<p><strong>V týdnu od 27. dubna na Vás čekají v oblasti kapalné fáze a především HPLC a LC/MS následující webináře.</strong></p><blockquote><h4><a target="_blank" rel="noopener noreferrer" href="https://www.lcms.cz/webinars"><strong>👉 DETAILY A REGISTRACE V SEKCI WEBINÁŘE</strong></a></h4></blockquote><blockquote><p><strong>👉 Vyhledávejte a filtrujte v největší globální databázi</strong> s více než <strong>5 500 GC, HPLC, MS a spektroskopickými webináři.</strong></p></blockquote><h5><span><strong>1. Separation Science: Analytical Excellence Week 2026: Part 1- Understanding Pharmacopoeia and ACS Compliance</strong></span></h5><ul><li>Út, 28.4.2026 09:00 CEST</li><li><a target="_blank" rel="noopener noreferrer" href="https://lcms.cz/webinar/6130">Registrace</a></li></ul><p>Zjistěte, jak zajistit shodu s farmakopeí a ACS normami a jaký vliv mají správně zvolené reagencie na kvalitu analytických výsledků.</p><h5><span><strong>2. Agilent Technologies: PFAS &amp; Our Planet: Environmental Monitoring</strong></span></h5><ul><li>Út, 28.4.2026 11:00 CEST</li><li><a target="_blank" rel="noopener noreferrer" href="https://lcms.cz/webinar/6140">Registrace</a></li></ul><p>Přehled regulací PFAS a LC-MS/MS workflow pro jejich stanovení ve vodě, půdě i ovzduší.</p><h5><span><strong>3. Restek Corporation: Air Sampling Media Selection and Analysis</strong></span></h5><ul><li>Út, 28.4.2026 14:30 CEST</li><li><a target="_blank" rel="noopener noreferrer" href="https://lcms.cz/webinar/6160">Registrace</a></li></ul><p>Jak vybrat správná sorpční média a optimalizovat odběr vzorků vzduchu pro spolehlivou analýzu.</p><h5><span><strong>4. Tosoh Bioscience: Tosoh Tuesday - What is MALS &amp; When is it Useful?</strong></span></h5><ul><li>Út, 28.4.2026 15:00 CEST</li><li><a target="_blank" rel="noopener noreferrer" href="https://lcms.cz/webinar/6145">Registrace</a></li></ul><p>Základy MALS detekce a její využití v SEC-MALS pro charakterizaci polymerů a biomolekul.</p><h5><span><strong>5. Technology Networks: Mass Spectrometry in Drug Discovery: Covalent and Non-Covalent Screening Applications</strong></span></h5><ul><li>Út, 28.4.2026 17:00 CEST</li><li><a target="_blank" rel="noopener noreferrer" href="https://lcms.cz/webinar/6114">Registrace</a></li></ul><p>MS strategie pro screening vazebných interakcí v rané fázi vývoje léčiv.</p><h5><span><strong>6. Thermo Fisher Scientific: From Sample to Structure: Crosslinking MS Made Practical - Part 1</strong></span></h5><ul><li>Út, 28.4.2026 17:00 CEST</li><li><a target="_blank" rel="noopener noreferrer" href="https://lcms.cz/webinar/6115">Registrace</a></li></ul><p>Úvod do XL-MS pro mapování proteinových interakcí a strukturálních vztahů.</p><h5><span><strong>7. SelectScience: Why researchers turn to reversed phase chromatography when purifying GLP-1</strong></span></h5><ul><li>Út, 28.4.2026 17:00 CEST</li><li><a target="_blank" rel="noopener noreferrer" href="https://lcms.cz/webinar/6117">Registrace</a></li></ul><p>Význam RP chromatografie při čištění GLP-1 peptidů v biofarmaceutickém vývoji.</p><h5><span><strong>8. Phenomenex: Fundamentals First Bio Series – SEC for Biologics</strong></span></h5><ul><li>St, 29.4.2026 10:00 CEST</li><li><a target="_blank" rel="noopener noreferrer" href="https://lcms.cz/webinar/6149">Registrace</a></li></ul><p>Základy SEC pro biologika včetně výběru kolon a řešení problémů v praxi.</p><h5><span><strong>9. SCIEX: Extending the power of LC-MS/MS: advanced workflows with QTRAP®</strong></span></h5><ul><li>St, 29.4.2026 10:00 CEST</li><li><a target="_blank" rel="noopener noreferrer" href="https://lcms.cz/webinar/6147">Registrace</a></li></ul><p>Pokročilé LC-MS/MS workflow s QTRAP® a MS³ pro vyšší citlivost a selektivitu.</p><h5><span><strong>10. ANAMET: Současná legislativa pro stanovení PFAS</strong></span></h5><ul><li>St, 29.4.2026 10:00 CEST</li><li><a target="_blank" rel="noopener noreferrer" href="https://lcms.cz/webinar/6122">Registrace</a></li></ul><p>Přehled aktuálních evropských požadavků na PFAS a jejich analytické stanovení.</p><h5><span><strong>11. Metrohm: The Basics of Titration explained</strong></span></h5><ul><li>St, 29.4.2026 15:00 CEST</li><li><a target="_blank" rel="noopener noreferrer" href="https://lcms.cz/webinar/6129">Registrace</a></li></ul><p>Základní principy titrace a jejich praktické využití v laboratorní praxi.</p><h5><span><strong>12. Separation Science: Analytical Excellence Week 2026: Part 2 - Benefits of PFAS-Tested Consumables</strong></span></h5><ul><li>Čt, 30.4.2026 09:00 CEST</li><li><a target="_blank" rel="noopener noreferrer" href="https://lcms.cz/webinar/6131">Registrace</a></li></ul><p>Význam spotřebního materiálu testovaného na PFAS pro spolehlivou analýzu.</p><h5><span><strong>13. Evosep Biosystems: Next-Gen HCP Analysis in Biopharma</strong></span></h5><ul><li>Čt, 30.4.2026 16:00 CEST</li><li><a target="_blank" rel="noopener noreferrer" href="https://lcms.cz/webinar/6151">Registrace</a></li></ul><p>Moderní LC-MS přístupy pro analýzu host cell proteins s vysokou propustností.</p><h5><span><strong>14. Bruker: Bridging Molecules and Genes: Integrating MALDI Imaging and Spatial Transcriptomics on a Single Tissue Section</strong></span></h5><ul><li>Čt, 30.4.2026 16:00 CEST</li><li><a target="_blank" rel="noopener noreferrer" href="https://lcms.cz/webinar/6132">Registrace</a></li></ul><p>Multimodální analýza tkání kombinující MALDI imaging a prostorovou transkriptomiku.</p><h5><span><strong>15. Thermo Fisher Scientific: From Sample to Structure: Crosslinking MS Made Practical - Part 2</strong></span></h5><ul><li>Čt, 30.4.2026 17:00 CEST</li><li><a target="_blank" rel="noopener noreferrer" href="https://lcms.cz/webinar/6116">Registrace</a></li></ul><p>Pokročilé aplikace XL-MS pro detailní studium biomolekulárních interakcí.</p>

