<p><strong>Mulčovací fólie používané v zemědělství se postupně rozkládají a mohou se stát významným zdrojem mikroplastů v půdě. Nová studie ukazuje, že tyto částice ovlivňují nejen strukturu půdy, ale také mikrobiální život a cyklus dusíku.</strong></p><p><i>„Chtěli jsme pochopit, jak mikroplasty z konvenčních i biologicky rozložitelných mulčovacích fólií ovlivňují vlastnosti půdy, mikrobiální diverzitu a funkce, v reálných podmínkách“ </i>vysvětluje <strong>Klára Šmídová</strong>, spoluautorka studie. <i>„Proto jsme do půdy na experimentálních plochách ve Finsku, Německu a Španělsku přidali realistická množství mikroplastů, sledovali je během dvou vegetačních období a porovnávali s kontrolou.“</i></p><p>Výsledky ukázaly, že mikroplasty mění vlastnosti půdy a mikrobiální společenstva, i když ne vždy stejným způsobem. <i>„Co bylo konzistentní, je snížení mikrobiální aktivity spojené s klíčovými procesy, jako je cyklus dusíku. Tyto negativní účinky byly silnější při vyšších koncentracích mikroplastů a výrazněji se projevily ve druhém odběrovém roce,“</i> dodává Šmídová.</p><p>Protože koncentrace mikroplastů použité ve studii odpovídají množstvím nalezeným v evropských půdách, výsledky zdůrazňují reálná rizika pro zdraví půdy. <i>„Zjistili jsme také, že účinky byly významnější v jižní Evropě než v severní, pravděpodobně kvůli rozdílům v klimatu a půdních podmínkách. To znamená, že ochrana půd před plastovým znečištěním bude vyžadovat regionálně specifická hodnocení rizik,“ </i>říká Šmídová.</p><p>Více než 60 % evropských půd je považováno za nezdravé, přičemž degradace pokračuje vlivem neudržitelného využívání půdy, kontaminace, změny klimatu a extrémních povětrnostních jevů. V reakci na to <strong>přijala Evropská unie v říjnu 2025 zákon o monitorování půdy</strong>, jehož cílem je dosáhnout zdravých půd v celé Evropě<strong> do roku 2050</strong>. <i>„Zákon zdůrazňuje roli zdraví půdy pro potravinovou bezpečnost, kvalitu vody a klimatické cíle a zavádí jednotné monitorování půd ve všech členských státech. Obsahuje opatření na podporu zemědělců a lesníků, vytváří veřejný seznam potenciálně kontaminovaných lokalit a poskytuje rámec pro vznik indikativního seznamu látek vhodných pro monitorování,“ </i>vysvětluje Klára Šmídová. Studie je součástí projektu <strong>PAPILLONS</strong>, který udržoval úzký kontakt se spolutvůrci legislativy, aby podpořil jejich snahu zahrnout mikroplasty do monitorování kontaminantů půdy.</p><p>Na projektu spolupracovalo<strong> 19 výzkumných skupin po celé Evropě</strong>. <i>„Po každém vegetačním období byly odebrány stovky vzorků a zaslány partnerům k analýze. Tento článek se zaměřuje na vlastnosti půdy, mikrobiální společenstva a emise skleníkových plynů. Další dva články– o osudu mikroplastů a aditivech do nich obsažených a o půdních bezobratlých – jsou v přípravě. Společně nám poskytnou kompletní obraz o tom, jak zemědělské mikroplasty ovlivňují půdní ekosystémy,“</i> uzavírá Klára Šmídová.</p><blockquote><p><strong>Mgr. Klára Šmídová, Ph.D.</strong></p><ul><li><strong>telefon:</strong> <a href="tel:+420549493143"><span>549&nbsp;49&nbsp;<strong>3143</strong></span></a></li><li><strong>e‑mail:</strong> <a href="klara.smidova@recetox.muni.cz">klara.smidova@recetox.muni.cz</a></li></ul></blockquote><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/RECETOX_Vysledky_nove_studie_ukazaly_ze_mikroplasty_meni_vlastnosti_pudy_a_mikrobialni_spolecenstva_i_v_realnych_podminkach_6ee3413a7b.jpg" alt="RECETOX: Výsledky nové studie ukázaly, že mikroplasty mění vlastnosti půdy a mikrobiální společenstva i v reálných podmínkách" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_RECETOX_Vysledky_nove_studie_ukazaly_ze_mikroplasty_meni_vlastnosti_pudy_a_mikrobialni_spolecenstva_i_v_realnych_podminkach_6ee3413a7b.jpg 171w," sizes="100vw" width="738" height="674"></p><blockquote><h4><strong>Původní článek</strong></h4><h4><a target="_blank" rel="noopener noreferrer" href="https://www.sciencedirect.com/science/article/pii/S0269749125015866?via%3Dihub"><strong>Konvenční a biologicky rozložitelné zemědělské mikroplasty: vliv na půdní vlastnosti a mikrobiální funkce napříč evropským pedoklimatickým gradientem</strong></a></h4><p>Šmídová K., Soinne H., Kim S. W., Tirronniemi J., Meffe R., Redondo-Hasselerharm P. E., Braun M., Rillig M. C., Fritze H., Adamczyk B., Nikama J., Kaseva J., Saartama V., Amelung W., Hurley R., Hofman J., Nizzetto L., Selonen S., Velmala S.</p><p>Environ. Pollut. 386 (2025) 127212</p><p><a href="DOI:%2010.1016/j.envpol.2025.127212"><span>DOI:&nbsp;10.1016/j.envpol.2025.127212</span></a><a target="_blank" rel="noopener noreferrer" href="https://doi.org/10.1016/j.envpol.2025.127212"><span><svg></svg></span></a></p><h6>licencováno pod <a target="_blank" rel="noopener noreferrer" href="https://creativecommons.org/licenses/by/4.0/"><strong>CC-BY 4.0</strong></a></h6></blockquote><h4><strong>Abstrakt</strong></h4><p>Zemědělské plasty, jako jsou mulčovací fólie, se mohou během své degradace a fragmentace stát významným zdrojem kontaminace půdy mikroplasty (MP). Tato studie zkoumá vliv zemědělských mikroplastů z konvenčních (lineární polyethylen s nízkou hustotou, PE) a biologicky rozložitelných (směs škrob–poly(butylen adipate-co-tereftalát), PBAT-BD) mulčovacích fólií na fyzikálně-chemické vlastnosti půdy, půdní agregaci, mikrobiální diverzitu a funkce, rozklad odpadu a emise skleníkových plynů (GHG). Za tímto účelem byly mikroplasty přimíchány do půd v environmentálně realistických koncentracích 0,005 % a 0,05 % (hm. %) v roce 2022 na experimentálních plochách ve třech zemích EU reprezentujících rozdílné pedoklimatické podmínky (Finsko, Německo a Španělsko). Následně byly sledovány výše uvedené proměnné během vegetačních sezón 2022 a 2023. Byla zjištěna řada statisticky významných účinků mikroplastů na půdní vlastnosti, agregaci, mikrobiální diverzitu, rozklad odpadu a emise skleníkových plynů, avšak tyto efekty byly méně výrazné nebo vykazovaly značnou variabilitu mezi jednotlivými ukazateli. Naproti tomu mikrobiální aktivita, přispívající k půdním funkcím, jako je koloběh dusíku, byla konzistentně snížena jak konvenčními, tak biologicky rozložitelnými mikroplasty. Tyto poklesy byly výraznější po druhé vegetační sezóně a při vyšší koncentraci mikroplastů. Vzhledem k tomu, že vyšší koncentrace mikroplastů (tj. 0,05 % hm. %) je v evropském prostředí považována za relevantní, naše výsledky zdůrazňují potenciální dopady environmentálně relevantních koncentrací mikroplastů na zdraví půdy. Dále bylo pozorováno zesilování účinků od severu k jihu, pravděpodobně modulované rozdílnými pedoklimatickými podmínkami, což poukazuje na potřebu regionálně přizpůsobeného hodnocení rizik s cílem ochrany půd před plastovým znečištěním.</p>

