a need for more testing and mapping of PFAS in foodstuffs.With the potential of new PFAS method regulations, come new testing challenges. Although AOAC haven’t fully ratified the PFAS method, it has been approved as a standard method performance requirement, it still brings the potential addition of new compounds to the testing regimen which in turn brings analytical challenges and the approach to this analysis is as critical as the choice of supplier to assure consumers that the food they consume is as safe and risk-free as they expect.&nbsp;Key learning points:&nbsp;<ul><li>Explore the evolving food safety regulatory landscape and the impact of new technologies.</li><li>Discuss collaboration opportunities between companies and regulators to improve compliance.</li><li>Evaluate strategies for identifying and managing food safety risks within the supply chain.</li><li>Focus on the role of data analytics in promoting &nbsp;transparency and proactive risk management.</li></ul><blockquote>Presenter: Moderator – Professor Chris Elliot (Professor of Food Safety at Queen’s University Belfast)Chris is Professor of Food Safety and Founder of the Institute for Global Food Security at Queen’s University Belfast. He served as Pro Vice Chancellor responsible for the Medical and Life Sciences Faculty between 2015 and 2018 and has published more than 450 peer-reviewed articles, many of them relating to the detection and control of agriculture, food, and environmental contaminants.Presenter: Lorna De Leoz (Global Food Segment Manager, Agilent Technologies)&nbsp;Lorna De Leoz, Ph.D., has numerous years of experience in the food industry as a bench chemist, graduate researcher, and mass spectrometry specialist. She is currently Global Food Segment Manager at Agilent Technologies. Previously she was a Research Chemist at the National Institute of Standards and Technology where she led a global study on the glycosylation of monoclonal antibodies and extended the scope of the NIST mass spectral libraries to include oligosaccharides. Lorna completed her Ph.D. in Chemistry at the University of California, Davis where her research focused on understanding the role of milk oligosaccharides in infant gut flora.Presenter: Erin S. Baker, Ph.D. (Associate Professor, University of North Carolina at Chapel Hill)&nbsp;To date, she has published over 190 peer-reviewed papers utilizing different analytical chemistry techniques to study both environmental and biological systems. She is currently serving as the Vice President of Education for the International Lipidomics Society, a mentor for Females in Mass Spectrometry, and an Associate Editor for the Journal of the American Society for Mass Spectrometry. She has received seven US patents, two R&amp;D 100 Awards, been named to the 2019, 2021, 2023, and 2024 Analytical Scientist Top 100 Power Lists, and was a recipient of the 2016 ACS Rising Star Award for Top Midcareer Women Chemists, 2022 ASMS Biemann Medal, and 2022 IMSF Curt Brunnée Award. Currently, her research group utilizes advanced separations and novel software capabilities to examine how chemical exposure affects human health.</blockquote>

New food magazine: PFAS: Navigating regulations, challenges, risk management and testing in the food supply chain

PFAS: Navigating regulations, challenges, risk management and testing in the food supply chain

A panel discussion with industry experts as they discuss the new regulations around PFAS, along with the challenges and approaches to managing the issues.

 PFAS: Regulations, challenges, testing in the food

Glycosylation is a widespread protein modification involved in almost all important biological processes, making it an appealing topic for clinical studies. However the analytical and biochemical complexity associated with glycoproteomics analyses has prevented a widespread adoption of this approach as a tool for clinical research studies.&nbsp;In this webinar, Dr. Hans Wessels from the Radboud University Medical Center (Nijmegen, Netherlands) highlights how real-time search driven PASEF acquisitions and advanced bioinformatics help you ushering into glycoproteomics. He will describe the enabling technological building blocks and present real-life examples of their use for clinical research and patient care.<blockquote>Presenter: Hans Wessels, Ph.D. (Proteomics Scientist, Radboud University, Nijmegen, Netherlands)</blockquote>

Bruker: Translational clinical glycoproteomics in practice

Translational clinical glycoproteomics in practice

Dr. Hans Wessels highlights how real-time search driven PASEF acquisitions and advanced bioinformatics help you ushering into glycoproteomics.