Webináře LabRulezLCMS týden 18/2026

<p><strong>Zajištění souladu s metodami iontové chromatografie (IC), jako jsou US EPA 300.1 části A a B, ISO 10304 části 1 a 4 nebo US EPA 557, představuje při monitorování environmentálních vod významnou výzvu. Klíčovým faktorem je správná volba kolony – ať už pracujete s uhličitanovými nebo hydroxidovými eluenty.</strong></p><ul><li>📆7. května 2026</li><li><span style="color:rgb(51,51,51);font-family:&quot;Helvetica Neue&quot;, Helvetica, Arial, 微軟正黑體, 微软雅黑, メイリオ, &quot;맑은 고딕&quot;, sans-serif;font-size:14px;"><span style="font-style:normal;font-weight:400;letter-spacing:normal;text-align:start;text-indent:0px;text-transform:none;">🕒</span></span>od 15:00 hodin</li><li><strong>Délka trvání: </strong>1 hodina</li></ul><blockquote><p class="cke-user_style-important"><a target="_blank" rel="noopener noreferrer" href="https://event.eu.on24.com/wcc/r/8000194381/D149BCA4121F2AAC7C7AEB2450D19207"><strong>Registrace na webinář</strong></a></p></blockquote><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/metrohm_webinar_IC_columns_fa2617c84f.jpg" alt="Metrohm: Nová generace vysokokapacitních IC kolon pro analýzu vzorků životního prostředí" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_metrohm_webinar_IC_columns_fa2617c84f.jpg 245w," sizes="100vw" width="650" height="300"></p><p>V tomto webináři se zaměříme na novou generaci vysokokapacitních kolon pro aniontovou výměnu. Ukážeme, jak inovativní chemie kolon umožňuje dosahovat velmi nízkých detekčních limitů a zároveň zvyšuje robustnost analýzy i u komplexních matric, což je zásadní pro plně vyhovující analýzu environmentálních vod.</p><p>Představíme dvě komplementární analytické strategie pro stanovení běžných <strong>aniontů a oxyhalogenidů</strong>: přístup s uhličitanovým eluentem využívající novou kolonu <strong>Metrosep A Supp 20 </strong>a hydroxidově selektivní přístup s kolonou <a target="_blank" rel="noopener noreferrer" href="https://lcms.cz/products/2114"><strong>Metrosep A Supp 21</strong></a>. Obě strategie umožňují provádět metody <strong>US EPA 300.1</strong> (části A a B) a <strong>ISO 10304</strong> (části 1 a 4) <strong>v rámci jedné analýzy.</strong></p><p>Součástí webináře bude také <strong>ukázka automatické generace hydroxidového eluentu</strong>, která zajišťuje vysoce přesné a reprodukovatelné výsledky s extrémně nízkou základní linií. Tento přístup je ideální i pro náročné aplikace, jako je stanovení halooctových kyselin (<strong>HAA</strong>) podle US EPA 557.</p><h4><span><strong>Co se v tomto webináři naučíte</strong></span></h4><ul><li>Jak vysokokapacitní IC kolony zlepšují robustnost, přesnost a reprodukovatelnost analýzy environmentálních vod</li><li>Jak provádět metody EPA 300.1 (A, B) a ISO 10304 (1, 4) v jedné analýze</li><li>Výhody automatické generace eluentu v kombinaci s hydroxidově selektivními kolonami (např. <a target="_blank" rel="noopener noreferrer" href="https://lcms.cz/products/2112"><strong>Metrosep A Supp 19</strong></a>)</li><li>Jak optimalizovat pracovní postupy a zvýšit efektivitu i kvalitu dat</li></ul><h4><span><strong>Pro koho je webinář určen</strong></span></h4><ul><li>Provozovatele vodárenských a vodohospodářských laboratoří</li><li>Vedoucí laboratoří odpovědné za legislativní shodu analýz</li><li>Vědce, výzkumníky a vývojáře analytických metod v oblasti IC</li><li>Laboratorní pracovníky hledající spolehlivé a efektivní řešení pro monitoring vod</li></ul><blockquote><h5><span><strong>Přednášející</strong></span></h5><p><strong>Dr. Vincent Diederich </strong>(Product Manager Ion Chromatography Columns, Metrohm International Headquarters)</p><p>Vincent Diederich vystudoval chemické a bioinženýrství na ETH Zürich, kde následně získal titul Ph.D. v oboru chemického inženýrství. Od roku 2015 působí ve společnosti Metrohm, kde se věnuje vývoji kolon a metod pro iontovou chromatografii. V současnosti zastává pozici produktového manažera pro IC kolony.</p></blockquote>