Výsledky nové studie ukázaly, že mikroplasty mění vlastnosti půdy a mikrobiální společenstva i v reálných podmínkách

<p><strong>Zveme Vás na sérii krátkých, ale praktických online seminářů, které jsme připravili pro všechny, kdo pracují s chromatografií a laboratorní analýzou. Každý z webinářů je zameřený na jedno konkrétní analytické téma a nabídne jasné tipy, rešení nejčastejších problémů i doporučení.</strong></p><p>Již 13. 2. 2026 od 10:00 hodin se mužete tešit na téma: <strong>Sample Prep and Analysis for Fat-soluble Vitamins</strong>.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Altium_priprava_vzorku_pro_analyzu_vitaminu_rozpustnych_v_tucich_1b280b7ea1.jpg" alt="Altium - Agilent: Příprava vzorků pro analýzu vitamínů rozpustných v tucích – tipy a aplikace" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Altium_priprava_vzorku_pro_analyzu_vitaminu_rozpustnych_v_tucich_1b280b7ea1.jpg 245w," sizes="100vw" width="842" height="286"></p><blockquote><p class="cke-user_style-important"><a target="_blank" rel="noopener noreferrer" href="https://events.teams.microsoft.com/event/494d4b0d-da70-4504-9720-1bc7f82524fe@31139e4d-0687-4dc9-ada3-e46652ffbd94/registration"><strong>Registrujte se na webinář pomocí tohoto odkazu</strong></a></p></blockquote><p><strong>Vitamíny rozpustné v tucích jsou přirozenou součástí lipidové frakce potravin, kde se vyskytují společně s triglyceridy, steroly, fosfolipidy a dalšími lipidy. Tato „těsná spolupráce“ s ostatními tukovými složkami sice dává biochemický smysl, ale z analytického hlediska výrazně komplikuje jejich izolaci a přesné stanovení.</strong></p><p>Tradiční postupy přípravy vzorků jsou často časově náročné, pracné a náchylné k chybám, což se negativně promítá do reprodukovatelnosti i výtěžnosti analýzy. Řešení pro přípravu vzorků od společnosti Agilent Technologies tento problém mění v konkurenční výhodu: zjednodušují a urychlují celý pracovní postup, zajišťují konzistentní a reprodukovatelné výsledky a maximalizují výtěžnost analytů i v těch nejkomplexnějších matricích potravin a doplňků stravy.</p><p>Výsledkem je spolehlivější analytika, vyšší efektivita laboratoře a jistota dat, na která se lze skutečně spolehnout.</p><p><strong>Webinář bude probíhat v anglickém jazyce.</strong></p><blockquote><p><strong>Přednášející: </strong>EMEAI IDO (Product Specialist Chemistries and Supplies, Agilent Technologies)</p><p>Giorgio got his Master Degree in Chemistry at the University of Trieste, Italy.</p><p>He has more than 20 years of experience in Chromatography Columns troubleshooting, sales and business development.</p><p>He covered various international positions and at present is Agilent Product Specialist EMEAI-IDO, and responsible for developing the Agilent Chemistries and Supplies business in the indirect sales channels of Central Eastern Europe, Africa and the Middle East.</p></blockquote>