By attending this webinar, you will:<ul><li>Learn about method development steps undertaken to provide a robust and sensitive method for sample preparation of antibiotics in honey</li><li>Gain an understanding of the Biotage sample preparation workflow and the benefits of automation</li><li>Discover the challenges faced when developing a sample preparation method for antibiotics in honey</li></ul>Event OverviewThis presentation will detail different approaches to sample preparation for the analysis of antibiotics from honey prior to analysis on LC-MS/MS (Liquid Chromatography coupled to tandem Mass Spectrometry). It will compare different solid phase extraction (SPE) techniques to traditional QuEChERS and present Biotage's automatable cartridge SPE for QuEChERS clean-up.We will also discuss method development steps undertaken to fully optimize different sample preparation procedures for effective matrix removal and optimal recoveries for a panel of antibiotics from honey. The presentation will cover challenges faced during the development stages along with actions taken to overcome the issues as we develop an efficient sample preparation method. We will highlight the benefits of automating the methods within a laboratory to free up analysts' time and ensure good reproducibility.The presentation is aimed at laboratories that undertake food analysis and are interested in optimizing the clean-up of their food samples to produce accurate and reliable results. The focus will be on the best strategies used to fully remove matrix interferences while maintaining high recoveries and good reproducibility in honey testing.<blockquote>Presenter: Thomas Smith (EMEA Applications Laboratory Team Leader, Biotage)Thomas has been with Biotage since July 2022 and is supporting customers to streamline their sample preparation approaches and help them automate their manual, labour-intensive tasks in the laboratory. Prior to this, Thomas worked in a toxicology lab analyzing hair for drugs of abuse and alcohol markers. His main role was to automate a method to increase reproducibility and turnaround time to meet the growing sample numbers.</blockquote>

Separation Science: How to Prepare Honey Samples for Efficient Analysis of Antibiotics

How to Prepare Honey Samples for Efficient Analysis of Antibiotics

This presentation will detail different approaches to sample preparation for the analysis of antibiotics from honey prior to analysis on LC-MS/MS