Nová generace vysokokapacitních IC kolon pro analýzu vzorků životního prostředí

<p><strong>Vážení zákazníci a příznivci laboratorní techniky,</strong></p><p>rádi bychom Vás pozvali na <strong>výjimečnou událost DISCOVERY DAYS 2026</strong>, která letos proběhne opět v novém a intenzivnějším formátu.</p><p><strong>Kulatý stůl</strong>, který byl loni novou součástí programu, jsme nově <strong>rozšířili do tří bloků</strong>. Každý z nich jsme navíc mírně prodloužili, abyste měli více prostoru pro hlubší diskusi a sdílení zkušeností.</p><p>Vyberte si oblast, která vás zajímá, a můžete se buď aktivně zapojit do diskuze, nebo si jen v klidu vyslechnout zkušenosti ostatních kolegů.</p><p>Žádný stres – jen otevřená a přátelská výměna názorů a tipů z praxe.</p><h5><strong>Kdy a kde se letos Discovery Days konají?</strong></h5><ul><li><strong>16. 6. 2026</strong> - Grandior Hotel Prague&nbsp;</li><li><strong>17. 6. 2026</strong> - Clarion Congress hotel Brno</li></ul><h3><strong>Registrace</strong></h3><blockquote><p class="cke-user_style-important">👉 <a target="_blank" rel="noopener noreferrer" href="https://forms.office.com/Pages/ResponsePage.aspx?id=aR-wpy9pT0iMxW5H7RJK8WO2jiQLb7NOszjVkgYyezJUQkE5SDE3VDFKSDVYWUUyQzBGUkFKSThYQy4u"><strong>Registrace</strong> <strong>Praha</strong></a></p><p class="cke-user_style-important">👉<a target="_blank" rel="noopener noreferrer" href="https://forms.office.com/Pages/ResponsePage.aspx?id=aR-wpy9pT0iMxW5H7RJK8WO2jiQLb7NOszjVkgYyezJUNjJQTEI3OUQzNkI3NElVR0daT1FOOVFVQi4u"><strong>Registrace Brno</strong></a></p><p>Z důvodu omezené kapacity si prosím rezervujte své místo <strong>nejpozději do 2. 6. 2026</strong>.</p><p><strong>Akce je zdarma a bude probíhat v českém jazyce.</strong></p></blockquote><h5><strong>Těšit se můžete na:</strong></h5><ul><li>novinky v oblasti laboratorních zařízení</li><li>kulaté stoly - témata, která vás zajímají</li><li>ukázky špičkových přístrojů</li><li>technické konzultace</li><li>bohaté občerstvení</li></ul><h3><strong>PROGRAM</strong></h3><h5><strong>08:15 - 09:00 Registrace a welcome coffee</strong></h5><h5><strong>09:00 - 09:05 Zahájení</strong></h5><h5><strong>09:05 - 09:30 Představení novinek</strong></h5><ul><li>Lukáš Plaček, Karel Voldřich</li></ul><h5><strong>09:30 - 10:20 Workshopy u kulatých stolů 1. část</strong></h5><h5><strong>10:20 - 11:00 Coffee break</strong></h5><h5><strong>11:00 - 11:50 Workshopy u kulatých stolů 2. část</strong></h5><h5><strong>12:00 - 12:50 Workshopy u kulatých stolů 3. část</strong></h5><h5><strong>13:00 Oběd</strong></h5><h4><strong>Workshopy u kulatých stolů</strong></h4><h5><strong>STŮL 1 Hmotnostní spektrometrie 2026: Rozbor nejnovějších technologií vysokého rozlišení Thermo Fisher Scientific</strong></h5><ul><li>Roman Hájek, Petr Šulc</li></ul><h5><strong>STŮL 2 Iontová chromatografie v nové legislativě: PFAS – F, chlorečnany, polární pesticidy a další aplikace</strong></h5><ul><li>Magdalena Voldřichová, Aleš Hrádek, Radim Kruliš</li></ul><h5><strong>STŮL 3 Plynová chromatografie a GC-MS pod lupou: Od rutinních analýz k vysokému rozlišení</strong></h5><ul><li>Jaroslav Novák, Kateřina Sklenářová, Martin Tyleček</li></ul><h5><strong>STŮL 4 Kam kráčí HPLC: Klíčové směry vývoje kapalinové chromatografie v roce 2026</strong></h5><ul><li>Zuzana Snížková, Martin Mičic/ Michal Žalud</li></ul><h5><strong>STŮL 5 Nekompromisní kvantifikace: Maximální výkon trojitých kvadrupólů a pastí Thermo Scientific</strong></h5><ul><li>František Zaleš, Petra Dinisová,</li><li>Štěpán Vojáček/ Jiří Maleček</li></ul><h5><strong>STŮL 6 Vše, co není vidět pouhým okem</strong></h5><ul><li>Štěpán-Adam Havlíček</li></ul><h5><strong>STŮL 7</strong></h5><h5><strong>1. ČÁST + 3. ČÁST: Když se rozhoří plazma a prvky začnou mluvit – svět ICP-OES a prvkové analýzy</strong></h5><h5><strong>2. ČÁST: ICP-MS bez zbytečných odstávek – inovativní přístup k údržbě</strong></h5><ul><li>Matouš Humplík</li></ul><h5><strong>STŮL 8 Prvková analýza na mokré i suché cestě</strong></h5><ul><li>Jaroslav Kolejka</li></ul><h5><strong>STŮL 9 Příprava vzorku, extrakce/ homogenizace, centrifugace a lyofilizace</strong></h5><ul><li>Jiří Meindl, Richard Bursa</li></ul><blockquote><p>V případě jakýchkoli dotazů kontaktujte prosím <strong>Andreu Zuzánkovou</strong>: <a href="mailto:zuzankova@pragolab.cz"><strong>zuzankova@pragolab.cz</strong></a><strong> </strong>/ <strong>+420 778 960 580</strong></p></blockquote><p>Těšíme se na setkání s Vámi.</p><p><strong>Tým Pragolab s.r.o.</strong></p>