Altium - Agilent webinář: Příprava vzorků pro analýzu vitamínů rozpustných v tucích – tipy a aplikace

<p><strong>Vážení zákazníci a obchodní partneři,</strong></p><p><strong>rádi bychom vás informovali, že dnešním dnem 12. ledna 2026 nabývá účinnost část Vyhlášky 252/2004 Sb., o hygienických požadavcích na pitnou a teplou vodu a četnost a rozsah kontroly pitné vody, ve znění pozdějších předpisů.</strong></p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Lab_Rulez_AI_Rozbory_pitna_voda_ALS_CR_1_b7a65fb299/LabRulez-AI-Rozbory-pitna-voda-(ALS-CR)-1.jpg" alt="LabRulez/AI: Rozbory pitná voda  (ALS Čr) " srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Lab_Rulez_AI_Rozbory_pitna_voda_ALS_CR_1_b7a65fb299/thumbnail_LabRulez-AI-Rozbory-pitna-voda-(ALS-CR)-1.jpg 156w," sizes="100vw" width="815" height="815"></p><h4><strong>Co se mění?</strong></h4><p>12. ledna 2026 vstoupila v platnost novela Vyhlášky č. 252/2004 Sb., která rozšiřuje seznam chemických ukazatelů v příloze č.1, tabulky B o tyto ukazatele:</p><ul><li><strong>Řádek 20</strong> - Bisphenol A (BPA): Limitní hodnota 2,5 µg/l</li><li><strong>Řádek 29 </strong>- Halogenoctové kyseliny (HAA): Limitní hodnota 60 µg/l<br>(limitní hodnota se vztahuje na součet kvantitativně zjištěných koncentrací kyselin: chloroctová, dichloroctová, trichloroctová, bromoctová a dibromoctová)</li><li><strong>Řádek 52</strong> - Suma PFAS: Limitní hodnota: 0,10 µg/l<br>(suma PFAS zahrnuje: PFBA, PFPA, PFHxA, PFHpA, PFOA, PFNA, PFDA, PFUnDA, PFDoDA, PFTrDA, PFBS, PFPS, PFHxS, PFHpS, PFOS, PFNS, PFDS, perfluoroundekansulfonová kyselina, perfluorododekansulfonová kyselina, perfluorotridekansulfonová kyselina)</li></ul><blockquote><p><strong>Podrobné znění vyhlášky naleznete </strong><a target="_blank" rel="noopener noreferrer" href="https://www.zakonyprolidi.cz/cs/2004-252/zneni-20260112"><strong>zde</strong></a>.</p></blockquote><ul><li>Od dnešního dne tedy musí být tyto parametry zahrnuty do pravidelných kontrol pitné vody.</li><li>Laboratoře ALS Czech Republic již nabízí <a target="_blank" rel="noopener noreferrer" href="https://lcms.cz/products/991"><strong>rozbory pitných vod v plném rozsahu dle této vyhlášky</strong></a>.</li></ul><p><strong>Kontaktujte nás!</strong></p><p>Máte dotazy ohledně nových parametrů a požadavků? Potřebujete poradit s implementací?</p><blockquote><p class="cke-user_style-important">Jsme tu pro vás! Neváhejte nás kontaktovat na e-mailu: <strong>info.cz@alsglobal.com</strong> nebo na tel.: <strong>+420 226 226 228</strong></p></blockquote>

Nové limity pro testování pitné vody

Webináře

Plasty

Životní prostředí

Potraviny

Vody

Článek

Laboratoře

Centrum je samostatným ústavem Přírodovědecké fakulty Masarykovy univerzity, který realizuje výzkum, vývoj, výuku a expertní činnost v oblasti znečištění prostředí toxickými látkami. Předmětem zájmu jsou především perzistentní organické polutanty (POPs), polární organické látky, toxické kovy a jejich specie, přírodní toxiny (cyanotoxiny).

RECETOX - Centrum pro výzkum toxických látek v prostředí

Základním posláním společnosti ALS je pomáhat našim klientům se kvalifikovaně a informovaně rozhodovat tím, že poskytuje spolehlivá, konzistentní a reprodukovatelná laboratorní data. Zaručujeme spolehlivé výsledky, krátké dodací lhůty, nepřetržitý provoz, odbornou podporu a odběry vzorků.

ALS Czech Republic

Je autorizovaným distributorem společnosti Agilent Technologies pro Českou republiku v oblastech chromatografie (GC, HPLC, UHPLC, kapilární elektroforéza) a hmotnostní spektrometrie (GC/MS, LC/MS, CE/MS), disolučních aparátů, molekulární (UV-Vis, UV-Vis-NIR, fluorescence, FTIR analyzátory a mikroskopy) a atomové spektroskopie (ICP-OES, ICP-MS, AAS), a v neposlední řadě také v oblasti molekulární biologie a genomiky (analýza nukleových kyselin a proteinů, microarray skenery a skla, PCR & RT-PCR, qPCR, řešení pro NGS, reagencie pro mutagenezi a klonování, sondy FISH a další).