How to Prepare Honey Samples for Analysis of Antibiotics

PROteolysis-Targeting Chimeras (PROTACs) represent a novel approach in drug design that offers significant advantages, including the ability to target proteins and prosecute therapeutic concepts previously considered beyond inhibitors. PROTACs are increasingly established within pharmaceutical development pipelines, advancing from early-stage discovery into clinical trials. Their unique structure introduces new mechanisms for targeted protein degradation, providing opportunities for more effective and sustained treatment options.We are pleased to share this symposium as an educational opportunity to learn about structure, mechanism and analytical characteristics of PROTACs.Take a look at the symposium lineup:<h5>Keynote Presentation: PROTACs: From Hit ID to in vivo Efficacy</h5><ul><li>Dr William Farnaby, Principal Investigator, Centre for Targeted Protein Degradation, University of Dundee, UK</li></ul>This educational presentation will focus on leanings from a recent disclosure on the discovery of panKRAS PROTACs as part of a collaboration between the University of Dundee Centre for Targeted Protein Degradation and Boehringer-Ingelheim (Popow et al., Science 385, 1338–1347 (2024)). Dr Farnaby will use the case study to expand key elements of PROTAC discovery and optimization.<h5>Optimization of an end-to-end workflow for bioanalytical quantification of PROTACs&nbsp;</h5><ul><li>Nikunj Tanna: Principle Scientist, Waters Corporation, US</li></ul><h5>A Comparison of Pharmacokinetic Parameters of Gefitinib and Gefitinib based PROTACs- 3 by optimised LC-MS/MS&nbsp;</h5><ul><li>Amy Bartlett: Principle Market Development Manager, Waters Corporation, UK</li></ul><h5>Solving the Challenge of Protein Degrader Metabolite ID: The Metabolic Fate of PROTACs based Gefitinib in the Rat &nbsp;</h5><ul><li>Dr Rob Plumb: Consultant Scientist, Waters Corporation, US</li></ul> Key Learning Points<ul><li>The latest in PROTACs design and optimization for therapeutic applications.</li><li>Cutting-edge techniques for bioanalysis and pharmacokinetics.</li><li>In-depth insights into metabolite profiling of PROTAC-based drugs.</li></ul><blockquote>Presenter: Dr William Farnaby (Principal Investigator, Centre for Targeted Protein Degradation, University of Dundee, UK)Dr William Farnaby is a Principal Investigator within the University of Dundee Centre for Targeted Protein Degradation. He has recently been awarded EPSRC New Investigator and Wellcome Trust Early Career awards, supporting his long-term vision for using induced proximity chemistry to address and understand diseases of the central nervous system. Previously, Dr William Farnaby led a large Targeted Protein Degradation drug discovery team, as part of a collaboration between the University of Dundee and Boehringer-Ingelheim. He has been a key contributor to major, highly cited advances in the field of targeted protein degradation and in particular in the area of structure based PROTAC design. Prior to this, he co-invented multiple clinical candidates for CNS diseases as a medicinal chemist at Takeda, including the CH24Hi drug for Dravet syndrome, Soticlestat.Presenter:&nbsp;Nikunj Tanna (Principle Scientist, Waters Corporation, US)Nikunj Tanna is a Principal Scientist at Waters corporation. His role at Waters focuses on complete workflow solutions for quantitation of small and large molecules. He has a particular emphasis on sample preparation and automation for bioanalysis, ADME and DMPK applications. In his previous role as General supervisor and Bioanalytical scientist at Berg LLC, he led a clinical diagnostics team focused on providing PK support for the company’s small molecule drug candidates.Presenter:&nbsp;Amy Bartlett (Principle Market Development Manager, Waters Corporation, UK)Amy has long established expertise in quantitative LC-MS/MS analysis and throughout her 18 years at Waters, has led teams of experienced applications scientists providing application and scientific support to Waters' customers across a broad range of markets, applications, and technologies. Prior to this, Amy worked for several years in the pharmaceutical industry in Analytical Development and Discovery DMPK roles.Presenter:&nbsp;Dr Rob Plumb (Consultant Scientist, Waters Corporation, US)Dr Plumb has published over 160 papers on the subject of HPLC/MS and NMR for bioanalysis, metabolomics and metabolite identification. After obtaining Ph. D in Analytical Chemistry in 1999, he worked at Glaxo Research and Development Drug Metabolism Department. During his time at Glaxo and later GlaxoWellcome, he continued his research in liquid chromatography combined with NMR and mass spectrometry for metabolite identification. In 2001, he moved to Waters Corporation in Milford, MA, USA where he has worked in R&amp;D, pharmaceutical marketing, metabolic phenotyping and discovery omics. He is currently a scientific advisor for the Research, Discovery and Analytical Testing function.</blockquote>

Waters Corporation: The Future of Drug Discovery: A Symposium on PROTACs from Lead Optimization to Pharmacokinetics and Metabolite Identification

The Future of Drug Discovery: A Symposium on PROTACs from Lead Optimization to Pharmacokinetics and Metabolite Identification

We are pleased to share this symposium as an educational opportunity to learn about structure, mechanism and analytical characteristics of PROTACs.

The Future of Drug Discovery: A Symposium on PROTACs 

Whisper™ Zoom is designed to push the boundaries of sensitivity in proteomics, enabling you to work with even the most limited samples while maintaining high data quality.Join this webinar to learn more about our latest advencement for the Whisper Zoom methods, enabling sensitive and scalable workflows.<h4>Single-cell proteomics profiling of pancreatic islets from healthy, type 1 diabetes donors, and stem cell-derived model using whisper zoom.</h4><ul><li>Talk by Pierre Sabatier, Researcher at Novo Nordisk Foundation Center for Protein Research, University of Copenhagen.</li></ul>Combining the Evo 96 proteochip workflow on the cellenONE sorter and whisper zoom on the Evosep One, we profiled single pancreatic islets cells from healthy, type 1 diabetes donors, and in a stem cell-derived model. We quantified 3000-4000 proteins per cell despite their small size, allowing cell-type identification by markers, including insulin, glucagon, somatostatin, and pancreatic polypeptide. We uncover key biological features such as elevated levels of TNF-α in T1D cells pointing to ongoing inflammation and markers indicating the lack of maturation of stem cell-derived islets. Our study reveals disease-relevant insights and explore cellular diversity within pancreatic islets.<h4>Recommendations for Quantitative Proteomics using Data Independent Acquisition-Lessons from Controlled Quantitative Experiments</h4><ul><li>Talk by Andrew Frey, Postdoctoral Research Associate at Newcastle University</li></ul>Efficacy of protein quantitation is seeing increased interest in the proteomics community-especially in novel methods where low sample input or high throughput is considered. Here, we perform a series of controlled quantitative experiments (CQEs), subjecting defined proteome mixtures to Whisper Zoom 20SPD and diaPASEF on an Evosep LC in line with a timsToF-HT. We identified &gt;10,000 unique proteins and &gt;160,000 precursors across samples. Post processing was found to have drastic impacts on ID rates, quantitative precision and accuracy. We present recommendations for data processing, and advice on the use of CQEs when assessing quantitative efficacy in novel modes of acquisition. &nbsp;