Pragolab DISCOVERY DAYS 2026 (registrace a program)

Webináře

Životní prostředí

Vody

Článek

Produkt

Video

Nejbližší akce

Naše společnost nabízí řešení v oblasti iontové analýzy pomocí titrace, iontové chromatografie, voltametrie a polarografie.

Metrohm Česká republika

Vše ze světa analytické chemie na jednom místě. Propojujeme lidi při řešení jejich problémů. U nás naleznete všechny potřebné informace snadno, rychle a přehledně. Přestaňte hledat a začněte nacházet.

LabRulez

Jsme jedním z lídrů na českém a slovenském trhu v oblasti laboratorních zařízení a svým zákazníkům přinášíme špičkové přístroje z oboru analytické chemie a fyzikálních měření více než 25 let.

Pragolab

Metrohm

Agilent Technologies

Thermo Fisher Scientific

Shimadzu Corporation

Evosep Biosystems

Waters Corporation

<p><strong>The upcoming webinar will delve into the latest advancements in pneumococcal polysaccharide vaccines and pneumococcal conjugate vaccines (PCVs), focusing on their development, production, and quality control. Key topics include the introduction of a new USP general chapter for the SEC-MALS method, the challenges of serotype replacement, and the evolution of PCVs to include more serotypes.</strong></p><p>The session will explore the critical role of SEC-MALS in ensuring vaccine consistency and stability, highlighting its advantages over traditional analytical techniques, as well as the benefits of FFF-MALS for ultra-high molecular weight PCV analysis.</p><p><strong>Key Learning Objectives:</strong></p><ul><li><strong>Understanding Pneumococcal Vaccines</strong>: Gain insights into the differences between pneumococcal polysaccharide vaccines and PCVs, their historical development, and their impact on public health.</li><li><strong>Challenges in Vaccine Development:</strong> Learn about serotype replacement and the on-going efforts to develop vaccines that cover a broader range of serotypes.</li><li><strong>Analytical Techniques:</strong> Explore the advantages of using SEC-MALS for multi-attribute quantification of vaccines, including its role in process development and quality control.</li><li><strong>Future Directions: </strong>Discover the latest advancements in PCV development, including the push towards 30+ valent vaccines and the role of emerging technologies in vaccine production.</li></ul><p><strong>Who Should Attend:</strong></p><ul><li><strong>Vaccine Researchers:</strong> Researchers involved in vaccine development will benefit from understanding the latest advancements in pneumococcal vaccines and the analytical techniques used to ensure their efficacy and safety.</li><li><strong>Quality Control Specialists: </strong>Professionals responsible for the quality control of vaccines will gain valuable insights into the use of SEC-MALS for monitoring vaccine consistency and stability.</li><li><strong>Pharmaceutical Manufacturers:</strong> Individuals working in the production and development of vaccines will find the discussion on new analytical methods and the challenges of serotype replacement crucial for improving vaccine formulations.</li></ul><blockquote><p><strong>Presenter: </strong>Katayoun Morakabi, Ph.D. (Application Scientist)</p><p>Katayoun Morakabi (Kat) is an application scientist on the Analytical Sciences team at Wyatt Technology, a portfolio of Waters corporation. Kat assists customers in identifying the best light scattering solutions for their analytical needs by performing feasibility studies and leveraging her expertise in multi-angle light scattering. She earned her Ph.D. in Biochemistry from the University of Texas at Dallas, where her doctoral research focused on characterizing the structure, dynamics, and functional outcomes of proteins. If you attend Light Scattering University at Wyatt's headquarters in Santa Barbara, you might meet Kat in person as one of your instructors.</p></blockquote>

Waters Corporation: Advances in Polyconjugate Vaccine Development: Leveraging SEC-MALS for Enhanced Quality Control and Efficacy

Advances in Polyconjugate Vaccine Development: Leveraging SEC-MALS for Enhanced Quality Control and Efficacy

This webinar explores advances in pneumococcal vaccines, focusing on development, production, and quality control.