Altium International

Metrohm

Agilent Technologies

Technology Networks

Thermo Fisher Scientific

SelectScience

SCIEX

Waters Corporation

<div><p><strong>As GLP-1 receptor agonists (GLP-1RAs) continue to transform the treatment landscape for metabolic disorders, ensuring the integrity and quality of these complex molecules is more critical than ever. This webinar explores advanced analytical strategies for characterizing critical quality attributes (CQAs), with a focus on Size-Exclusion Chromatography with Multi-Angle Light Scattering (SEC-MALS) and Reversed-Phase Chromatography with Mass Spectrometry (RPC-MS).</strong></p><p>Attendees will gain insights into <strong>SEC column</strong> <strong>selection</strong> for impurity profiling, the use of native vs. denaturing SEC for aggregation analysis, and the comparative strengths of <strong>MALS and MS detection</strong>. The session also features a side-by-side analysis of liraglutide and semaglutide, demonstrating how integrated data workflows using Empower CDS with MALS streamline complex analyses while supporting compliance requirements and product quality.</p><p>With built-in tools for method standardization, secure data handling, and audit-trail integrity, Empower CDS helps laboratories meet regulatory expectations while improving efficiency. Whether you're developing or monitoring GLP-1RAs, this session offers practical guidance and best practices using the Waters end-to-end LC, column, detector, and software solutions.</p><h5><strong>Key Learning Objectives:</strong></h5><ul><li>Understand critical quality attributes (CQAs) for GLP-1 receptor agonists</li><li>Explore column selection strategies for SEC and RPC</li><li>Compare MALS and MS detection techniques for aggregation and purity analysis</li><li>Learn how Empower CDS supports compliance-ready, unified data workflows</li></ul><h5><strong>Who Should Attend:</strong></h5><ul><li>Scientists and Researchers in QC working in GLP-1 RA and other peptide therapeutics</li><li>Lab Managers looking to understand state-of-the-art instruments for enhancing analytical capabilities in their labs</li><li>Regulatory affairs specialists focused on CQA and compliance<br>&nbsp;</li></ul><blockquote><p><strong>Presenter:</strong> Bill Warren (Waters Corporation)</p><p>Bill Warren is Principal Product Marketing Manager within Waters Consumables and Automation Group. Over his 36-year tenure at Waters, he has developed various biomolecule applications and has helped manage a comprehensive line of bioseparation consumables for DNA/RNA, amino acid, peptide, protein, and glycan applications. His current focus is on chemistry consumables for proteins, DNA/RNA, and cell therapy-related applications.</p><p><strong>Presenter:</strong> Neil J. Lander (Principal Product Manager)</p><p>Neil is a has worked for Waters Corporation since 1994 and currently serves as a Principal Product Manager in the Informatics group. Neil provides support for Empower CDS software and is focused on developing laboratory software solutions that help organizations achieve their scientific and operational objectives. Prior to joining Waters Corporation, he was an analytical chemist where he gained experience in both the cosmetics and specialty chemical industries.</p></blockquote></div>

Waters Corporation: From Aggregation to Impurity Profiling: Analytical Best Practices for GLP-1RAs

From Aggregation to Impurity Profiling: Analytical Best Practices for GLP-1RAs

Learn how SEC-MALS and RPC-MS improve GLP-1RA quality analysis. Discover compliant, integrated workflows with Empower CDS for CQAs

Analytical Best Practices for GLP-1RAs

<div><div container-id="cq-colctrl-lt0" comp-id="A1"><div><p><strong>Processing an ever-growing number of blood samples in clinical labs places constant pressure on laboratory staff, workflows, and instrumentation to deliver accurate, high-throughput results with minimal turnaround time.</strong></p><p>Traditional LC-MS/MS workflows are used to analyze blood samples and though they are highly sensitive and specific, they often require experienced personnel, manual sample preparation, and time-consuming data handling.</p><p>Discover in this exciting webinar how automation can transform these bottlenecks. Hear from Dr. Frank Streit from University Medical Center Göttingen, as he discusses how a Clinical Laboratory Automated Module (CLAM) can streamline processes from barcode scanning and Laboratory Information System (LIS)-driven test selection, to sample prep, analysis, and result reporting.</p><h5><strong>Key learning objectives</strong></h5><ul><li>Understand how the <strong>CLAM-2040</strong> enables full automation of LC-MS/MS workflows, from barcode scanning to result reporting.</li><li>Find out how the integration of the CLAM-2040 with LIS systems via HL7 interface offers seamless data exchange and test request handling.</li><li>Recognize the advantages of 24/7 unattended operation for high-throughput clinical testing environments.</li><li>Discover how non-expert technicians can perform complex LC-MS/MS analyses without specialized mass spectrometry or chromatography training.</li></ul><h5><strong>Who should attend?</strong></h5><ul><li>Clinical laboratory professionals involved in diagnostic testing, including lab managers, medical technologists, and clinical scientists seeking to streamline LC-MS/MS workflows and increase throughput.</li><li>Healthcare and clinical decision-makers including pathologists, clinical chemists, and laboratory directors interested in adopting automated, scalable mass spectrometry solutions.</li></ul><h5><strong>Certificate of attendance</strong></h5><ul><li>If you attend the live webinar, you will automatically receive a certificate of attendance, including a learning outcomes summary, for continuing education purposes.</li><li>If you view the on-demand webinar, you can request a certificate of attendance by emailing editor@selectscience.net.</li></ul><blockquote><p><strong>Presenter: </strong>Dr. Frank Streit (Head of Clinical Research, University Medical Center Göttingen)</p><p>Dr. Frank Streit established LC-MS/MS methods for the quantification of immunosuppressants in the mass spectrometry laboratory at the University of Göttingen. He started LC-MS/MS routine quantification of sirolimus and everolimus in 1999 and of tacrolimus and ciclosporin in 2004. To date, he has led the development of LC-MS/MS methods for the quantification of more than 300 compounds for therapeutic drug monitoring.</p><p><strong>Moderator:</strong> Olivia Long (Editorial Team, SelectScience)</p></blockquote></div></div></div>