Evosep Biosystems: Whisper zoom combines ease-of-use and simplicity for routine, high-sensitivity workflows

Whisper zoom combines ease-of-use and simplicity for routine, high-sensitivity workflows

Single-cell proteomics profiling of pancreatic islets from healthy, type 1 diabetes donors, and stem cell-derived model using whisper zoom.

Ease-of-use and simplicity for high-sensitivity workflows

Fuel cells and electrolyzers are paving the way for a sustainable energy future. But unlocking their full potential demands a deep understanding of the electrochemical processes at work.Electrochemical methods are essential for understanding the complex phenomena underlying the operation of electrolyzers and fuel cells, advancing clean energy innovation.This webinar offers three focused sessions:<ul><li>Scientific Insights: Francisco Jose Fernandez Carretero will explore key research questions addressed through potentiostats and other electrochemical techniques.</li><li>Best Practices: Olivier Roux will discuss Electrochemical Impedance Spectroscopy (EIS), emphasizing how to avoid experimental artifacts and ensure accurate measurements.</li><li>Advanced Tools: Cedric Georges will present BioLogic’s cutting-edge instruments, optimized for advanced electrochemical research.</li></ul>The session will conclude with a Q&amp;A, providing attendees an opportunity to engage directly with the speakers.Hosted by Dr. Lindsey Monger and Dr.GianLuca Santoni, this webinar will provide actionable strategies for both academic and industrial researchers.

BioLogic: Electrochemical methods for the characterization of electrolyzers and fuel cells

Electrochemical methods for the characterization of electrolyzers and fuel cells

This webinar will provide critical insights into electrochemical methods and best practices, helping you refine your research and achieve more reliable results.

Electrochemical methods for electrolyzers and fuel cells

Separation of molecules based on chirality poses several challenges. Those challenges are fortified when separation methods need to be optimized to minimize run time and use of resources.&nbsp;Join us as we show off Shimadzu’s sophisticated set of environmentally friendly solutions geared toward efficient separation of chiral and achiral molecules.We will host a Q&amp;A session after the presentation to address any questions or comments.<blockquote>Presenter: Stephen Swartz (Business Development Specialist, Shimadzu Scientific Instruments)Steve has been involved with the pharmaceutical industry for over 33 years. As a medicinal chemist at DuPont, Bayer, and Bristol Myers Squibb, he worked in multiple therapeutic areas supporting early phase discovery. After leaving the lab, Steve worked for several instrumentation companies in scientific support, sales, and business development. Since joining Shimadzu in 2020 as Business Development Specialist, he has worked with customers in the pharma and biopharma markets using his experience to help optimize workflows from early discovery to IND and beyond.Presenter: Kevin Wons (Market Manager - Pharma/BioPharma, Shimadzu Scientific Instruments)Kevin has recently joined Shimadzu as Market Manager for Pharma/BioPharma. He has spent the last 6 years at AstraZeneca in the Analytical Sciences Department for product and process characterization for biologics in the AstraZeneca pipeline. Kevin has applications experience with HPLC and LC-MS to do Tryptic Peptide Mapping, Intact Mass Analysis, Subunit Mass Analysis, and Oligosaccharide Profiling. For his last 3 years, he acted as the Glycan Subject Matter Expert (SME) while at AstraZeneca. His work experience also includes Maryland Psychiatric Research Center, where he prepared animal tissue samples such as Brain, Liver, Blood, and Placenta to measure kynurenine pathway metabolites on GC/MS and HPLC. He has a Master’s degree in Professional Studies (MPS) focused on Biotechnology which prepares science professionals to fill management and leadership roles.</blockquote>