Polyconjugate Vaccines: SEC-MALS for Quality & Efficacy

<p><strong>Drug discovery is the process through which potential new medicines are identified. It involves a wide range of scientific disciplines, including biology, chemistry and pharmacology.</strong></p><p>The complexity in drug development has increased manifolds over the past 40 years, requiring preclinical testing, investigational new drug applications, and completed clinical testing before marketing approval from the FDA.</p><p>Generally, new drug applications or biologics license applications are reviewed comprehensively before approval, and then drug performance is resubmitted to regulatory agencies for post-marketing studies. The overarching goal is to bring more efficient and safer treatments to the patients as quickly as possible after a thorough medical evaluation.</p><p>In this webinar we will look into how the Evosep One with high-throughput and sensitivity is a good fit when developing new drug applications or biologics license applications.&nbsp;</p><blockquote><p><strong>Presenter: TBA soon</strong></p></blockquote>

Evosep Biosystems: Accelerating Drug Discovery with high-throughput proteomics

Accelerating Drug Discovery with high-throughput proteomics

In webinar we will look into how Evosep One with high-throughput and sensitivity is good for developing drug applications or biologics license applications

<p><strong>Drug discovery has advanced into a highly complex and regulated process, requiring the seamless integration of biology, chemistry, and pharmacology. Over the past decades, the increasing demand for preclinical validation, clinical trials, and regulatory approvals has emphasized the need for more efficient analytical workflows.</strong></p><p>To accelerate innovation while maintaining data quality, high-throughput and robust analytical methods are essential. In this webinar, we explore how Evosep One is shaping industrialized drug discovery by enabling higher sensitivity, reproducibility, and scalability—critical factors in developing new drug applications and biologics license applications.</p><p>Join us to learn how industrialized proteomics can enhance drug discovery pipelines, reduce bottlenecks, and bring safer treatments to patients faster.</p><h4><strong>Proteomics Empowering Drug Discovery &amp; Translational Research – “Are We There Yet?”</strong></h4><p><strong>Presenter: </strong>Ashok Dongre (Senior Director &amp; Head of Proteomics at Bristol-Myers Squibb)</p><p>Proteomics has evolved over the past 25+ years, experiencing a recent renaissance with the adoption of various transformative methodologies, including mass spectrometry and reagent-based profiling approaches. While proteomics has made significant progress, it still faces barriers to widespread adoption in biological and biopharma research. This presentation aims to showcase how advancements in next-gen LC-MS technology and deep learning data analytics can provide actionable insights for drug discovery and translational research. By addressing complex questions at the intersection of disease pathophysiology and biopharma research, proteomics can have a profound impact. This marks the beginning of what is possible with proteomics, as Winston Churchill said, “…it is perhaps the end of the beginning.”</p><h4><strong>Decoding PPIs: Insights from APMS and Convergent Network Biology</strong></h4><p><strong>Presenter:</strong> Chris Adams, Director of Proteomics at Rezo Therapeutics</p><p>Understanding drug action at the molecular level requires a comprehensive view of protein-protein interaction (PPI) networks. In this talk, I will present our approach to elucidating novel drug targets using network analysis and affinity purification mass spectrometry (AP-MS). By investigating differential PPI networks in response to drug treatment, we identify key regulatory hubs and pathway alterations. This integrative strategy enhances our ability to uncover mechanistic insights and guide rational drug development.</p>

Evosep Biosystems: Industrialized Drug Discovery with the Evosep One

Industrialized Drug Discovery with the Evosep One

In this webinar, we explore how Evosep One is shaping industrialized drug discovery by enabling higher sensitivity, reproducibility, and scalability

<p><strong>Column selection for SEC/GPC is a key challenge in biomolecular seperations. Understanding when to choose what type of column is critical for developing successful SEC/GPC methods.</strong></p><p>In this webinar, we will highlight the main factors that define a strong SEC column and illustrate how they benefit the analysis of different modalities, including AAVs, VLPs, and large oligonucleotides.</p><h5><strong>Key learning objectives</strong></h5><ul><li>Learn how to choose the right SEC/GPC column for biomolecular analysis.</li><li>Discover key factors: particle size, pore volume, detector compatibility, and more.</li><li>Explore workflow examples for better understanding.</li></ul><h5><strong>Who should attend?</strong></h5><ul><li>Analytical chemists focusing on SEC/GPC for biomolecules, including AAVs, VLPs, and large oligonucleotides.</li></ul><blockquote><p><strong>Presenter: </strong>Katrien Sabbe, PhD (Biopharma Business Development Manager Chemistries and Supplies, Agilent Technologies)</p><p>Katrien Sabbe holds a PhD in organic synthesis (Ghent University, Belgium). For more than 25 years she is working in the field of Chromatography Columns and Supplies, first at VWR International and later at Varian Analytical Instruments, which was acquired in 2011 by Agilent Technologies. Currently she is the EMEA Biopharma Business Development Manager at Agilent Technologies Chemistries and Supplies Division.</p></blockquote>