SelectScience: Transforming LC-MS/MS blood sample processing for faster clinical results

Transforming LC-MS/MS blood sample processing for faster clinical results

Learn how CLAM-2040 automation streamlines LC-MS/MS blood testing, enabling faster, high-throughput results with minimal manual intervention.

Faster Clinical Results with Automated Blood Processing

<p><strong>Agilent HPLC and UHPLC systems are renowned for their robustness and reliability. What if you could combine this proven performance with greater efficiency—saving time and reducing manual effort?</strong></p><p>Join us for an exclusive webinar showcasing the latest innovations in the Agilent Infinity III LC Series helping you to achieve confidence in results.</p><h5><strong>What you’ll learn:</strong></h5><ul><li><strong>Discover how the Agilent InfinityLab Assist</strong> and other new hardware and software features help automate routine tasks, support maintenance, and extend instrument lifespan</li><li><strong>Watch a demo of Agilent InfinityLab Level Sensing</strong> for automated solvent monitoring—helping you prevent costly repeat analyses</li><li><strong>See the latest additions to our LC and LC/MS portfolio,</strong> including the Agilent InfinityLab Pro iQ mass detector, 1290 Infinity III FLD, and 1290 Infinity III Hybrid Multisampler—and learn how they support your specific analytical needs</li></ul><p><i>If you’re looking to achieve reliable results with less effort, this is a session you won’t want to miss.</i></p><blockquote><p><strong>Presenter:</strong> Dr. Lorraine Kay (Product Manager at Agilent Technologies Inc.)</p><p>Lorraine Kay is a product manager in the Liquid Phase Division. She holds a degree in microbiology and a PhD in metabolomics from the University of Dundee, Scotland. With deep expertise in hyphenated and multidimensional separation techniques, along with strong B2B experience, Lorraine has successfully held various commercial roles across the analytical sciences sector.</p><p><strong>Presenter: </strong>Jade Byrd (Director of Industry Marketing and Applications, Agilent Technologies)</p><p>Jade has worked with laboratory-driven organizations implementing LC and LC/MS solutions for 19 years, first as an applications chemist and then as a product manager. Prior to working for LC vendors, Jade worked in the pharmaceutical space doing routine analysis and software-assisted chromatographic method development and validation. Today, Jade works to ensure that Agilent InfinityLab LC Solutions meet both the technical and business needs of her user communities, which include the (bio-) pharmaceutical, environmental, research, food, chemical, and energy markets and she is passionate about LC and LC/MS.</p><p><strong>Presenter: </strong>Dr. Sonja Schipperges (Application Scientist, Agilent Technologies Inc.)</p><p>Sonja Schipperges is an application scientist in Agilent's Liquid Phase Division. In this role, she develops application notes for LC and LC-MS, with a special focus on the Infinity III LC and 2D-LC. Sonja studied food chemistry and holds a doctorate in analytical chemistry from the University of Wuppertal, Germany.</p></blockquote>

Agilent Technologies: Say Hello to More Confidence in Your HPLC Results

Say Hello to More Confidence in Your HPLC Results

Join us for an exclusive webinar showcasing the latest innovations in the Agilent Infinity III LC Series helping you to achieve confidence in results.