Shimadzu Corporation: Chromatography Unleashed: Elevate Your Chiral and Achiral Separations

Chromatography Unleashed: Elevate Your Chiral and Achiral Separations

Join us as we show off Shimadzu’s sophisticated set of environmentally friendly solutions geared toward efficient separation of chiral and achiral molecules

Elevate Your Chiral and Achiral Separations

Protein-based therapeutics such as monoclonal antibodies are widely developed and used by the biopharmaceutical industry; in 2023, mAb-based therapeutics represented over half of the Top Ten best-selling drugs of the year, globally, and are one of the fastest growing modalities. However, these large molecules pose unique challenges in relation to sample preparation and analytical characterisation, making robust and fit-for-purpose methods essential to achieve high quality results.This December, we invite you to connect with fellow scientists to learn more about the latest innovations in Protein analysis at our ProteinConnect Virtual Forum. Through a selection of complementary presentations and resources, our specialists will share insights into the present and future of protein characterisation, including:<ul><li>How workflow solutions can address mAb CQA analysis</li><li>Hints and tips for optimising protein bioseparations</li><li>The latest tools and technologies to enhance your protein analysis</li><li>Novel approaches to support online analysis and production of mAbs</li><li>A look to the future – emerging trends in Biopharma analysis</li><li>And much more! agilent ms</li></ul><h5>Agenda 11 December 2024</h5>10:30 a.m. Elevate Your Protein Sample Preparation With The Automated AssayMAPBravo Platform11:00 a.m. Upgrade Your Protein Characterization Game With Agilent ExD11:30 a.m. Streamlining N-Glycan Analysis With A Complete Workflow From Agilent12:15 p.m. Accelerating Biopharma Workflows With Molecular Spectroscopy13:00 p.m. Looking At The Future: Approaching The Analysis Of Next-Generation Protein Therapeutic

Agilent Technologies: ProteinConnect: Linking Science, Innovation and Therapeutics

ProteinConnect: Linking Science, Innovation and Therapeutics (Day 2)

We invite you to connect with fellow scientists to learn more about the latest innovations in Protein analysis at our ProteinConnect Virtual Forum.

ProteinConnect: Linking Science, Innovation and Therapeutics

EPA Method 1634 is a draft method introduced by the U.S. Environmental Protection Agency (EPA) to detect 6PPD-quinone (6PPD-Q) in water sources, particularly stormwater and surface water. 6PPD-Q, a by-product of 6PPD (a chemical additive in tires used to prevent rubber degradation), was linked to the mass deaths of salmon population streams in the Pacific Northwest. As vehicle tire particles break down, 6PPD interacts with ozone, forming the harmful 6PPD-Q compound, which subsequently washes into aquatic ecosystems through rainwater runoff.The method uses liquid chromatography-tandem mass spectrometry (LC-MS/MS) for accurate 6PPD-Q measurement, providing customers with a crucial tool for monitoring water quality and protecting sensitive fish species and aquatic life. Although still in draft form, EPA Method 1634 supports ongoing research efforts aimed at understanding and mitigating the environmental impacts of 6PPD-Q contamination.<ul><li>Learn how to easily implement EPA Method 1634 draft, analysis of PPD-Q</li><li>Achieve Method limit of 1 ng/L</li><li>Learn Tips and Tricks for troubleshooting your assay.</li></ul>

Restec Corporation: From Tires to Toxins: Optimizing your SPE & HPLC for EPA’s Draft Method 1634

From Tires to Toxins: Optimizing your SPE & HPLC for EPA’s Draft Method 1634

EPA Method 1634 uses LC-MS/MS for accurate 6PPD-Q measurement, providing customers with a crucial tool for monitoring water quality.

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