Agilent Technologies: Advanced Column Selection for SEC/GPC Analysis of Biomolecules

Advanced Column Selection for SEC/GPC Analysis of Biomolecules

In this webinar, we will highlight the main factors that define a strong SEC column

Column Selection for SEC/GPC Analysis of Biomolecules

<p><strong>Preparative chromatography has been an integral component of pharmaceutical discovery and development for the past fifty plus years. The past thirty-five years have seen great advances in small molecule purification. Purification techniques have advanced from those centered around large irregular particles operating under low pressure to more efficient high-performance technologies utilizing small spherical particles. Technologies now routinely used include preparative HPLC, SMB, and SFC. At the discovery scale, these advances allow routine and rapid chiral and achiral purification of the large numbers of molecules synthesized at this stage of pharmaceutical R&amp;D. For pharmaceutical development these advances allow chromatographic purifications using HPLC and SMB to be a standard tool in the process development toolbox. The large number of pharmaceutical chiral SMB operations at the manufacturing scale has shown that chromatography can be a cost-effective alternative to asymmetric synthesis or other resolution techniques.</strong></p><p>This presentation will discuss the critical role small molecule purification plays within a pharmaceutical company. Multiple real-life examples from ug to metric ton scale supporting Discovery through Manufacturing activities will be presented. In addition, the importance of personnel, facility, automation, and information systems for a successfully integrated purification platform will be discussed.</p><blockquote><p><strong>Presenter: </strong>Larry Miller (Associate Director, Novartis)</p><p>Larry Miller is an Associate Director in the Global Discovery Chemistry Group at Novartis in Cambridge, MA responsible for analytical and purification support for Discovery. He has spent his career performing small molecule achiral and chiral purifications at the mg to multi-kg scale using a variety of chromatographic techniques. Larry has over 40 peer-reviewed publications and over 45 presentations at scientific meetings. He also co-authored “Modern Supercritical Fluid Chromatography: Carbon Dioxide Containing Mobile Phases” with David Pinkston and Larry Taylor. Larry also serves as co-instructor for an SFC short course which has been held at numerous chromatography conferences in the United States, Europe, and Asia over the past fifteen years. In addition, Larry is the current president of the Green Chemistry Group, a not-for-profit group that organizes the annual SFC conference.</p></blockquote>

Agilent Technologies: Small Molecule Chromatographic Purification in Pharmaceutical R&D and Manufacturing

Small Molecule Chromatographic Purification in Pharmaceutical R&D and Manufacturing

This presentation will discuss the critical role small molecule purification plays within a pharmaceutical company.

Small Molecule Purification in Pharma R&D and Manufacturing

<div><div><p><strong>High-resolution mass spectrometry (HRMS) has become the technique of choice for screening applications in forensic and doping laboratories. The Forensic Toxicology Screening Application Solution from Waters was first released in 2015 and has continued to evolve over the years; the current system comprises an ACQUITY UPLC I-Class and Xevo G3 QTof Mass Spectrometer together with a dedicated application package for forensic toxicology and brings the power of high resolution and accurate mass data to the routine laboratory.</strong></p><p>The current solution is powered by an application-based software package, waters_connect which provides a single platform for LC and LC-MS applications that accelerates end-to-end scientific workflows, realizing new standards of usability, scientific outcome and compliance.</p><p>In addition to the current solution with the Xevo G3 QTof, Waters have recently launched the Xevo MRT, an ultra-high resolution mass spectrometer, achieving mass resolution of up to 100K and mass accuracies typically less than 500 parts-per-billion. With the introduction of this new technology into the forensic and toxicology arena, it has the capabilities to change the way we view mass accuracy for targeted analysis, providing even more assurance when reporting results, but also the extra confidence when performing discovery type analysis, in search of novel psychoactive substances.</p><h4><strong>Key learning objectives:</strong></h4><ul><li>Learn about the development and advancement of the Waters Forensic Screening Application Solution.</li><li>Recognize the benefits of using a single platform for improved usability, scientific outcomes and compliance.</li><li>Assess the significance of Xevo MRT’s ultra-high resolution and mass accuracy in forensic and toxicology applications.</li></ul><p><i>For Forensic Toxicology Use only.</i></p><blockquote><p><strong>Presenter: </strong>Nayan Mistry (Senior Clinical Application Scientist, Forensic Toxicology, Research &amp; Development, Waters Corporation)</p><p>Nayan Mistry is a Senior Application Scientist at Waters Corporation. Nayan joined Waters in 2009 and is part of a global team dedicated to performing research and development of applications and analytical solutions for Forensic Toxicology.</p><p>Nayan’s key focus is on toxicology screening and he has expertise with both nominal mass and accurate mass-based screening using UNIFI and Waters_Connect application software. Nayan plays a key role in the development of these solutions and in the expansion of associated libraries. Currently Nayan is playing a key role in the development and support of the recently launched Xevo G3 QTof mass spectrometer in addition to other responsibilities for the nominal mass applications. His favourite aspect of the role is customer support - Nayan is greatly involved in global on-site customer support and training and has presented his work at conferences worldwide.</p></blockquote></div></div>