<div><div container-id="cq-colctrl-lt0" comp-id="A1"><div><p><strong>Analyzing polar molecules presents unique challenges for chromatographers. These compounds span a wide range of applications from polar pesticides in food, to non-steroidal anti-inflammatory drugs (NSAIDs), to highly polar sugars and amino acids. Traditional HPLC stationary phases like C18 often fall short in retaining and separating such highly polar analytes. As a result, chromatographers must explore alternative polar chemistries, including reverse-phase polar columns and hydrophilic interaction liquid chromatography (HILIC) &amp; normal phases.</strong></p><p>In this webinar, we will provide practical guidelines for selecting the appropriate separation mode, HILIC, reverse phase (RP), or normal, based on analyte properties and application needs. We’ll walk through a structured checklist to help you make informed decisions when developing methods for polar molecule separations.</p><h5><strong>Key Takeaways:</strong></h5><ul><li>How to select the best column for retaining and separating polar analytes, with a focus on Reverse Phase &amp; HILIC chemistries</li><li>Choosing between Reverse Phase and HILIC based on analyte solubility and sample solvent</li><li>Ensuring reliable detection through the right separation mode</li><li>Selecting the appropriate column type (SPP or TPP) based on the application</li><li>Method optimization strategies for improved results</li></ul><blockquote><p><strong>Presenter: </strong>Dr. Sunil B Lakhmapure (Pre-Sales Application Engineer, Agilent Technologies)</p><p>Sunil holds 19 year plus experience in the analytical field with major exposure to LC/GC with Single Quad, Triple Quad and high resolution (QToF) mass spectroscopy. Started career in Pharma R&amp;D as a scientist with hands on experience on high end instruments like LC/MS, XRD &amp; NMR. Developed &amp; published application notes using Chromatographic techniques on real world samples/issues at various levels.</p><p><strong>Presenter:&nbsp;</strong>Mr. Andrea Leonardi (Product Specialist, Chemistries &amp; Supplies, Agilent Technologies)</p><p>Andrea holds a master's degree in Pharmaceutical Chemistry and Technology form Universita’ degli Studi di Camerino in Central Italy. Since completing his studies, he has held various laboratory and research roles with pharmaceutical companies in Italy and Switzerland, before coming to Singapore to join Novartis Institute for Tropical Diseases. This latest job involved characterizing novel APIs (Active Pharmaceutical Ingredients) by LC and LC/MS.</p><p>In Agilent, Andrea is a Product Specialist in the Chemistries and Supplies Division in the South-East Asia Pacific and Korea region. He supports customers by helping to develop new analytical methods and improve existing ones to enhance lab efficiency and productivity. He also conducts training, seminars, and workshops. His expertise is in LC and LC/MS analysis of small molecules and biologics.</p></blockquote></div></div></div>

Agilent Technologies: The Polar Puzzle: Solving Complex Analytical Challenges

The Polar Puzzle: Solving Complex Analytical Challenges

Practical guidelines for selecting the appropriate separation mode, HILIC, reverse phase (RP), or normal, based on analyte properties and application needs. 

<div><div container-id="cq-colctrl-lt0" comp-id="A1"><div><p><strong>From pharmaceuticals to environmental samples, UV-Vis spectroscopy confirms chemical identities and quantifies biomolecules to provide insights into sample purity, conformational changes in proteins and reaction kinetics.</strong></p><p>This webinar takes a deep dive into the applications and science behind UV-Vis spectroscopy, highlighting how this approach can be engineered for high-performance labs demanding precision, flexibility and durability.</p><p>Our expert speaker will introduce the Cary 3500 UV-Vis spectrophotometer from Agilent, exploring the system’s advanced features and how they could benefit your research, including fiber optic coupling and the capacity to perform simultaneous multi-cell measurements.</p><h5><strong>Attend this webinar to:</strong></h5><ul><li>Understand how UV-Vis spectroscopy improves analytical efficiency</li><li>Learn how the Cary 3500 UV-Vis spectrophotometer accommodates diverse sample types and ultra-fast data acquisition</li><li>Hear how UV-Vis spectroscopy can benefit sensitive workflows, remote analysis and regulatory compliance</li></ul><blockquote><p><strong>Presenter: </strong>Marion Börger, PhD (Product Specialist, Molecular Spectroscopy at Agilent Technologies)</p><p>Marion Börger is a product specialist for molecular spectroscopy. She studied chemistry and received her PhD for infrared spectroscopic studies of biomembranes. Marion has over twenty years of experience in infrared spectroscopy. She began her work as an application chemist for Bio-Rad and has worked for Agilent Technologies since 2002.</p></blockquote></div></div></div>

Agilent Technologies: Driving Analytical Precision With UV-Vis Spectroscopy

Driving Analytical Precision With UV-Vis Spectroscopy

Explore UV-Vis spectroscopy with Agilent Cary 3500. Gain insights into fast, flexible, and precise analysis for diverse research workflows.

<div><div container-id="cq-colctrl-lt0" comp-id="A1"><div><p><strong>Discover the power of combustion-ion chromatography (C-IC) in our upcoming webinar! This event will explore the theory and instrumentation behind C-IC, with a focus on its application in analyzing halogens, sulfur, and per- and polyfluoroalkyl substances (PFAS).</strong></p><h5><strong>Key highlights:</strong></h5><ul><li><strong>Theory and instrumentation: </strong>Gain an understanding of C-IC technology.</li><li><strong>Application insights:</strong> Learn how C-IC excels in analyzing halogens, sulfur, and PFAS screening.</li><li><strong>Unmatched benefits: </strong>Understand the sensitivity and versatility of C-IC in handling diverse sample matrices.</li><li><strong>Overcoming challenges:</strong> Address common issues such as matrix effects and interferences.</li><li><strong>Best practices: </strong>Get expert tips on optimizing sample preparation and analysis.</li></ul><p>Don't miss this opportunity to enhance your knowledge and skills in combustion-ion chromatography. Register now and take your analytical capabilities to the next level!</p><p>We look forward to seeing you there!</p><blockquote><p><strong>Presenter: </strong>Terri Christison (Application Staff Scientist, Thermo Fisher Scientific)</p><p>Terri Christison is an Applications Staff Scientist at Thermo Fisher Scientific with 20 years of experience, specializing in Ion Chromatography applications for various markets. Recently, she has focused on advancing combustion-IC applications for environmental and chemical markets. Previously, she spent 15 years in the electronics industry conducting material and failure analysis. She holds bachelor's degrees in chemistry and biology from California State University-Fresno.</p><p><strong>Moderator: </strong>Dr. Carl Fisher (Product Marketing Manager, Thermo Fisher Scientific)</p><p>Dr. Carl Fisher is a Product Marketing Manager in the Ion Chromatography/Sample Preparation (IC/SP) business unit of Thermo Fisher Scientific, focusing on delivering intuitive, reliable IC and sample preparation solutions for routine analyses.</p></blockquote></div></div></div>