Waters Corporation: Revolutionizing High Resolution Mass Spectrometry and Forensic Toxicology: Key Updates and Solutions

Revolutionizing High Resolution Mass Spectrometry and Forensic Toxicology: Key Updates and Solutions

Learn about the development and advancement of the Waters Forensic Screening Application Solution

Revolutionizing HRMS and Forensic Toxicology

<div><div id="inner_content_body_text" data-content-id="394785"><p><strong>Single-cell analysis is a new and rapidly growing field that is shedding new insight into the cellular mechanisms behind the pathogenesis and treatment of infectious diseases and cancer. Cells, even within a single tissue, culture or biological fluid are highly heterogenous. Analysis of bulk material therefore only provides an average value, meaning that information is lost. Single cell transcriptomics and proteomics are already making major advances to understand infection, immunity and drug delivery. Single cell lipidomics and metabolomics are highly desirable to understand the endpoint of metabolism, but currently lag behind the other “omics” at single cell level. Similarly, sub-cellular analysis is highly desirable to understand cellular rearrangement in response to stressors such as pathogens and radiation.</strong><br><br>The SEISMIC facility for spatially resolved single and sub-cellular “omics” is a new multi-user facility, that aims to advance single cell and sub-cellular measurements, together with and for the benefit of bioscientists across the UK. At SESIMC, we use capillary sampling to sample live cells or sub-cellular compartments under microscope observation. This method of sample capture can be coupled to chromatographic separation, which offers additional advantages in mitigating matrix effects and aiding peak assignment. We will show how live single-cell lipidomics can be achieved using capillary-sampled cells as well as microfluidics. We will show the expected performance from state-of-the-art mass spectrometry systems. We will also show how these technologies can be applied to reveal how single cell lipid profiles of cancer cells respond to drug and radiation treatment. We will further report on progress towards sub-cellular sampling and mass spectrometry metallomics and proteomics analysis</p><p><strong>Learning Objectives:</strong></p><ul><li>How does the SEISMIC facility enable spatially resolved single-cell and sub-cellular 'omics' analysis?</li><li>How can single-cell lipidomics be applied to study cellular responses to drug and radiation treatments in cancer cells?</li></ul><p><br><i>Webinars will be available for unlimited on-demand viewing after live event.</i></p><blockquote><p><strong>Presenter:</strong> Melanie Bailey, PhD (Professor, University of Surrey)</p><p>Melanie Bailey is Professor of Analytical Science at the University of Surrey. She is Director of the Wolfson Centre of Excellence for Bioanalytical Science, which brings together expertise in “omics”, biomarker discovery and imaging. This includes SEISMIC, a new BBSRC national facility for spatially resolved single and sub-cellular “omics” , new instrumentation for multimodal imaging at the UK National Ion Beam Centre and bulk metabolomics, proteomics and metallomics. She is a member of the international advisory board for The Ion Beam Analysis conference series, International Nuclear Microprobe conference series and the Bragg Institute. She is a Trustee of the Analytical Chemistry Trust Fund and ran the London Marathon to raise money for Analytical Science in 2024. She will commence a term as Editor in Chief of the Royal Society of Chemistry’s longest running journal “Analyst” in September 2024.</p></blockquote></div></div>

Thermo Scientific: Towards sub-cellular mass spectrometry omics: The SEISMIC facility for spatially resolved single and sub-cellular omics

Towards sub-cellular mass spectrometry omics: The SEISMIC facility for spatially resolved single and sub-cellular omics

In this webinar you will learn how does the SEISMIC facility enable spatially resolved single-cell and sub-cellular 'omics' analysis.

SEISMIC facility - spatially resolved single cellular omics

<p><strong>Join us for this event that will discuss how Shimadzu SFC technology is being used to drive innovation throughout the drug development process. &nbsp;We will examine the break-through use of SFC with LabSolutions MD AQbD method development software to model and optimize peptide separations. &nbsp;</strong></p><p>The topic of Exposed Polar Surface Area analysis by SFC will be discussed and how its application to cyclic peptide therapeutics speeds up drug candidate selection. &nbsp;We will share recent developments in SFC separations for oligonucleotides, along with other enabling solutions for micro-prep SFC (analytical scale fractionation), hybrid UHPLC-SFC systems, and more.</p><p>We will host a Q&amp;A session after the presentation to address any questions or comments.</p><blockquote><p><strong>Presenter: </strong>Brian Domanski (Strategic Collaboration Scientist, Shimadzu Scientific Instruments)</p><p>Brian has over 10 years working to provide LC and SFC solutions for Pharma, as well as experience with a wide range of chromatography techniques including RP, NP, HILIC, IEX, SEC/GPC, and IC. His focus also includes scalable Informatics and Data Integrity solutions.</p><p><strong>Presenter: </strong>Kevin Wons (Market Manager - Pharma/BioPharma, Shimadzu Scientific Instruments)</p><p>Kevin has recently joined Shimadzu as Market Manager for Pharma/BioPharma. He has spent the last 6 years at AstraZeneca in the Analytical Sciences Department for product and process characterization for biologics in the AstraZeneca pipeline. Kevin has applications experience with HPLC and LC-MS to do Tryptic Peptide Mapping, Intact Mass Analysis, Subunit Mass Analysis, and Oligosaccharide Profiling. For his last 3 years, he acted as the Glycan Subject Matter Expert (SME) while at AstraZeneca. His work experience also includes Maryland Psychiatric Research Center, where he prepared animal tissue samples such as Brain, Liver, Blood, and Placenta to measure kynurenine pathway metabolites on GC/MS and HPLC. He has a Master’s degree in Professional Studies (MPS) focused on Biotechnology which prepares science professionals to fill management and leadership roles.</p></blockquote>