Thermo Fisher Scientific: Unlocking the Power of Combustion-Ion Chromatography

Unlocking the Power of Combustion-Ion Chromatography

Join Thermo Fisher’s webinar on C-IC. Discover theory, instrumentation, and applications for halogens, sulfur, and PFAS with expert insights and tips.

Power of Combustion-Ion Chromatography

<p><strong>Laboratories today face growing sample volumes and complex workflows that challenge both efficiency and accuracy. Manual sample preparation and analysis can quickly become a bottleneck and lead to inconsistencies, especially when performed by different individuals: The risk of human errors increases.</strong></p><p>In an upcoming webinar on September 17, Dr. Julian Weber, Product Specialist for Titration Automation at Metrohm International Headquarters, will demonstrate how automation can help you overcome these challenges. You will also see real-world examples of fully automated titration workflows, including parallel determination of multiple different parameters, demonstrating how modern automation solutions can significantly boost your lab's performance.</p><p>Register for this event and learn how to streamline your routine analysis, improve data quality, and free up valuable laboratory resources with titration automation!</p><h5><strong>What you will learn:</strong></h5><ul><li>How to significantly increase sample throughput</li><li>How to systematically minimize human error</li><li>Techniques how to enhance precision and reproducibility</li><li>Best practice for improving compliance with lab safety standards</li></ul><h5><strong>Who should attend?</strong></h5><ul><li>Lab managers, lab technicians, chemists, and everybody else interested in laboratory automation</li></ul><blockquote><p><strong>Presenter: </strong>Dr. Julian Weber (Product Specialist Titration, Metrohm International Headquarters)</p><p>Dr. Julian Weber earned his PhD in 2022 at the University of Konstanz in Physical Chemistry. He joined Metrohm International Headquarters in 2023 as Product Specialist for Titration Tutomation. Since then, he has gained an extensive experience in automation for all kind of titration systems working for the Competence Center Titration at Metrohm International Headquarters.</p></blockquote>

Metrohm: Struggling with Titration Overload? Learn how Automation can help!

Struggling with Titration Overload? Learn how Automation can help!

Learn how titration automation streamlines workflows, minimizes errors, and enhances precision for modern labs.

Struggling with Titration Overload? Automation help

<div><div container-id="cq-colctrl-lt0" comp-id="A1"><div><p><strong>Phosphopeptide analysis is a critical aspect of understanding cellular signaling and disease mechanisms, yet it comes with its own set of challenges. Phosphopeptides are often present in low abundance compared to their non-phosphorylated counterparts, requiring an enrichment step as part of the sample preparation protocol. Phosphopeptides can be difficult to ionize and fragment efficiently in mass spectrometry, and specific instrument method settings should be employed to address that. Data analysis and interpretation is complicated as well, due to the presence of multiple phosphorylation sites on a single peptide and the potential for different phosphorylation states (e.g., mono-, di-, or tri-phosphorylation).</strong></p><p>Addressing these challenges involves optimizing sample preparation protocols, using advanced mass spectrometry techniques, and employing robust bioinformatics tools to ensure accurate and comprehensive phosphopeptide analysis. This workshop will provide you with valuable insights and practical solutions to overcome these hurdles, enhancing your research capabilities.</p><h5><strong>What You Will Learn:</strong></h5><ul><li>Strategies for enriching low-abundance phosphopeptides</li><li>Techniques to minimize phosphate group loss during sample preparation</li><li>Advanced mass spectrometry methods for efficient phosphopeptide detection</li><li>Best practices for data interpretation and bioinformatics analysis</li><li>Case studies with hands-on data processing examples</li></ul><p>The workshop is aimed at both novice and intermediate users. We planned time at the end of the workshop to answer our questions.</p><h5><strong>14:00 BST / 15:00 CEST – Welcome and start of the workshop</strong></h5><h5><strong>14:05 BST / 15:05 CEST – Sample preparation (Leigh Foster)</strong></h5><ul><li>Overview of workflows and products</li><li>Cleanup considerations</li><li>Enrichment methods</li><li>Special applications</li></ul><h5><strong>14:55 BST / 15:55 CEST – LC-MS acquisition methods (Jenny Ho)</strong></h5><ul><li>Fragmentation techniques for phosphopeptide characterization</li><li>Relative quantitation (TM, DIA)</li></ul><h5><strong>15:45 BST / 16:45 CEST – Data processing (Michaela Scigalova)</strong></h5><ul><li>Decision tree based on acquisition parameters</li><li>Workflows and parameter settings</li><li>Visualization of results</li><li>Relative quantitation of TMT-labeled phosphopeptides</li></ul><h5><strong>16:30 BST / 17:30 CEST – Close</strong></h5><p>You are unable to attend the webinar broadcast on September 17? Please register anyway to automatically receive the link to the recording.</p><blockquote><p><strong>Presenter: </strong>Leigh Foster (Scientist, Mass Spectrometry and Immunoassay Systems, Thermo Fisher Scientific)</p><p>Leigh Foster is a Scientist at Thermo Fisher Scientific. Her experience is in protein biology and she works in mass spectrometry reagent product development group based in Rockford, Illinois.</p><p><strong>Presenter:&nbsp;</strong>Jenny Ho (Sr. Lab Application Scientist, LCMS Proteomics, Thermo Fisher Scientific)</p><p>Jenny Ho is a senior proteomics applications specialist at Thermo Fisher Scientific based in the Life Science Mass Spectrometry demonstration facility, in the UK.</p><p><strong>Presenter:&nbsp;</strong>Michaela Scigelova (Product Support, Thermo Fisher Scientific)</p><p>Michaela provides customer support to Thermo Scientific Proteome Discoverer software users.</p></blockquote></div></div></div>