Shimadzu: Innovations in SFC Applications and Technology for Pharma and Biopharma

Innovations in SFC Applications and Technology for Pharma and Biopharma

Join us for this event that will discuss how Shimadzu SFC technology is being used to drive innovation throughout the drug development process. 

Innovations in SFC Applications in (Bio)Pharma 

<div id="contentLeft"><div id="realLeftContent"><div id="summary2" dir="ltr" aria-live="off"><div><div dir="" aria-atomic="true"><p><strong>Pushing ion chromatography (IC) results down to the parts-per-billion (ppb) level and beyond is challenging but achievable. Interferences from matrix components, risks of contamination, and signal suppression are common obstacles that can compromise accuracy and sensitivity. To obtain reliable results, advanced techniques are needed to isolate and concentrate target ions while minimizing errors.</strong></p><p>In this webinar, we’ll discuss best practices for trace-level analyses, including inline preconcentration strategies and methods to eliminate interfering portions of the sample matrix. These techniques enhance workflow efficiency, reduce sample preparation time, and minimize contamination risks. Real-world examples from laboratories in the nuclear energy and semiconductor manufacturing industries will highlight the successful application of these approaches.</p><h4><strong>Who should attend?</strong></h4><ul><li>IC users interested in optimizing sub-ppm level ion analyses</li><li>Lab managers and directors looking to introduce trace level analysis capabilities into their lab</li><li>Researchers that need solutions for detecting trace ions in complex matrices&nbsp;</li></ul><h4><strong>Key learning points</strong></h4><ul><li>Understand the challenges of ultra-trace ion analyses using IC</li><li>Learn about techniques and best practices to achieve the lowest detection limits</li><li>Review the fundamentals of ion chromatography</li></ul><blockquote><p><strong>Presenter: </strong>Dr. Sylvia Singh (Ion Chromatography Applications Specialist, Metrohm USA)</p><p>Dr. Sylvia Singh is the Applications Specialist for Ion Chromatography at Metrohm USA in Riverview, Florida. She earned her PhD in Chemistry with a focus on Bioorganic Chemistry at the University of South Florida (USF). At USF, Sylvia worked as a researcher and Teaching Assistant within the Chemistry Department. During her time with Metrohm USA, she continues to represent the voice of the customer, while working on application growth through lab project feasibility studies, technical and applications support, as well as product support.</p><p><strong>Presenter:&nbsp;</strong>Linx Waclaski (Product Manager Ion Chromatography, Metrohm USA)</p><p>Linx Waclaski is the Product Manager for Ion Chromatography at Metrohm USA in Riverview, Florida. He has years of experience in multiple chromatographic techniques, including ion chromatography, gas chromatography, liquid chromatography, and mass spectrometry, with extensive experience in R&amp;D and applications development. His chromatography applications experience extends across environmental, food safety, and life sciences industries. He has an M.S. in Forensic Science from Duquesne University.</p></blockquote></div></div></div></div></div>

Metrohm: Pushing the Limits: Best Practices for Ultra-trace Ion Chromatography

Pushing the Limits: Best Practices for Ultra-trace Ion Chromatography

In this webinar, we’ll discuss best practices for trace-level analyses, including inline preconcentration strategies

Best Practices for Ultra-trace Ion Chromatography

<p><strong>Whenever one makes a reflectance measurement of a sample on a substrate or a transparent sample, there is a possibility of the second surface reflection being included in the measurement.&nbsp;</strong></p><p>This inclusion into the measurement results in an inaccurate measurement of the sample. There are several ways to eliminate the second surface reflection from being measure and they will be examined in both principle and demonstration during this presentation.</p><blockquote><p><strong>Presenter: </strong>Scott Melis, PhD (Application Scientist, Agilent Technologies, Inc.)</p><p>Scott Melis has a PHD in Physics from Georgetown University in Washington, DC and started with Agilent in 2021 as a Molecular Spectroscopy Application Scientist. In his graduate work, Scott studied nanoparticle formation and growth for a variety of applications. Projects that he worked with include developing processes to deposit and characterize semiconducting molecular nano-cocrystals for use in optoelectronic devices as well as controlling polymer nanoparticle size through rapid mixing conditions.</p></blockquote>

Agilent Technologies: Optimize your FTIR, UV-Vis-NIR, Raman, Imaging, and Fluorescence Workflows

Elimination of Second Surface Reflections in a UV-Vis-nir Reflectance Measurement

Join our webinar and learn how to eliminate second surface reflections in reflectance measurements for accurate results

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Pragolab DISCOVERY DAYS 2026 (registrace a program)

Nová generace vysokokapacitních IC kolon pro analýzu vzorků životního prostředí

Webináře LabRulezLCMS týden 18/2026