Thermo Fisher Scientific: Proteome Discoverer Phosphopeptides Workshop

Proteome Discoverer Phosphopeptides Workshop

Practical solutions for phosphopeptide enrichment, LC-MS analysis, and data interpretation in a Thermo Fisher Scientific workshop with expert case studies.

<p><strong>Join us to explore the versatile power of the QTRAP LC-MS/MS system in food analysis and contaminant detection, including phytochemical profiling, targeted/untargeted analysis, trace contaminant detection, food authenticity, and nutraceutical development.</strong></p><h5><strong>Key highlights:</strong></h5><ul><li>QTRAP LC-MS/MS system in enabling comprehensive phytochemical analysis in food and fruits</li><li>Validated sMRM quantitation of essential health-promoting phytomarkers</li><li>Untargeted and targeted procedures to define the extensive phytochemistry of food</li><li>Capability to identify contaminants such as pesticid and, drug contaminants at trace levels</li></ul><blockquote><p><strong>Presenter: </strong>Dr. Pratibha Srivastava (Agharkar Research Institute)</p></blockquote>

SCIEX: QTRAP LC-MS/MS system: a versatile platform for food analysis and contaminant detection

QTRAP LC-MS/MS system: a versatile platform for food analysis and contaminant detection

Join us to explore the versatile power of the QTRAP LC-MS/MS system in food analysis and contaminant detection.

QTRAP LC-MS/MS for food analysis and contaminant detection

<div><div container-id="cq-colctrl-lt0" comp-id="A1"><div><p><strong>This is the first webinar of a two-part series.</strong></p><p>Join us for an insightful webinar where we explore the cutting-edge SQUAD approach to nitrosamine and NDSRI testing. This innovative method focuses on confidently annotating and accurately quantifying a targeted set of compounds using authentic standards and calibration curves. Simultaneously, it performs untargeted analysis to identify novel impurities, all within a single injection, resulting in unparalleled laboratory efficiency.</p><h5><strong>Key Topics covered:</strong></h5><ul><li><strong>SQUAD Approach:</strong> Learn how the SQUAD approach revolutionizes nitrosamine and NDSRI analysis by combining targeted and untargeted methods for comprehensive impurity detection</li><li><strong>Mass Spectrometry (MS): </strong>Discover why MS is the analytical tool of choice for analyzing pharmaceutical products and active pharmaceutical ingredients (API) with high selectivity and sensitivity</li><li><strong>Challenges in Nitrosamine Testing:</strong> Understand the distinct difficulties in analyzing small NAs with very low acceptable intake limits (AI) and NDSRIs with unknown structures</li></ul><blockquote><p><strong>Presenter: </strong>Jessica Hoskins, PhD (Principal Research Scientist I, Predictive Stability and Structure Elucidation)</p><p>Jessica is a Principal Research Scientist at AbbVie where she and her team focus on Predictive Stability and Structure Elucidation to understand degradation pathways and other potential stability limiting attributes for new synthetic molecule drug substances and drug products. She has a PhD in Organic Chemistry from Tulane University with Scott Grayson, where she first became interested in mass spectrometry for polymers. Prior to joining AbbVie, she was an Adolf Martens Postdoctoral Fellow at the Federal Institute for Materials Research and Testing (BAM) in Berlin, Germany, and worked as an analytical chemist at Stepan Company in the surfactant and polymer industry.</p><p><strong>Presenter:&nbsp;</strong>Sebastien Morin (Sr Manager, Business Development, Thermo Scientific)</p><p>Sebastien is a Senior Manager, Business Development at Thermo Fisher Scientific where he partners closely with Pharma and Biopharma Companies to address analytical challenges. He holds a M. SC. in Organic Chemistry from Universite de Montreal. Prior to joining Thermo Fisher Scientific, he was a Research Associate, Medicinal Chemistry for Boehringer Ingelheim, advancing virology research.</p><p><strong>Moderator:</strong> Jon Bardsley (Market Development Manager, Thermo Fisher Scientific)</p></blockquote></div></div></div>

Thermo Fisher Scientific: Amplify laboratory efficiency for known and unknown nitrosamines - Simultaneous QUAntitation and Discovery (SQUAD)

Amplify laboratory efficiency for known and unknown nitrosamines - Simultaneous QUAntitation and Discovery (SQUAD)

Learn how the SQUAD method boosts nitrosamine analysis by combining targeted quantitation and untargeted impurity discovery in a single injection.

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